Does plasma ANP participate in natriuresis induced by a-MSH?
Autor(a) principal: | |
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Data de Publicação: | 1997 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFPA |
Texto Completo: | http://repositorio.ufpa.br/jspui/handle/2011/3290 |
Resumo: | -Melanocyte-stimulating hormone (-MSH; 0.6 and 3 nmol) microinjected into the anteroventral region of the third ventricle (AV3V) induced a significant increase in diuresis without modifying natriuresis or kaliuresis. Intraperitoneal (ip) injection of -MSH (3 and 9.6 nmol) induced a significant increase in urinary sodium, potassium and water excretion. Intraperitoneal (3 and 4.8 nmol) or iv (3 and 9.6 nmol) administration of -MSH did not induce any significant changes in plasma atrial natriuretic peptide (ANP), suggesting that the natriuresis, kaliuresis and diuresis induced by the systemic action of -MSH can be dissociated from the increase in plasma ANP. These preliminary results suggest that -MSH may be involved in a -MSHindependent mechanism of regulation of hydromineral metabolism. |
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2012-12-20T14:35:42Z2012-12-20T14:35:42Z1997-04PICANÇO-DINIZ, D.L.W. et al. Does plasma ANP participate in natriuresis induced by a-MSH? Brazilian Journal of Medical and Biological Research, Ribeirão Preto, v. 30, n. 4, p. 459-463, abr. 1997. Disponível em: <http://www.scielo.br/pdf/bjmbr/v30n4/2786C.pdf>. Acesso em: 11 dez. 2012. <http://dx.doi.org/10.1590/S0100-879X1997000400005>.1414-431Xhttp://repositorio.ufpa.br/jspui/handle/2011/3290-Melanocyte-stimulating hormone (-MSH; 0.6 and 3 nmol) microinjected into the anteroventral region of the third ventricle (AV3V) induced a significant increase in diuresis without modifying natriuresis or kaliuresis. Intraperitoneal (ip) injection of -MSH (3 and 9.6 nmol) induced a significant increase in urinary sodium, potassium and water excretion. Intraperitoneal (3 and 4.8 nmol) or iv (3 and 9.6 nmol) administration of -MSH did not induce any significant changes in plasma atrial natriuretic peptide (ANP), suggesting that the natriuresis, kaliuresis and diuresis induced by the systemic action of -MSH can be dissociated from the increase in plasma ANP. These preliminary results suggest that -MSH may be involved in a -MSHindependent mechanism of regulation of hydromineral metabolism.engHormônio estimulador de melanócitoFator natriurético atrialNatriureseCaliuresesDiurelisDoes plasma ANP participate in natriuresis induced by a-MSH?info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleDINIZ, Domingos Luiz Wanderley PicançoOLIVEIRA, Gustavo Ribeiro deFAVARETTO, Ana Lucia ViannaGUTKOWSKA, J.MCCANN, S.M.RODRIGUES, José Antunesinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFPAinstname:Universidade Federal do Pará (UFPA)instacron:UFPAORIGINALArtigo_DoesPlasmaANP.pdfArtigo_DoesPlasmaANP.pdfapplication/pdf238819http://repositorio.ufpa.br/oai/bitstream/2011/3290/1/Artigo_DoesPlasmaANP.pdf9d142c21d1b8f53c00d11d22c0820a69MD51CC-LICENSElicense_urllicense_urltext/plain; charset=utf-849http://repositorio.ufpa.br/oai/bitstream/2011/3290/2/license_urlfd26723f8d7edacdb29e3f03465c3b03MD52license_textlicense_texttext/html; charset=utf-80http://repositorio.ufpa.br/oai/bitstream/2011/3290/3/license_textd41d8cd98f00b204e9800998ecf8427eMD53license_rdflicense_rdfapplication/rdf+xml; charset=utf-823599http://repositorio.ufpa.br/oai/bitstream/2011/3290/4/license_rdf9e2b7f6edbd693264102b96ece20428aMD54LICENSElicense.txtlicense.txttext/plain; charset=utf-82012http://repositorio.ufpa.br/oai/bitstream/2011/3290/5/license.txtcd821bd92717df12c0e7cf48f7bc1694MD55TEXTArtigo_DoesPlasmaANP.pdf.txtArtigo_DoesPlasmaANP.pdf.txtExtracted texttext/plain17252http://repositorio.ufpa.br/oai/bitstream/2011/3290/6/Artigo_DoesPlasmaANP.pdf.txtfcc331dd8de4cd645dbedaa5b129b3b4MD562011/32902017-10-16 12:57:30.198oai:repositorio.ufpa.br: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Repositório InstitucionalPUBhttp://repositorio.ufpa.br/oai/requestriufpabc@ufpa.bropendoar:21232017-10-16T15:57:30Repositório Institucional da UFPA - Universidade Federal do Pará (UFPA)false |
