Implementation of a New Experimental Animal Model - Zebrafish

Detalhes bibliográficos
Autor(a) principal: Schneider, Ana Cláudia Reis
Data de Publicação: 2009
Outros Autores: Maurer, Rafael Lucyk, Matte, Ursula, Porawski, Marilene, Schaefer, Pedro Guilherme, dos Santos, Jorge Luiz, da Silveira, Themis Reverbel
Tipo de documento: Artigo
Idioma: por
Título da fonte: Clinical and Biomedical Research
Texto Completo: https://seer.ufrgs.br/index.php/hcpa/article/view/7981
Resumo: Danio rerio (zebrafish, paulistinha) is a freshwater small fish that has been used as an animal model for studies of several human diseases. Its characteristics of being easily bred and reproduced and its laboratory housing methods are well established. It requires some basic care and the acquisition of specific low-cost equipment. Since this fish has already been considered a good human disease model, it may serve as a powerful preclinical platform for the study of molecular events, therapeutic strategies, and for evaluating the physiological mechanisms of some pathologies. The Laboratory of Experimental Hepatology and Gastroenterology (LEHG) of the Research Center of Hospital de Clínicas de Porto Alegre initiated studies with the zebrafish in 2008, presented here.
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spelling Implementation of a New Experimental Animal Model - ZebrafishImplementação de um Novo Modelo de Experimentação Animal - ZebrafishZebrafishDanio rerioModelo AnimalZebrafischdanio rerioDanio rerio (zebrafish, paulistinha) is a freshwater small fish that has been used as an animal model for studies of several human diseases. Its characteristics of being easily bred and reproduced and its laboratory housing methods are well established. It requires some basic care and the acquisition of specific low-cost equipment. Since this fish has already been considered a good human disease model, it may serve as a powerful preclinical platform for the study of molecular events, therapeutic strategies, and for evaluating the physiological mechanisms of some pathologies. The Laboratory of Experimental Hepatology and Gastroenterology (LEHG) of the Research Center of Hospital de Clínicas de Porto Alegre initiated studies with the zebrafish in 2008, presented here.O Danio rerio (zebrafish, paulistinha) é um pequeno peixe de água-doce, que vem sendo utilizado como modelo de animal para o estudo de numerosas doenças humanas. A sua facilidade de manutenção e reprodução e os métodos laboratoriais para sua criação já estão bem estabelecidos. Sua manutenção requer alguns cuidados básicos e a compra de equipamentos específicos, porém estes são de baixo custo. Este peixe é considerado um bom modelo para o estudo de doenças humanas, pode servir como uma relevante plataforma para estudo de eventos moleculares, estratégias terapêuticas e avaliação dos mecanismos fisiológicos de algumas patologias. O Laboratório Experimental de Hepatologia e Gastroenterologia (LEHG), do Centro de Pesquisas do Hospital de Clínicas de Porto Alegre, iniciou em 2008 estudos na área da Hepatologia com o Zebrafish, aqui apresentados.HCPA/FAMED/UFRGS2009-08-17info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed ArticleAvaliado por Paresapplication/pdfhttps://seer.ufrgs.br/index.php/hcpa/article/view/7981Clinical & Biomedical Research; Vol. 29 No. 2 (2009): Revista HCPAClinical and Biomedical Research; v. 29 n. 2 (2009): Revista HCPA2357-9730reponame:Clinical and Biomedical Researchinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSporhttps://seer.ufrgs.br/index.php/hcpa/article/view/7981/5572Schneider, Ana Cláudia ReisMaurer, Rafael LucykMatte, UrsulaPorawski, MarileneSchaefer, Pedro Guilhermedos Santos, Jorge Luizda Silveira, Themis Reverbelinfo:eu-repo/semantics/openAccess2020-01-16T16:20:25Zoai:seer.ufrgs.br:article/7981Revistahttps://www.seer.ufrgs.br/index.php/hcpaPUBhttps://seer.ufrgs.br/index.php/hcpa/oai||cbr@hcpa.edu.br2357-97302357-9730opendoar:2020-01-16T16:20:25Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.none.fl_str_mv Implementation of a New Experimental Animal Model - Zebrafish
Implementação de um Novo Modelo de Experimentação Animal - Zebrafish
title Implementation of a New Experimental Animal Model - Zebrafish
spellingShingle Implementation of a New Experimental Animal Model - Zebrafish
Schneider, Ana Cláudia Reis
Zebrafish
Danio rerio
Modelo Animal
Zebrafisch
danio rerio
title_short Implementation of a New Experimental Animal Model - Zebrafish
title_full Implementation of a New Experimental Animal Model - Zebrafish
title_fullStr Implementation of a New Experimental Animal Model - Zebrafish
title_full_unstemmed Implementation of a New Experimental Animal Model - Zebrafish
title_sort Implementation of a New Experimental Animal Model - Zebrafish
author Schneider, Ana Cláudia Reis
author_facet Schneider, Ana Cláudia Reis
Maurer, Rafael Lucyk
Matte, Ursula
Porawski, Marilene
Schaefer, Pedro Guilherme
dos Santos, Jorge Luiz
da Silveira, Themis Reverbel
author_role author
author2 Maurer, Rafael Lucyk
Matte, Ursula
Porawski, Marilene
Schaefer, Pedro Guilherme
dos Santos, Jorge Luiz
da Silveira, Themis Reverbel
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Schneider, Ana Cláudia Reis
Maurer, Rafael Lucyk
Matte, Ursula
Porawski, Marilene
Schaefer, Pedro Guilherme
dos Santos, Jorge Luiz
da Silveira, Themis Reverbel
dc.subject.por.fl_str_mv Zebrafish
Danio rerio
Modelo Animal
Zebrafisch
danio rerio
topic Zebrafish
Danio rerio
Modelo Animal
Zebrafisch
danio rerio
description Danio rerio (zebrafish, paulistinha) is a freshwater small fish that has been used as an animal model for studies of several human diseases. Its characteristics of being easily bred and reproduced and its laboratory housing methods are well established. It requires some basic care and the acquisition of specific low-cost equipment. Since this fish has already been considered a good human disease model, it may serve as a powerful preclinical platform for the study of molecular events, therapeutic strategies, and for evaluating the physiological mechanisms of some pathologies. The Laboratory of Experimental Hepatology and Gastroenterology (LEHG) of the Research Center of Hospital de Clínicas de Porto Alegre initiated studies with the zebrafish in 2008, presented here.
publishDate 2009
dc.date.none.fl_str_mv 2009-08-17
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
Avaliado por Pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://seer.ufrgs.br/index.php/hcpa/article/view/7981
url https://seer.ufrgs.br/index.php/hcpa/article/view/7981
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://seer.ufrgs.br/index.php/hcpa/article/view/7981/5572
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv HCPA/FAMED/UFRGS
publisher.none.fl_str_mv HCPA/FAMED/UFRGS
dc.source.none.fl_str_mv Clinical & Biomedical Research; Vol. 29 No. 2 (2009): Revista HCPA
Clinical and Biomedical Research; v. 29 n. 2 (2009): Revista HCPA
2357-9730
reponame:Clinical and Biomedical Research
instname:Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
instname_str Universidade Federal do Rio Grande do Sul (UFRGS)
instacron_str UFRGS
institution UFRGS
reponame_str Clinical and Biomedical Research
collection Clinical and Biomedical Research
repository.name.fl_str_mv Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)
repository.mail.fl_str_mv ||cbr@hcpa.edu.br
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