Efeitos da administração de Butafosfan e Cianocobalamina após o parto, sobre parâmetros metabólicos e produtivos de vacas leiteiras

Detalhes bibliográficos
Autor(a) principal: Pereira, Rubens Alves
Data de Publicação: 2010
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Repositório Institucional da UFPel - Guaiaca
Texto Completo: http://guaiaca.ufpel.edu.br/handle/123456789/1271
Resumo: The aim of this study was to determine the effects of intramuscular injection of Butaphosphan and Cyanocobalamin on the parameters of energy metabolism, protein, enzyme, mineral and livestock of dairy cows in the postpartum period. We used 52 animals of the Holstein breed. The experimental period ranged from birth to 150 days of lactation. These cows were divided into 3 groups: BC10 (n=18), who received 5 doses of 10mL of solution of Butaphosphan+Cyanocobalamin, BC20 (n=18), who received 5 doses of 20mL of Butaphosphan+Cyanocobalamin; and CG (n=16), used as a control group received 5 doses of 10mL of saline (NaCl 0.9%). Administrations were performed with an interval of 5 days, intramuscularly, and blood samples every 5 days. Evaluations were performed on body condition score (BCS) and productive performance during the postpartum period and measurements of metabolic parameters such as blood glucose, nonesterified fatty acid (NEFA), urea, calcium (Ca), phosphorus (P), magnesium (Mg), aspartate aminotransferase (AST), gamma-glutamyltransferase (GGT) and ketone (CC) in urine. The measurements of blood glucose were not changed during the study period. The blood levels of NEFA were higher (P<0.05) for the GC compared to BC10 and BC20, which also differed (P<0.05). Urea levels did not differ between groups (P>0.05). There were no differences (P>0.05) in the metabolites Ca, P, Ca: P, Mg and CC in the urine. The same finding was common to liver enzymes, AST and GGT. The animals in groups BC10 and BC20 had a milk production higher than the GC (P<0.05), but did not differ (P>0.05). The analysis of milk components were similar (P>0.05) between groups. These results demonstrated that the use of Butaphosphan and Cyanocobalamin in dairy cows during the postpartum period, is effective in alleviating the negative energy balance and improving the productive performance, without causing liver overload.
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spelling 2014-08-20T13:32:54Z2010-08-042014-08-20T13:32:54Z2010-02-26PEREIRA, Rubens Alves. Effects of administration of Butafosfan and Cyanocobalamin postpartum on metabolic parameters and production of dairy cows. 2010. 33 f. Dissertação (Mestrado em Biotecnologia) - Universidade Federal de Pelotas, Pelotas, 2010.http://guaiaca.ufpel.edu.br/handle/123456789/1271The aim of this study was to determine the effects of intramuscular injection of Butaphosphan and Cyanocobalamin on the parameters of energy metabolism, protein, enzyme, mineral and livestock of dairy cows in the postpartum period. We used 52 animals of the Holstein breed. The experimental period ranged from birth to 150 days of lactation. These cows were divided into 3 groups: BC10 (n=18), who received 5 doses of 10mL of solution of Butaphosphan+Cyanocobalamin, BC20 (n=18), who received 5 doses of 20mL of Butaphosphan+Cyanocobalamin; and CG (n=16), used as a control group received 5 doses of 10mL of saline (NaCl 0.9%). Administrations were performed with an interval of 5 days, intramuscularly, and blood samples every 5 days. Evaluations were performed on body condition score (BCS) and productive performance during the postpartum period and measurements of metabolic parameters such as blood glucose, nonesterified fatty acid (NEFA), urea, calcium (Ca), phosphorus (P), magnesium (Mg), aspartate aminotransferase (AST), gamma-glutamyltransferase (GGT) and ketone (CC) in urine. The measurements of blood glucose were not changed during the study period. The blood levels of NEFA were higher (P<0.05) for the GC compared to BC10 and BC20, which also differed (P<0.05). Urea levels did not differ between groups (P>0.05). There were no differences (P>0.05) in the metabolites Ca, P, Ca: P, Mg and CC in the urine. The same finding was common to liver enzymes, AST and GGT. The animals in groups BC10 and BC20 had a milk production higher than the GC (P<0.05), but did not differ (P>0.05). The analysis of milk components were similar (P>0.05) between groups. These results demonstrated that the use of Butaphosphan and Cyanocobalamin in dairy cows during the postpartum period, is effective in alleviating the negative energy