Influência da somatotropina recombinante bovina (rBST) sobre parâmetros metabólicos, hormonais e de qualidade de sêmen em touros

Detalhes bibliográficos
Autor(a) principal: Vieira, Marcelo Brandi
Data de Publicação: 2007
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Repositório Institucional da UFPel - Guaiaca
Texto Completo: http://repositorio.ufpel.edu.br/handle/ri/2541
Resumo: The growth hormone (GH) have as main function improve proliferation and cellular development, but also participates of processes related to the immune system and reproductive function. The effect of GH is exerted by the IGF-I (insulin-like growth factor I), that is a hormone polypeptidic mitotic secreted by all cells that carry through mitosis. Since the development of the recombinant form of the bovine recombinant somatotropin (rBST) various studies have been developed on milk and meat production in farm animals. The objective of this study was to evaluate the effect of rBST on metabolic markers of energetic, protein, mineral and hepatic metabolism, as well as, to evaluate its effect on concentrations of IGF-I, insulin and quality parameters semen in bulls. This study was carried in central of artificial insemination ABS/PECPLAN using 20 bulls of european breeds. These animals were divided in two groups, a group that received a placebo application (NaCl, 0.9%) and another that received rBST (Lactotropin®/Elanco Animal Health). Five blood collections for evaluation of metabolic and hormonal markers and 6 semen collections with posterior freezing for the accomplishment of the corresponding semen evaluations. There was no effect of rBST (P > 0,05) in metabolic markers, except in the concentration of gamma- glutamyltransferase (GGT), that increased in the group that received rBST (P < 0,05), but inside the physiological range, in the hormones evaluations, IGF-I increased in the group treated with rBST (P < 0,05), but there wasn t difference in the insulin concentrations (P > 0,05). In relation to the semen evaluations, there were no differences observed (P > 0,05) in motility and morphology evaluated in the period before freezing. In after freezing evaluations, being that motility, morphology, integrity of plasmatic membrane by fluorescent sounding leads and the hiposmotic test, differences have been observed (P < 0,05) between groups, showing beneficial effect of rBST in these characteristics. In this way can be observed that rBST, beyond raising the IGF-I levels positively influenced the seminal after freezing characteristics evaluated without causing disequilibrium in the metabolism of treated animals since the concentrations of the evaluated metabolic markers were in accordance with the physiological standards for the bovine species.
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spelling 2014-08-20T14:37:58Z2009-12-102014-08-20T14:37:58Z2007-05-07VIEIRA, Marcelo Brandi. Influence of bovine recombinant somatotropin (rBST) on metabolic parameters, hormones and semen quality of bulls. 2007. 71 f. Dissertação (Mestrado em Veterinária) - Universidade Federal de Pelotas, Pelotas, 2007.http://repositorio.ufpel.edu.br/handle/ri/2541The growth hormone (GH) have as main function improve proliferation and cellular development, but also participates of processes related to the immune system and reproductive function. The effect of GH is exerted by the IGF-I (insulin-like growth factor I), that is a hormone polypeptidic mitotic secreted by all cells that carry through mitosis. Since the development of the recombinant form of the bovine recombinant somatotropin (rBST) various studies have been developed on milk and meat production in farm animals. The objective of this study was to evaluate the effect of rBST on metabolic markers of energetic, protein, mineral and hepatic metabolism, as well as, to evaluate its effect on concentrations of IGF-I, insulin and quality parameters semen in bulls. This study was carried in central of artificial insemination ABS/PECPLAN using 20 bulls of european breeds. These animals were divided in two groups, a group that received a placebo application (NaCl, 0.9%) and another that received rBST (Lactotropin®/Elanco Animal Health). Five blood collections for evaluation of metabolic and hormonal markers and 6 semen collections with posterior freezing for the accomplishment of the corresponding semen evaluations. There was no effect of rBST (P > 0,05) in metabolic markers, except in the concentration of gamma- glutamyltransferase (GGT), that increased in the group that received rBST (P < 0,05), but inside the physiological range, in the hormones evaluations, IGF-I increased in the group treated with rBST (P < 0,05), but there wasn t difference in the insulin concentrations (P > 0,05). In relation to the semen evaluations, there were no differences observed (P > 0,05) in motility and morphology evaluated in the period before freezing. In after freezing evaluations, being that motility, morphology, integrity of plasmatic membrane by fluorescent sounding leads and the hiposmotic test, differences have been observed (P < 0,05) between groups, showing beneficial effect of rBST in these characteristics. In