Production of L-asparaginase by filamentous fungi

Detalhes bibliográficos
Autor(a) principal: SARQUIS, Maria Inez de Moura
Data de Publicação: 2004
Outros Autores: OLIVEIRA, Edna Maria Morais, SANTOS, Alberdan Silva, COSTA, Gisela Lara da
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFPA
Texto Completo: http://repositorio.ufpa.br/jspui/handle/2011/3310
Resumo: L-asparaginase production was investigated in the filamentous fungi Aspergillus tamarii and Aspergillus terreus. The fungi were cultivated in medium containing different nitrogen sources. A. terreus showed the highest L-asparaginase (activity) production level (58 U/L) when cultivated in a 2% proline medium. Both fungi presented the lowest level of L-asparaginase production in the presence of glutamine and urea as nitrogen sources. These results suggest that L-asparaginase production by of filamentous fungi is under nitrogen regulation.
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spelling 2013-01-14T15:36:13Z2013-01-14T15:36:13Z2004-08SARQUIS, Maria Inez de Moura, et al. Production of L-asparaginase by filamentous fungi. Memória do Instituto Oswaldo Cruz. Rio de Janeiro, v. 99, n.5, p. 489-492, ago. 2004. Disponível em: <http://www.scielo.br/pdf/mioc/v99n5/v99n5a05.pdf>. Acesso em: 10 dez. 2013. http://dx.doi.org/10.1590/S0074-02762004000500005.0074-02761678-8060http://repositorio.ufpa.br/jspui/handle/2011/3310L-asparaginase production was investigated in the filamentous fungi Aspergillus tamarii and Aspergillus terreus. The fungi were cultivated in medium containing different nitrogen sources. A. terreus showed the highest L-asparaginase (activity) production level (58 U/L) when cultivated in a 2% proline medium. Both fungi presented the lowest level of L-asparaginase production in the presence of glutamine and urea as nitrogen sources. These results suggest that L-asparaginase production by of filamentous fungi is under nitrogen regulation.engAsparaginaseAspergillus tamariiAspergillus terreusFilamentos fungiProduction of L-asparaginase by filamentous fungiinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleSARQUIS, Maria Inez de MouraOLIVEIRA, Edna Maria MoraisSANTOS, Alberdan SilvaCOSTA, Gisela Lara dainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFPAinstname:Universidade Federal do Pará (UFPA)instacron:UFPAORIGINALArtigo_ProductionL-asparaginaseFilamentous.pdfArtigo_ProductionL-asparaginaseFilamentous.pdfapplication/pdf118857http://repositorio.ufpa.br/oai/bitstream/2011/3310/1/Artigo_ProductionL-asparaginaseFilamentous.pdf9743833e641f46da6cd7cfc08cece57eMD51CC-LICENSElicense_urllicense_urltext/plain; charset=utf-849http://repositorio.ufpa.br/oai/bitstream/2011/3310/2/license_urlfd26723f8d7edacdb29e3f03465c3b03MD52license_textlicense_texttext/html; charset=utf-80http://repositorio.ufpa.br/oai/bitstream/2011/3310/3/license_textd41d8cd98f00b204e9800998ecf8427eMD53license_rdflicense_rdfapplication/rdf+xml; charset=utf-80http://repositorio.ufpa.br/oai/bitstream/2011/3310/4/license_rdfd41d8cd98f00b204e9800998ecf8427eMD54LICENSElicense.txtlicense.txttext/plain; charset=utf-81996http://repositorio.ufpa.br/oai/bitstream/2011/3310/5/license.txt4b350777eea7a4b1ae7cd9a06fd687a1MD55TEXTArtigo_ProductionL-asparaginaseFilamentous.pdf.txtArtigo_ProductionL-asparaginaseFilamentous.pdf.txtExtracted texttext/plain17219http://repositorio.ufpa.br/oai/bitstream/2011/3310/6/Artigo_ProductionL-asparaginaseFilamentous.pdf.txt9e06f8d3bef6e77d20315ef0144c333aMD562011/33102018-01-09 14:43:07.552oai:repositorio.ufpa.br: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Repositório InstitucionalPUBhttp://repositorio.ufpa.br/oai/requestriufpabc@ufpa.bropendoar:21232018-01-09T17:43:07Repositório Institucional da UFPA - Universidade Federal do Pará (UFPA)false
