Adjuvant systemic therapy for breast cancer
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Clinical and Biomedical Research |
Texto Completo: | https://seer.ufrgs.br/index.php/hcpa/article/view/125892 |
Resumo: | Since the 1970s, substantial progress has been made in the understanding of the biology of breast cancer, on diagnostic approaches, and in determination of risk factors. This progress has been associated with advancements in the efficacy of treatments. Currently, many patients are receiving treatments that used to be reserved for cases with metastases. Clinical, multi-centered trials carried out by different authors have allowed for a continuous reevaluation of the basis of knowledge and recommendations of adjuvant therapy. Breast cancer, in this sense, is now understood as a systemic disease, which corroborates the use of systemic therapy in early breast cancer. |
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Clinical and Biomedical Research |
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Adjuvant systemic therapy for breast cancerTratamento sistêmico adjuvante em câncer de mamaQuimioterapiahormonioterapiaterapia sistêmicafatores prognósticosChemotherapyhormone therapysystemic therapyprognostic factorsSince the 1970s, substantial progress has been made in the understanding of the biology of breast cancer, on diagnostic approaches, and in determination of risk factors. This progress has been associated with advancements in the efficacy of treatments. Currently, many patients are receiving treatments that used to be reserved for cases with metastases. Clinical, multi-centered trials carried out by different authors have allowed for a continuous reevaluation of the basis of knowledge and recommendations of adjuvant therapy. Breast cancer, in this sense, is now understood as a systemic disease, which corroborates the use of systemic therapy in early breast cancer.Um significativo progresso no conhecimento e compreensão da biologia do câncer de mama, dos métodos diagnósticos e da determinação dos fatores de risco ocorreu desde os anos 70, acompanhado de avanços na eficácia dos tratamentos. Hoje, muitas pacientes recebem tratamentos anteriormente reservados para casos metastáticos. Os ensaios clínicos multicêntricos desenvolvidos por diferentes grupos permitem uma contínua reavaliação das bases de conhecimento e indicações de tratamento adjuvante. O câncer de mama deixou de ser considerado loco-regional e é reconhecido como sistêmico desde o seu início, o que sustenta o uso de terapia sistêmica em casos iniciais.HCPA/FAMED/UFRGS2022-07-18info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed Article"A Convite dos Editoresapplication/pdfhttps://seer.ufrgs.br/index.php/hcpa/article/view/125892Clinical & Biomedical Research; Vol. 21 No. 2 (2001): Revista HCPAClinical and Biomedical Research; v. 21 n. 2 (2001): Revista HCPA2357-9730reponame:Clinical and Biomedical Researchinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSporhttps://seer.ufrgs.br/index.php/hcpa/article/view/125892/85524http://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessCavalheiro, José Antônio H. Menke, Carlos V. Biazús, Jorge L. Xavier, Nilton G. Rabin, Eliane Cericatto, Rodrigo C. Bittelbrunn, Ana 2022-07-18T19:41:10Zoai:seer.ufrgs.br:article/125892Revistahttps://www.seer.ufrgs.br/index.php/hcpaPUBhttps://seer.ufrgs.br/index.php/hcpa/oai||cbr@hcpa.edu.br2357-97302357-9730opendoar:2022-07-18T19:41:10Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.none.fl_str_mv |
Adjuvant systemic therapy for breast cancer Tratamento sistêmico adjuvante em câncer de mama |
title |
Adjuvant systemic therapy for breast cancer |
spellingShingle |
Adjuvant systemic therapy for breast cancer Cavalheiro, José Antônio Quimioterapia hormonioterapia terapia sistêmica fatores prognósticos Chemotherapy hormone therapy systemic therapy prognostic factors |
title_short |
Adjuvant systemic therapy for breast cancer |
title_full |
Adjuvant systemic therapy for breast cancer |
title_fullStr |
Adjuvant systemic therapy for breast cancer |
title_full_unstemmed |
Adjuvant systemic therapy for breast cancer |
title_sort |
Adjuvant systemic therapy for breast cancer |
author |
Cavalheiro, José Antônio |
author_facet |
Cavalheiro, José Antônio H. Menke, Carlos V. Biazús, Jorge L. Xavier, Nilton G. Rabin, Eliane Cericatto, Rodrigo C. Bittelbrunn, Ana |
author_role |
author |
author2 |
H. Menke, Carlos V. Biazús, Jorge L. Xavier, Nilton G. Rabin, Eliane Cericatto, Rodrigo C. Bittelbrunn, Ana |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Cavalheiro, José Antônio H. Menke, Carlos V. Biazús, Jorge L. Xavier, Nilton G. Rabin, Eliane Cericatto, Rodrigo C. Bittelbrunn, Ana |
dc.subject.por.fl_str_mv |
Quimioterapia hormonioterapia terapia sistêmica fatores prognósticos Chemotherapy hormone therapy systemic therapy prognostic factors |
topic |
Quimioterapia hormonioterapia terapia sistêmica fatores prognósticos Chemotherapy hormone therapy systemic therapy prognostic factors |
description |
Since the 1970s, substantial progress has been made in the understanding of the biology of breast cancer, on diagnostic approaches, and in determination of risk factors. This progress has been associated with advancements in the efficacy of treatments. Currently, many patients are receiving treatments that used to be reserved for cases with metastases. Clinical, multi-centered trials carried out by different authors have allowed for a continuous reevaluation of the basis of knowledge and recommendations of adjuvant therapy. Breast cancer, in this sense, is now understood as a systemic disease, which corroborates the use of systemic therapy in early breast cancer. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-07-18 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article" A Convite dos Editores |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://seer.ufrgs.br/index.php/hcpa/article/view/125892 |
url |
https://seer.ufrgs.br/index.php/hcpa/article/view/125892 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://seer.ufrgs.br/index.php/hcpa/article/view/125892/85524 |
dc.rights.driver.fl_str_mv |
http://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
http://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
HCPA/FAMED/UFRGS |
publisher.none.fl_str_mv |
HCPA/FAMED/UFRGS |
dc.source.none.fl_str_mv |
Clinical & Biomedical Research; Vol. 21 No. 2 (2001): Revista HCPA Clinical and Biomedical Research; v. 21 n. 2 (2001): Revista HCPA 2357-9730 reponame:Clinical and Biomedical Research instname:Universidade Federal do Rio Grande do Sul (UFRGS) instacron:UFRGS |
instname_str |
Universidade Federal do Rio Grande do Sul (UFRGS) |
instacron_str |
UFRGS |
institution |
UFRGS |
reponame_str |
Clinical and Biomedical Research |
collection |
Clinical and Biomedical Research |
repository.name.fl_str_mv |
Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS) |
repository.mail.fl_str_mv |
||cbr@hcpa.edu.br |
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1799767057450926080 |