this way can be observed that rBST, beyond raising the IGF-I levels positively influenced the seminal after freezing characteristics evaluated without causing disequilibrium in the metabolism of treated animals since the concentrations of the evaluated metabolic markers were in accordance with the physiological standards for the bovine species.O hormônio do crescimento (GH) possui como principal função realizar a proliferação e desenvolvimento celular, participando também de processos relacionados ao sistema imune e a reprodução. O efeito do GH é exercido pelo IGF-I (fator de crescimento semelhante à insulina I), que é um hormônio polipeptídico mitótico secretado por todas as células que realizam mitose. A partir do desenvolvimento da forma recombinante da somatotropina recombinante bovina (rBST) foram desenvolvidos inúmeros estudos relacionados a produção de leite e carne em animais de produção. O objetivo deste estudo foi avaliar o efeito do rBST sobre marcadores metabólicos relacionados ao metabolismo energético, protéico, mineral e hepático, bem como avaliar o seu efeito nas concentrações de IGF-I, insulina e nos parâmetros de qualidade de sêmen em touros. Este estudo foi realizado na central de inseminação artificial ABS/PECPLAN, com 20 touros de raças predominantemente européias. Estes animais foram divididos em dois grupos, sendo que um grupo recebeu a aplicação do placebo (solução fisiológica, NaCl 0,9%) e outro rBST (Lactotropin®/Elanco Saúde Animal). Foram realizados 5 coletas de sangue para avaliação dos marcadores metabólicos e hormonais e 6 coletas de sêmen com posterior congelamento para a realização das correspondentes avaliações de sêmen. De acordo com os resultados não foi observado (P > 0,05) efeito do rBST nas avaliações dos marcadores metabólicos, exceto nas concentrações da enzima hepática gama - glutamiltransferase (GGT), que foi mais elevada no grupo que recebeu o rBST (P < 0,05), mas de acordo com os padrões fisiológicos. Nas avaliações hormonais os níveis de IGF-I foram mais elevados no grupo tratado com rBST (P < 0,05), não sendo, porém, observadas diferenças para os níveis de insulina (P > 0,05). Em relação às avaliações de sêmen, não foram observadas diferenças entre os dois grupos (P > 0,05) na motilidade e morfologia espermática avaliadas no período pré-congelamento. Nas avaliações pós-congelamento que incluíam a motilidade, morfologia, integridade de membrana plasmática por sondas fluorescentes e pelo teste hiposmótico foram observadas diferenças (P < 0,05) entre os grupos, sendo demonstrado melhores índices no grupo que recebeu o tratamento com rBST. Desta forma pode-se observar que o rBST, além de elevar o níveis de IGF-I, influenciou positivamente as características seminais avaliadas no pós-congelamento sem que tivesse ocasionado desequilíbrio no metabolismo dos animais tratados, já que as concentrações dos marcadores metabólicos avaliados estavam de acordo com os padrões fisiológicos para a espécie bovina.application/pdfporUniversidade Federal de PelotasPrograma de Pós-Graduação em VeterináriaUFPelBRVeterináriaVeterináriaMetabolismoTourosrBSTReproduçãoBullsMetabolismrBSTReproductionCNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIAInfluência da somatotropina recombinante bovina (rBST) sobre parâmetros metabólicos, hormonais e de qualidade de sêmen em tourosInfluence of bovine recombinant somatotropin (rBST) on metabolic parameters, hormones and semen quality of bullsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesishttp://lattes.cnpq.br/3324076914071687http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4796653E9Corrêa, Márcio NunesVieira, Marcelo Brandiinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFPel - Guaiacainstname:Universidade Federal de Pelotas (UFPEL)instacron:UFPELORIGINALdissertacao_marcelo_vieira.pdfapplication/pdf644753http://guaiaca.ufpel.edu.br/xmlui/bitstream/123456789/2541/1/dissertacao_marcelo_vieira.pdfe45dacce2e978ab7c293923a447f7290MD51open accessTEXTdissertacao_marcelo_vieira.pdf.txtdissertacao_marcelo_vieira.pdf.txtExtracted Texttext/plain114618http://guaiaca.ufpel.edu.br/xmlui/bitstream/123456789/2541/2/dissertacao_marcelo_vieira.pdf.txt5675d6da64d23528e21e71df32976d45MD52open accessTHUMBNAILdissertacao_marcelo_vieira.pdf.jpgdissertacao_marcelo_vieira.pdf.jpgGenerated Thumbnailimage/jpeg1696http://guaiaca.ufpel.edu.br/xmlui/bitstream/123456789/2541/3/dissertacao_marcelo_vieira.pdf.jpgd6fa745f0fea82a2fa4fd9b1c9b31a14MD53open access123456789/25412019-09-13 09:57:08.986open accessoai:guaiaca.ufpel.edu.br:123456789/2541Repositório InstitucionalPUBhttp://repositorio.ufpel.edu.br/oai/requestrippel@ufpel.edu.br || repositorio@ufpel.edu.br || aline.batista@ufpel.edu.bropendoar:2019-09-13T12:57:08Repositório Institucional da UFPel - Guaiaca - Universidade Federal de Pelotas (UFPEL)false
dc.title.por.fl_str_mv Influência da somatotropina recombinante bovina (rBST) sobre parâmetros metabólicos, hormonais e de qualidade de sêmen em touros
dc.title.alternative.eng.fl_str_mv Influence of bovine recombinant somatotropin (rBST) on metabolic parameters, hormones and semen quality of bulls
