Influência da somatotropina recombinante bovina (rBST) sobre parâmetros metabólicos, hormonais e de qualidade de sêmen em touros
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFPel - Guaiaca |
Texto Completo: | http://repositorio.ufpel.edu.br/handle/ri/2541 |
Resumo: | The growth hormone (GH) have as main function improve proliferation and cellular development, but also participates of processes related to the immune system and reproductive function. The effect of GH is exerted by the IGF-I (insulin-like growth factor I), that is a hormone polypeptidic mitotic secreted by all cells that carry through mitosis. Since the development of the recombinant form of the bovine recombinant somatotropin (rBST) various studies have been developed on milk and meat production in farm animals. The objective of this study was to evaluate the effect of rBST on metabolic markers of energetic, protein, mineral and hepatic metabolism, as well as, to evaluate its effect on concentrations of IGF-I, insulin and quality parameters semen in bulls. This study was carried in central of artificial insemination ABS/PECPLAN using 20 bulls of european breeds. These animals were divided in two groups, a group that received a placebo application (NaCl, 0.9%) and another that received rBST (Lactotropin®/Elanco Animal Health). Five blood collections for evaluation of metabolic and hormonal markers and 6 semen collections with posterior freezing for the accomplishment of the corresponding semen evaluations. There was no effect of rBST (P > 0,05) in metabolic markers, except in the concentration of gamma- glutamyltransferase (GGT), that increased in the group that received rBST (P < 0,05), but inside the physiological range, in the hormones evaluations, IGF-I increased in the group treated with rBST (P < 0,05), but there wasn t difference in the insulin concentrations (P > 0,05). In relation to the semen evaluations, there were no differences observed (P > 0,05) in motility and morphology evaluated in the period before freezing. In after freezing evaluations, being that motility, morphology, integrity of plasmatic membrane by fluorescent sounding leads and the hiposmotic test, differences have been observed (P < 0,05) between groups, showing beneficial effect of rBST in these characteristics. In this way can be observed that rBST, beyond raising the IGF-I levels positively influenced the seminal after freezing characteristics evaluated without causing disequilibrium in the metabolism of treated animals since the concentrations of the evaluated metabolic markers were in accordance with the physiological standards for the bovine species. |
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2014-08-20T14:37:58Z2009-12-102014-08-20T14:37:58Z2007-05-07VIEIRA, Marcelo Brandi. Influence of bovine recombinant somatotropin (rBST) on metabolic parameters, hormones and semen quality of bulls. 2007. 71 f. Dissertação (Mestrado em Veterinária) - Universidade Federal de Pelotas, Pelotas, 2007.http://repositorio.ufpel.edu.br/handle/ri/2541The growth hormone (GH) have as main function improve proliferation and cellular development, but also participates of processes related to the immune system and reproductive function. The effect of GH is exerted by the IGF-I (insulin-like growth factor I), that is a hormone polypeptidic mitotic secreted by all cells that carry through mitosis. Since the development of the recombinant form of the bovine recombinant somatotropin (rBST) various studies have been developed on milk and meat production in farm animals. The objective of this study was to evaluate the effect of rBST on metabolic markers of energetic, protein, mineral and hepatic metabolism, as well as, to evaluate its effect on concentrations of IGF-I, insulin and quality parameters semen in bulls. This study was carried in central of artificial insemination ABS/PECPLAN using 20 bulls of european breeds. These animals were divided in two groups, a group that received a placebo application (NaCl, 0.9%) and another that received rBST (Lactotropin®/Elanco Animal Health). Five blood collections for evaluation of metabolic and hormonal markers and 6 semen collections with posterior freezing for the accomplishment of the corresponding semen evaluations. There was no effect of rBST (P > 0,05) in metabolic markers, except in the concentration of gamma- glutamyltransferase (GGT), that increased in the group that received rBST (P < 0,05), but inside the physiological range, in the hormones evaluations, IGF-I increased in the group treated with rBST (P < 0,05), but there wasn t difference in the insulin concentrations (P > 0,05). In relation to the semen evaluations, there were no differences observed (P > 0,05) in motility and morphology evaluated in the period before freezing. In after freezing evaluations, being that motility, morphology, integrity of plasmatic membrane by fluorescent sounding leads and the hiposmotic test, differences have been observed (P < 0,05) between groups, showing beneficial effect of rBST in these characteristics. In this way can be observed that rBST, beyond raising the IGF-I levels positively influenced the seminal after freezing characteristics evaluated without causing disequilibrium in the metabolism of treated animals since the concentrations of the evaluated metabolic markers were in accordance with the physiological standards for the bovine species.O