Proteinuria: clinical and laboratory approach

Detalhes bibliográficos
Autor(a) principal: V. Morales, José
Data de Publicação: 2022
Outros Autores: Garcez, Joana, Weber, Raimar, L. Klamt, Charles, Barros, Elvino
Tipo de documento: Artigo
Idioma: por
Título da fonte: Clinical and Biomedical Research
Texto Completo: https://seer.ufrgs.br/index.php/hcpa/article/view/125388
Resumo: Proteinuria is a strong indicator of renal disease and it is present in many syndromes. Our objective is to review the pathophysiological mechanisms that lead to proteinuria, as well as the available methods for its detection and quantitation, including the dipstick, 24-hour proteinuria, and the urinary protein-creatinine ratio. We gave special attention to clinical evaluation of proteinuric patients, including the available exams and the situations in which they are indicated. An algorithm for the investigation of patients with proteinuria is presented. We also emphasized the importance of persistent proteinuria in its relation with the progression of renal diseases.
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spelling Proteinuria: clinical and laboratory approachProteinúria: avaliação clínica e laboratorialProteinúriaglomerulonefritesíndrome nefróticaProteinuriaglomerulonephritisnephrotic syndromeProteinuria is a strong indicator of renal disease and it is present in many syndromes. Our objective is to review the pathophysiological mechanisms that lead to proteinuria, as well as the available methods for its detection and quantitation, including the dipstick, 24-hour proteinuria, and the urinary protein-creatinine ratio. We gave special attention to clinical evaluation of proteinuric patients, including the available exams and the situations in which they are indicated. An algorithm for the investigation of patients with proteinuria is presented. We also emphasized the importance of persistent proteinuria in its relation with the progression of renal diseases.Proteinúria é um forte indicador de doença renal, e está presente em diversas síndromes. No presente artigo, os mecanismos fisiopatológicos que levam à proteinúria foram revisados, assim como os métodos disponíveis para sua detecção e quantificação, incluindo a fita reagente, proteinúria de 24 horas e o índice proteína/creatinina na urina. Atenção especial é dada à avaliação clínica dos pacientes com proteinúria, abordando os exames disponíveis e as situações em que são indicados. Um fluxograma para a investigação de pacientes com proteinúria é apresentado. Também ressaltamos a importância da proteinúria persistente na sua relação com a progressão de doenças renaisHCPA/FAMED/UFRGS2022-06-23info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed Article"A Convite dos Editoresapplication/pdfhttps://seer.ufrgs.br/index.php/hcpa/article/view/125388Clinical & Biomedical Research; Vol. 20 No. 3 (2000): Revista HCPAClinical and Biomedical Research; v. 20 n. 3 (2000): Revista HCPA2357-9730reponame:Clinical and Biomedical Researchinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSporhttps://seer.ufrgs.br/index.php/hcpa/article/view/125388/85239http://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessV. Morales, JoséGarcez, Joana Weber, Raimar L. Klamt, Charles Barros, Elvino 2022-09-16T16:33:15Zoai:seer.ufrgs.br:article/125388Revistahttps://www.seer.ufrgs.br/index.php/hcpaPUBhttps://seer.ufrgs.br/index.php/hcpa/oai||cbr@hcpa.edu.br2357-97302357-9730opendoar:2022-09-16T16:33:15Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.none.fl_str_mv Proteinuria: clinical and laboratory approach
Proteinúria: avaliação clínica e laboratorial
title Proteinuria: clinical and laboratory approach
spellingShingle Proteinuria: clinical and laboratory approach
V. Morales, José
Proteinúria
glomerulonefrite
síndrome nefrótica
Proteinuria
glomerulonephritis
nephrotic syndrome
title_short Proteinuria: clinical and laboratory approach
title_full Proteinuria: clinical and laboratory approach
title_fullStr Proteinuria: clinical and laboratory approach
title_full_unstemmed Proteinuria: clinical and laboratory approach
title_sort Proteinuria: clinical and laboratory approach
author V. Morales, José
author_facet V. Morales, José
Garcez, Joana
Weber, Raimar
L. Klamt, Charles
Barros, Elvino
author_role author
author2 Garcez, Joana
Weber, Raimar
L. Klamt, Charles
Barros, Elvino
author2_role author
author
author
author
dc.contributor.author.fl_str_mv V. Morales, José
Garcez, Joana
Weber, Raimar
L. Klamt, Charles
Barros, Elvino
dc.subject.por.fl_str_mv Proteinúria
glomerulonefrite
síndrome nefrótica
Proteinuria
glomerulonephritis
nephrotic syndrome
topic Proteinúria
glomerulonefrite
síndrome nefrótica
Proteinuria
glomerulonephritis
nephrotic syndrome
description Proteinuria is a strong indicator of renal disease and it is present in many syndromes. Our objective is to review the pathophysiological mechanisms that lead to proteinuria, as well as the available methods for its detection and quantitation, including the dipstick, 24-hour proteinuria, and the urinary protein-creatinine ratio. We gave special attention to clinical evaluation of proteinuric patients, including the available exams and the situations in which they are indicated. An algorithm for the investigation of patients with proteinuria is presented. We also emphasized the importance of persistent proteinuria in its relation with the progression of renal diseases.
publishDate 2022
dc.date.none.fl_str_mv 2022-06-23
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article"
A Convite dos Editores
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://seer.ufrgs.br/index.php/hcpa/article/view/125388
url https://seer.ufrgs.br/index.php/hcpa/article/view/125388
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://seer.ufrgs.br/index.php/hcpa/article/view/125388/85239
dc.rights.driver.fl_str_mv http://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv HCPA/FAMED/UFRGS
publisher.none.fl_str_mv HCPA/FAMED/UFRGS
dc.source.none.fl_str_mv Clinical & Biomedical Research; Vol. 20 No. 3 (2000): Revista HCPA
Clinical and Biomedical Research; v. 20 n. 3 (2000): Revista HCPA
2357-9730
reponame:Clinical and Biomedical Research
instname:Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
instname_str Universidade Federal do Rio Grande do Sul (UFRGS)
instacron_str UFRGS
institution UFRGS
reponame_str Clinical and Biomedical Research
collection Clinical and Biomedical Research
repository.name.fl_str_mv Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)
repository.mail.fl_str_mv ||cbr@hcpa.edu.br
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