Diagnosis, risk factors and pathogenesis of preeclampsia

Detalhes bibliográficos
Autor(a) principal: Orcy, Rafael Bueno
Data de Publicação: 2008
Outros Autores: Pedrini, Renata, Piccinini, Pedro, Schroeder, Sabrina, Martins-Costa, Sérgio Hofmeister, Ramos, José Geraldo Lopes, Capp, Edison, Corleta, Helena von Eye
Tipo de documento: Artigo
Idioma: por
Título da fonte: Clinical and Biomedical Research
Texto Completo: https://seer.ufrgs.br/index.php/hcpa/article/view/1981
Resumo: Preeclampsia is an illness of the gestation that involves fetal growth restriction, prematurity and, in more severe cases, death of mother and fetus. It is characterized by maternal hypertension, significant proteinuria (? 0,3g/24 h), edema, vasoconstriction of maternal blood vessels and consequent increase in vascular resistance. Many studies discuss risk factors, pathogenesis and diagnostic criteria of preeclampsia; however, there are large variations in presentation and clinical course of this illness, which make interpretation of fre-quently conflicting results difficult. Diagnostic standardization and research of genetic and molecular bases can bring a better understand-ing of this pathology in a near future. In this paper, we present a review of the literature, stressing the relation between preeclampsia and insulin resistance.
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spelling Diagnosis, risk factors and pathogenesis of preeclampsiaDiagnóstico, fatores de risco e patogênese da pré-eclâmpsiapré-eclâmpsiadiagnósticofatores de riscofisiopatologiaresistência à insulinaPré-Eclâmpsiaresistência à insulinaPreeclampsia is an illness of the gestation that involves fetal growth restriction, prematurity and, in more severe cases, death of mother and fetus. It is characterized by maternal hypertension, significant proteinuria (? 0,3g/24 h), edema, vasoconstriction of maternal blood vessels and consequent increase in vascular resistance. Many studies discuss risk factors, pathogenesis and diagnostic criteria of preeclampsia; however, there are large variations in presentation and clinical course of this illness, which make interpretation of fre-quently conflicting results difficult. Diagnostic standardization and research of genetic and molecular bases can bring a better understand-ing of this pathology in a near future. In this paper, we present a review of the literature, stressing the relation between preeclampsia and insulin resistance.A pré-eclâmpsia é uma doença da gestação que pode determinar restrição no crescimento fetal, prematuridade e, em casos mais graves, morte da mãe e do feto. Caracteriza-se por hipertensão arterial materna, proteinúria significativa (? 0,3g/24h), edema, vaso-constrição do leito vascular materno e conseqüente aumento da resistência vascular. Muitos estudos discutem fatores de risco, patogê-nese e critérios para o diagnóstico da pré-eclampsia, porém as variações na forma de apresentação e de evolução clínica dessa doença dificultam o entendimento dos resultados obtidos, freqüentemente conflitantes. A padronização diagnóstica e as pesquisas de base genética e molecular podem trazer, em um futuro próximo, maior compreensão dessa patologia. Neste artigo apresentamos uma revisão da literatura, com destaque para a relação entre pré-eclâmpsia e resistência à insulina.HCPA/FAMED/UFRGS2008-01-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed ArticleAvaliados por Paresapplication/pdfhttps://seer.ufrgs.br/index.php/hcpa/article/view/1981Clinical & Biomedical Research; Vol. 27 No. 3 (2007): Revista HCPAClinical and Biomedical Research; v. 27 n. 3 (2007): Revista HCPA2357-9730reponame:Clinical and Biomedical Researchinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSporhttps://seer.ufrgs.br/index.php/hcpa/article/view/1981/1579Orcy, Rafael BuenoPedrini, RenataPiccinini, PedroSchroeder, SabrinaMartins-Costa, Sérgio HofmeisterRamos, José Geraldo LopesCapp, EdisonCorleta, Helena von Eyeinfo:eu-repo/semantics/openAccess2020-01-16T16:14:10Zoai:seer.ufrgs.br:article/1981Revistahttps://www.seer.ufrgs.br/index.php/hcpaPUBhttps://seer.ufrgs.br/index.php/hcpa/oai||cbr@hcpa.edu.br2357-97302357-9730opendoar:2020-01-16T16:14:10Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.none.fl_str_mv Diagnosis, risk factors and pathogenesis of preeclampsia
