Qualidade de vida de adolescentes e adultos jovens vivendo com HIV/aids e sua associação com aspectos clínicos e adesão ao tratamento

Detalhes bibliográficos
Autor(a) principal: Carneiro, Rebeca Rocha
Data de Publicação: 2019
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Biblioteca Digital de Teses e Dissertações da UFPB
Texto Completo: https://repositorio.ufpb.br/jspui/handle/123456789/19677
Resumo: With the advent of high-potency antiretroviral therapy (ART), unequivocal benefits for reducing AIDS related morbidity and mortality, the increased survival of people living with HIV/AIDS has become a reality and these infected people have become concerned about their quality of life. Knowing and understanding the physical, psychological and social conditions that involve the patient, represents an important and indispensable tool for approaching people who live with this condition. In this context, adolescents and young adults who experience HIV and AIDS and its treatment so early stand out. Objective: to assess the health-related quality of life of adolescents and young adults living with HIV/AIDS and its association with clinical aspects, affective-sexual life and adherence to treatment. Method: Analytical and descriptive study, cross-sectional and quantitative in nature; held at a referral hospital for infectious diseases in the state of Paraíba, located in the city of João Pessoa – PB. Data were collected from February to May 2019. The population consisted of adolescents and young adults living with HIV/AIDS who were being followed up on an outpatient basis in this hospital and the sample involved 76 users. For data collection, a structured questionnaire was used containing sociodemographic, affective-sexual and clinical information, and specific instruments for assessing quality of life, the World Health Organization Quality of Life, shortened version (WHOQOL-HIV-Bref) and Scale Adherence to Treatment (CEAT-HIV). The data were analyzed using descriptive statistics, a Binary Logistic Regression model and a weight-based model of evidence, the Weight of Evidence (WoE). Results: Among the participants, there was an average age of 19 years, with a greater number of cases in the age group between 22 and 24 years; the majority are men (84.21%), single (73.69%), do not profess any kind of faith (50%) and the majority have completed high school (28.95%). With regard to affective-sexual life, the results demonstrate some types of vulnerability to which adolescents and young adults living with HIV/AIDS are exposed, where the majority are self-declared homosexual and the main form of exposure to HIV/AIDS was sexual , a representative portion reports not having a steady partner, remains in short-term relationships, sexual partners are unaware of their HIV-positive status, maintain relationships with HIV-negative individuals and use condoms discontinuously. In a WHOQOL-HIV-Bref analysis, the total quality of life score had a median equal to 66.38. Among the domains of the instrument, the most affected were the environment and psychological domains and the one that represents the best score was the physical domain. From the logistic regression model, it was possible to identify the variables that have a negative impact on quality of life, identifying as factors that decrease the chance for good quality of life: not having religion and being hospitalized. On the other hand, the model pointed out that having adherence to ART, being male, relating to a serodiscordant partner and having some type of religion are factors that increase the quality of life. There is a correlation between all domains of quality of life and adherence to ART. The generated WoE model contributes to strengthening the evidence pointed out by the logistic regression models for each domain, reinforcing in almost all domains the association between adherence to antiretroviral therapy and quality of life. Conclusion: The development of this investigation is opportune so that information about the epidemiology and the factors that interfere in the quality of life of this population are available to support decision-making by health professionals and related in order to prevent and control the factors that may affect the quality of life and adherence to the treatment of these people, fundamental characteristics for better living conditions after infection by the HIV virus.
