Choice of toothpaste for the elderly: an in vitro study
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFPA |
Texto Completo: | http://repositorio.ufpa.br/jspui/handle/2011/8489 |
Resumo: | Hyposalivation and dental root exposure in the elderly are problems that require special oral care. In this context, the characteristics of certain toothpastes are of particular importance. Thus, the aim of this study was to evaluate the cytotoxicity and dentin wear caused by seven different toothpastes. For dentin wear analysis, 40 root dentin specimens were submitted to 20,000 brushing cycles with the different toothpastes and distilled water (control group-CG), using a brushing machine. Dentin surface loss (SL) was measured by contact profilometer. The cytotoxicity of each toothpaste was tested using cultured fibroblasts submitted to a cell-culture-conditioned medium. Fresh medium served as the control. Cell viability was assessed by MTT assay after 24 h of contact with the conditioned media. The data were analyzed statistically by ANOVA, followed by Tukey’s test (p < 0.05). The SL of the CG was minimal and significantly lower than that of the Oral B Pro Health (OBPH) group (p < 0.05). All other groups presented SL in between that of the CG and the Oral B Pro Health OBPH group, except for the Sensodyne (SEN) group, which presented SL similar to that of CG (p = 0.05). The SEN group presented a percentage of viable cells similar to that of CG: between 60-89%. All the other toothpastes showed high cytotoxicity, with cell viability less than 50% of the CG. Considering study limitations, we concluded that only one of the seven tested toothpastes exhibited the most desirable toothpaste characteristics for the worldwide growing elderly population (e.g. low cytotoxicity and low-abrasive potential) |
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2017-05-23T16:54:03Z2017-05-23T16:54:03Z2015-07RODRIGUES, Renata Duarte Souza et al. Choice of toothpaste for the elderly: an in vitro study. Brazilian Oral Research, São Paulo, v. 29, n. 1, p. 1-7, 2015. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242015000100288&lng=pt&nrm=iso>. Acesso em: 23 maio 2017. Epub 10-Jul-2015. <http://dx.doi.org/10.1590/1807-3107BOR-2015.vol29.0094>.1807-3107http://repositorio.ufpa.br/jspui/handle/2011/8489Hyposalivation and dental root exposure in the elderly are problems that require special oral care. In this context, the characteristics of certain toothpastes are of particular importance. Thus, the aim of this study was to evaluate the cytotoxicity and dentin wear caused by seven different toothpastes. For dentin wear analysis, 40 root dentin specimens were submitted to 20,000 brushing cycles with the different toothpastes and distilled water (control group-CG), using a brushing machine. Dentin surface loss (SL) was measured by contact profilometer. The cytotoxicity of each toothpaste was tested using cultured fibroblasts submitted to a cell-culture-conditioned medium. Fresh medium served as the control. Cell viability was assessed by MTT assay after 24 h of contact with the conditioned media. The data were analyzed statistically by ANOVA, followed by Tukey’s test (p < 0.05). The SL of the CG was minimal and significantly lower than that of the Oral B Pro Health (OBPH) group (p < 0.05). All other groups presented SL in between that of the CG and the Oral B Pro Health OBPH group, except for the Sensodyne (SEN) group, which presented SL similar to that of CG (p = 0.05). The SEN group presented a percentage of viable cells similar to that of CG: between 60-89%. All the other toothpastes showed high cytotoxicity, with cell viability less than 50% of the CG. Considering study limitations, we concluded that only one of the seven tested toothpastes exhibited the most desirable toothpaste characteristics for the worldwide growing elderly population (e.g. low cytotoxicity and low-abrasive potential)porUniversidade Federal do ParáUFPABrasilBrazilian Oral ResearchPasta de denteCuidados bucaisCitotoxicidadeDesgastes dos dentesDentinaChoice of toothpaste for the elderly: an in vitro studyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article29117RODRIGUES, Renata Duarte SouzaFERREIRA, Stella da SilvaCOUTO, Roberta Souza D'AlmeidaLACHOWSKI, Karina MonteleoneSOBRAL, Maria Ângela PitaMARQUES, Márcia Martinsinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFPAinstname:Universidade Federal do Pará (UFPA)instacron:UFPATEXTArtigo_ChoiceToothpasteElderly.pdf.txtArtigo_ChoiceToothpasteElderly.pdf.txtExtracted texttext/plain27718http://repositorio.ufpa.br/oai/bitstream/2011/8489/6/Artigo_ChoiceToothpasteElderly.pdf.txtda8f24af32ee476a6613c11d128b597fMD56ORIGINALArtigo_ChoiceToothpasteElderly.pdfArtigo_ChoiceToothpasteElderly.pdfapplication/pdf265939http://repositorio.ufpa.br/oai/bitstream/2011/8489/1/Artigo_ChoiceToothpasteElderly.pdf7384036f73578eed5d734b88751a2254MD51CC-LICENSElicense_urllicense_urltext/plain; charset=utf-849http://repositorio.ufpa.br/oai/bitstream/2011/8489/2/license_url4afdbb8c545fd630ea7db775da747b2fMD52license_textlicense_texttext/html; charset=utf-80http://repositorio.ufpa.br/oai/bitstream/2011/8489/3/license_textd41d8cd98f00b204e9800998ecf8427eMD53license_rdflicense_rdfapplication/rdf+xml; charset=utf-80http://repositorio.ufpa.br/oai/bitstream/2011/8489/4/license_rdfd41d8cd98f00b204e9800998ecf8427eMD54LICENSElicense.txtlicense.txttext/plain; charset=utf-81866http://repositorio.ufpa.br/oai/bitstream/2011/8489/5/license.txt43cd690d6a359e86c1fe3d5b7cba0c9bMD552011/84892018-02-26 13:24:08.616oai:repositorio.ufpa.br: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ório InstitucionalPUBhttp://repositorio.ufpa.br/oai/requestriufpabc@ufpa.bropendoar:21232018-02-26T16:24:08Repositório Institucional da UFPA - Universidade Federal do Pará (UFPA)false |
