Mercury toxicity in the Amazon: contrast sensitivity and color discrimination of subjects exposed to mercury
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Outros Autores: | , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFPA |
Texto Completo: | http://www.repositorio.ufpa.br:8080/jspui/handle/2011/2417 |
Resumo: | We measured visual performance in achromatic and chromatic spatial tasks of mercury-exposed subjects and compared the results with norms obtained from healthy individuals of similar age. Data were obtained for a group of 28 mercury-exposed subjects, comprising 20 Amazonian gold miners, 2 inhabitants of Amazonian riverside communities, and 6 laboratory technicians, who asked for medical care. Statistical norms were generated by testing healthy control subjects divided into three age groups. The performance of a substantial proportion of the mercury-exposed subjects was below the norms in all of these tasks. Eleven of 20 subjects (55%) performed below the norms in the achromatic contrast sensitivity task. The mercury-exposed subjects also had lower red-green contrast sensitivity deficits at all tested spatial frequencies (9/11 subjects; 81%). Three gold miners and 1 riverine (4/19 subjects, 21%) performed worse than normal subjects making more mistakes in the color arrangement test. Five of 10 subjects tested (50%), comprising 2 gold miners, 2 technicians, and 1 riverine, performed worse than normal in the color discrimination test, having areas of one or more MacAdam ellipse larger than normal subjects and high color discrimination thresholds at least in one color locus. These data indicate that psychophysical assessment can be used to quantify the degree of visual impairment of mercury-exposed subjects. They also suggest that some spatial tests such as the measurement of red-green chromatic contrast are sufficiently sensitive to detect visual dysfunction caused by mercury toxicity. |
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2011-12-07T13:58:46Z2011-12-07T13:58:46Z2007-03RODRIGUES, A.R. et al. Mercury toxicity in the Amazon: contrast sensitivity and color discrimination of subjects exposed to mercury. Brazilian Journal of Medical and Biological Research, Ribeirão Preto, v. 40, n. 3, p. 415-424, mar. 2007. Disponível em: <http://www.scielo.br/pdf/bjmbr/v40n3/6241.pdf> Acesso em: 07 dez. 2011. <http://dx.doi.org/10.1590/S0100-879X2007000300018>.1414-431Xhttp://www.repositorio.ufpa.br:8080/jspui/handle/2011/2417We measured visual performance in achromatic and chromatic spatial tasks of mercury-exposed subjects and compared the results with norms obtained from healthy individuals of similar age. Data were obtained for a group of 28 mercury-exposed subjects, comprising 20 Amazonian gold miners, 2 inhabitants of Amazonian riverside communities, and 6 laboratory technicians, who asked for medical care. Statistical norms were generated by testing healthy control subjects divided into three age groups. The performance of a substantial proportion of the mercury-exposed subjects was below the norms in all of these tasks. Eleven of 20 subjects (55%) performed below the norms in the achromatic contrast sensitivity task. The mercury-exposed subjects also had lower red-green contrast sensitivity deficits at all tested spatial frequencies (9/11 subjects; 81%). Three gold miners and 1 riverine (4/19 subjects, 21%) performed worse than normal subjects making more mistakes in the color arrangement test. Five of 10 subjects tested (50%), comprising 2 gold miners, 2 technicians, and 1 riverine, performed worse than normal in the color discrimination test, having areas of one or more MacAdam ellipse larger than normal subjects and high color discrimination thresholds at least in one color locus. These data indicate that psychophysical assessment can be used to quantify the degree of visual impairment of mercury-exposed subjects. They also suggest that some spatial tests such as the measurement of red-green chromatic contrast are sufficiently sensitive to detect visual dysfunction caused by mercury toxicity.engMercúrioExposição (Poluição)MercúrioPopulação