Chlamydia trachomatis serotype A infections in the Amazon region of Brazil: prevalence, entry and dissemination
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFPA |
Texto Completo: | http://repositorio.ufpa.br/jspui/handle/2011/7705 |
Resumo: | INTRODUCTION: Chlamydia infection is associated with debilitating human diseases including trachoma, pneumonia, coronary heart disease and urogenital diseases. Serotypes of C. trachomatis show a fair correlation with the group of diseases they cause, and their distribution follows a well-described geographic pattern. Serotype A, a trachoma-associated strain, is known for its limited dissemination in the Middle East and Northern Africa. However, knowledge on the spread of bacteria from the genus Chlamydia as well as the distribution of serotypes in Brazil is quite limited. METHODS: Blood samples of 1,710 individuals from ten human population groups in the Amazon region of Brazil were examined for antibodies to Chlamydia using indirect immunofluorescence and microimmunofluorescence assays. RESULTS: The prevalence of antibodies to Chlamydia ranged from 23.9% (Wayana-Apalai) to 90.7% (Awa-Guaja) with a mean prevalence of 50.2%. Seroreactivity was detected to C. pneumoniae and to all serotypes of C. trachomatis tested; furthermore, we report clear evidence of the as-yet-undescribed occurrence of serotype A of C. trachomatis. CONCLUSIONS: Specific seroreactivity not only accounts for the large extent of dissemination of C. trachomatis in the Amazon region of Brazil but also shows an expanded area of occurrence of serotype A outside the epidemiological settings previously described. Furthermore, these data suggest possible routes of Chlamydia introduction into the Amazon region from the massive human migration that occurred during the 1,700s. |
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2017-02-15T16:51:35Z2017-02-15T16:51:35Z2015-04ISHAK, Marluísa de Oliveira Guimarães et al. Chlamydia trachomatis serotype A infections in the Amazon region of Brazil: prevalence, entry and dissemination. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 48, n. 2, p. 170-174, abr. 2015. Disponível em: <http://www.scielo.br/pdf/rsbmt/v48n2/0037-8682-rsbmt-48-02-00170.pdf>. Acesso em: 15 fev. 2017. <http://dx.doi.org/10.1590/0037-8682-0038-2015>.0037-8682http://repositorio.ufpa.br/jspui/handle/2011/7705INTRODUCTION: Chlamydia infection is associated with debilitating human diseases including trachoma, pneumonia, coronary heart disease and urogenital diseases. Serotypes of C. trachomatis show a fair correlation with the group of diseases they cause, and their distribution follows a well-described geographic pattern. Serotype A, a trachoma-associated strain, is known for its limited dissemination in the Middle East and Northern Africa. However, knowledge on the spread of bacteria from the genus Chlamydia as well as the distribution of serotypes in Brazil is quite limited. METHODS: Blood samples of 1,710 individuals from ten human population groups in the Amazon region of Brazil were examined for antibodies to Chlamydia using indirect immunofluorescence and microimmunofluorescence assays. RESULTS: The prevalence of antibodies to Chlamydia ranged from 23.9% (Wayana-Apalai) to 90.7% (Awa-Guaja) with a mean prevalence of 50.2%. Seroreactivity was detected to C. pneumoniae and to all serotypes of C. trachomatis tested; furthermore, we report clear evidence of the as-yet-undescribed occurrence of serotype A of C. trachomatis. CONCLUSIONS: Specific seroreactivity not only accounts for the large extent of dissemination of C. trachomatis in the Amazon region of Brazil but also shows an expanded area of occurrence of serotype