dc.title.pt_BR.fl_str_mv |
Does plasma ANP participate in natriuresis induced by a-MSH? |
title |
Does plasma ANP participate in natriuresis induced by a-MSH? |
spellingShingle |
Does plasma ANP participate in natriuresis induced by a-MSH? DINIZ, Domingos Luiz Wanderley Picanço Hormônio estimulador de melanócito Fator natriurético atrial Natriurese Caliureses Diurelis |
title_short |
Does plasma ANP participate in natriuresis induced by a-MSH? |
title_full |
Does plasma ANP participate in natriuresis induced by a-MSH? |
title_fullStr |
Does plasma ANP participate in natriuresis induced by a-MSH? |
title_full_unstemmed |
Does plasma ANP participate in natriuresis induced by a-MSH? |
title_sort |
Does plasma ANP participate in natriuresis induced by a-MSH? |
author |
DINIZ, Domingos Luiz Wanderley Picanço |
author_facet |
DINIZ, Domingos Luiz Wanderley Picanço OLIVEIRA, Gustavo Ribeiro de FAVARETTO, Ana Lucia Vianna GUTKOWSKA, J. MCCANN, S.M. RODRIGUES, José Antunes |
author_role |
author |
author2 |
OLIVEIRA, Gustavo Ribeiro de FAVARETTO, Ana Lucia Vianna GUTKOWSKA, J. MCCANN, S.M. RODRIGUES, José Antunes |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
DINIZ, Domingos Luiz Wanderley Picanço OLIVEIRA, Gustavo Ribeiro de FAVARETTO, Ana Lucia Vianna GUTKOWSKA, J. MCCANN, S.M. RODRIGUES, José Antunes |
dc.subject.por.fl_str_mv |
Hormônio estimulador de melanócito Fator natriurético atrial Natriurese Caliureses Diurelis |
topic |
Hormônio estimulador de melanócito Fator natriurético atrial Natriurese Caliureses Diurelis |
description |
-Melanocyte-stimulating hormone (-MSH; 0.6 and 3 nmol) microinjected into the anteroventral region of the third ventricle (AV3V) induced a significant increase in diuresis without modifying natriuresis or kaliuresis. Intraperitoneal (ip) injection of -MSH (3 and 9.6 nmol) induced a significant increase in urinary sodium, potassium and water excretion. Intraperitoneal (3 and 4.8 nmol) or iv (3 and 9.6 nmol) administration of -MSH did not induce any significant changes in plasma atrial natriuretic peptide (ANP), suggesting that the natriuresis, kaliuresis and diuresis induced by the systemic action of -MSH can be dissociated from the increase in plasma ANP. These preliminary results suggest that -MSH may be involved in a -MSHindependent mechanism of regulation of hydromineral metabolism. |
publishDate |
1997 |
dc.date.issued.fl_str_mv |
1997-04 |
dc.date.accessioned.fl_str_mv |
2012-12-20T14:35:42Z |
dc.date.available.fl_str_mv |
2012-12-20T14:35:42Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
PICANÇO-DINIZ, D.L.W. et al. Does plasma ANP participate in natriuresis induced by a-MSH? Brazilian Journal of Medical and Biological Research, Ribeirão Preto, v. 30, n. 4, p. 459-463, abr. 1997. Disponível em: <http://www.scielo.br/pdf/bjmbr/v30n4/2786C.pdf>. Acesso em: 11 dez. 2012. <http://dx.doi.org/10.1590/S0100-879X1997000400005>. |
dc.identifier.uri.fl_str_mv |
http://repositorio.ufpa.br/jspui/handle/2011/3290 |
dc.identifier.issn.none.fl_str_mv |
1414-431X |
identifier_str_mv |
PICANÇO-DINIZ, D.L.W. et al. Does plasma ANP participate in natriuresis induced by a-MSH? Brazilian Journal of Medical and Biological Research, Ribeirão Preto, v. 30, n. 4, p. 459-463, abr. 1997. Disponível em: <http://www.scielo.br/pdf/bjmbr/v30n4/2786C.pdf>. Acesso em: 11 dez. 2012. <http://dx.doi.org/10.1590/S0100-879X1997000400005>. 1414-431X |
url |
http://repositorio.ufpa.br/jspui/handle/2011/3290 |
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eng |
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eng |
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info:eu-repo/semantics/openAccess |
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openAccess |
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