USO DO CLORIDRATO DE CICLOBENZAPRINA E ACECLOFENACO NO TRATAMENTO DA DISFUNÇÃO TEMPOROMANDIBULAR: UM ENSAIO CLÍNICO RANDOMIZADO

• Autor(a) principal: Rocha, Lorenzo Fogliarini da
• Data de Publicação: 2023
• Tipo de documento: Dissertação
• Idioma: por
• Título da fonte: Repositório Institucional Universidade Franciscana
• Texto Completo: http://www.tede.universidadefranciscana.edu.br:8080/handle/UFN-BDTD/1259
• topic: Disfunção temporomandibular; Dor orofacial; Terapia Farmacológica.; Temporomandibular dysfunction; Orofacial pain; Pharmacological Therapy.; Ciências da Saúde e da Vida

Temporomandibular dysfunction (TMD) is one of the disorders that affects the stomatognathic system of patients, directly impacting their quality of life. The aim of this clinical study was to evaluate the effectiveness of a conservative approach using a combined pharmacological therapy of muscle relaxant (cyclobenzaprine hydrochloride) and anti-inflammatory (aceclofenac) for the treatment of temporomandibular dysfunction symptoms. Parameters such as mouth opening measurement and pain pressure threshold were utilized. Thirty-five patients were evaluated, comprising 20 in the test group and 15 in the placebo group, with 25 women and 10 men (40.1 ± 11.4 years). Both groups showed improved mouth opening, decreased intensity of provoked pain, and enhanced oral health-related quality of life (p < 0.001) in the first 14 days. However, between the second and third evaluations, there was no statistically significant improvement for any of the assessed outcomes.