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spelling Qualidade de vida de adolescentes e adultos jovens vivendo com HIV/aids e sua associação com aspectos clínicos e adesão ao tratamentoQualidade de vidaHIVAidsAdolescenteAdulto jovemQuality of lifeAdolescentYoung AdultCNPQ::CIENCIAS DA SAUDE::SAUDE COLETIVAWith the advent of high-potency antiretroviral therapy (ART), unequivocal benefits for reducing AIDS related morbidity and mortality, the increased survival of people living with HIV/AIDS has become a reality and these infected people have become concerned about their quality of life. Knowing and understanding the physical, psychological and social conditions that involve the patient, represents an important and indispensable tool for approaching people who live with this condition. In this context, adolescents and young adults who experience HIV and AIDS and its treatment so early stand out. Objective: to assess the health-related quality of life of adolescents and young adults living with HIV/AIDS and its association with clinical aspects, affective-sexual life and adherence to treatment. Method: Analytical and descriptive study, cross-sectional and quantitative in nature; held at a referral hospital for infectious diseases in the state of Paraíba, located in the city of João Pessoa – PB. Data were collected from February to May 2019. The population consisted of adolescents and young adults living with HIV/AIDS who were being followed up on an outpatient basis in this hospital and the sample involved 76 users. For data collection, a structured questionnaire was used containing sociodemographic, affective-sexual and clinical information, and specific instruments for assessing quality of life, the World Health Organization Quality of Life, shortened version (WHOQOL-HIV-Bref) and Scale Adherence to Treatment (CEAT-HIV). The data were analyzed using descriptive statistics, a Binary Logistic Regression model and a weight-based model of evidence, the Weight of Evidence (WoE). Results: Among the participants, there was an average age of 19 years, with a greater number of cases in the age group between 22 and 24 years; the majority are men (84.21%), single (73.69%), do not profess any kind of faith (50%) and the majority have completed high school (28.95%). With regard to affective-sexual life, the results demonstrate some types of vulnerability to which adolescents and young adults living with HIV/AIDS are exposed, where the majority are self-declared homosexual and the main form of exposure to HIV/AIDS was sexual , a representative portion reports not having a steady partner, remains in short-term relationships, sexual partners are unaware of their HIV-positive status, maintain relationships with HIV-negative individuals and use condoms discontinuously. In a WHOQOL-HIV-Bref analysis, the total quality of life score had a median equal to 66.38. Among the domains of the instrument, the most affected were the environment and psychological domains and the one that represents the best score was the physical domain. From the logistic regression model, it was possible to identify the variables that have a negative impact on quality of life, identifying as factors that decrease the chance for good quality of life: not having religion and being hospitalized. On the other hand, the model pointed out that having adherence to ART, being male, relating to a serodiscordant partner and having some type of religion are factors that increase the quality of life. There is a correlation between all domains of quality of life and adherence to ART. The generated WoE model contributes to strengthening the evidence pointed out by the logistic regression models for each domain, reinforcing in almost all domains the association between adherence to antiretroviral therapy and quality of life. Conclusion: The development of this investigation is opportune so that information about the epidemiology and the factors that interfere in the quality of life of this population are available to support decision-making by health professionals and related in order to prevent and control the factors that may affect the quality of life and adherence to the treatment of these people, fundamental characteristics for better living conditions after infection by the HIV virus.NenhumaCom o advento da terapia antirretroviral (TARV) de alta potência, benefícios inequívocos para redução da morbimortalidade associada à aids, o aumento da sobrevida das pessoas vivendo com HIV/aids tornou-se uma realidade e estas pessoas infectadas passaram a ter preocupações com a sua qualidade de vida. Conhecer e compreender as condições físicas, psicológicas e sociais, que envolvem o paciente, representa uma ferramenta importante e indispensável para abordagem das pessoas que vivem com esse agravo. Neste contexto, destacam-se os adolescentes e adultos jovens que experimentam tão cedo a vivência com o HIV/aids e com o seu tratamento. Objetivo: avaliar a qualidade de vida relacionada à saúde de adolescentes e adultos jovens vivendo com HIV/aids e sua associação com aspectos clínicos, vida afetivosexual e adesão ao tratamento. Método: Estudo analítico e descritivo, de corte transversal e natureza quantitativa; realizado em um hospital de referência em doenças infecciosas do Estado da