Pandemic Influenza A (N1H1): what to learn from it?

Detalhes bibliográficos
Autor(a) principal: Neumann, Cristina Rolim
Data de Publicação: 2009
Outros Autores: Azambuja, Maria Inez Reinert, Oliveira, Francisco Arsego de, Falk, João Werner
Tipo de documento: Artigo
Idioma: por
Título da fonte: Clinical and Biomedical Research
Texto Completo: https://seer.ufrgs.br/index.php/hcpa/article/view/9926
Resumo: Influenza pandemics are natural events that occur periodically. The pandemic’s current agent, Influenza virus A (H1N1) was first identified in Mexico in April 2009, spread rapidly and has caused deaths mainly among young adults. The objective of this manuscript is to present the biological aspects involved in the outbreak of this pandemic, as well as population-control strategies for pandemic influenza. In addition to the population mitigation measures, whose efficacy has been described by theoretical models, today we also have drugs with efficacy valued in some patient groups. These drugs reduce moderately the duration and severity of symptoms, as long as they are started early. This pandemic, with a large number of cases, but caused by a virus of low lethality, could be managed preferably in Units of Primary Health Care, that would treat the wild cases and forward the severe ones to the hospitals. However, what occurred in numerous cities was the burden on emergency care with triage situations, forcing managers to improvise field hospitals, tents and containers to house the extra work in services that were already at the limit of physical infrastructure and human resources. Pandemic Influenza exposed the fragility of our network of primary care and lack of ICU beds.
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spelling Pandemic Influenza A (N1H1): what to learn from it?Pandemia de Influenza A (N1H1): O Que Aprender com Ela?Influenza AN1H1PandemiaGripe AGripeEpidemiologiaInfluenza AEpidemiologyInfluenza pandemics are natural events that occur periodically. The pandemic’s current agent, Influenza virus A (H1N1) was first identified in Mexico in April 2009, spread rapidly and has caused deaths mainly among young adults. The objective of this manuscript is to present the biological aspects involved in the outbreak of this pandemic, as well as population-control strategies for pandemic influenza. In addition to the population mitigation measures, whose efficacy has been described by theoretical models, today we also have drugs with efficacy valued in some patient groups. These drugs reduce moderately the duration and severity of symptoms, as long as they are started early. This pandemic, with a large number of cases, but caused by a virus of low lethality, could be managed preferably in Units of Primary Health Care, that would treat the wild cases and forward the severe ones to the hospitals. However, what occurred in numerous cities was the burden on emergency care with triage situations, forcing managers to improvise field hospitals, tents and containers to house the extra work in services that were already at the limit of physical infrastructure and human resources. Pandemic Influenza exposed the fragility of our network of primary care and lack of ICU beds.Pandemias de gripe são eventos naturais que ocorrem periodicamente. O agente da pandemia atual, o vírus Influenza A (H1N1), foi identificado primeiramente no México em abril de 2009, disseminou-se rapidamente e tem causado óbitos principalmente entre adultos jovens. O objetivo deste manuscrito é apresentar os aspectos biológicos envolvidos na eclosão desta pandemia, bem como as estratégias de contenção populacional da pandemia de Influenza. Além das medidas populacionais, cuja eficácia tem sido descrita através de modelos teóricos, atualmente também dispomos de medicamentos com eficácia avaliada em alguns grupos de pacientes. Estes medicamentos reduzem moderadamente o tempo de duração e a gravidade dos sintomas, desde que iniciados precocemente. Esta pandemia, com um grande número de casos, mas causada por um vírus de baixa letalidade, poderia ser manejada preferentemente em Unidades de Atenção Primária à Saúde, que tratariam os casos leves e encaminhariam os graves aos hospitais. Contudo, o que ocorreu em inúmeras cidades foi a sobrecarga das emergências com situações de triagem, forçando os gestores a improvisar hospitais de campanha, containeres e tendas para abrigar o trabalho extra em serviços que já operavam no limite de estrutura física e de recursos humanos. A pandemia de Influenza expôs a fragilidade da nossa rede de atenção básica e a falta de leitos de UTI.HCPA/FAMED/UFRGS2009-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed Article"A Convite dos Editoresapplication/pdfhttps://seer.ufrgs.br/index.php/hcpa/article/view/9926Clinical & Biomedical Research; Vol. 29 No. 2 (2009): Revista HCPAClinical and Biomedical Research; v. 29 n. 2 (2009): Revista HCPA2357-9730reponame:Clinical and Biomedical Researchinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSporhttps://seer.ufrgs.br/index.php/hcpa/article/view/9926/5790Neumann, Cristina RolimAzambuja, Maria Inez ReinertOliveira, Francisco Arsego deFalk, João Wernerinfo:eu-repo/semantics/openAccess2020-01-16T16:20:25Zoai:seer.ufrgs.br:article/9926Revistahttps://www.seer.ufrgs.br/index.php/hcpaPUBhttps://seer.ufrgs.br/index.php/hcpa/oai||cbr@hcpa.edu.br2357-97302357-9730opendoar:2020-01-16T16:20:25Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.none.fl_str_mv Pandemic Influenza A (N1H1): what to learn from it?