ribeirinhaToxicologiaSensibilidade de contraste (Visão)Amazônia brasileiraMercury toxicity in the Amazon: contrast sensitivity and color discrimination of subjects exposed to mercuryinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleRODRIGUES, Anderson RaiolSOUZA, Cleidson Ronald Botelho deBRAGA, Alexandre MeloRODRIGUES, Paulo Sergio SilvaSILVEIRA, Antonio TobiasDAMIN, Enira Teresinha BraghirolliCÔRTES, Maria Izabel TentesCASTRO, Antonio José de OliveiraMELLO, Guilherme ArantesVIEIRA, José Luiz FernandesPINHEIRO, Maria da Conceição NascimentoVENTURA, Dora Selma FixSILVEIRA, Luiz Carlos de Limainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFPAinstname:Universidade Federal do Pará (UFPA)instacron:UFPAORIGINALArtigo_MercuryToxicityAmazon.pdfArtigo_MercuryToxicityAmazon.pdfapplication/pdf496518http://repositorio.ufpa.br/oai/bitstream/2011/2417/1/Artigo_MercuryToxicityAmazon.pdf80689bf2d60ed82bbb86b45efbe11148MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://repositorio.ufpa.br/oai/bitstream/2011/2417/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-823599http://repositorio.ufpa.br/oai/bitstream/2011/2417/3/license_rdf9e2b7f6edbd693264102b96ece20428aMD53license_textlicense_texttext/html; charset=utf-80http://repositorio.ufpa.br/oai/bitstream/2011/2417/4/license_textd41d8cd98f00b204e9800998ecf8427eMD54license_urllicense_urltext/plain; charset=utf-849http://repositorio.ufpa.br/oai/bitstream/2011/2417/5/license_urlfd26723f8d7edacdb29e3f03465c3b03MD55TEXTArtigo_MercuryToxicityAmazon.pdf.txtArtigo_MercuryToxicityAmazon.pdf.txtExtracted texttext/plain36653http://repositorio.ufpa.br/oai/bitstream/2011/2417/6/Artigo_MercuryToxicityAmazon.pdf.txtd675a662a4d2ca74d832c2b2abc8de6bMD562011/24172019-05-23 08:11:44.869oai:repositorio.ufpa.br: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Repositório InstitucionalPUBhttp://repositorio.ufpa.br/oai/requestriufpabc@ufpa.bropendoar:21232019-05-23T11:11:44Repositório Institucional da UFPA - Universidade Federal do Pará (UFPA)false |
dc.title.pt_BR.fl_str_mv |
Mercury toxicity in the Amazon: contrast sensitivity and color discrimination of subjects exposed to mercury |
title |
Mercury toxicity in the Amazon: contrast sensitivity and color discrimination of subjects exposed to mercury |
spellingShingle |
Mercury toxicity in the Amazon: contrast sensitivity and color discrimination of subjects exposed to mercury RODRIGUES, Anderson Raiol Mercúrio Exposição (Poluição) Mercúrio População ribeirinha Toxicologia Sensibilidade de contraste (Visão) Amazônia brasileira |
title_short |
Mercury toxicity in the Amazon: contrast sensitivity and color discrimination of subjects exposed to mercury |
title_full |
Mercury toxicity in the Amazon: contrast sensitivity and color discrimination of subjects exposed to mercury |
title_fullStr |
Mercury toxicity in the Amazon: contrast sensitivity and color discrimination of subjects exposed to mercury |
title_full_unstemmed |
Mercury toxicity in the Amazon: contrast sensitivity and color discrimination of subjects exposed to mercury |
title_sort |
Mercury toxicity in the Amazon: contrast sensitivity and color discrimination of subjects exposed to mercury |
author |
RODRIGUES, Anderson Raiol |
author_facet |
RODRIGUES, Anderson Raiol SOUZA, Cleidson Ronald Botelho de BRAGA, Alexandre Melo RODRIGUES, Paulo Sergio Silva SILVEIRA, Antonio Tobias DAMIN, Enira Teresinha Braghirolli CÔRTES, Maria Izabel Tentes CASTRO, Antonio José de Oliveira MELLO, Guilherme Arantes VIEIRA, José Luiz Fernandes PINHEIRO, Maria da Conceição Nascimento VENTURA, Dora Selma Fix SILVEIRA, Luiz Carlos de Lima |
author_role |
author |
author2 |
SOUZA, Cleidson Ronald Botelho de BRAGA, Alexandre Melo RODRIGUES, Paulo Sergio Silva SILVEIRA, Antonio Tobias DAMIN, Enira Teresinha Braghirolli CÔRTES, Maria Izabel Tentes CASTRO, Antonio José de Oliveira MELLO, Guilherme Arantes VIEIRA, José Luiz Fernandes PINHEIRO, Maria da Conceição Nascimento VENTURA, Dora Selma Fix SILVEIRA, Luiz Carlos de Lima |
author2_role |
author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