title Influência da somatotropina recombinante bovina (rBST) sobre parâmetros metabólicos, hormonais e de qualidade de sêmen em touros
spellingShingle Influência da somatotropina recombinante bovina (rBST) sobre parâmetros metabólicos, hormonais e de qualidade de sêmen em touros
Vieira, Marcelo Brandi
Veterinária
Metabolismo
Touros
rBST
Reprodução
Bulls
Metabolism
rBST
Reproduction
CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA
title_short Influência da somatotropina recombinante bovina (rBST) sobre parâmetros metabólicos, hormonais e de qualidade de sêmen em touros
title_full Influência da somatotropina recombinante bovina (rBST) sobre parâmetros metabólicos, hormonais e de qualidade de sêmen em touros
title_fullStr Influência da somatotropina recombinante bovina (rBST) sobre parâmetros metabólicos, hormonais e de qualidade de sêmen em touros
title_full_unstemmed Influência da somatotropina recombinante bovina (rBST) sobre parâmetros metabólicos, hormonais e de qualidade de sêmen em touros
title_sort Influência da somatotropina recombinante bovina (rBST) sobre parâmetros metabólicos, hormonais e de qualidade de sêmen em touros
author Vieira, Marcelo Brandi
author_facet Vieira, Marcelo Brandi
author_role author
dc.contributor.authorLattes.por.fl_str_mv http://lattes.cnpq.br/3324076914071687
dc.contributor.advisorLattes.por.fl_str_mv http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4796653E9
dc.contributor.advisor1.fl_str_mv Corrêa, Márcio Nunes
dc.contributor.author.fl_str_mv Vieira, Marcelo Brandi
contributor_str_mv Corrêa, Márcio Nunes
dc.subject.por.fl_str_mv Veterinária
Metabolismo
Touros
rBST
Reprodução
topic Veterinária
Metabolismo
Touros
rBST
Reprodução
Bulls
Metabolism
rBST
Reproduction
CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA
dc.subject.eng.fl_str_mv Bulls
Metabolism
rBST
Reproduction
dc.subject.cnpq.fl_str_mv CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA
description The growth hormone (GH) have as main function improve proliferation and cellular development, but also participates of processes related to the immune system and reproductive function. The effect of GH is exerted by the IGF-I (insulin-like growth factor I), that is a hormone polypeptidic mitotic secreted by all cells that carry through mitosis. Since the development of the recombinant form of the bovine recombinant somatotropin (rBST) various studies have been developed on milk and meat production in farm animals. The objective of this study was to evaluate the effect of rBST on metabolic markers of energetic, protein, mineral and hepatic metabolism, as well as, to evaluate its effect on concentrations of IGF-I, insulin and quality parameters semen in bulls. This study was carried in central of artificial insemination ABS/PECPLAN using 20 bulls of european breeds. These animals were divided in two groups, a group that received a placebo application (NaCl, 0.9%) and another that received rBST (Lactotropin®/Elanco Animal Health). Five blood collections for evaluation of metabolic and hormonal markers and 6 semen collections with posterior freezing for the accomplishment of the corresponding semen evaluations. There was no effect of rBST (P > 0,05) in metabolic markers, except in the concentration of gamma- glutamyltransferase (GGT), that increased in the group that received rBST (P < 0,05), but inside the physiological range, in the hormones evaluations, IGF-I increased in the group treated with rBST (P < 0,05), but there wasn t difference in the insulin concentrations (P > 0,05). In relation to the semen evaluations, there were no differences observed (P > 0,05) in motility and morphology evaluated in the period before freezing. In after freezing evaluations, being that motility, morphology, integrity of plasmatic membrane by fluorescent sounding leads and the hiposmotic test, differences have been observed (P < 0,05) between groups, showing beneficial effect of rBST in these characteristics. In this way can be observed that rBST, beyond raising the IGF-I levels positively influenced the seminal after freezing characteristics evaluated without causing disequilibrium in the metabolism of treated animals since the concentrations of the evaluated metabolic markers were in accordance with the physiological standards for the bovine species.
publishDate 2007
dc.date.issued.fl_str_mv 2007-05-07
dc.date.available.fl_str_mv 2009-12-10
2014-08-20T14:37:58Z
dc.date.accessioned.fl_str_mv 2014-08-20T14:37:58Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
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dc.identifier.citation.fl_str_mv VIEIRA, Marcelo Brandi. Influence of bovine recombinant somatotropin (rBST) on metabolic parameters, hormones and semen quality of bulls. 2007. 71 f. Dissertação (Mestrado em Veterinária) - Universidade Federal de Pelotas, Pelotas, 2007.
dc.identifier.uri.fl_str_mv http://repositorio.ufpel.edu.br/handle/ri/2541
identifier_str_mv VIEIRA, Marcelo Brandi. Influence of bovine recombinant somatotropin (rBST) on metabolic parameters, hormones and semen quality of bulls. 2007. 71 f. Dissertação (Mestrado em Veterinária) - Universidade Federal de Pelotas, Pelotas, 2007.
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