hormônio do crescimento (GH) possui como principal função realizar a proliferação e desenvolvimento celular, participando também de processos relacionados ao sistema imune e a reprodução. O efeito do GH é exercido pelo IGF-I (fator de crescimento semelhante à insulina I), que é um hormônio polipeptídico mitótico secretado por todas as células que realizam mitose. A partir do desenvolvimento da forma recombinante da somatotropina recombinante bovina (rBST) foram desenvolvidos inúmeros estudos relacionados a produção de leite e carne em animais de produção. O objetivo deste estudo foi avaliar o efeito do rBST sobre marcadores metabólicos relacionados ao metabolismo energético, protéico, mineral e hepático, bem como avaliar o seu efeito nas concentrações de IGF-I, insulina e nos parâmetros de qualidade de sêmen em touros. Este estudo foi realizado na central de inseminação artificial ABS/PECPLAN, com 20 touros de raças predominantemente européias. Estes animais foram divididos em dois grupos, sendo que um grupo recebeu a aplicação do placebo (solução fisiológica, NaCl 0,9%) e outro rBST (Lactotropin®/Elanco Saúde Animal). Foram realizados 5 coletas de sangue para avaliação dos marcadores metabólicos e hormonais e 6 coletas de sêmen com posterior congelamento para a realização das correspondentes avaliações de sêmen. De acordo com os resultados não foi observado (P > 0,05) efeito do rBST nas avaliações dos marcadores metabólicos, exceto nas concentrações da enzima hepática gama - glutamiltransferase (GGT), que foi mais elevada no grupo que recebeu o rBST (P < 0,05), mas de acordo com os padrões fisiológicos. Nas avaliações hormonais os níveis de IGF-I foram mais elevados no grupo tratado com rBST (P < 0,05), não sendo, porém, observadas diferenças para os níveis de insulina (P > 0,05). Em relação às avaliações de sêmen, não foram observadas diferenças entre os dois grupos (P > 0,05) na motilidade e morfologia espermática avaliadas no período pré-congelamento. Nas avaliações pós-congelamento que incluíam a motilidade, morfologia, integridade de membrana plasmática por sondas fluorescentes e pelo teste hiposmótico foram observadas diferenças (P < 0,05) entre os grupos, sendo demonstrado melhores índices no grupo que recebeu o tratamento com rBST. Desta forma pode-se observar que o rBST, além de elevar o níveis de IGF-I, influenciou positivamente as características seminais avaliadas no pós-congelamento sem que tivesse ocasionado desequilíbrio no metabolismo dos animais tratados, já que as concentrações dos marcadores metabólicos avaliados estavam de acordo com os padrões fisiológicos para a espécie bovina.application/pdfporUniversidade Federal de PelotasPrograma de Pós-Graduação em VeterináriaUFPelBRVeterináriaVeterináriaMetabolismoTourosrBSTReproduçãoBullsMetabolismrBSTReproductionCNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIAInfluência da somatotropina recombinante bovina (rBST) sobre parâmetros metabólicos, hormonais e de qualidade de sêmen em tourosInfluence of bovine recombinant somatotropin (rBST) on metabolic parameters, hormones and semen quality of bullsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesishttp://lattes.cnpq.br/3324076914071687http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4796653E9Corrêa, Márcio NunesVieira, Marcelo Brandiinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFPel - Guaiacainstname:Universidade Federal de Pelotas (UFPEL)instacron:UFPELORIGINALdissertacao_marcelo_vieira.pdfapplication/pdf644753http://guaiaca.ufpel.edu.br/xmlui/bitstream/123456789/2541/1/dissertacao_marcelo_vieira.pdfe45dacce2e978ab7c293923a447f7290MD51open accessTEXTdissertacao_marcelo_vieira.pdf.txtdissertacao_marcelo_vieira.pdf.txtExtracted Texttext/plain114618http://guaiaca.ufpel.edu.br/xmlui/bitstream/123456789/2541/2/dissertacao_marcelo_vieira.pdf.txt5675d6da64d23528e21e71df32976d45MD52open accessTHUMBNAILdissertacao_marcelo_vieira.pdf.jpgdissertacao_marcelo_vieira.pdf.jpgGenerated Thumbnailimage/jpeg1696http://guaiaca.ufpel.edu.br/xmlui/bitstream/123456789/2541/3/dissertacao_marcelo_vieira.pdf.jpgd6fa745f0fea82a2fa4fd9b1c9b31a14MD53open access123456789/25412019-09-13 09:57:08.986open accessoai:guaiaca.ufpel.edu.br:123456789/2541Repositório InstitucionalPUBhttp://repositorio.ufpel.edu.br/oai/requestrippel@ufpel.edu.br || repositorio@ufpel.edu.br || aline.batista@ufpel.edu.bropendoar:2019-09-13T12:57:08Repositório Institucional da UFPel - Guaiaca - Universidade Federal de Pelotas (UFPEL)false |
dc.title.por.fl_str_mv |
Influência da somatotropina recombinante bovina (rBST) sobre parâmetros metabólicos, hormonais e de qualidade de sêmen em touros |
dc.title.alternative.eng.fl_str_mv |
Influence of bovine recombinant somatotropin (rBST) on metabolic parameters, hormones and semen quality of bulls |
title |
Influência da somatotropina recombinante bovina (rBST) sobre parâmetros metabólicos, hormonais e de qualidade de sêmen em touros |
spellingShingle |
Influência da somatotropina recombinante bovina (rBST) sobre parâmetros metabólicos, hormonais e de qualidade de sêmen em touros Vieira, Marcelo Brandi Veterinária Metabolismo Touros rBST Reprodução Bulls Metabolism rBST Reproduction CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA |
title_short |
Influência da somatotropina recombinante bovina (rBST) sobre parâmetros metabólicos, hormonais e de qualidade de sêmen em touros |
title_full |