balance and improving the productive performance, without causing liver overload.O objetivo deste estudo foi determinar os efeitos da administração de Butafosfan e Cianocobalamina sobre os parâmetros do metabolismo energético, protéico, enzimático, mineral, produção e composição do leite de vacas leiteiras durante o período pós-parto. Foram utilizados no experimento 52 vacas da raça Holandês, avaliadas do parto até 150 dias de lactação. Estas vacas foram divididas em 3 grupos experimentais: o BC10 (n=18), que recebeu 5 doses de 10mL de solução aquosa de Butafosfan+Cianocobalamina; o BC20 (n=18), que recebeu 5 doses de 20mL de solução aquosa de Butafosfan+Cianocobalamina; e o grupo controle (GC n=16), que recebeu 5 doses de 10mL de solução fisiológica (NaCl 0,9%). Foram realizadas administrações logo após o parto, com intervalo de 5 dias, por via intramuscular. Foi coletado sangue a cada 15 dias a partir do terceiro dia pós-parto para a determinação dos níveis de glicose, ácidos graxos não esterificados (NEFA), β-hidroxibutirato (BHBA), uréia, cálcio (Ca), fósforo (P), magnésio (Mg), aspartato aminotransferase (AST) e gama-glutamiltransferase (GGT). Foi coletada urina a cada 15 dias a partir do terceiro dia pós-parto para a determinação de corpos cetônicos (CC). Avaliou-se o escore de condição corporal (ECC) e produção leiteira. Todos os grupos diferiram entre si quanto aos níveis de NEFA, sendo maiores no GC. Os grupos BC10 e BC20 diferiram entre si, sendo superiores no BC10. Os níveis de BHBA foram maiores no GC em relação ao BC10 e BC20, os quais não diferiram entre si. Quanto às avaliações zootécnicas, os grupos BC10 e BC20 apresentaram uma produção leiteira maior que o GC, porém não diferiram entre si. As concentrações dos componentes do leite não foram alteradas até 150 dias da lactação. Estes resultados demonstraram que a solução de Butafosfan e Cianocobalamina, administradas em vacas leiteiras após o parto, reduz o balanço energético negativo e aumenta a produção de leite, sem sobrecarregas o fígado.application/pdfporUniversidade Federal de PelotasPrograma de Pós-Graduação em BiotecnologiaUFPelBRBiotecnologiaButaphosphanCyanocobalaminDairy cowsMetabolic profileButafosfanCianocobalaminaVacas leiteirasPerfil metabólicoCNPQ::CIENCIAS BIOLOGICAS::BIOQUIMICAEfeitos da administração de Butafosfan e Cianocobalamina após o parto, sobre parâmetros metabólicos e produtivos de vacas leiteirasEffects of administration of Butafosfan and Cyanocobalamin postpartum on metabolic parameters and production of dairy cowsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesishttp://lattes.cnpq.br/9102148663168870http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4796653E9Corrêa, Márcio NunesPereira, Rubens Alvesinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFPel - Guaiacainstname:Universidade Federal de Pelotas (UFPEL)instacron:UFPELORIGINALdissertacao_rubens_alves_pereira.pdfapplication/pdf581091http://guaiaca.ufpel.edu.br/xmlui/bitstream/123456789/1271/1/dissertacao_rubens_alves_pereira.pdf129866c31d5af8b07ef3e33c3e342067MD51open accessTEXTdissertacao_rubens_alves_pereira.pdf.txtdissertacao_rubens_alves_pereira.pdf.txtExtracted Texttext/plain65112http://guaiaca.ufpel.edu.br/xmlui/bitstream/123456789/1271/2/dissertacao_rubens_alves_pereira.pdf.txt091d0e67895deb3c4ded7a56023dc297MD52open accessTHUMBNAILdissertacao_rubens_alves_pereira.pdf.jpgdissertacao_rubens_alves_pereira.pdf.jpgGenerated Thumbnailimage/jpeg1738http://guaiaca.ufpel.edu.br/xmlui/bitstream/123456789/1271/3/dissertacao_rubens_alves_pereira.pdf.jpg3e1583c772dc9f67bb86670b42120127MD53open access123456789/12712019-08-23 10:19:14.079open accessoai:guaiaca.ufpel.edu.br:123456789/1271Repositório InstitucionalPUBhttp://repositorio.ufpel.edu.br/oai/requestrippel@ufpel.edu.br || repositorio@ufpel.edu.br || aline.batista@ufpel.edu.bropendoar:2019-08-23T13:19:14Repositório Institucional da UFPel - Guaiaca - Universidade Federal de Pelotas (UFPEL)false
dc.title.por.fl_str_mv Efeitos da administração de Butafosfan e Cianocobalamina após o parto, sobre parâmetros metabólicos e produtivos de vacas leiteiras
dc.title.alternative.eng.fl_str_mv Effects of administration of Butafosfan and Cyanocobalamin postpartum on metabolic parameters and production of dairy cows
title Efeitos da administração de Butafosfan e Cianocobalamina após o parto, sobre parâmetros metabólicos e produtivos de vacas leiteiras
spellingShingle Efeitos da administração de Butafosfan e Cianocobalamina após o parto, sobre parâmetros metabólicos e produtivos de vacas leiteiras
