Desenvolvimento de métodos de análise por clae-uv para os antimicrobianos tetraciclina, sulfametoxazol e trimetoprima utilizando materiais à base de sílica como sistemas de pré-concentração

• Autor(a) principal: Pedroso, Rosana Cristina Ribeiro
• Data de Publicação: 2011
• Outros Autores: Peralba, Maria do Carmo Ruaro, Santos, Joao Henrique Zimnoch dos, Pizzolato, Tania Mara, Froehlich, Pedro Eduardo
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da UFRGS
• Texto Completo: http://hdl.handle.net/10183/72913
• topic: Antimicrobianos; Trimetoprima; Tetraciclina; Sulfametoxazol; Extração em fase sólida; Sílica; Antimicrobians; Silica-based material; Solid-phase extraction

This paper evaluates the adsorption capacity of zirconocene-based silica materials in the preconcentration of antimicrobians (tetracycline, sulfamethoxazole and trimethoprim) in aqueous medium. These materials were prepared by grafting the zirconocene onto silicas pre-treated at different temperatures. The retention capacity of these materials was evaluated by off line SPE and HPLC-UV and the proposed methodology was validated in ultrapure, tap and river water. The recovery for tetracycline was 72% (in the solid phase A) and, for sulfamethoxazole and trimethoprim was 68 and 95% in the commercial C18, respectively. The target antimicrobians were not detected in the Arroio Diluvio (Porto Alegre . RS).