Production of L-asparaginase by filamentous fungi

Detalhes bibliográficos
Autor(a) principal: SARQUIS, Maria Inez de Moura
Data de Publicação: 2004
Outros Autores: OLIVEIRA, Edna Maria Morais, SANTOS, Alberdan Silva, COSTA, Gisela Lara da
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFPA
DOI: 10.1590/S0074-02762004000500005.
Texto Completo: http://repositorio.ufpa.br/jspui/handle/2011/3310
Resumo: L-asparaginase production was investigated in the filamentous fungi Aspergillus tamarii and Aspergillus terreus. The fungi were cultivated in medium containing different nitrogen sources. A. terreus showed the highest L-asparaginase (activity) production level (58 U/L) when cultivated in a 2% proline medium. Both fungi presented the lowest level of L-asparaginase production in the presence of glutamine and urea as nitrogen sources. These results suggest that L-asparaginase production by of filamentous fungi is under nitrogen regulation.
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spelling 2013-01-14T15:36:13Z2013-01-14T15:36:13Z2004-08SARQUIS, Maria Inez de Moura, et al. Production of L-asparaginase by filamentous fungi. Memória do Instituto Oswaldo Cruz. Rio de Janeiro, v. 99, n.5, p. 489-492, ago. 2004. Disponível em: <http://www.scielo.br/pdf/mioc/v99n5/v99n5a05.pdf>. Acesso em: 10 dez. 2013. http://dx.doi.org/10.1590/S0074-02762004000500005.0074-02761678-8060http://repositorio.ufpa.br/jspui/handle/2011/3310L-asparaginase production was investigated in the filamentous fungi Aspergillus tamarii and Aspergillus terreus. The fungi were cultivated in medium containing different nitrogen sources. A. terreus showed the highest L-asparaginase (activity) production level (58 U/L) when cultivated in a 2% proline medium. Both fungi presented the lowest level of L-asparaginase production in the presence of glutamine and urea as nitrogen sources. These results suggest that L-asparaginase production by of filamentous fungi is under nitrogen regulation.engAsparaginaseAspergillus tamariiAspergillus terreusFilamentos fungiProduction of L-asparaginase by filamentous fungiinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleSARQUIS, Maria Inez de MouraOLIVEIRA, Edna Maria MoraisSANTOS, Alberdan SilvaCOSTA, Gisela Lara dainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFPAinstname:Universidade Federal do Pará (UFPA)instacron:UFPAORIGINALArtigo_ProductionL-asparaginaseFilamentous.pdfArtigo_ProductionL-asparaginaseFilamentous.pdfapplication/pdf118857http://repositorio.ufpa.br/oai/bitstream/2011/3310/1/Artigo_ProductionL-asparaginaseFilamentous.pdf9743833e641f46da6cd7cfc08cece57eMD51CC-LICENSElicense_urllicense_urltext/plain; charset=utf-849http://repositorio.ufpa.br/oai/bitstream/2011/3310/2/license_urlfd26723f8d7edacdb29e3f03465c3b03MD52license_textlicense_texttext/html; charset=utf-80http://repositorio.ufpa.br/oai/bitstream/2011/3310/3/license_textd41d8cd98f00b204e9800998ecf8427eMD53license_rdflicense_rdfapplication/rdf+xml; charset=utf-80http://repositorio.ufpa.br/oai/bitstream/2011/3310/4/license_rdfd41d8cd98f00b204e9800998ecf8427eMD54LICENSElicense.txtlicense.txttext/plain; charset=utf-81996http://repositorio.ufpa.br/oai/bitstream/2011/3310/5/license.txt4b350777eea7a4b1ae7cd9a06fd687a1MD55TEXTArtigo_ProductionL-asparaginaseFilamentous.pdf.txtArtigo_ProductionL-asparaginaseFilamentous.pdf.txtExtracted texttext/plain17219http://repositorio.ufpa.br/oai/bitstream/2011/3310/6/Artigo_ProductionL-asparaginaseFilamentous.pdf.txt9e06f8d3bef6e77d20315ef0144c333aMD562011/33102018-01-09 14:43:07.552oai:repositorio.ufpa.br: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Repositório InstitucionalPUBhttp://repositorio.ufpa.br/oai/requestriufpabc@ufpa.bropendoar:21232018-01-09T17:43:07Repositório Institucional da UFPA - Universidade Federal do Pará (UFPA)false
