Acaricides resistance in ticks : selection, diagnosis, mechanisms, and mitigation
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/243241 |
Resumo: | Ticks are blood-feeding ecto-parasites that have a cosmopolitan distribution in tropical and subtropical regions of the world. Ticks cause economic losses in the form of reduced blood, meat and dairy products, as well as pathogen transmission. Different acaricides such as organochlorines, organophosphates, formamidines (e.g. amitraz), synthetic pyrethroids, macrocyclic lactones, fipronil, and fluazuron are currently used sequentially or simultaneously to control tick infestations. Most acaricide treatments now face increasingly high chances of failure, due to the resistance selection in different tick populations against these drugs. Acaricide resistance in ticks can be developed in different ways, including amino acid substitutions that result in morphological changes in the acaricide target, metabolic detoxification, and reduced acaricide entry through the outer layer of the tick body. The current literature brings a plethora of information regarding the use of different acaricides for tick control, resistance selection, analysis of mutations in target sites, and resistance mitigation. Alternatives such as synergistic use of different acaricides, plant-derived phytochemicals, fungi as biological control agents, and anti-tick vaccines have been recommended to avoid and mitigate acaricide resistance. The purpose of this review was to summarize and discuss different acaricides applied for tick control, their mechanisms of action and resistance selection, genetic polymorphisms in their target molecules, as well as the approaches used for diagnosis and mitigation of acaricide resistance, specifically in Rhipicephalus microplus ticks. |
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Obaid, Muhammad KashifIslam, NabilaAlouffi, AbdulazizKhan, Alam ZebVaz Junior, Itabajara da SilvaTanaka, TetsuyaAli, Abid2022-07-20T04:49:40Z20222235-2988http://hdl.handle.net/10183/243241001145118Ticks are blood-feeding ecto-parasites that have a cosmopolitan distribution in tropical and subtropical regions of the world. Ticks cause economic losses in the form of reduced blood, meat and dairy products, as well as pathogen transmission. Different acaricides such as organochlorines, organophosphates, formamidines (e.g. amitraz), synthetic pyrethroids, macrocyclic lactones, fipronil, and fluazuron are currently used sequentially or simultaneously to control tick infestations. Most acaricide treatments now face increasingly high chances of failure, due to the resistance selection in different tick populations against these drugs. Acaricide resistance in ticks can be developed in different ways, including amino acid substitutions that result in morphological changes in the acaricide target, metabolic detoxification, and reduced acaricide entry through the outer layer of the tick body. The current literature brings a plethora of information regarding the use of different acaricides for tick control, resistance selection, analysis of mutations in target sites, and resistance mitigation. Alternatives such as synergistic use of different acaricides, plant-derived phytochemicals, fungi as biological control agents, and anti-tick vaccines have been recommended to avoid and mitigate acaricide resistance. The purpose of this review was to summarize and discuss different acaricides applied for tick control, their mechanisms of action and resistance selection, genetic polymorphisms in their target molecules, as well as the approaches used for diagnosis and mitigation of acaricide resistance, specifically in Rhipicephalus microplus ticks.application/pdfengFrontiers in Cellular and Infection Microbiology. Lausanne. Vol. 12 (July 2022), 941831, 20 p.AcaricidaResistência à pesticidaRhipicephalus microplusCarrapatoAcaricidesMitigationResistanceSNPsTicksAcaricides resistance in ticks : selection, diagnosis, mechanisms, and mitigationEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001145118.pdf.txt001145118.pdf.txtExtracted Texttext/plain122469http://www.lume.ufrgs.br/bitstream/10183/243241/2/001145118.pdf.txtec231eafc113a449207d1cc6740c83cdMD52ORIGINAL001145118.pdfTexto completo (inglês)application/pdf1706415http://www.lume.ufrgs.br/bitstream/10183/243241/1/001145118.pdfa7cc46b36a22bea1e397f335e69c2fdbMD5110183/2432412022-07-21 04:55:58.40294oai:www.lume.ufrgs.br:10183/243241Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2022-07-21T07:55:58Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Acaricides resistance in ticks : selection, diagnosis, mechanisms, and mitigation |
