Invasive carcinoma, carcinoma in situ, and atypical ductal hyperplasia: correlation of histopathological findings of breast biopsy and surgery

Detalhes bibliográficos
Autor(a) principal: A. P. Pasqualette, Henrique
Data de Publicação: 2022
Outros Autores: M. S. Pereira, Paulo, J. G. Calas, Maria, V. P. Dutra, Maria, de Castro, Rosana, Caldoncelli, Valeska, R. Manoel, Vânia
Tipo de documento: Artigo
Idioma: por
Título da fonte: Clinical and Biomedical Research
Texto Completo: https://seer.ufrgs.br/index.php/hcpa/article/view/125725
Resumo: OBJECTIVE: To compare the histopathological findings of carcinoma and atypical hyperplasia obtained with breast biopsy and the respective surgical procedures.MATERIAL AND METHODS: 527 breast biopsies were carried out at our services within an 18-month period. Out of these biopsies, 118 were diagnosed as carcinoma in situ or invasive carcinoma and atypical hyperplasia. Diagnosis was obtained with digital stereotactic breast biopsy. Patients presented asymptomatic, had subclinical lesions on mammographic screening, averaged 55 years of age, and were, in their majority, postmenopausal women.RESULTS: Out of the 118 patients who fulfilled our study criteria, we were able to establish a comparison with the histopathological findings of surgical biopsy in 73 cases (61,9%). There was a loss of follow up in 45 cases (38,1 %). The histopathological findings were compatible with those of breast biopsy in 60 cases (82%), both in relationto the type and histopathological grade of the lesion.CONCLUSIONS: Breast biopsy represents an important alternative to surgical biopsy for the diagnosis of nonpalpable breast lesions. It is a rapid, easy to operate methodthat provides optimal results. In addition, its results presented a good rate of agreement with the histopathological findings of surgical biopsy. The quality of the collected material was considered satisfactory for the purpose of diagnosis. 
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spelling Invasive carcinoma, carcinoma in situ, and atypical ductal hyperplasia: correlation of histopathological findings of breast biopsy and surgeryCarcinoma invasor, carcinoma in situ e hiperplasia epitelial ductal atípica: correlação dos achados histopatológicos entre mamotomia e cirurgiaBiópsia das mamasneoplasmo das mamasdiagnósticocirurgia de mamasBreast biopsybreast neoplasmdiagnosisbreast surgeryOBJECTIVE: To compare the histopathological findings of carcinoma and atypical hyperplasia obtained with breast biopsy and the respective surgical procedures.MATERIAL AND METHODS: 527 breast biopsies were carried out at our services within an 18-month period. Out of these biopsies, 118 were diagnosed as carcinoma in situ or invasive carcinoma and atypical hyperplasia. Diagnosis was obtained with digital stereotactic breast biopsy. Patients presented asymptomatic, had subclinical lesions on mammographic screening, averaged 55 years of age, and were, in their majority, postmenopausal women.RESULTS: Out of the 118 patients who fulfilled our study criteria, we were able to establish a comparison with the histopathological findings of surgical biopsy in 73 cases (61,9%). There was a loss of follow up in 45 cases (38,1 %). The histopathological findings were compatible with those of breast biopsy in 60 cases (82%), both in relationto the type and histopathological grade of the lesion.CONCLUSIONS: Breast biopsy represents an important alternative to surgical biopsy for the diagnosis of nonpalpable breast lesions. It is a rapid, easy to operate methodthat provides optimal results. In addition, its results presented a good rate of agreement with the histopathological findings of surgical biopsy. The quality of the collected material was considered satisfactory for the purpose of diagnosis. OBJETIVO: Comparar os resultados histopatológicos de carcinoma e hiperplasia atípica obtidos através da mamotomia com os das respectivas biópsias cirúrgicas.MATERIAIS E MÉTODOS: Foram realizadas nesta instituição 527 mamotomias em 18 meses. Destas, 118 tiveram diagnóstico de carcinoma in situ ou invasor e hiperplasia atípica, através da mamotomia guiada por estereotaxia digital. As pacientes eram assintomáticas, apresentando lesão subclínica ao rastreio mamográfico. A idade média destas pacientes era de 55 anos e a maioria encontrava-se na pós-menopausa.RESULTADOS: Das 118 pacientes que preencheram os critérios para este estudo, foi possível realizar a comparação com os resultados histopatológicos da biópsia cirúrgica em 73 casos (61,9%). Em 45 casos houve perda de follow up (38,1%). O laudo histopatológico pós-cirúrgico foi compatível com o da mamotomia em 60 casos (82%), tanto em relação ao tipo quanto ao grau histopatológico da lesão.CONCLUSÃO: A mamotomia tem representado uma importante alternativa à biópsia cirúrgica para o diagnóstico das lesões impalpáveis da mama. Trata-se de um método rápido, de fácil realização, com ótimos resultados, além de apresentar boa taxa de concordância com os resultados histopatológicos obtidos através da biópsia cirúrgica. A qualidade do material obtido tem sido considerada satisfatória para o diagnóstico.HCPA/FAMED/UFRGS2022-07-18info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed ArticleAvaliado por Paresapplication/pdfhttps://seer.ufrgs.br/index.php/hcpa/article/view/125725Clinical & Biomedical Research; Vol. 21 No. 2 (2001): Revista HCPAClinical and Biomedical Research; v. 21 n. 2 (2001): Revista HCPA2357-9730reponame:Clinical and Biomedical Researchinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSporhttps://seer.ufrgs.br/index.php/hcpa/article/view/125725/85383http://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccess A. P. Pasqualette, Henrique M. S. Pereira, Paulo J. G. Calas, Maria V. P. Dutra, Maria de Castro, Rosana Caldoncelli, Valeska R. Manoel, Vânia2022-07-18T19:41:14Zoai:seer.ufrgs.br:article/125725Revistahttps://www.seer.ufrgs.br/index.php/hcpaPUBhttps://seer.ufrgs.br/index.php/hcpa/oai||cbr@hcpa.edu.br2357-97302357-9730opendoar:2022-07-18T19:41:14Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.none.fl_str_mv Invasive carcinoma, carcinoma in situ, and atypical ductal hyperplasia: correlation of histopathological findings of breast biopsy and surgery
