Continuous venovenous hemodialysis in the treatment of acute lithium intoxication

Detalhes bibliográficos
Autor(a) principal: Klafke, Adriana
Data de Publicação: 2022
Outros Autores: M. Dorigoni, Sílvia, G. Barros, Elvino José
Tipo de documento: Artigo
Idioma: por
Título da fonte: Clinical and Biomedical Research
Texto Completo: https://seer.ufrgs.br/index.php/hcpa/article/view/125423
Resumo: Our objective is to report a case of acute lithium carbonate self-poisoning. The patient presented with severe neuro logical and cardiovascular manifestations of lithium toxicity and with high serum lithium levels (8.0 mEq/l). Six hours after the first hemodialysis session, the patient evolved to a status of generalized tonic-clonic seizures (serum lithium 4.7 mEq/l). Seizures persisted for 4 days and with serum lithium varying from 2.5- 4.7 mEq/l until continuous venovenous hemodialysis was initiated. After 18 hours, serum lithium levels returned to normal (0.9 mmol/l) and the patient regained normal neurological function. We concluded that continuous venovenous hemodialysis can be a successful alternative for the treatment of acute lithium intoxication.
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spelling Continuous venovenous hemodialysis in the treatment of acute lithium intoxicationHemodiálise veno-venosa lenta contínua no tratamento da intoxicação aguda por lítioIntoxicação agudalítiohemodiálise veno-venosa lenta contínuaAcute lithium intoxicationlithiumcontinuous venovenous hemodialysisOur objective is to report a case of acute lithium carbonate self-poisoning. The patient presented with severe neuro logical and cardiovascular manifestations of lithium toxicity and with high serum lithium levels (8.0 mEq/l). Six hours after the first hemodialysis session, the patient evolved to a status of generalized tonic-clonic seizures (serum lithium 4.7 mEq/l). Seizures persisted for 4 days and with serum lithium varying from 2.5- 4.7 mEq/l until continuous venovenous hemodialysis was initiated. After 18 hours, serum lithium levels returned to normal (0.9 mmol/l) and the patient regained normal neurological function. We concluded that continuous venovenous hemodialysis can be a successful alternative for the treatment of acute lithium intoxication.Descrevemos um caso de intoxicação aguda por carbonato de lítio devido à tentativa de suicídio. O paciente apresentou-se com quadro neurológico e cardiovascular grave com lítio sérico de 8,0 mEq/L. Evoluiu para quadro convulsivo de difícil controle medicamentoso 6 horas após o término da primeira sessão de hemodiálise (lítio sérico 4,7 mEq/L). As convulsões tônico-clônicas generalizadas permaneceram durante 4 dias com os níveis séricos do lítio variando de 2,5 - 4,7 mEq/L até a instituição da hemodiálise veno-venosa lenta contínua durante 18 horas. Ocorreu então controle do quadro convulsivo e melhora dos níveis séricos do lítio (0,9 mEq/L).HCPA/FAMED/UFRGS2022-06-23info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed ArticleAvaliado por paresapplication/pdfhttps://seer.ufrgs.br/index.php/hcpa/article/view/125423Clinical & Biomedical Research; Vol. 20 No. 3 (2000): Revista HCPAClinical and Biomedical Research; v. 20 n. 3 (2000): Revista HCPA2357-9730reponame:Clinical and Biomedical Researchinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSporhttps://seer.ufrgs.br/index.php/hcpa/article/view/125423/85264http://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessKlafke, Adriana M. Dorigoni, Sílvia G. Barros, Elvino José 2022-09-16T16:33:15Zoai:seer.ufrgs.br:article/125423Revistahttps://www.seer.ufrgs.br/index.php/hcpaPUBhttps://seer.ufrgs.br/index.php/hcpa/oai||cbr@hcpa.edu.br2357-97302357-9730opendoar:2022-09-16T16:33:15Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.none.fl_str_mv Continuous venovenous hemodialysis in the treatment of acute lithium intoxication
Hemodiálise veno-venosa lenta contínua no tratamento da intoxicação aguda por lítio
title Continuous venovenous hemodialysis in the treatment of acute lithium intoxication
spellingShingle Continuous venovenous hemodialysis in the treatment of acute lithium intoxication
Klafke, Adriana
Intoxicação aguda
lítio
hemodiálise veno-venosa lenta contínua
Acute lithium intoxication
lithium
continuous venovenous hemodialysis
title_short Continuous venovenous hemodialysis in the treatment of acute lithium intoxication
title_full Continuous venovenous hemodialysis in the treatment of acute lithium intoxication
title_fullStr Continuous venovenous hemodialysis in the treatment of acute lithium intoxication
title_full_unstemmed Continuous venovenous hemodialysis in the treatment of acute lithium intoxication
title_sort Continuous venovenous hemodialysis in the treatment of acute lithium intoxication
author Klafke, Adriana
author_facet Klafke, Adriana
M. Dorigoni, Sílvia
G. Barros, Elvino José
author_role author
author2 M. Dorigoni, Sílvia
G. Barros, Elvino José
author2_role author
author
dc.contributor.author.fl_str_mv Klafke, Adriana
M. Dorigoni, Sílvia
G. Barros, Elvino José
dc.subject.por.fl_str_mv Intoxicação aguda
lítio
hemodiálise veno-venosa lenta contínua
Acute lithium intoxication
lithium
continuous venovenous hemodialysis
topic Intoxicação aguda
lítio
hemodiálise veno-venosa lenta contínua
Acute lithium intoxication
lithium
continuous venovenous hemodialysis
description Our objective is to report a case of acute lithium carbonate self-poisoning. The patient presented with severe neuro logical and cardiovascular manifestations of lithium toxicity and with high serum lithium levels (8.0 mEq/l). Six hours after the first hemodialysis session, the patient evolved to a status of generalized tonic-clonic seizures (serum lithium 4.7 mEq/l). Seizures persisted for 4 days and with serum lithium varying from 2.5- 4.7 mEq/l until continuous venovenous hemodialysis was initiated. After 18 hours, serum lithium levels returned to normal (0.9 mmol/l) and the patient regained normal neurological function. We concluded that continuous venovenous hemodialysis can be a successful alternative for the treatment of acute lithium intoxication.
publishDate 2022
dc.date.none.fl_str_mv 2022-06-23
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
Avaliado por pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://seer.ufrgs.br/index.php/hcpa/article/view/125423
url https://seer.ufrgs.br/index.php/hcpa/article/view/125423
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://seer.ufrgs.br/index.php/hcpa/article/view/125423/85264
dc.rights.driver.fl_str_mv http://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv HCPA/FAMED/UFRGS
publisher.none.fl_str_mv HCPA/FAMED/UFRGS
dc.source.none.fl_str_mv Clinical & Biomedical Research; Vol. 20 No. 3 (2000): Revista HCPA
Clinical and Biomedical Research; v. 20 n. 3 (2000): Revista HCPA
2357-9730
reponame:Clinical and Biomedical Research
instname:Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
instname_str Universidade Federal do Rio Grande do Sul (UFRGS)
instacron_str UFRGS
institution UFRGS
reponame_str Clinical and Biomedical Research
collection Clinical and Biomedical Research
repository.name.fl_str_mv Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)
repository.mail.fl_str_mv ||cbr@hcpa.edu.br
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