Pandemia de Influenza A (N1H1): O Que Aprender com Ela?
title Pandemic Influenza A (N1H1): what to learn from it?
spellingShingle Pandemic Influenza A (N1H1): what to learn from it?
Neumann, Cristina Rolim
Influenza A
N1H1
Pandemia
Gripe A
Gripe
Epidemiologia
Influenza A
Epidemiology
title_short Pandemic Influenza A (N1H1): what to learn from it?
title_full Pandemic Influenza A (N1H1): what to learn from it?
title_fullStr Pandemic Influenza A (N1H1): what to learn from it?
title_full_unstemmed Pandemic Influenza A (N1H1): what to learn from it?
title_sort Pandemic Influenza A (N1H1): what to learn from it?
author Neumann, Cristina Rolim
author_facet Neumann, Cristina Rolim
Azambuja, Maria Inez Reinert
Oliveira, Francisco Arsego de
Falk, João Werner
author_role author
author2 Azambuja, Maria Inez Reinert
Oliveira, Francisco Arsego de
Falk, João Werner
author2_role author
author
author
dc.contributor.author.fl_str_mv Neumann, Cristina Rolim
Azambuja, Maria Inez Reinert
Oliveira, Francisco Arsego de
Falk, João Werner
dc.subject.por.fl_str_mv Influenza A
N1H1
Pandemia
Gripe A
Gripe
Epidemiologia
Influenza A
Epidemiology
topic Influenza A
N1H1
Pandemia
Gripe A
Gripe
Epidemiologia
Influenza A
Epidemiology
description Influenza pandemics are natural events that occur periodically. The pandemic’s current agent, Influenza virus A (H1N1) was first identified in Mexico in April 2009, spread rapidly and has caused deaths mainly among young adults. The objective of this manuscript is to present the biological aspects involved in the outbreak of this pandemic, as well as population-control strategies for pandemic influenza. In addition to the population mitigation measures, whose efficacy has been described by theoretical models, today we also have drugs with efficacy valued in some patient groups. These drugs reduce moderately the duration and severity of symptoms, as long as they are started early. This pandemic, with a large number of cases, but caused by a virus of low lethality, could be managed preferably in Units of Primary Health Care, that would treat the wild cases and forward the severe ones to the hospitals. However, what occurred in numerous cities was the burden on emergency care with triage situations, forcing managers to improvise field hospitals, tents and containers to house the extra work in services that were already at the limit of physical infrastructure and human resources. Pandemic Influenza exposed the fragility of our network of primary care and lack of ICU beds.
publishDate 2009
dc.date.none.fl_str_mv 2009-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article"
A Convite dos Editores
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://seer.ufrgs.br/index.php/hcpa/article/view/9926
url https://seer.ufrgs.br/index.php/hcpa/article/view/9926
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://seer.ufrgs.br/index.php/hcpa/article/view/9926/5790
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv HCPA/FAMED/UFRGS
publisher.none.fl_str_mv HCPA/FAMED/UFRGS
dc.source.none.fl_str_mv Clinical & Biomedical Research; Vol. 29 No. 2 (2009): Revista HCPA
Clinical and Biomedical Research; v. 29 n. 2 (2009): Revista HCPA
2357-9730
reponame:Clinical and Biomedical Research
instname:Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
instname_str Universidade Federal do Rio Grande do Sul (UFRGS)
instacron_str UFRGS
institution UFRGS
reponame_str Clinical and Biomedical Research
collection Clinical and Biomedical Research
repository.name.fl_str_mv Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)
repository.mail.fl_str_mv ||cbr@hcpa.edu.br
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