Carcinoma invasor, carcinoma in situ e hiperplasia epitelial ductal atípica: correlação dos achados histopatológicos entre mamotomia e cirurgia
title Invasive carcinoma, carcinoma in situ, and atypical ductal hyperplasia: correlation of histopathological findings of breast biopsy and surgery
spellingShingle Invasive carcinoma, carcinoma in situ, and atypical ductal hyperplasia: correlation of histopathological findings of breast biopsy and surgery
A. P. Pasqualette, Henrique
Biópsia das mamas
neoplasmo das mamas
diagnóstico
cirurgia de mamas
Breast biopsy
breast neoplasm
diagnosis
breast surgery
title_short Invasive carcinoma, carcinoma in situ, and atypical ductal hyperplasia: correlation of histopathological findings of breast biopsy and surgery
title_full Invasive carcinoma, carcinoma in situ, and atypical ductal hyperplasia: correlation of histopathological findings of breast biopsy and surgery
title_fullStr Invasive carcinoma, carcinoma in situ, and atypical ductal hyperplasia: correlation of histopathological findings of breast biopsy and surgery
title_full_unstemmed Invasive carcinoma, carcinoma in situ, and atypical ductal hyperplasia: correlation of histopathological findings of breast biopsy and surgery
title_sort Invasive carcinoma, carcinoma in situ, and atypical ductal hyperplasia: correlation of histopathological findings of breast biopsy and surgery
author A. P. Pasqualette, Henrique
author_facet A. P. Pasqualette, Henrique
M. S. Pereira, Paulo
J. G. Calas, Maria
V. P. Dutra, Maria
de Castro, Rosana
Caldoncelli, Valeska
R. Manoel, Vânia
author_role author
author2 M. S. Pereira, Paulo
J. G. Calas, Maria
V. P. Dutra, Maria
de Castro, Rosana
Caldoncelli, Valeska
R. Manoel, Vânia
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv A. P. Pasqualette, Henrique
M. S. Pereira, Paulo
J. G. Calas, Maria
V. P. Dutra, Maria
de Castro, Rosana
Caldoncelli, Valeska
R. Manoel, Vânia
dc.subject.por.fl_str_mv Biópsia das mamas
neoplasmo das mamas
diagnóstico
cirurgia de mamas
Breast biopsy
breast neoplasm
diagnosis
breast surgery
topic Biópsia das mamas
neoplasmo das mamas
diagnóstico
cirurgia de mamas
Breast biopsy
breast neoplasm
diagnosis
breast surgery
description OBJECTIVE: To compare the histopathological findings of carcinoma and atypical hyperplasia obtained with breast biopsy and the respective surgical procedures.MATERIAL AND METHODS: 527 breast biopsies were carried out at our services within an 18-month period. Out of these biopsies, 118 were diagnosed as carcinoma in situ or invasive carcinoma and atypical hyperplasia. Diagnosis was obtained with digital stereotactic breast biopsy. Patients presented asymptomatic, had subclinical lesions on mammographic screening, averaged 55 years of age, and were, in their majority, postmenopausal women.RESULTS: Out of the 118 patients who fulfilled our study criteria, we were able to establish a comparison with the histopathological findings of surgical biopsy in 73 cases (61,9%). There was a loss of follow up in 45 cases (38,1 %). The histopathological findings were compatible with those of breast biopsy in 60 cases (82%), both in relationto the type and histopathological grade of the lesion.CONCLUSIONS: Breast biopsy represents an important alternative to surgical biopsy for the diagnosis of nonpalpable breast lesions. It is a rapid, easy to operate methodthat provides optimal results. In addition, its results presented a good rate of agreement with the histopathological findings of surgical biopsy. The quality of the collected material was considered satisfactory for the purpose of diagnosis. 
publishDate 2022
dc.date.none.fl_str_mv 2022-07-18
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
Avaliado por Pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://seer.ufrgs.br/index.php/hcpa/article/view/125725
url https://seer.ufrgs.br/index.php/hcpa/article/view/125725
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://seer.ufrgs.br/index.php/hcpa/article/view/125725/85383
dc.rights.driver.fl_str_mv http://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv HCPA/FAMED/UFRGS
publisher.none.fl_str_mv HCPA/FAMED/UFRGS
dc.source.none.fl_str_mv Clinical & Biomedical Research; Vol. 21 No. 2 (2001): Revista HCPA
Clinical and Biomedical Research; v. 21 n. 2 (2001): Revista HCPA
2357-9730
reponame:Clinical and Biomedical Research
instname:Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
instname_str Universidade Federal do Rio Grande do Sul (UFRGS)
instacron_str UFRGS
institution UFRGS
reponame_str Clinical and Biomedical Research
collection Clinical and Biomedical Research
repository.name.fl_str_mv Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)
repository.mail.fl_str_mv ||cbr@hcpa.edu.br
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