dc.title.pt_BR.fl_str_mv Production of L-asparaginase by filamentous fungi
title Production of L-asparaginase by filamentous fungi
spellingShingle Production of L-asparaginase by filamentous fungi
SARQUIS, Maria Inez de Moura
Asparaginase
Aspergillus tamarii
Aspergillus terreus
Filamentos fungi
title_short Production of L-asparaginase by filamentous fungi
title_full Production of L-asparaginase by filamentous fungi
title_fullStr Production of L-asparaginase by filamentous fungi
title_full_unstemmed Production of L-asparaginase by filamentous fungi
title_sort Production of L-asparaginase by filamentous fungi
author SARQUIS, Maria Inez de Moura
author_facet SARQUIS, Maria Inez de Moura
OLIVEIRA, Edna Maria Morais
SANTOS, Alberdan Silva
COSTA, Gisela Lara da
author_role author
author2 OLIVEIRA, Edna Maria Morais
SANTOS, Alberdan Silva
COSTA, Gisela Lara da
author2_role author
author
author
dc.contributor.author.fl_str_mv SARQUIS, Maria Inez de Moura
OLIVEIRA, Edna Maria Morais
SANTOS, Alberdan Silva
COSTA, Gisela Lara da
dc.subject.por.fl_str_mv Asparaginase
Aspergillus tamarii
Aspergillus terreus
Filamentos fungi
topic Asparaginase
Aspergillus tamarii
Aspergillus terreus
Filamentos fungi
description L-asparaginase production was investigated in the filamentous fungi Aspergillus tamarii and Aspergillus terreus. The fungi were cultivated in medium containing different nitrogen sources. A. terreus showed the highest L-asparaginase (activity) production level (58 U/L) when cultivated in a 2% proline medium. Both fungi presented the lowest level of L-asparaginase production in the presence of glutamine and urea as nitrogen sources. These results suggest that L-asparaginase production by of filamentous fungi is under nitrogen regulation.
publishDate 2004
dc.date.issued.fl_str_mv 2004-08
dc.date.accessioned.fl_str_mv 2013-01-14T15:36:13Z
dc.date.available.fl_str_mv 2013-01-14T15:36:13Z
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dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.citation.fl_str_mv SARQUIS, Maria Inez de Moura, et al. Production of L-asparaginase by filamentous fungi. Memória do Instituto Oswaldo Cruz. Rio de Janeiro, v. 99, n.5, p. 489-492, ago. 2004. Disponível em: <http://www.scielo.br/pdf/mioc/v99n5/v99n5a05.pdf>. Acesso em: 10 dez. 2013. http://dx.doi.org/10.1590/S0074-02762004000500005.
dc.identifier.uri.fl_str_mv http://repositorio.ufpa.br/jspui/handle/2011/3310
dc.identifier.issn.none.fl_str_mv 0074-0276
1678-8060
identifier_str_mv SARQUIS, Maria Inez de Moura, et al. Production of L-asparaginase by filamentous fungi. Memória do Instituto Oswaldo Cruz. Rio de Janeiro, v. 99, n.5, p. 489-492, ago. 2004. Disponível em: <http://www.scielo.br/pdf/mioc/v99n5/v99n5a05.pdf>. Acesso em: 10 dez. 2013. http://dx.doi.org/10.1590/S0074-02762004000500005.
0074-0276
1678-8060
url http://repositorio.ufpa.br/jspui/handle/2011/3310
dc.language.iso.fl_str_mv eng
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