A outside the epidemiological settings previously described. Furthermore, these data suggest possible routes of Chlamydia introduction into the Amazon region from the massive human migration that occurred during the 1,700s.porUniversidade Federal do ParáUFPABrasilRevista da Sociedade Brasileira de Medicina TropicalInfecções por ChlamydiaBactériasSorotipo AEpidemiologiaAmazônia brasileiraChlamydia trachomatis serotype A infections in the Amazon region of Brazil: prevalence, entry and disseminationinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article482170174ISHAK, Marluísa de Oliveira GuimarãesCOSTA, Maurimélia Mesquita daALMEIDA, Núbia Caroline Costa deSANTIAGO, Angélica MenezesBRITO, William Botelho deVALLINOTO, Antonio Carlos RosárioAZEVEDO, Vânia NakauthISHAK, Ricardoinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFPAinstname:Universidade Federal do Pará (UFPA)instacron:UFPAORIGINALArtigo_ChlamydiaTrachomatisSerotype.pdfArtigo_ChlamydiaTrachomatisSerotype.pdfapplication/pdf794912http://repositorio.ufpa.br/oai/bitstream/2011/7705/1/Artigo_ChlamydiaTrachomatisSerotype.pdf20c03809724120885b2d9356d1fb985cMD51CC-LICENSElicense_urllicense_urltext/plain; charset=utf-849http://repositorio.ufpa.br/oai/bitstream/2011/7705/2/license_url4afdbb8c545fd630ea7db775da747b2fMD52license_textlicense_texttext/html; charset=utf-80http://repositorio.ufpa.br/oai/bitstream/2011/7705/3/license_textd41d8cd98f00b204e9800998ecf8427eMD53license_rdflicense_rdfapplication/rdf+xml; charset=utf-80http://repositorio.ufpa.br/oai/bitstream/2011/7705/4/license_rdfd41d8cd98f00b204e9800998ecf8427eMD54LICENSElicense.txtlicense.txttext/plain; charset=utf-81866http://repositorio.ufpa.br/oai/bitstream/2011/7705/5/license.txt43cd690d6a359e86c1fe3d5b7cba0c9bMD55TEXTArtigo_ChlamydiaTrachomatisSerotype.pdf.txtArtigo_ChlamydiaTrachomatisSerotype.pdf.txtExtracted texttext/plain24377http://repositorio.ufpa.br/oai/bitstream/2011/7705/6/Artigo_ChlamydiaTrachomatisSerotype.pdf.txt59e2d69cd82c57ed0f4d311384b714b0MD562011/77052019-05-23 08:11:49.399oai:repositorio.ufpa.br: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ório InstitucionalPUBhttp://repositorio.ufpa.br/oai/requestriufpabc@ufpa.bropendoar:21232019-05-23T11:11:49Repositório Institucional da UFPA - Universidade Federal do Pará (UFPA)false |
dc.title.pt_BR.fl_str_mv |
Chlamydia trachomatis serotype A infections in the Amazon region of Brazil: prevalence, entry and dissemination |
title |
Chlamydia trachomatis serotype A infections in the Amazon region of Brazil: prevalence, entry and dissemination |
spellingShingle |
Chlamydia trachomatis serotype A infections in the Amazon region of Brazil: prevalence, entry and dissemination ISHAK, Marluísa de Oliveira Guimarães Infecções por Chlamydia Bactérias Sorotipo A Epidemiologia Amazônia brasileira |
title_short |
Chlamydia trachomatis serotype A infections in the Amazon region of Brazil: prevalence, entry and dissemination |
title_full |
Chlamydia trachomatis serotype A infections in the Amazon region of Brazil: prevalence, entry and dissemination |
title_fullStr |
Chlamydia trachomatis serotype A infections in the Amazon region of Brazil: prevalence, entry and dissemination |
title_full_unstemmed |
Chlamydia trachomatis serotype A infections in the Amazon region of Brazil: prevalence, entry and dissemination |
title_sort |
Chlamydia trachomatis serotype A infections in the Amazon region of Brazil: prevalence, entry and dissemination |
author |
ISHAK, Marluísa de Oliveira Guimarães |
author_facet |
ISHAK, Marluísa de Oliveira Guimarães COSTA, Maurimélia Mesquita da ALMEIDA, Núbia Caroline Costa de SANTIAGO, Angélica Menezes BRITO, William Botelho de VALLINOTO, Antonio Carlos Rosário AZEVEDO, Vânia Nakauth ISHAK, Ricardo |
