Influence of monoterpenes in biological activities of Nectandra megapotamica (Spreng.) mez essential oils
Autor(a) principal: | |
---|---|
Data de Publicação: | 2019 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/195870 |
Resumo: | Investigating the influence of seasonal variations on biological activities is important for pharmacological studies and metabolic engineering. Therefore, this study was conducted to determine the variation of the chemical composition of essential oils obtained from Nectandra megapotamica leaves, collected at different stages of plant development, as well as its influence on the biological activities. A total of 38 compounds were identified that accounted for 97–99.2% of the chemical composition of the oils. Major differences were observed in the monoterpenic fraction, representing 5.1% of the compounds identified in the productive rest phase to 37.1% in the blooming phase. Bicyclogermacrene and germacrene D were the predominant compounds identified in the oil of all collections. Furthermore, limonene, β-pinene, and spathulenol were identified predominantly in the samples of blooming and fruiting phases. The oils exhibited significant antichemotactic activity and different effects in scavenging the radical 2,2-diphenyl-1-picrylhydrazyl. Variations were also observed in the antifungal activity, with the minimum inhibitory concentrations ranging from 125 to 500 μg/mL. These results demonstrate the influence of monoterpenes, primarily limonene, α-pinene, and β-pinene, on the bioactivities of the oil. Studies investigating the variations in the chemical composition of essential oil may offer a strategy to produce a compound or a group of compounds of interest to industries with a specific pharmacological focus. |
id |
UFRGS-2_0946a9c5e3c22ea8a84927e3f4ac7629 |
---|---|
oai_identifier_str |
oai:www.lume.ufrgs.br:10183/195870 |
network_acronym_str |
UFRGS-2 |
network_name_str |
Repositório Institucional da UFRGS |
repository_id_str |
|
spelling |
Danielli, Letícia JacobiSouza, Tiago Juliano Tasso deMaciel, Ana JuliaFerrão, Marco FlôresFuentefria, Alexandre MeneghelloApel, Miriam Anders2019-06-18T02:34:39Z20192218-273Xhttp://hdl.handle.net/10183/195870001094577Investigating the influence of seasonal variations on biological activities is important for pharmacological studies and metabolic engineering. Therefore, this study was conducted to determine the variation of the chemical composition of essential oils obtained from Nectandra megapotamica leaves, collected at different stages of plant development, as well as its influence on the biological activities. A total of 38 compounds were identified that accounted for 97–99.2% of the chemical composition of the oils. Major differences were observed in the monoterpenic fraction, representing 5.1% of the compounds identified in the productive rest phase to 37.1% in the blooming phase. Bicyclogermacrene and germacrene D were the predominant compounds identified in the oil of all collections. Furthermore, limonene, β-pinene, and spathulenol were identified predominantly in the samples of blooming and fruiting phases. The oils exhibited significant antichemotactic activity and different effects in scavenging the radical 2,2-diphenyl-1-picrylhydrazyl. Variations were also observed in the antifungal activity, with the minimum inhibitory concentrations ranging from 125 to 500 μg/mL. These results demonstrate the influence of monoterpenes, primarily limonene, α-pinene, and β-pinene, on the bioactivities of the oil. Studies investigating the variations in the chemical composition of essential oil may offer a strategy to produce a compound or a group of compounds of interest to industries with a specific pharmacological focus.application/pdfengBiomolecules. Basel. Vol. 9, no. 3 (Mar. 2019), p. 1-12Óleo essencialMonoterpenosNectandra megapotamicaBiological activitiesEssential oilMonoterpenesNectandra megapotamicaPrincipal component analysisSeasonal variationInfluence of monoterpenes in biological activities of Nectandra megapotamica (Spreng.) mez essential oilsEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001094577.pdf.txt001094577.pdf.txtExtracted Texttext/plain48539http://www.lume.ufrgs.br/bitstream/10183/195870/2/001094577.pdf.txt952448dc2553aa58191417149a667779MD52ORIGINAL001094577.pdfTexto completo (inglês)application/pdf907920http://www.lume.ufrgs.br/bitstream/10183/195870/1/001094577.pdffb0ca001028ed9b7aead7a44c7f9ef1bMD5110183/1958702023-08-09 03:47:21.04461oai:www.lume.ufrgs.br:10183/195870Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2023-08-09T06:47:21Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Influence of monoterpenes in biological activities of Nectandra megapotamica (Spreng.) mez essential oils |
title |
Influence of monoterpenes in biological activities of Nectandra megapotamica (Spreng.) mez essential oils |