Paraíba, localizado no município de João Pessoa–PB. Os dados foram coletados no período de fevereiro a maio de 2019. A população foi constituída por adolescente e adultos jovens vivendo com HIV/aids que estavam sendo acompanhados ambulatoriamente neste hospital e a amostra envolveu 76 usuários. Para coleta de dados, utilizou-se um questionário estruturado contendo informações sociodemográficas, afetivo-sexual e clínicas, e instrumentos específicos para avaliação da qualidade de vida, o World Health Organization Quality of Life, versão abreviada (WHOQOL-HIV-Bref) e Escala de Adesão ao Tratamento (CEAT-HIV). Os dados foram analisados por meio da estatística descritiva, por um modelo de Regressão Logística Binária e um modelo baseado no peso da evidência, o Weight of Evidence (WoE). Resultados: Dentre os participantes, houve idade média de 19 anos, com maior número de casos na faixa etária entre 22 e 24 anos; a maioria é homem (84,21%), solteiros (73,69%), não professa nenhum tipo de fé (50%) e a maioria com ensino médio completo (28,95%). No que diz respeito a vida afetivo-sexual, os resultados demonstram alguns tipos de vulnerabilidade com que adolescentes e adultos jovens vivendo com HIV/aids estão expostos, onde a maioria é autodeclarado homossexual e a principal forma de exposição para HIV/aids foi a sexual, uma parcela representativa relata não ter parceiro fixo, permanece em relacionamentos em curto período, os parceiros sexuais desconhecem sua soropositividade, mantem relacionamentos com indivíduos soronegativo e usam preservativos de maneira descontinuada. Em análise do WHOQOL-HIV-Bref, o escore total da qualidade de vida obteve mediana igual a 66,38. Dentre os domínios do instrumento, os mais afetados foram os domínios meio ambiente e psicológico e o que representa melhor escore foi o domínio físico. A partir do modelo de regressão logística foi possível identificar as variáveis que possuem impacto negativo na qualidade de vida, identificando como fatores que diminuem a chance para boa qualidade de vida: não ter religião e estar internado. Em contrapartida o modelo apontou que ter adesão à TARV, ser do sexo masculino, relacionar-se com parceiro sorodiscordante e ter algum tipo de religião são fatores que aumentam a qualidade de vida. Existe correlação entre todos os domínios de qualidade de vida e adesão a TARV. O modelo WoE gerado, contribui para fortalecer as evidências apontadas pelos modelos de regressão logística para cada domínio, reforçando em quase todos os domínios a associação entre a adesão a terapia antirretroviral e a qualidade de vida. Conclusão: O desenvolvimento dessa investigação é oportuno para que informações acerca da epidemiologia e dos fatores que interferem na qualidade de vida desta população sejam disponibilizadas para subsidiar tomada de decisões de profissionais da área da saúde e correlatas no sentido de prevenir e controlar os fatores que podem afetar a qualidade de vida e a adesão ao tratamento destas pessoas, características fundamentais para melhores condições de vida após a infecção pelo vírus HIV.Universidade Federal da ParaíbaBrasilCiências Exatas e da SaúdePrograma de Pós-Graduação em Modelos de Decisão e SaúdeUFPBLima, Caliandra Maria Bezerra Lunahttp://lattes.cnpq.br/6515725808648467Coêlho, Hemílio Fernandes Camposhttp://lattes.cnpq.br/2328238717105962Carneiro, Rebeca Rocha2021-03-05T17:24:32Z2020-02-172021-03-05T17:24:32Z2019-12-16info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesishttps://repositorio.ufpb.br/jspui/handle/123456789/19677porhttp://creativecommons.org/licenses/by-nd/3.0/br/info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UFPBinstname:Universidade Federal da Paraíba (UFPB)instacron:UFPB2021-07-02T23:28:59Zoai:repositorio.ufpb.br:123456789/19677Biblioteca Digital de Teses e Dissertaçõeshttps://repositorio.ufpb.br/PUBhttp://tede.biblioteca.ufpb.br:8080/oai/requestdiretoria@ufpb.br|| diretoria@ufpb.bropendoar:2021-07-02T23:28:59Biblioteca Digital de Teses e Dissertações da UFPB - Universidade Federal da Paraíba (UFPB)false
dc.title.none.fl_str_mv Qualidade de vida de adolescentes e adultos jovens vivendo com HIV/aids e sua associação com aspectos clínicos e adesão ao tratamento
title Qualidade de vida de adolescentes e adultos jovens vivendo com HIV/aids e sua associação com aspectos clínicos e adesão ao tratamento
spellingShingle Qualidade de vida de adolescentes e adultos jovens vivendo com HIV/aids e sua associação com aspectos clínicos e adesão ao tratamento
Carneiro, Rebeca Rocha
Qualidade de vida
HIV
Aids
Adolescente
Adulto jovem
Quality of life
Adolescent
Young Adult
CNPQ::CIENCIAS DA SAUDE::SAUDE COLETIVA
title_short Qualidade de vida de adolescentes e adultos jovens vivendo com HIV/aids e sua associação com aspectos clínicos e adesão ao tratamento
title_full Qualidade de vida de adolescentes e adultos jovens vivendo com HIV/aids e sua associação com aspectos clínicos e adesão ao tratamento
title_fullStr Qualidade de vida de adolescentes e adultos jovens vivendo com HIV/aids e sua associação com aspectos clínicos e adesão ao tratamento
title_full_unstemmed Qualidade de vida de adolescentes e adultos jovens vivendo com HIV/aids e sua associação com aspectos clínicos e adesão ao tratamento
title_sort Qualidade de vida de adolescentes e adultos jovens vivendo com HIV/aids e sua associação com aspectos clínicos e adesão ao tratamento