Pereira, Rubens Alves
Butaphosphan
Cyanocobalamin
Dairy cows
Metabolic profile
Butafosfan
Cianocobalamina
Vacas leiteiras
Perfil metabólico
CNPQ::CIENCIAS BIOLOGICAS::BIOQUIMICA
title_short Efeitos da administração de Butafosfan e Cianocobalamina após o parto, sobre parâmetros metabólicos e produtivos de vacas leiteiras
title_full Efeitos da administração de Butafosfan e Cianocobalamina após o parto, sobre parâmetros metabólicos e produtivos de vacas leiteiras
title_fullStr Efeitos da administração de Butafosfan e Cianocobalamina após o parto, sobre parâmetros metabólicos e produtivos de vacas leiteiras
title_full_unstemmed Efeitos da administração de Butafosfan e Cianocobalamina após o parto, sobre parâmetros metabólicos e produtivos de vacas leiteiras
title_sort Efeitos da administração de Butafosfan e Cianocobalamina após o parto, sobre parâmetros metabólicos e produtivos de vacas leiteiras
author Pereira, Rubens Alves
author_facet Pereira, Rubens Alves
author_role author
dc.contributor.authorLattes.por.fl_str_mv http://lattes.cnpq.br/9102148663168870
dc.contributor.advisorLattes.por.fl_str_mv http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4796653E9
dc.contributor.advisor1.fl_str_mv Corrêa, Márcio Nunes
dc.contributor.author.fl_str_mv Pereira, Rubens Alves
contributor_str_mv Corrêa, Márcio Nunes
dc.subject.eng.fl_str_mv Butaphosphan
Cyanocobalamin
Dairy cows
Metabolic profile
topic Butaphosphan
Cyanocobalamin
Dairy cows
Metabolic profile
Butafosfan
Cianocobalamina
Vacas leiteiras
Perfil metabólico
CNPQ::CIENCIAS BIOLOGICAS::BIOQUIMICA
dc.subject.por.fl_str_mv Butafosfan
Cianocobalamina
Vacas leiteiras
Perfil metabólico
dc.subject.cnpq.fl_str_mv CNPQ::CIENCIAS BIOLOGICAS::BIOQUIMICA
description The aim of this study was to determine the effects of intramuscular injection of Butaphosphan and Cyanocobalamin on the parameters of energy metabolism, protein, enzyme, mineral and livestock of dairy cows in the postpartum period. We used 52 animals of the Holstein breed. The experimental period ranged from birth to 150 days of lactation. These cows were divided into 3 groups: BC10 (n=18), who received 5 doses of 10mL of solution of Butaphosphan+Cyanocobalamin, BC20 (n=18), who received 5 doses of 20mL of Butaphosphan+Cyanocobalamin; and CG (n=16), used as a control group received 5 doses of 10mL of saline (NaCl 0.9%). Administrations were performed with an interval of 5 days, intramuscularly, and blood samples every 5 days. Evaluations were performed on body condition score (BCS) and productive performance during the postpartum period and measurements of metabolic parameters such as blood glucose, nonesterified fatty acid (NEFA), urea, calcium (Ca), phosphorus (P), magnesium (Mg), aspartate aminotransferase (AST), gamma-glutamyltransferase (GGT) and ketone (CC) in urine. The measurements of blood glucose were not changed during the study period. The blood levels of NEFA were higher (P<0.05) for the GC compared to BC10 and BC20, which also differed (P<0.05). Urea levels did not differ between groups (P>0.05). There were no differences (P>0.05) in the metabolites Ca, P, Ca: P, Mg and CC in the urine. The same finding was common to liver enzymes, AST and GGT. The animals in groups BC10 and BC20 had a milk production higher than the GC (P<0.05), but did not differ (P>0.05). The analysis of milk components were similar (P>0.05) between groups. These results demonstrated that the use of Butaphosphan and Cyanocobalamin in dairy cows during the postpartum period, is effective in alleviating the negative energy balance and improving the productive performance, without causing liver overload.
publishDate 2010
dc.date.available.fl_str_mv 2010-08-04
2014-08-20T13:32:54Z
dc.date.issued.fl_str_mv 2010-02-26
dc.date.accessioned.fl_str_mv 2014-08-20T13:32:54Z
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dc.identifier.citation.fl_str_mv PEREIRA, Rubens Alves. Effects of administration of Butafosfan and Cyanocobalamin postpartum on metabolic parameters and production of dairy cows. 2010. 33 f. Dissertação (Mestrado em Biotecnologia) - Universidade Federal de Pelotas, Pelotas, 2010.
dc.identifier.uri.fl_str_mv http://guaiaca.ufpel.edu.br/handle/123456789/1271
identifier_str_mv PEREIRA, Rubens Alves. Effects of administration of Butafosfan and Cyanocobalamin postpartum on metabolic parameters and production of dairy cows. 2010. 33 f. Dissertação (Mestrado em Biotecnologia) - Universidade Federal de Pelotas, Pelotas, 2010.
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