title |
Acaricides resistance in ticks : selection, diagnosis, mechanisms, and mitigation |
spellingShingle |
Acaricides resistance in ticks : selection, diagnosis, mechanisms, and mitigation Obaid, Muhammad Kashif Acaricida Resistência à pesticida Rhipicephalus microplus Carrapato Acaricides Mitigation Resistance SNPs Ticks |
title_short |
Acaricides resistance in ticks : selection, diagnosis, mechanisms, and mitigation |
title_full |
Acaricides resistance in ticks : selection, diagnosis, mechanisms, and mitigation |
title_fullStr |
Acaricides resistance in ticks : selection, diagnosis, mechanisms, and mitigation |
title_full_unstemmed |
Acaricides resistance in ticks : selection, diagnosis, mechanisms, and mitigation |
title_sort |
Acaricides resistance in ticks : selection, diagnosis, mechanisms, and mitigation |
author |
Obaid, Muhammad Kashif |
author_facet |
Obaid, Muhammad Kashif Islam, Nabila Alouffi, Abdulaziz Khan, Alam Zeb Vaz Junior, Itabajara da Silva Tanaka, Tetsuya Ali, Abid |
author_role |
author |
author2 |
Islam, Nabila Alouffi, Abdulaziz Khan, Alam Zeb Vaz Junior, Itabajara da Silva Tanaka, Tetsuya Ali, Abid |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Obaid, Muhammad Kashif Islam, Nabila Alouffi, Abdulaziz Khan, Alam Zeb Vaz Junior, Itabajara da Silva Tanaka, Tetsuya Ali, Abid |
dc.subject.por.fl_str_mv |
Acaricida Resistência à pesticida Rhipicephalus microplus Carrapato |
topic |
Acaricida Resistência à pesticida Rhipicephalus microplus Carrapato Acaricides Mitigation Resistance SNPs Ticks |
dc.subject.eng.fl_str_mv |
Acaricides Mitigation Resistance SNPs Ticks |
description |
Ticks are blood-feeding ecto-parasites that have a cosmopolitan distribution in tropical and subtropical regions of the world. Ticks cause economic losses in the form of reduced blood, meat and dairy products, as well as pathogen transmission. Different acaricides such as organochlorines, organophosphates, formamidines (e.g. amitraz), synthetic pyrethroids, macrocyclic lactones, fipronil, and fluazuron are currently used sequentially or simultaneously to control tick infestations. Most acaricide treatments now face increasingly high chances of failure, due to the resistance selection in different tick populations against these drugs. Acaricide resistance in ticks can be developed in different ways, including amino acid substitutions that result in morphological changes in the acaricide target, metabolic detoxification, and reduced acaricide entry through the outer layer of the tick body. The current literature brings a plethora of information regarding the use of different acaricides for tick control, resistance selection, analysis of mutations in target sites, and resistance mitigation. Alternatives such as synergistic use of different acaricides, plant-derived phytochemicals, fungi as biological control agents, and anti-tick vaccines have been recommended to avoid and mitigate acaricide resistance. The purpose of this review was to summarize and discuss different acaricides applied for tick control, their mechanisms of action and resistance selection, genetic polymorphisms in their target molecules, as well as the approaches used for diagnosis and mitigation of acaricide resistance, specifically in Rhipicephalus microplus ticks. |
publishDate |
2022 |
dc.date.accessioned.fl_str_mv |
2022-07-20T04:49:40Z |
dc.date.issued.fl_str_mv |
2022 |
dc.type.driver.fl_str_mv |
Estrangeiro info:eu-repo/semantics/article |
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http://hdl.handle.net/10183/243241 |
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2235-2988 |
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001145118 |
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http://hdl.handle.net/10183/243241 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.pt_BR.fl_str_mv |
Frontiers in Cellular and Infection Microbiology. Lausanne. Vol. 12 (July 2022), 941831, 20 p. |
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info:eu-repo/semantics/openAccess |
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openAccess |
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