dc.title.pt_BR.fl_str_mv |
Choice of toothpaste for the elderly: an in vitro study |
title |
Choice of toothpaste for the elderly: an in vitro study |
spellingShingle |
Choice of toothpaste for the elderly: an in vitro study RODRIGUES, Renata Duarte Souza Pasta de dente Cuidados bucais Citotoxicidade Desgastes dos dentes Dentina |
title_short |
Choice of toothpaste for the elderly: an in vitro study |
title_full |
Choice of toothpaste for the elderly: an in vitro study |
title_fullStr |
Choice of toothpaste for the elderly: an in vitro study |
title_full_unstemmed |
Choice of toothpaste for the elderly: an in vitro study |
title_sort |
Choice of toothpaste for the elderly: an in vitro study |
author |
RODRIGUES, Renata Duarte Souza |
author_facet |
RODRIGUES, Renata Duarte Souza FERREIRA, Stella da Silva COUTO, Roberta Souza D'Almeida LACHOWSKI, Karina Monteleone SOBRAL, Maria Ângela Pita MARQUES, Márcia Martins |
author_role |
author |
author2 |
FERREIRA, Stella da Silva COUTO, Roberta Souza D'Almeida LACHOWSKI, Karina Monteleone SOBRAL, Maria Ângela Pita MARQUES, Márcia Martins |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
RODRIGUES, Renata Duarte Souza FERREIRA, Stella da Silva COUTO, Roberta Souza D'Almeida LACHOWSKI, Karina Monteleone SOBRAL, Maria Ângela Pita MARQUES, Márcia Martins |
dc.subject.por.fl_str_mv |
Pasta de dente Cuidados bucais Citotoxicidade Desgastes dos dentes Dentina |
topic |
Pasta de dente Cuidados bucais Citotoxicidade Desgastes dos dentes Dentina |
description |
Hyposalivation and dental root exposure in the elderly are problems that require special oral care. In this context, the characteristics of certain toothpastes are of particular importance. Thus, the aim of this study was to evaluate the cytotoxicity and dentin wear caused by seven different toothpastes. For dentin wear analysis, 40 root dentin specimens were submitted to 20,000 brushing cycles with the different toothpastes and distilled water (control group-CG), using a brushing machine. Dentin surface loss (SL) was measured by contact profilometer. The cytotoxicity of each toothpaste was tested using cultured fibroblasts submitted to a cell-culture-conditioned medium. Fresh medium served as the control. Cell viability was assessed by MTT assay after 24 h of contact with the conditioned media. The data were analyzed statistically by ANOVA, followed by Tukey’s test (p < 0.05). The SL of the CG was minimal and significantly lower than that of the Oral B Pro Health (OBPH) group (p < 0.05). All other groups presented SL in between that of the CG and the Oral B Pro Health OBPH group, except for the Sensodyne (SEN) group, which presented SL similar to that of CG (p = 0.05). The SEN group presented a percentage of viable cells similar to that of CG: between 60-89%. All the other toothpastes showed high cytotoxicity, with cell viability less than 50% of the CG. Considering study limitations, we concluded that only one of the seven tested toothpastes exhibited the most desirable toothpaste characteristics for the worldwide growing elderly population (e.g. low cytotoxicity and low-abrasive potential) |
publishDate |
2015 |
dc.date.issued.fl_str_mv |
2015-07 |
dc.date.accessioned.fl_str_mv |
2017-05-23T16:54:03Z |
dc.date.available.fl_str_mv |
2017-05-23T16:54:03Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
RODRIGUES, Renata Duarte Souza et al. Choice of toothpaste for the elderly: an in vitro study. Brazilian Oral Research, São Paulo, v. 29, n. 1, p. 1-7, 2015. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242015000100288&lng=pt&nrm=iso>. Acesso em: 23 maio 2017. Epub 10-Jul-2015. <http://dx.doi.org/10.1590/1807-3107BOR-2015.vol29.0094>. |
dc.identifier.uri.fl_str_mv |
http://repositorio.ufpa.br/jspui/handle/2011/8489 |
dc.identifier.issn.pt_BR.fl_str_mv |
1807-3107 |
identifier_str_mv |
RODRIGUES, Renata Duarte Souza et al. Choice of toothpaste for the elderly: an in vitro study. Brazilian Oral Research, São Paulo, v. 29, n. 1, p. 1-7, 2015. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242015000100288&lng=pt&nrm=iso>. Acesso em: 23 maio 2017. Epub 10-Jul-2015. <http://dx.doi.org/10.1590/1807-3107BOR-2015.vol29.0094>. 1807-3107 |
url |
http://repositorio.ufpa.br/jspui/handle/2011/8489 |
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por |
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por |
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Brazilian Oral Research |
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openAccess |
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Universidade Federal do Pará |
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UFPA |
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Brasil |
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Universidade Federal do Pará |
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