author_role |
author |
author2 |
COSTA, Maurimélia Mesquita da ALMEIDA, Núbia Caroline Costa de SANTIAGO, Angélica Menezes BRITO, William Botelho de VALLINOTO, Antonio Carlos Rosário AZEVEDO, Vânia Nakauth ISHAK, Ricardo |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
ISHAK, Marluísa de Oliveira Guimarães COSTA, Maurimélia Mesquita da ALMEIDA, Núbia Caroline Costa de SANTIAGO, Angélica Menezes BRITO, William Botelho de VALLINOTO, Antonio Carlos Rosário AZEVEDO, Vânia Nakauth ISHAK, Ricardo |
dc.subject.por.fl_str_mv |
Infecções por Chlamydia Bactérias Sorotipo A Epidemiologia Amazônia brasileira |
topic |
Infecções por Chlamydia Bactérias Sorotipo A Epidemiologia Amazônia brasileira |
description |
INTRODUCTION: Chlamydia infection is associated with debilitating human diseases including trachoma, pneumonia, coronary heart disease and urogenital diseases. Serotypes of C. trachomatis show a fair correlation with the group of diseases they cause, and their distribution follows a well-described geographic pattern. Serotype A, a trachoma-associated strain, is known for its limited dissemination in the Middle East and Northern Africa. However, knowledge on the spread of bacteria from the genus Chlamydia as well as the distribution of serotypes in Brazil is quite limited. METHODS: Blood samples of 1,710 individuals from ten human population groups in the Amazon region of Brazil were examined for antibodies to Chlamydia using indirect immunofluorescence and microimmunofluorescence assays. RESULTS: The prevalence of antibodies to Chlamydia ranged from 23.9% (Wayana-Apalai) to 90.7% (Awa-Guaja) with a mean prevalence of 50.2%. Seroreactivity was detected to C. pneumoniae and to all serotypes of C. trachomatis tested; furthermore, we report clear evidence of the as-yet-undescribed occurrence of serotype A of C. trachomatis. CONCLUSIONS: Specific seroreactivity not only accounts for the large extent of dissemination of C. trachomatis in the Amazon region of Brazil but also shows an expanded area of occurrence of serotype A outside the epidemiological settings previously described. Furthermore, these data suggest possible routes of Chlamydia introduction into the Amazon region from the massive human migration that occurred during the 1,700s. |
publishDate |
2015 |
dc.date.issued.fl_str_mv |
2015-04 |
dc.date.accessioned.fl_str_mv |
2017-02-15T16:51:35Z |
dc.date.available.fl_str_mv |
2017-02-15T16:51:35Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
ISHAK, Marluísa de Oliveira Guimarães et al. Chlamydia trachomatis serotype A infections in the Amazon region of Brazil: prevalence, entry and dissemination. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 48, n. 2, p. 170-174, abr. 2015. Disponível em: <http://www.scielo.br/pdf/rsbmt/v48n2/0037-8682-rsbmt-48-02-00170.pdf>. Acesso em: 15 fev. 2017. <http://dx.doi.org/10.1590/0037-8682-0038-2015>. |
dc.identifier.uri.fl_str_mv |
http://repositorio.ufpa.br/jspui/handle/2011/7705 |
dc.identifier.issn.pt_BR.fl_str_mv |
0037-8682 |
identifier_str_mv |
ISHAK, Marluísa de Oliveira Guimarães et al. Chlamydia trachomatis serotype A infections in the Amazon region of Brazil: prevalence, entry and dissemination. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 48, n. 2, p. 170-174, abr. 2015. Disponível em: <http://www.scielo.br/pdf/rsbmt/v48n2/0037-8682-rsbmt-48-02-00170.pdf>. Acesso em: 15 fev. 2017. <http://dx.doi.org/10.1590/0037-8682-0038-2015>. 0037-8682 |
url |
http://repositorio.ufpa.br/jspui/handle/2011/7705 |
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Universidade Federal do Pará |
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