Incidence and risk factors associated with non-invasive ventilation failure in pediatric patients
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Clinical and Biomedical Research |
Texto Completo: | https://seer.ufrgs.br/index.php/hcpa/article/view/112032 |
Resumo: | Objective: To determine the risk factors associated with failure in noninvasive mechanical ventilation (NIV) in a pediatric intensive care unit. Methods: Retrospective cohort from medical records of patients admitted to the Pediatric ICU of a Hospital in Caxias do Sul, between May 2017 and October 2019, who used NIV. Results: The incidence of NIV failure was 33%. Asthma patients, post-extubation use, continuous use, closure at night, final SIMV modality, ventilatory parameters, initial PEEP, and final FIO2 were also associated with failure. In vital signs, the initial SBP and the final RF were significant. After multivariate analysis, final SIMV modality, closing at night, final PIP, and final RF were associated with NIV failure. Conclusion: SIMV final ventilatory modality, as well as NIV closure at night, higher final PIP and higher final RF are risk factors for NIV failure. |
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Clinical and Biomedical Research |
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Incidence and risk factors associated with non-invasive ventilation failure in pediatric patientsIncidência e fatores de risco associados à falha na ventilação não invasiva em pacientes pediátricosRisk factorsNoninvasive ventilationPediatric Intensive Care UnitRespiratory failureMechanical ventilationPositive-pressure respiration.Objective: To determine the risk factors associated with failure in noninvasive mechanical ventilation (NIV) in a pediatric intensive care unit. Methods: Retrospective cohort from medical records of patients admitted to the Pediatric ICU of a Hospital in Caxias do Sul, between May 2017 and October 2019, who used NIV. Results: The incidence of NIV failure was 33%. Asthma patients, post-extubation use, continuous use, closure at night, final SIMV modality, ventilatory parameters, initial PEEP, and final FIO2 were also associated with failure. In vital signs, the initial SBP and the final RF were significant. After multivariate analysis, final SIMV modality, closing at night, final PIP, and final RF were associated with NIV failure. Conclusion: SIMV final ventilatory modality, as well as NIV closure at night, higher final PIP and higher final RF are risk factors for NIV failure.Introdução: Suporte ventilatório é usado para o tratamento de pacientes com insuficiência respiratória aguda (IRpA) ou crônica agudizada. Objetivo foi determinar os fatores de risco associados à falha na VNI em uma unidade de terapia intensiva pediátrica.Métodos: Coorte retrospectiva a partir de prontuários de pacientes admitidos na unidade de terapia intensiva (UTI) Pediátrica de um Hospital de Caxias do Sul, entremaio de 2017 e outubro de 2019, que utilizaram VNI.Resultados: Incidência de falha na VNI foi de 33%. Asma (RR = 1,36; IC95% = 1,08- 1,72), uso de VNI em pacientes pós-extubação (RR = 1,97; IC95% = 1,17-3,29), uso contínuo da VNI (RR = 2,44; IC95% = 1,18-5,05), encerramento à noite (RR = 2,52; IC95% = 1,53-4,14), modalidade final ventilação mandatória intermitente sincronizada (SIMV) (RR = 4,20; IC95% = 2,20-7,90), pressão expiratória positiva final (PEEP) no início da ventilação (6,8 ± 1,1; p < 0,01) e fração inspiratória de O2 (FIO2) final (53,10 ± 18,50; p < 0,01) foram associados à falha. Adicionalmente, pressão arterialsistólica (PAS) inicial (118,68 ± 18,68 mmHg; p = 0,02), frequência respiratória inicial (FR) (47,69 ± 14,76; p = 0,28) e final (47,54 ± 14,76; p < 0,01) foram associados a falha.Conclusão: Modalidade ventilatória final SIMV, demostra ser o melhor preditor de risco de falha, seguido do turno em que a VNI é finalizada, onde à noite existe maior risco de falha. Foram preditores de falha, porém com menor robustez, a pressão positiva inspiratória (PIP) final e a FR final.HCPA/FAMED/UFRGS2022-05-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed ArticleAvaliado por Paresapplication/pdfhttps://seer.ufrgs.br/index.php/hcpa/article/view/112032Clinical & Biomedical Research; Vol. 42 No. 1 (2022): Clinical and Biomedical ResearchClinical and Biomedical Research; v. 42 n. 1 (2022): Clinical and Biomedical Research2357-9730reponame:Clinical and Biomedical Researchinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSporhttps://seer.ufrgs.br/index.php/hcpa/article/view/112032/84835Copyright (c) 2022 Clinical and Biomedical Researchhttp://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessStumm, GlauciaPereira, VagnerWolf, Jonas MichelFurlin, ElisangelaTurcatto, JanaínaSaldanha, MarceloDani, CarolineForgiarini, Luiz2024-01-19T14:12:51Zoai:seer.ufrgs.br:article/112032Revistahttps://www.seer.ufrgs.br/index.php/hcpaPUBhttps://seer.ufrgs.br/index.php/hcpa/oai||cbr@hcpa.edu.br2357-97302357-9730opendoar:2024-01-19T14:12:51Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.none.fl_str_mv |
