Losartan-Induced Acute Interstitial Nephritis

Detalhes bibliográficos
Autor(a) principal: Weinert, Letícia Schwerz
Data de Publicação: 2007
Outros Autores: Triches, Cristina Bergmann, Leitão, Cristiane Bauermann, Miltersteiner, Diego, Costa, Cezar Amauri Ribeiro da, Balbinotto, Antônio, Silveiro, Sandra Pinho, Gross, Jorge Luiz
Tipo de documento: Artigo
Idioma: por
Título da fonte: Clinical and Biomedical Research
Texto Completo: https://seer.ufrgs.br/index.php/hcpa/article/view/463
Resumo: Acute interstitial nephritis is an important cause of acute renal failure. The majority of cases results from exposure to drugs. How-ever imune-mediated injury and infection are common causes. The angiotensin-converting enzyme inhibitors have been implicated as possible etiologic agents, but we could not find previous data of acute intestitial nephritis associated with losartan exposure. We report a case of acute renal failure after losartan exposure, in a patient with diabetic nephropathy. The final diagnosis was confirmed by renal biopsy: acute interstitial nephritis.
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spelling Losartan-Induced Acute Interstitial NephritisNefrite Intersticial Aguda Após Exposição a LosartanNefrite Intersticial AgudaLosartanNefropatia DiabéticaInsuficiência Renal AgudaAcute interstitial nephritis is an important cause of acute renal failure. The majority of cases results from exposure to drugs. How-ever imune-mediated injury and infection are common causes. The angiotensin-converting enzyme inhibitors have been implicated as possible etiologic agents, but we could not find previous data of acute intestitial nephritis associated with losartan exposure. We report a case of acute renal failure after losartan exposure, in a patient with diabetic nephropathy. The final diagnosis was confirmed by renal biopsy: acute interstitial nephritis.Nefrite intersticial aguda é uma causa comum de perda aguda de função renal. Exposição a drogas é o fator desencadeante mais freqüentemente relatado, porém auto-imunidade e infecções também estão associadas. Os inibidores da enzima de conversão da angiotensina têm sido relatados como possíveis agentes, porém não há relato na literatura de nefrite intersticial com uso de losartan. Descrevemos então, o caso de perda aguda de função renal após exposição a losartan, em paciente com dano renal prévio por nefropatia diabética, cuja biópsia renal diagnosticou nefrite intersticial aguda.HCPA/FAMED/UFRGS2007-07-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed ArticleAvaliado por paresapplication/pdfhttps://seer.ufrgs.br/index.php/hcpa/article/view/463Clinical & Biomedical Research; Vol. 27 No. 1 (2007): Revista HCPAClinical and Biomedical Research; v. 27 n. 1 (2007): Revista HCPA2357-9730reponame:Clinical and Biomedical Researchinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSporhttps://seer.ufrgs.br/index.php/hcpa/article/view/463/825Weinert, Letícia SchwerzTriches, Cristina BergmannLeitão, Cristiane BauermannMiltersteiner, DiegoCosta, Cezar Amauri Ribeiro daBalbinotto, AntônioSilveiro, Sandra PinhoGross, Jorge Luizinfo:eu-repo/semantics/openAccess2020-01-16T16:08:11Zoai:seer.ufrgs.br:article/463Revistahttps://www.seer.ufrgs.br/index.php/hcpaPUBhttps://seer.ufrgs.br/index.php/hcpa/oai||cbr@hcpa.edu.br2357-97302357-9730opendoar:2020-01-16T16:08:11Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.none.fl_str_mv Losartan-Induced Acute Interstitial Nephritis
Nefrite Intersticial Aguda Após Exposição a Losartan
title Losartan-Induced Acute Interstitial Nephritis
spellingShingle Losartan-Induced Acute Interstitial Nephritis
Weinert, Letícia Schwerz
Nefrite Intersticial Aguda
Losartan
Nefropatia Diabética
Insuficiência Renal Aguda
title_short Losartan-Induced Acute Interstitial Nephritis
title_full Losartan-Induced Acute Interstitial Nephritis
title_fullStr Losartan-Induced Acute Interstitial Nephritis
title_full_unstemmed Losartan-Induced Acute Interstitial Nephritis
title_sort Losartan-Induced Acute Interstitial Nephritis
author Weinert, Letícia Schwerz
author_facet Weinert, Letícia Schwerz
Triches, Cristina Bergmann
Leitão, Cristiane Bauermann
Miltersteiner, Diego
Costa, Cezar Amauri Ribeiro da
Balbinotto, Antônio
Silveiro, Sandra Pinho
Gross, Jorge Luiz
author_role author
author2 Triches, Cristina Bergmann
Leitão, Cristiane Bauermann
Miltersteiner, Diego
Costa, Cezar Amauri Ribeiro da
Balbinotto, Antônio
Silveiro, Sandra Pinho
Gross, Jorge Luiz
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Weinert, Letícia Schwerz
Triches, Cristina Bergmann
Leitão, Cristiane Bauermann
Miltersteiner, Diego
Costa, Cezar Amauri Ribeiro da
Balbinotto, Antônio
Silveiro, Sandra Pinho
Gross, Jorge Luiz
dc.subject.por.fl_str_mv Nefrite Intersticial Aguda
Losartan
Nefropatia Diabética
Insuficiência Renal Aguda
topic Nefrite Intersticial Aguda
Losartan
Nefropatia Diabética
Insuficiência Renal Aguda
description Acute interstitial nephritis is an important cause of acute renal failure. The majority of cases results from exposure to drugs. How-ever imune-mediated injury and infection are common causes. The angiotensin-converting enzyme inhibitors have been implicated as possible etiologic agents, but we could not find previous data of acute intestitial nephritis associated with losartan exposure. We report a case of acute renal failure after losartan exposure, in a patient with diabetic nephropathy. The final diagnosis was confirmed by renal biopsy: acute interstitial nephritis.
publishDate 2007
dc.date.none.fl_str_mv 2007-07-03
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
Avaliado por pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://seer.ufrgs.br/index.php/hcpa/article/view/463
url https://seer.ufrgs.br/index.php/hcpa/article/view/463
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://seer.ufrgs.br/index.php/hcpa/article/view/463/825
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv HCPA/FAMED/UFRGS
publisher.none.fl_str_mv HCPA/FAMED/UFRGS
dc.source.none.fl_str_mv Clinical & Biomedical Research; Vol. 27 No. 1 (2007): Revista HCPA
Clinical and Biomedical Research; v. 27 n. 1 (2007): Revista HCPA
2357-9730
reponame:Clinical and Biomedical Research
instname:Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
instname_str Universidade Federal do Rio Grande do Sul (UFRGS)
instacron_str UFRGS
institution UFRGS
reponame_str Clinical and Biomedical Research
collection Clinical and Biomedical Research
repository.name.fl_str_mv Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)
repository.mail.fl_str_mv ||cbr@hcpa.edu.br
_version_ 1799767051167858688

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