Invasive carcinoma, carcinoma in situ, and atypical ductal hyperplasia: correlation of histopathological findings of breast biopsy and surgery
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Clinical and Biomedical Research |
Texto Completo: | https://seer.ufrgs.br/index.php/hcpa/article/view/125725 |
Resumo: | OBJECTIVE: To compare the histopathological findings of carcinoma and atypical hyperplasia obtained with breast biopsy and the respective surgical procedures.MATERIAL AND METHODS: 527 breast biopsies were carried out at our services within an 18-month period. Out of these biopsies, 118 were diagnosed as carcinoma in situ or invasive carcinoma and atypical hyperplasia. Diagnosis was obtained with digital stereotactic breast biopsy. Patients presented asymptomatic, had subclinical lesions on mammographic screening, averaged 55 years of age, and were, in their majority, postmenopausal women.RESULTS: Out of the 118 patients who fulfilled our study criteria, we were able to establish a comparison with the histopathological findings of surgical biopsy in 73 cases (61,9%). There was a loss of follow up in 45 cases (38,1 %). The histopathological findings were compatible with those of breast biopsy in 60 cases (82%), both in relationto the type and histopathological grade of the lesion.CONCLUSIONS: Breast biopsy represents an important alternative to surgical biopsy for the diagnosis of nonpalpable breast lesions. It is a rapid, easy to operate methodthat provides optimal results. In addition, its results presented a good rate of agreement with the histopathological findings of surgical biopsy. The quality of the collected material was considered satisfactory for the purpose of diagnosis. |
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Invasive carcinoma, carcinoma in situ, and atypical ductal hyperplasia: correlation of histopathological findings of breast biopsy and surgeryCarcinoma invasor, carcinoma in situ e hiperplasia epitelial ductal atípica: correlação dos achados histopatológicos entre mamotomia e cirurgiaBiópsia das mamasneoplasmo das mamasdiagnósticocirurgia de mamasBreast biopsybreast neoplasmdiagnosisbreast surgeryOBJECTIVE: To compare the histopathological findings of carcinoma and atypical hyperplasia obtained with breast biopsy and the respective surgical procedures.MATERIAL AND METHODS: 527 breast biopsies were carried out at our services within an 18-month period. Out of these biopsies, 118 were diagnosed as carcinoma in situ or invasive carcinoma and atypical hyperplasia. Diagnosis was obtained with digital stereotactic breast biopsy. Patients presented asymptomatic, had subclinical lesions on mammographic screening, averaged 55 years of age, and were, in their majority, postmenopausal women.RESULTS: Out of the 118 patients who fulfilled our study criteria, we were able to establish a comparison with the histopathological findings of surgical biopsy in 73 cases (61,9%). There was a loss of follow up in 45 cases (38,1 %). The histopathological findings were compatible with those of breast biopsy in 60 cases (82%), both in relationto the type and histopathological grade of the lesion.CONCLUSIONS: Breast biopsy represents an important alternative to surgical biopsy for the diagnosis of nonpalpable breast lesions. It is a rapid, easy to operate methodthat provides optimal results. In addition, its results presented a good rate of agreement with the histopathological findings of surgical biopsy. The quality of the collected material was considered satisfactory for the purpose of diagnosis. OBJETIVO: Comparar os resultados histopatológicos de carcinoma e hiperplasia atípica obtidos através da mamotomia com os das respectivas biópsias cirúrgicas.MATERIAIS E MÉTODOS: Foram realizadas nesta instituição 527 mamotomias em 18 meses. Destas, 118 tiveram diagnóstico de carcinoma in situ ou invasor e hiperplasia atípica, através da mamotomia guiada por estereotaxia digital. As pacientes eram assintomáticas, apresentando lesão subclínica ao rastreio mamográfico. A idade média destas pacientes era de 55 anos e a maioria encontrava-se na pós-menopausa.RESULTADOS: Das 118 pacientes que preencheram os critérios para este estudo, foi possível realizar a comparação com os resultados histopatológicos da biópsia cirúrgica em 73 casos (61,9%). Em 45 casos houve perda de follow up (38,1%). O laudo histopatológico pós-cirúrgico foi compatível com o da mamotomia em 60 casos (82%), tanto em relação ao tipo quanto ao grau histopatológico da lesão.CONCLUSÃO: A mamotomia tem representado uma importante alternativa à biópsia cirúrgica para o diagnóstico das lesões impalpáveis da mama. Trata-se de um método rápido, de fácil realização, com ótimos resultados, além de apresentar boa taxa de concordância com os resultados histopatológicos obtidos através da biópsia cirúrgica. A qualidade do material obtido tem sido considerada satisfatória para o diagnóstico.HCPA/FAMED/UFRGS2022-07-18info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed ArticleAvaliado por Paresapplication/pdfhttps://seer.ufrgs.br/index.php/hcpa/article/view/125725Clinical & Biomedical Research; Vol. 21 No. 2 (2001): Revista HCPAClinical and Biomedical Research; v. 21 n. 2 (2001): Revista HCPA2357-9730reponame:Clinical and Biomedical Researchinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSporhttps://seer.ufrgs.br/index.php/hcpa/article/view/125725/85383http://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccess A. P. Pasqualette, Henrique M. S. Pereira, Paulo J. G. Calas, Maria V. P. Dutra, Maria de Castro, Rosana Caldoncelli, Valeska R. Manoel, Vânia2022-07-18T19:41:14Zoai:seer.ufrgs.br:article/125725Revistahttps://www.seer.ufrgs.br/index.php/hcpaPUBhttps://seer.ufrgs.br/index.php/hcpa/oai||cbr@hcpa.edu.br2357-97302357-9730opendoar:2022-07-18T19:41:14Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.none.fl_str_mv |