Incidence and risk factors associated with non-invasive ventilation failure in pediatric patients Incidência e fatores de risco associados à falha na ventilação não invasiva em pacientes pediátricos |
title |
Incidence and risk factors associated with non-invasive ventilation failure in pediatric patients |
spellingShingle |
Incidence and risk factors associated with non-invasive ventilation failure in pediatric patients Stumm, Glaucia Risk factors Noninvasive ventilation Pediatric Intensive Care Unit Respiratory failure Mechanical ventilation Positive-pressure respiration. |
title_short |
Incidence and risk factors associated with non-invasive ventilation failure in pediatric patients |
title_full |
Incidence and risk factors associated with non-invasive ventilation failure in pediatric patients |
title_fullStr |
Incidence and risk factors associated with non-invasive ventilation failure in pediatric patients |
title_full_unstemmed |
Incidence and risk factors associated with non-invasive ventilation failure in pediatric patients |
title_sort |
Incidence and risk factors associated with non-invasive ventilation failure in pediatric patients |
author |
Stumm, Glaucia |
author_facet |
Stumm, Glaucia Pereira, Vagner Wolf, Jonas Michel Furlin, Elisangela Turcatto, Janaína Saldanha, Marcelo Dani, Caroline Forgiarini, Luiz |
author_role |
author |
author2 |
Pereira, Vagner Wolf, Jonas Michel Furlin, Elisangela Turcatto, Janaína Saldanha, Marcelo Dani, Caroline Forgiarini, Luiz |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Stumm, Glaucia Pereira, Vagner Wolf, Jonas Michel Furlin, Elisangela Turcatto, Janaína Saldanha, Marcelo Dani, Caroline Forgiarini, Luiz |
dc.subject.por.fl_str_mv |
Risk factors Noninvasive ventilation Pediatric Intensive Care Unit Respiratory failure Mechanical ventilation Positive-pressure respiration. |
topic |
Risk factors Noninvasive ventilation Pediatric Intensive Care Unit Respiratory failure Mechanical ventilation Positive-pressure respiration. |
description |
Objective: To determine the risk factors associated with failure in noninvasive mechanical ventilation (NIV) in a pediatric intensive care unit. Methods: Retrospective cohort from medical records of patients admitted to the Pediatric ICU of a Hospital in Caxias do Sul, between May 2017 and October 2019, who used NIV. Results: The incidence of NIV failure was 33%. Asthma patients, post-extubation use, continuous use, closure at night, final SIMV modality, ventilatory parameters, initial PEEP, and final FIO2 were also associated with failure. In vital signs, the initial SBP and the final RF were significant. After multivariate analysis, final SIMV modality, closing at night, final PIP, and final RF were associated with NIV failure. Conclusion: SIMV final ventilatory modality, as well as NIV closure at night, higher final PIP and higher final RF are risk factors for NIV failure. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-05-25 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article Avaliado por Pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://seer.ufrgs.br/index.php/hcpa/article/view/112032 |
url |
https://seer.ufrgs.br/index.php/hcpa/article/view/112032 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://seer.ufrgs.br/index.php/hcpa/article/view/112032/84835 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2022 Clinical and Biomedical Research http://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2022 Clinical and Biomedical Research http://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
HCPA/FAMED/UFRGS |
publisher.none.fl_str_mv |
HCPA/FAMED/UFRGS |
dc.source.none.fl_str_mv |
Clinical & Biomedical Research; Vol. 42 No. 1 (2022): Clinical and Biomedical Research Clinical and Biomedical Research; v. 42 n. 1 (2022): Clinical and Biomedical Research 2357-9730 reponame:Clinical and Biomedical Research instname:Universidade Federal do Rio Grande do Sul (UFRGS) instacron:UFRGS |
instname_str |
Universidade Federal do Rio Grande do Sul (UFRGS) |
instacron_str |
UFRGS |
institution |
UFRGS |
reponame_str |
Clinical and Biomedical Research |
collection |
Clinical and Biomedical Research |
repository.name.fl_str_mv |
Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS) |
repository.mail.fl_str_mv |
||cbr@hcpa.edu.br |
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1799767056252403712 |