Kaposi’s sarcoma in persons living with HIV/AIDS: a case series in a tertiary referral hospital
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFPA |
Texto Completo: | http://repositorio.ufpa.br/jspui/handle/2011/10862 http://dx.doi.org/10.1590/abd1806-4841.20186978 |
Resumo: | Background: Kaposi’s sarcoma (KS) is a rare neoplasm with indolent progression. Since 1981, the Kaposi’s sarcoma epidemic has increased as co-infection with HIV. Objectives: The study aimed to identify the clinical and demographic characteristics and therapeutic approaches in HIV/AIDS patients in a regional referral hospital. Methods: We analyzed the medical records of 51 patients with histopathological diagnosis of Kaposi’s sarcoma hospitalized at Hospital Universitário João de Barros Barreto (HUJBB) from 2004 to 2015. Results: The study sample consisted of individuals 15 to 44 years of age (80.4%), male (80.4%), single (86.3%), and residing in Greater Metropolitan Belém, Pará State, Brazil. The primary skin lesions identified at diagnosis were violaceous macules (45%) and violaceous papules (25%). Visceral involvement was seen in 62.7%, mainly affecting the stomach (75%). The most frequent treatment regimen was 2 NRTI + NNRTI, and 60.8% were referred to chemotherapy. Study limitations: We assumed that more patients had been admitted to hospital without histopathological confirmation or with pathology reports from other services, so that the current study probably underestimated the number of KS cases. Conclusion: Although the cutaneous manifestations in most of these patients were non-exuberant skin lesions like macules and papules, many already showed visceral involvement. Meticulous screening of these patients is thus mandatory, even if the skin lesions are subtle and localized. |
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2019-04-03T17:42:22Z2019-04-03T17:42:22Z2018-08PIRES, Carla Andréa Avelar et al. Kaposi’s sarcoma in persons living with HIV/AIDS: a case series in a tertiary referral hospital. Anais Brasileiros de Dermatologia, Rio de Janeiro, v. 93, n. 4, p. 524-528, ago 2018. Disponível em: http://repositorio.ufpa.br/jspui/handle/2011/10862. Acesso em:.1806-4841http://repositorio.ufpa.br/jspui/handle/2011/10862http://dx.doi.org/10.1590/abd1806-4841.20186978Background: Kaposi’s sarcoma (KS) is a rare neoplasm with indolent progression. Since 1981, the Kaposi’s sarcoma epidemic has increased as co-infection with HIV. Objectives: The study aimed to identify the clinical and demographic characteristics and therapeutic approaches in HIV/AIDS patients in a regional referral hospital. Methods: We analyzed the medical records of 51 patients with histopathological diagnosis of Kaposi’s sarcoma hospitalized at Hospital Universitário João de Barros Barreto (HUJBB) from 2004 to 2015. Results: The study sample consisted of individuals 15 to 44 years of age (80.4%), male (80.4%), single (86.3%), and residing in Greater Metropolitan Belém, Pará State, Brazil. The primary skin lesions identified at diagnosis were violaceous macules (45%) and violaceous papules (25%). Visceral involvement was seen in 62.7%, mainly affecting the stomach (75%). The most frequent treatment regimen was 2 NRTI + NNRTI, and 60.8% were referred to chemotherapy. Study limitations: We assumed that more patients had been admitted to hospital without histopathological confirmation or with pathology reports from other services, so that the current study probably underestimated the number of KS cases. Conclusion: Although the cutaneous manifestations in most of these patients were non-exuberant skin lesions like macules and papules, many already showed visceral involvement. 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dc.title.pt_BR.fl_str_mv |
Kaposi’s sarcoma in persons living with HIV/AIDS: a case series in a tertiary referral hospital |
title |
Kaposi’s sarcoma in persons living with HIV/AIDS: a case series in a tertiary referral hospital |
spellingShingle |
Kaposi’s sarcoma in persons living with HIV/AIDS: a case series in a tertiary referral hospital PIRES, Carla Andréa Avelar Acquired immunodeficiency syndrome HIV Human herpesvirus 8 Kaposi’s sarcoma |
title_short |
Kaposi’s sarcoma in persons living with HIV/AIDS: a case series in a tertiary referral hospital |
title_full |
Kaposi’s sarcoma in persons living with HIV/AIDS: a case series in a tertiary referral hospital |
title_fullStr |
Kaposi’s sarcoma in persons living with HIV/AIDS: a case series in a tertiary referral hospital |