Influência da somatotropina recombinante bovina (rBST) sobre parâmetros metabólicos, hormonais e de qualidade de sêmen em touros |
title_fullStr |
Influência da somatotropina recombinante bovina (rBST) sobre parâmetros metabólicos, hormonais e de qualidade de sêmen em touros |
title_full_unstemmed |
Influência da somatotropina recombinante bovina (rBST) sobre parâmetros metabólicos, hormonais e de qualidade de sêmen em touros |
title_sort |
Influência da somatotropina recombinante bovina (rBST) sobre parâmetros metabólicos, hormonais e de qualidade de sêmen em touros |
author |
Vieira, Marcelo Brandi |
author_facet |
Vieira, Marcelo Brandi |
author_role |
author |
dc.contributor.authorLattes.por.fl_str_mv |
http://lattes.cnpq.br/3324076914071687 |
dc.contributor.advisorLattes.por.fl_str_mv |
http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4796653E9 |
dc.contributor.advisor1.fl_str_mv |
Corrêa, Márcio Nunes |
dc.contributor.author.fl_str_mv |
Vieira, Marcelo Brandi |
contributor_str_mv |
Corrêa, Márcio Nunes |
dc.subject.por.fl_str_mv |
Veterinária Metabolismo Touros rBST Reprodução |
topic |
Veterinária Metabolismo Touros rBST Reprodução Bulls Metabolism rBST Reproduction CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA |
dc.subject.eng.fl_str_mv |
Bulls Metabolism rBST Reproduction |
dc.subject.cnpq.fl_str_mv |
CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA |
description |
The growth hormone (GH) have as main function improve proliferation and cellular development, but also participates of processes related to the immune system and reproductive function. The effect of GH is exerted by the IGF-I (insulin-like growth factor I), that is a hormone polypeptidic mitotic secreted by all cells that carry through mitosis. Since the development of the recombinant form of the bovine recombinant somatotropin (rBST) various studies have been developed on milk and meat production in farm animals. The objective of this study was to evaluate the effect of rBST on metabolic markers of energetic, protein, mineral and hepatic metabolism, as well as, to evaluate its effect on concentrations of IGF-I, insulin and quality parameters semen in bulls. This study was carried in central of artificial insemination ABS/PECPLAN using 20 bulls of european breeds. These animals were divided in two groups, a group that received a placebo application (NaCl, 0.9%) and another that received rBST (Lactotropin®/Elanco Animal Health). Five blood collections for evaluation of metabolic and hormonal markers and 6 semen collections with posterior freezing for the accomplishment of the corresponding semen evaluations. There was no effect of rBST (P > 0,05) in metabolic markers, except in the concentration of gamma- glutamyltransferase (GGT), that increased in the group that received rBST (P < 0,05), but inside the physiological range, in the hormones evaluations, IGF-I increased in the group treated with rBST (P < 0,05), but there wasn t difference in the insulin concentrations (P > 0,05). In relation to the semen evaluations, there were no differences observed (P > 0,05) in motility and morphology evaluated in the period before freezing. In after freezing evaluations, being that motility, morphology, integrity of plasmatic membrane by fluorescent sounding leads and the hiposmotic test, differences have been observed (P < 0,05) between groups, showing beneficial effect of rBST in these characteristics. In this way can be observed that rBST, beyond raising the IGF-I levels positively influenced the seminal after freezing characteristics evaluated without causing disequilibrium in the metabolism of treated animals since the concentrations of the evaluated metabolic markers were in accordance with the physiological standards for the bovine species. |
publishDate |
2007 |
dc.date.issued.fl_str_mv |
2007-05-07 |
dc.date.available.fl_str_mv |
2009-12-10 2014-08-20T14:37:58Z |
dc.date.accessioned.fl_str_mv |
2014-08-20T14:37:58Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
VIEIRA, Marcelo Brandi. Influence of bovine recombinant somatotropin (rBST) on metabolic parameters, hormones and semen quality of bulls. 2007. 71 f. Dissertação (Mestrado em Veterinária) - Universidade Federal de Pelotas, Pelotas, 2007. |
dc.identifier.uri.fl_str_mv |
http://repositorio.ufpel.edu.br/handle/ri/2541 |
identifier_str_mv |
VIEIRA, Marcelo Brandi. Influence of bovine recombinant somatotropin (rBST) on metabolic parameters, hormones and semen quality of bulls. 2007. 71 f. Dissertação (Mestrado em Veterinária) - Universidade Federal de Pelotas, Pelotas, 2007. |
url |
http://repositorio.ufpel.edu.br/handle/ri/2541 |
dc.language.iso.fl_str_mv |
por |
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por |
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info:eu-repo/semantics/openAccess |
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openAccess |
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Universidade Federal de Pelotas |
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Programa de Pós-Graduação em Veterinária |
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UFPel |
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BR |
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Veterinária |
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Universidade Federal de Pelotas |
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