author Carneiro, Rebeca Rocha
author_facet Carneiro, Rebeca Rocha
author_role author
dc.contributor.none.fl_str_mv Lima, Caliandra Maria Bezerra Luna
http://lattes.cnpq.br/6515725808648467
Coêlho, Hemílio Fernandes Campos
http://lattes.cnpq.br/2328238717105962
dc.contributor.author.fl_str_mv Carneiro, Rebeca Rocha
dc.subject.por.fl_str_mv Qualidade de vida
HIV
Aids
Adolescente
Adulto jovem
Quality of life
Adolescent
Young Adult
CNPQ::CIENCIAS DA SAUDE::SAUDE COLETIVA
topic Qualidade de vida
HIV
Aids
Adolescente
Adulto jovem
Quality of life
Adolescent
Young Adult
CNPQ::CIENCIAS DA SAUDE::SAUDE COLETIVA
description With the advent of high-potency antiretroviral therapy (ART), unequivocal benefits for reducing AIDS related morbidity and mortality, the increased survival of people living with HIV/AIDS has become a reality and these infected people have become concerned about their quality of life. Knowing and understanding the physical, psychological and social conditions that involve the patient, represents an important and indispensable tool for approaching people who live with this condition. In this context, adolescents and young adults who experience HIV and AIDS and its treatment so early stand out. Objective: to assess the health-related quality of life of adolescents and young adults living with HIV/AIDS and its association with clinical aspects, affective-sexual life and adherence to treatment. Method: Analytical and descriptive study, cross-sectional and quantitative in nature; held at a referral hospital for infectious diseases in the state of Paraíba, located in the city of João Pessoa – PB. Data were collected from February to May 2019. The population consisted of adolescents and young adults living with HIV/AIDS who were being followed up on an outpatient basis in this hospital and the sample involved 76 users. For data collection, a structured questionnaire was used containing sociodemographic, affective-sexual and clinical information, and specific instruments for assessing quality of life, the World Health Organization Quality of Life, shortened version (WHOQOL-HIV-Bref) and Scale Adherence to Treatment (CEAT-HIV). The data were analyzed using descriptive statistics, a Binary Logistic Regression model and a weight-based model of evidence, the Weight of Evidence (WoE). Results: Among the participants, there was an average age of 19 years, with a greater number of cases in the age group between 22 and 24 years; the majority are men (84.21%), single (73.69%), do not profess any kind of faith (50%) and the majority have completed high school (28.95%). With regard to affective-sexual life, the results demonstrate some types of vulnerability to which adolescents and young adults living with HIV/AIDS are exposed, where the majority are self-declared homosexual and the main form of exposure to HIV/AIDS was sexual , a representative portion reports not having a steady partner, remains in short-term relationships, sexual partners are unaware of their HIV-positive status, maintain relationships with HIV-negative individuals and use condoms discontinuously. In a WHOQOL-HIV-Bref analysis, the total quality of life score had a median equal to 66.38. Among the domains of the instrument, the most affected were the environment and psychological domains and the one that represents the best score was the physical domain. From the logistic regression model, it was possible to identify the variables that have a negative impact on quality of life, identifying as factors that decrease the chance for good quality of life: not having religion and being hospitalized. On the other hand, the model pointed out that having adherence to ART, being male, relating to a serodiscordant partner and having some type of religion are factors that increase the quality of life. There is a correlation between all domains of quality of life and adherence to ART. The generated WoE model contributes to strengthening the evidence pointed out by the logistic regression models for each domain, reinforcing in almost all domains the association between adherence to antiretroviral therapy and quality of life. Conclusion: The development of this investigation is opportune so that information about the epidemiology and the factors that interfere in the quality of life of this population are available to support decision-making by health professionals and related in order to prevent and control the factors that may affect the quality of life and adherence to the treatment of these people, fundamental characteristics for better living conditions after infection by the HIV virus.
publishDate 2019
dc.date.none.fl_str_mv 2019-12-16
2020-02-17
2021-03-05T17:24:32Z
2021-03-05T17:24:32Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
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language por
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dc.publisher.none.fl_str_mv Universidade Federal da Paraíba
Brasil
Ciências Exatas e da Saúde
Programa de Pós-Graduação em Modelos de Decisão e Saúde
UFPB
publisher.none.fl_str_mv Universidade Federal da Paraíba
Brasil
Ciências Exatas e da Saúde
Programa de Pós-Graduação em Modelos de Decisão e Saúde
UFPB
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