Invasive carcinoma, carcinoma in situ, and atypical ductal hyperplasia: correlation of histopathological findings of breast biopsy and surgery Carcinoma invasor, carcinoma in situ e hiperplasia epitelial ductal atípica: correlação dos achados histopatológicos entre mamotomia e cirurgia |
title |
Invasive carcinoma, carcinoma in situ, and atypical ductal hyperplasia: correlation of histopathological findings of breast biopsy and surgery |
spellingShingle |
Invasive carcinoma, carcinoma in situ, and atypical ductal hyperplasia: correlation of histopathological findings of breast biopsy and surgery A. P. Pasqualette, Henrique Biópsia das mamas neoplasmo das mamas diagnóstico cirurgia de mamas Breast biopsy breast neoplasm diagnosis breast surgery |
title_short |
Invasive carcinoma, carcinoma in situ, and atypical ductal hyperplasia: correlation of histopathological findings of breast biopsy and surgery |
title_full |
Invasive carcinoma, carcinoma in situ, and atypical ductal hyperplasia: correlation of histopathological findings of breast biopsy and surgery |
title_fullStr |
Invasive carcinoma, carcinoma in situ, and atypical ductal hyperplasia: correlation of histopathological findings of breast biopsy and surgery |
title_full_unstemmed |
Invasive carcinoma, carcinoma in situ, and atypical ductal hyperplasia: correlation of histopathological findings of breast biopsy and surgery |
title_sort |
Invasive carcinoma, carcinoma in situ, and atypical ductal hyperplasia: correlation of histopathological findings of breast biopsy and surgery |
author |
A. P. Pasqualette, Henrique |
author_facet |
A. P. Pasqualette, Henrique M. S. Pereira, Paulo J. G. Calas, Maria V. P. Dutra, Maria de Castro, Rosana Caldoncelli, Valeska R. Manoel, Vânia |
author_role |
author |
author2 |
M. S. Pereira, Paulo J. G. Calas, Maria V. P. Dutra, Maria de Castro, Rosana Caldoncelli, Valeska R. Manoel, Vânia |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
A. P. Pasqualette, Henrique M. S. Pereira, Paulo J. G. Calas, Maria V. P. Dutra, Maria de Castro, Rosana Caldoncelli, Valeska R. Manoel, Vânia |
dc.subject.por.fl_str_mv |
Biópsia das mamas neoplasmo das mamas diagnóstico cirurgia de mamas Breast biopsy breast neoplasm diagnosis breast surgery |
topic |
Biópsia das mamas neoplasmo das mamas diagnóstico cirurgia de mamas Breast biopsy breast neoplasm diagnosis breast surgery |
description |
OBJECTIVE: To compare the histopathological findings of carcinoma and atypical hyperplasia obtained with breast biopsy and the respective surgical procedures.MATERIAL AND METHODS: 527 breast biopsies were carried out at our services within an 18-month period. Out of these biopsies, 118 were diagnosed as carcinoma in situ or invasive carcinoma and atypical hyperplasia. Diagnosis was obtained with digital stereotactic breast biopsy. Patients presented asymptomatic, had subclinical lesions on mammographic screening, averaged 55 years of age, and were, in their majority, postmenopausal women.RESULTS: Out of the 118 patients who fulfilled our study criteria, we were able to establish a comparison with the histopathological findings of surgical biopsy in 73 cases (61,9%). There was a loss of follow up in 45 cases (38,1 %). The histopathological findings were compatible with those of breast biopsy in 60 cases (82%), both in relationto the type and histopathological grade of the lesion.CONCLUSIONS: Breast biopsy represents an important alternative to surgical biopsy for the diagnosis of nonpalpable breast lesions. It is a rapid, easy to operate methodthat provides optimal results. In addition, its results presented a good rate of agreement with the histopathological findings of surgical biopsy. The quality of the collected material was considered satisfactory for the purpose of diagnosis. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-07-18 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article Avaliado por Pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://seer.ufrgs.br/index.php/hcpa/article/view/125725 |
url |
https://seer.ufrgs.br/index.php/hcpa/article/view/125725 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://seer.ufrgs.br/index.php/hcpa/article/view/125725/85383 |
dc.rights.driver.fl_str_mv |
http://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
http://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
HCPA/FAMED/UFRGS |
publisher.none.fl_str_mv |
HCPA/FAMED/UFRGS |
dc.source.none.fl_str_mv |
Clinical & Biomedical Research; Vol. 21 No. 2 (2001): Revista HCPA Clinical and Biomedical Research; v. 21 n. 2 (2001): Revista HCPA 2357-9730 reponame:Clinical and Biomedical Research instname:Universidade Federal do Rio Grande do Sul (UFRGS) instacron:UFRGS |
instname_str |
Universidade Federal do Rio Grande do Sul (UFRGS) |
instacron_str |
UFRGS |
institution |
UFRGS |
reponame_str |
Clinical and Biomedical Research |
collection |
Clinical and Biomedical Research |
repository.name.fl_str_mv |
Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS) |
repository.mail.fl_str_mv |
||cbr@hcpa.edu.br |
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1799767057428905984 |