RODRIGUES, Anderson Raiol SOUZA, Cleidson Ronald Botelho de BRAGA, Alexandre Melo RODRIGUES, Paulo Sergio Silva SILVEIRA, Antonio Tobias DAMIN, Enira Teresinha Braghirolli CÔRTES, Maria Izabel Tentes CASTRO, Antonio José de Oliveira MELLO, Guilherme Arantes VIEIRA, José Luiz Fernandes PINHEIRO, Maria da Conceição Nascimento VENTURA, Dora Selma Fix SILVEIRA, Luiz Carlos de Lima |
dc.subject.por.fl_str_mv |
Mercúrio Exposição (Poluição) Mercúrio População ribeirinha Toxicologia Sensibilidade de contraste (Visão) Amazônia brasileira |
topic |
Mercúrio Exposição (Poluição) Mercúrio População ribeirinha Toxicologia Sensibilidade de contraste (Visão) Amazônia brasileira |
description |
We measured visual performance in achromatic and chromatic spatial tasks of mercury-exposed subjects and compared the results with norms obtained from healthy individuals of similar age. Data were obtained for a group of 28 mercury-exposed subjects, comprising 20 Amazonian gold miners, 2 inhabitants of Amazonian riverside communities, and 6 laboratory technicians, who asked for medical care. Statistical norms were generated by testing healthy control subjects divided into three age groups. The performance of a substantial proportion of the mercury-exposed subjects was below the norms in all of these tasks. Eleven of 20 subjects (55%) performed below the norms in the achromatic contrast sensitivity task. The mercury-exposed subjects also had lower red-green contrast sensitivity deficits at all tested spatial frequencies (9/11 subjects; 81%). Three gold miners and 1 riverine (4/19 subjects, 21%) performed worse than normal subjects making more mistakes in the color arrangement test. Five of 10 subjects tested (50%), comprising 2 gold miners, 2 technicians, and 1 riverine, performed worse than normal in the color discrimination test, having areas of one or more MacAdam ellipse larger than normal subjects and high color discrimination thresholds at least in one color locus. These data indicate that psychophysical assessment can be used to quantify the degree of visual impairment of mercury-exposed subjects. They also suggest that some spatial tests such as the measurement of red-green chromatic contrast are sufficiently sensitive to detect visual dysfunction caused by mercury toxicity. |
publishDate |
2007 |
dc.date.issued.fl_str_mv |
2007-03 |
dc.date.accessioned.fl_str_mv |
2011-12-07T13:58:46Z |
dc.date.available.fl_str_mv |
2011-12-07T13:58:46Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
RODRIGUES, A.R. et al. Mercury toxicity in the Amazon: contrast sensitivity and color discrimination of subjects exposed to mercury. Brazilian Journal of Medical and Biological Research, Ribeirão Preto, v. 40, n. 3, p. 415-424, mar. 2007. Disponível em: <http://www.scielo.br/pdf/bjmbr/v40n3/6241.pdf> Acesso em: 07 dez. 2011. <http://dx.doi.org/10.1590/S0100-879X2007000300018>. |
dc.identifier.uri.fl_str_mv |
http://www.repositorio.ufpa.br:8080/jspui/handle/2011/2417 |
dc.identifier.issn.none.fl_str_mv |
1414-431X |
identifier_str_mv |
RODRIGUES, A.R. et al. Mercury toxicity in the Amazon: contrast sensitivity and color discrimination of subjects exposed to mercury. Brazilian Journal of Medical and Biological Research, Ribeirão Preto, v. 40, n. 3, p. 415-424, mar. 2007. Disponível em: <http://www.scielo.br/pdf/bjmbr/v40n3/6241.pdf> Acesso em: 07 dez. 2011. <http://dx.doi.org/10.1590/S0100-879X2007000300018>. 1414-431X |
url |
http://www.repositorio.ufpa.br:8080/jspui/handle/2011/2417 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
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reponame:Repositório Institucional da UFPA instname:Universidade Federal do Pará (UFPA) instacron:UFPA |
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Universidade Federal do Pará (UFPA) |
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UFPA |
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UFPA |
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Repositório Institucional da UFPA |
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Repositório Institucional da UFPA |
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