Diagnóstico, fatores de risco e patogênese da pré-eclâmpsia
title Diagnosis, risk factors and pathogenesis of preeclampsia
spellingShingle Diagnosis, risk factors and pathogenesis of preeclampsia
Orcy, Rafael Bueno
pré-eclâmpsia
diagnóstico
fatores de risco
fisiopatologia
resistência à insulina
Pré-Eclâmpsia
resistência à insulina
title_short Diagnosis, risk factors and pathogenesis of preeclampsia
title_full Diagnosis, risk factors and pathogenesis of preeclampsia
title_fullStr Diagnosis, risk factors and pathogenesis of preeclampsia
title_full_unstemmed Diagnosis, risk factors and pathogenesis of preeclampsia
title_sort Diagnosis, risk factors and pathogenesis of preeclampsia
author Orcy, Rafael Bueno
author_facet Orcy, Rafael Bueno
Pedrini, Renata
Piccinini, Pedro
Schroeder, Sabrina
Martins-Costa, Sérgio Hofmeister
Ramos, José Geraldo Lopes
Capp, Edison
Corleta, Helena von Eye
author_role author
author2 Pedrini, Renata
Piccinini, Pedro
Schroeder, Sabrina
Martins-Costa, Sérgio Hofmeister
Ramos, José Geraldo Lopes
Capp, Edison
Corleta, Helena von Eye
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Orcy, Rafael Bueno
Pedrini, Renata
Piccinini, Pedro
Schroeder, Sabrina
Martins-Costa, Sérgio Hofmeister
Ramos, José Geraldo Lopes
Capp, Edison
Corleta, Helena von Eye
dc.subject.por.fl_str_mv pré-eclâmpsia
diagnóstico
fatores de risco
fisiopatologia
resistência à insulina
Pré-Eclâmpsia
resistência à insulina
topic pré-eclâmpsia
diagnóstico
fatores de risco
fisiopatologia
resistência à insulina
Pré-Eclâmpsia
resistência à insulina
description Preeclampsia is an illness of the gestation that involves fetal growth restriction, prematurity and, in more severe cases, death of mother and fetus. It is characterized by maternal hypertension, significant proteinuria (? 0,3g/24 h), edema, vasoconstriction of maternal blood vessels and consequent increase in vascular resistance. Many studies discuss risk factors, pathogenesis and diagnostic criteria of preeclampsia; however, there are large variations in presentation and clinical course of this illness, which make interpretation of fre-quently conflicting results difficult. Diagnostic standardization and research of genetic and molecular bases can bring a better understand-ing of this pathology in a near future. In this paper, we present a review of the literature, stressing the relation between preeclampsia and insulin resistance.
publishDate 2008
dc.date.none.fl_str_mv 2008-01-02
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
Avaliados por Pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://seer.ufrgs.br/index.php/hcpa/article/view/1981
url https://seer.ufrgs.br/index.php/hcpa/article/view/1981
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://seer.ufrgs.br/index.php/hcpa/article/view/1981/1579
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv HCPA/FAMED/UFRGS
publisher.none.fl_str_mv HCPA/FAMED/UFRGS
dc.source.none.fl_str_mv Clinical & Biomedical Research; Vol. 27 No. 3 (2007): Revista HCPA
Clinical and Biomedical Research; v. 27 n. 3 (2007): Revista HCPA
2357-9730
reponame:Clinical and Biomedical Research
instname:Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
instname_str Universidade Federal do Rio Grande do Sul (UFRGS)
instacron_str UFRGS
institution UFRGS
reponame_str Clinical and Biomedical Research
collection Clinical and Biomedical Research
repository.name.fl_str_mv Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)
repository.mail.fl_str_mv ||cbr@hcpa.edu.br
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