title_full_unstemmed |
Kaposi’s sarcoma in persons living with HIV/AIDS: a case series in a tertiary referral hospital |
title_sort |
Kaposi’s sarcoma in persons living with HIV/AIDS: a case series in a tertiary referral hospital |
author |
PIRES, Carla Andréa Avelar |
author_facet |
PIRES, Carla Andréa Avelar NORONHA, Marcos Antônio Neves MONTEIRO, Julius Caesar Mendes Soares COSTA, Albert Luiz Costa da ABREU JUNIOR, José Maria de Castro |
author_role |
author |
author2 |
NORONHA, Marcos Antônio Neves MONTEIRO, Julius Caesar Mendes Soares COSTA, Albert Luiz Costa da ABREU JUNIOR, José Maria de Castro |
author2_role |
author author author author |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/4043070406676676 http://lattes.cnpq.br/8100979196178150 http://lattes.cnpq.br/4692404138975316 http://lattes.cnpq.br/0910838783206481 http://lattes.cnpq.br/3888150171594943 |
dc.contributor.author.fl_str_mv |
PIRES, Carla Andréa Avelar NORONHA, Marcos Antônio Neves MONTEIRO, Julius Caesar Mendes Soares COSTA, Albert Luiz Costa da ABREU JUNIOR, José Maria de Castro |
dc.subject.por.fl_str_mv |
Acquired immunodeficiency syndrome HIV Human herpesvirus 8 Kaposi’s sarcoma |
topic |
Acquired immunodeficiency syndrome HIV Human herpesvirus 8 Kaposi’s sarcoma |
description |
Background: Kaposi’s sarcoma (KS) is a rare neoplasm with indolent progression. Since 1981, the Kaposi’s sarcoma epidemic has increased as co-infection with HIV. Objectives: The study aimed to identify the clinical and demographic characteristics and therapeutic approaches in HIV/AIDS patients in a regional referral hospital. Methods: We analyzed the medical records of 51 patients with histopathological diagnosis of Kaposi’s sarcoma hospitalized at Hospital Universitário João de Barros Barreto (HUJBB) from 2004 to 2015. Results: The study sample consisted of individuals 15 to 44 years of age (80.4%), male (80.4%), single (86.3%), and residing in Greater Metropolitan Belém, Pará State, Brazil. The primary skin lesions identified at diagnosis were violaceous macules (45%) and violaceous papules (25%). Visceral involvement was seen in 62.7%, mainly affecting the stomach (75%). The most frequent treatment regimen was 2 NRTI + NNRTI, and 60.8% were referred to chemotherapy. Study limitations: We assumed that more patients had been admitted to hospital without histopathological confirmation or with pathology reports from other services, so that the current study probably underestimated the number of KS cases. Conclusion: Although the cutaneous manifestations in most of these patients were non-exuberant skin lesions like macules and papules, many already showed visceral involvement. Meticulous screening of these patients is thus mandatory, even if the skin lesions are subtle and localized. |
publishDate |
2018 |
dc.date.issued.fl_str_mv |
2018-08 |
dc.date.accessioned.fl_str_mv |
2019-04-03T17:42:22Z |
dc.date.available.fl_str_mv |
2019-04-03T17:42:22Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
PIRES, Carla Andréa Avelar et al. Kaposi’s sarcoma in persons living with HIV/AIDS: a case series in a tertiary referral hospital. Anais Brasileiros de Dermatologia, Rio de Janeiro, v. 93, n. 4, p. 524-528, ago 2018. Disponível em: http://repositorio.ufpa.br/jspui/handle/2011/10862. Acesso em:. |
dc.identifier.uri.fl_str_mv |
http://repositorio.ufpa.br/jspui/handle/2011/10862 |
dc.identifier.issn.pt_BR.fl_str_mv |
1806-4841 |
dc.identifier.doi.pt_BR.fl_str_mv |
http://dx.doi.org/10.1590/abd1806-4841.20186978 |
identifier_str_mv |
PIRES, Carla Andréa Avelar et al. Kaposi’s sarcoma in persons living with HIV/AIDS: a case series in a tertiary referral hospital. Anais Brasileiros de Dermatologia, Rio de Janeiro, v. 93, n. 4, p. 524-528, ago 2018. Disponível em: http://repositorio.ufpa.br/jspui/handle/2011/10862. Acesso em:. 1806-4841 |
url |
http://repositorio.ufpa.br/jspui/handle/2011/10862 http://dx.doi.org/10.1590/abd1806-4841.20186978 |
dc.language.iso.fl_str_mv |
eng |
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eng |
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Anais Brasileiros de Dermatologia |
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openAccess |
dc.publisher.none.fl_str_mv |
Universidade Federal do Pará |
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UFPA |
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Brasil |
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Universidade Federal do Pará |
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