dc.title.pt_BR.fl_str_mv Production of L-asparaginase by filamentous fungi
title Production of L-asparaginase by filamentous fungi
spellingShingle Production of L-asparaginase by filamentous fungi
Production of L-asparaginase by filamentous fungi
SARQUIS, Maria Inez de Moura
Asparaginase
Aspergillus tamarii
Aspergillus terreus
Filamentos fungi
SARQUIS, Maria Inez de Moura
Asparaginase
Aspergillus tamarii
Aspergillus terreus
Filamentos fungi
title_short Production of L-asparaginase by filamentous fungi
title_full Production of L-asparaginase by filamentous fungi
title_fullStr Production of L-asparaginase by filamentous fungi
Production of L-asparaginase by filamentous fungi
title_full_unstemmed Production of L-asparaginase by filamentous fungi
Production of L-asparaginase by filamentous fungi
title_sort Production of L-asparaginase by filamentous fungi
author SARQUIS, Maria Inez de Moura
author_facet SARQUIS, Maria Inez de Moura
SARQUIS, Maria Inez de Moura
OLIVEIRA, Edna Maria Morais
SANTOS, Alberdan Silva
COSTA, Gisela Lara da
OLIVEIRA, Edna Maria Morais
SANTOS, Alberdan Silva
COSTA, Gisela Lara da
author_role author
author2 OLIVEIRA, Edna Maria Morais
SANTOS, Alberdan Silva
COSTA, Gisela Lara da
author2_role author
author
author
dc.contributor.author.fl_str_mv SARQUIS, Maria Inez de Moura
OLIVEIRA, Edna Maria Morais
SANTOS, Alberdan Silva
COSTA, Gisela Lara da
dc.subject.por.fl_str_mv Asparaginase
Aspergillus tamarii
Aspergillus terreus
Filamentos fungi
topic Asparaginase
Aspergillus tamarii
Aspergillus terreus
Filamentos fungi
description L-asparaginase production was investigated in the filamentous fungi Aspergillus tamarii and Aspergillus terreus. The fungi were cultivated in medium containing different nitrogen sources. A. terreus showed the highest L-asparaginase (activity) production level (58 U/L) when cultivated in a 2% proline medium. Both fungi presented the lowest level of L-asparaginase production in the presence of glutamine and urea as nitrogen sources. These results suggest that L-asparaginase production by of filamentous fungi is under nitrogen regulation.
publishDate 2004
dc.date.issued.fl_str_mv 2004-08
dc.date.accessioned.fl_str_mv 2013-01-14T15:36:13Z
dc.date.available.fl_str_mv 2013-01-14T15:36:13Z
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dc.identifier.citation.fl_str_mv SARQUIS, Maria Inez de Moura, et al. Production of L-asparaginase by filamentous fungi. Memória do Instituto Oswaldo Cruz. Rio de Janeiro, v. 99, n.5, p. 489-492, ago. 2004. Disponível em: <http://www.scielo.br/pdf/mioc/v99n5/v99n5a05.pdf>. Acesso em: 10 dez. 2013. http://dx.doi.org/10.1590/S0074-02762004000500005.
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dc.identifier.issn.none.fl_str_mv 0074-0276
1678-8060
identifier_str_mv SARQUIS, Maria Inez de Moura, et al. Production of L-asparaginase by filamentous fungi. Memória do Instituto Oswaldo Cruz. Rio de Janeiro, v. 99, n.5, p. 489-492, ago. 2004. Disponível em: <http://www.scielo.br/pdf/mioc/v99n5/v99n5a05.pdf>. Acesso em: 10 dez. 2013. http://dx.doi.org/10.1590/S0074-02762004000500005.
0074-0276
1678-8060
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