spellingShingle |
Influence of monoterpenes in biological activities of Nectandra megapotamica (Spreng.) mez essential oils Danielli, Letícia Jacobi Óleo essencial Monoterpenos Nectandra megapotamica Biological activities Essential oil Monoterpenes Nectandra megapotamica Principal component analysis Seasonal variation |
title_short |
Influence of monoterpenes in biological activities of Nectandra megapotamica (Spreng.) mez essential oils |
title_full |
Influence of monoterpenes in biological activities of Nectandra megapotamica (Spreng.) mez essential oils |
title_fullStr |
Influence of monoterpenes in biological activities of Nectandra megapotamica (Spreng.) mez essential oils |
title_full_unstemmed |
Influence of monoterpenes in biological activities of Nectandra megapotamica (Spreng.) mez essential oils |
title_sort |
Influence of monoterpenes in biological activities of Nectandra megapotamica (Spreng.) mez essential oils |
author |
Danielli, Letícia Jacobi |
author_facet |
Danielli, Letícia Jacobi Souza, Tiago Juliano Tasso de Maciel, Ana Julia Ferrão, Marco Flôres Fuentefria, Alexandre Meneghello Apel, Miriam Anders |
author_role |
author |
author2 |
Souza, Tiago Juliano Tasso de Maciel, Ana Julia Ferrão, Marco Flôres Fuentefria, Alexandre Meneghello Apel, Miriam Anders |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Danielli, Letícia Jacobi Souza, Tiago Juliano Tasso de Maciel, Ana Julia Ferrão, Marco Flôres Fuentefria, Alexandre Meneghello Apel, Miriam Anders |
dc.subject.por.fl_str_mv |
Óleo essencial Monoterpenos Nectandra megapotamica |
topic |
Óleo essencial Monoterpenos Nectandra megapotamica Biological activities Essential oil Monoterpenes Nectandra megapotamica Principal component analysis Seasonal variation |
dc.subject.eng.fl_str_mv |
Biological activities Essential oil Monoterpenes Nectandra megapotamica Principal component analysis Seasonal variation |
description |
Investigating the influence of seasonal variations on biological activities is important for pharmacological studies and metabolic engineering. Therefore, this study was conducted to determine the variation of the chemical composition of essential oils obtained from Nectandra megapotamica leaves, collected at different stages of plant development, as well as its influence on the biological activities. A total of 38 compounds were identified that accounted for 97–99.2% of the chemical composition of the oils. Major differences were observed in the monoterpenic fraction, representing 5.1% of the compounds identified in the productive rest phase to 37.1% in the blooming phase. Bicyclogermacrene and germacrene D were the predominant compounds identified in the oil of all collections. Furthermore, limonene, β-pinene, and spathulenol were identified predominantly in the samples of blooming and fruiting phases. The oils exhibited significant antichemotactic activity and different effects in scavenging the radical 2,2-diphenyl-1-picrylhydrazyl. Variations were also observed in the antifungal activity, with the minimum inhibitory concentrations ranging from 125 to 500 μg/mL. These results demonstrate the influence of monoterpenes, primarily limonene, α-pinene, and β-pinene, on the bioactivities of the oil. Studies investigating the variations in the chemical composition of essential oil may offer a strategy to produce a compound or a group of compounds of interest to industries with a specific pharmacological focus. |
publishDate |
2019 |
dc.date.accessioned.fl_str_mv |
2019-06-18T02:34:39Z |
dc.date.issued.fl_str_mv |
2019 |
dc.type.driver.fl_str_mv |
Estrangeiro info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10183/195870 |
dc.identifier.issn.pt_BR.fl_str_mv |
2218-273X |
dc.identifier.nrb.pt_BR.fl_str_mv |
001094577 |
identifier_str_mv |
2218-273X 001094577 |
url |
http://hdl.handle.net/10183/195870 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.pt_BR.fl_str_mv |
Biomolecules. Basel. Vol. 9, no. 3 (Mar. 2019), p. 1-12 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UFRGS instname:Universidade Federal do Rio Grande do Sul (UFRGS) instacron:UFRGS |
instname_str |
Universidade Federal do Rio Grande do Sul (UFRGS) |
instacron_str |
UFRGS |
institution |
UFRGS |
reponame_str |
Repositório Institucional da UFRGS |
collection |
Repositório Institucional da UFRGS |
bitstream.url.fl_str_mv |
http://www.lume.ufrgs.br/bitstream/10183/195870/2/001094577.pdf.txt http://www.lume.ufrgs.br/bitstream/10183/195870/1/001094577.pdf |
bitstream.checksum.fl_str_mv |
952448dc2553aa58191417149a667779 fb0ca001028ed9b7aead7a44c7f9ef1b |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 |
repository.name.fl_str_mv |
Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS) |
repository.mail.fl_str_mv |
|
_version_ |
1801224968683388928 |