Relationship of antecedent stressful life events to childhood and family history of anxiety and the course of panic disorder

• Autor(a) principal: G. Manfro, Gisele
• Data de Publicação: 2022
• Outros Autores: W. Otto, Michael, T. McArdle, Eliza, J. Worthington III, John, F. Rosenbaum, Jerrold, H. Pollack, Mark
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Clinical and Biomedical Research
• Texto Completo: https://seer.ufrgs.br/index.php/hcpa/article/view/125053
• topic: Life event; panic disorder; childhood anxiety; course; Eventos vitais; transtorno do pânico; ansiedade na infância; curso

OBJECTIVES: The authors examined the incidence of significant life events during the year prior to the onset of panic disorder and its relationship to childhood and family history of anxiety difficulties, comorbidity, and the course of illness.MATERIALS AND METHODS: 223 panic patients were followed in a naturalistic study of panic disorder.RESULTS: Similar to previous reports, antecedent negative life events occurred in the majority (80%) of patients. Patients with a childhood history of anxiety and comorbid adulthood major depression were more likely to report an antecedent, stressful life event.CONCLUSIONS: Antecedent events were not linked with comorbid adulthood anxiety disorders or a family history of anxiety difficulties. Despite its associations with childhoodnxiety pathology and adulthood major depression, the presence of an identifiable antecedent at the onset of panic disorder was not associated with the subsequent severity or course of the disorder.