Simulating inbreeding depression through the mutation accumulation theory.

Detalhes bibliográficos
Autor(a) principal: Sousa, Adriano de Oliveira
Data de Publicação: 2000
Outros Autores: Oliveira, Suzana Maria Moss de, Bernardes, Américo Tristão
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFOP
Texto Completo: http://www.repositorio.ufop.br/handle/123456789/836
Resumo: Using the Penna model for biological aging, which is based on the mutation accumulation theory, we show that the number of homozygous loci corresponding to deleterious mutations is higher in small populations than in large ones. This decrease of heterozygosity may drive small populations to extinction even when no drastic change of the environment occurs.
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spelling Sousa, Adriano de OliveiraOliveira, Suzana Maria Moss deBernardes, Américo Tristão2012-06-14T16:17:49Z2012-06-14T16:17:49Z2000SOUSA, A. de O.; OLIVEIRA, S. M. M de; BERNARDES, A. T. Simulating inbreeding depression through the mutation accumulation theory. Physica A, v. 278, p.563-570, 2000. Disponível em: <http://www.daimi.au.dk/~tbata/tap/BataillonKirk.pdf>. Acesso em: 14 jun. 2012.03784371http://www.repositorio.ufop.br/handle/123456789/836Using the Penna model for biological aging, which is based on the mutation accumulation theory, we show that the number of homozygous loci corresponding to deleterious mutations is higher in small populations than in large ones. This decrease of heterozygosity may drive small populations to extinction even when no drastic change of the environment occurs.AgeingPenna modelMonte Carlo simulationsSimulating inbreeding depression through the mutation accumulation theory.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleO Periódico Physica A concede permissão para depósito do artigo no Repositório Institucional da UFOP. Número da licença: 3286990828950.info:eu-repo/semantics/openAccessengreponame:Repositório Institucional da UFOPinstname:Universidade Federal de Ouro Preto (UFOP)instacron:UFOPLICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://www.repositorio.ufop.br/bitstream/123456789/836/5/license.txt8a4605be74aa9ea9d79846c1fba20a33MD55ORIGINALARTIGO_SimulatingInbreedingDepression.pdfARTIGO_SimulatingInbreedingDepression.pdfapplication/pdf249380http://www.repositorio.ufop.br/bitstream/123456789/836/1/ARTIGO_SimulatingInbreedingDepression.pdf59c26ac36469d3c27872bdeefc4efed5MD51123456789/8362017-01-13 10:52:17.794oai:localhost: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Repositório InstitucionalPUBhttp://www.repositorio.ufop.br/oai/requestrepositorio@ufop.edu.bropendoar:32332017-01-13T15:52:17Repositório Institucional da UFOP - Universidade Federal de Ouro Preto (UFOP)false
dc.title.pt_BR.fl_str_mv Simulating inbreeding depression through the mutation accumulation theory.
title Simulating inbreeding depression through the mutation accumulation theory.
spellingShingle Simulating inbreeding depression through the mutation accumulation theory.
Sousa, Adriano de Oliveira
Ageing
Penna model
Monte Carlo simulations
title_short Simulating inbreeding depression through the mutation accumulation theory.
title_full Simulating inbreeding depression through the mutation accumulation theory.
title_fullStr Simulating inbreeding depression through the mutation accumulation theory.
title_full_unstemmed Simulating inbreeding depression through the mutation accumulation theory.
title_sort Simulating inbreeding depression through the mutation accumulation theory.
author Sousa, Adriano de Oliveira
author_facet Sousa, Adriano de Oliveira
Oliveira, Suzana Maria Moss de
Bernardes, Américo Tristão
author_role author
author2 Oliveira, Suzana Maria Moss de
Bernardes, Américo Tristão
author2_role author
author
dc.contributor.author.fl_str_mv Sousa, Adriano de Oliveira
Oliveira, Suzana Maria Moss de
Bernardes, Américo Tristão
dc.subject.por.fl_str_mv Ageing
Penna model
Monte Carlo simulations
topic Ageing
Penna model
Monte Carlo simulations
description Using the Penna model for biological aging, which is based on the mutation accumulation theory, we show that the number of homozygous loci corresponding to deleterious mutations is higher in small populations than in large ones. This decrease of heterozygosity may drive small populations to extinction even when no drastic change of the environment occurs.
publishDate 2000
dc.date.issued.fl_str_mv 2000
dc.date.accessioned.fl_str_mv 2012-06-14T16:17:49Z
dc.date.available.fl_str_mv 2012-06-14T16:17:49Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SOUSA, A. de O.; OLIVEIRA, S. M. M de; BERNARDES, A. T. Simulating inbreeding depression through the mutation accumulation theory. Physica A, v. 278, p.563-570, 2000. Disponível em: <http://www.daimi.au.dk/~tbata/tap/BataillonKirk.pdf>. Acesso em: 14 jun. 2012.
dc.identifier.uri.fl_str_mv http://www.repositorio.ufop.br/handle/123456789/836
dc.identifier.issn.none.fl_str_mv 03784371
identifier_str_mv SOUSA, A. de O.; OLIVEIRA, S. M. M de; BERNARDES, A. T. Simulating inbreeding depression through the mutation accumulation theory. Physica A, v. 278, p.563-570, 2000. Disponível em: <http://www.daimi.au.dk/~tbata/tap/BataillonKirk.pdf>. Acesso em: 14 jun. 2012.
03784371
url http://www.repositorio.ufop.br/handle/123456789/836
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFOP
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instacron:UFOP
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instacron_str UFOP
institution UFOP
reponame_str Repositório Institucional da UFOP
collection Repositório Institucional da UFOP
bitstream.url.fl_str_mv http://www.repositorio.ufop.br/bitstream/123456789/836/5/license.txt
http://www.repositorio.ufop.br/bitstream/123456789/836/1/ARTIGO_SimulatingInbreedingDepression.pdf
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