Stem cells to improve the wound healing

Detalhes bibliográficos
Autor(a) principal: Vidor, Silvana Bellini
Data de Publicação: 2018
Outros Autores: Contesini, Emerson Antônio
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFRGS
Texto Completo: http://hdl.handle.net/10183/198937
Resumo: The cellular therapy using Mesenchymal Stem Cells, specially its two subtypes - Bone-marrow Mesenchymal Stem Cells and Adipose Derived Stem Cells - can benefit by virtue of the possibility of differentiating in specialized cells that secrete and suppress growing factors and cytokines necessary in the lesion niche. When attracted by the pro-inflammatory sinalization of the lesion, they act using the paracrine signaling, decreasing the inflammation, increasing the angiogenesis and the cell migration and proliferation. The development in the researches regarding the association of the application of MSCs, with reconstructive surgery practices, leads to effective future results that can bring more benefits to the clinic practice of this field. This paper has the objective of briefly reviewing the literature about the usage of MSCs and its subtypes, the ADSCs, to improve the skin cicatrization.
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spelling Vidor, Silvana BelliniContesini, Emerson Antônio2019-09-07T02:33:24Z20182577-2864http://hdl.handle.net/10183/198937001099551The cellular therapy using Mesenchymal Stem Cells, specially its two subtypes - Bone-marrow Mesenchymal Stem Cells and Adipose Derived Stem Cells - can benefit by virtue of the possibility of differentiating in specialized cells that secrete and suppress growing factors and cytokines necessary in the lesion niche. When attracted by the pro-inflammatory sinalization of the lesion, they act using the paracrine signaling, decreasing the inflammation, increasing the angiogenesis and the cell migration and proliferation. The development in the researches regarding the association of the application of MSCs, with reconstructive surgery practices, leads to effective future results that can bring more benefits to the clinic practice of this field. This paper has the objective of briefly reviewing the literature about the usage of MSCs and its subtypes, the ADSCs, to improve the skin cicatrization.application/pdfengJournal of head neck & spine surgery. Newbury Park. Vol. 3, no. 1 (May 2018), 555601, 5 p.Células-tronco mesenquimaisCicatrização de feridasMesenchymal stem cellsAdipose derived stem cellsBone-marrow mesenchymal stem cellsSkin flapsSkin graftsWound contractionParacrine signalingPro-inflammatory InterleukinsAnti-inflammatory InterleukinsStem cells to improve the wound healingEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001099551.pdf.txt001099551.pdf.txtExtracted Texttext/plain21692http://www.lume.ufrgs.br/bitstream/10183/198937/2/001099551.pdf.txt0fa7c510e75ba47c8c10fd74a427cc9cMD52ORIGINAL001099551.pdfTexto completo (inglês)application/pdf563924http://www.lume.ufrgs.br/bitstream/10183/198937/1/001099551.pdf1226e7c7af834e2b73065d929b368832MD5110183/1989372019-09-08 02:31:08.853893oai:www.lume.ufrgs.br:10183/198937Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2019-09-08T05:31:08Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.pt_BR.fl_str_mv Stem cells to improve the wound healing
title Stem cells to improve the wound healing
spellingShingle Stem cells to improve the wound healing
Vidor, Silvana Bellini
Células-tronco mesenquimais
Cicatrização de feridas
Mesenchymal stem cells
Adipose derived stem cells
Bone-marrow mesenchymal stem cells
Skin flaps
Skin grafts
Wound contraction
Paracrine signaling
Pro-inflammatory Interleukins
Anti-inflammatory Interleukins
title_short Stem cells to improve the wound healing
title_full Stem cells to improve the wound healing
title_fullStr Stem cells to improve the wound healing
title_full_unstemmed Stem cells to improve the wound healing
title_sort Stem cells to improve the wound healing
author Vidor, Silvana Bellini
author_facet Vidor, Silvana Bellini
Contesini, Emerson Antônio
author_role author
author2 Contesini, Emerson Antônio
author2_role author
dc.contributor.author.fl_str_mv Vidor, Silvana Bellini
Contesini, Emerson Antônio
dc.subject.por.fl_str_mv Células-tronco mesenquimais
Cicatrização de feridas
topic Células-tronco mesenquimais
Cicatrização de feridas
Mesenchymal stem cells
Adipose derived stem cells
Bone-marrow mesenchymal stem cells
Skin flaps
Skin grafts
Wound contraction
Paracrine signaling
Pro-inflammatory Interleukins
Anti-inflammatory Interleukins
dc.subject.eng.fl_str_mv Mesenchymal stem cells
Adipose derived stem cells
Bone-marrow mesenchymal stem cells
Skin flaps
Skin grafts
Wound contraction
Paracrine signaling
Pro-inflammatory Interleukins
Anti-inflammatory Interleukins
description The cellular therapy using Mesenchymal Stem Cells, specially its two subtypes - Bone-marrow Mesenchymal Stem Cells and Adipose Derived Stem Cells - can benefit by virtue of the possibility of differentiating in specialized cells that secrete and suppress growing factors and cytokines necessary in the lesion niche. When attracted by the pro-inflammatory sinalization of the lesion, they act using the paracrine signaling, decreasing the inflammation, increasing the angiogenesis and the cell migration and proliferation. The development in the researches regarding the association of the application of MSCs, with reconstructive surgery practices, leads to effective future results that can bring more benefits to the clinic practice of this field. This paper has the objective of briefly reviewing the literature about the usage of MSCs and its subtypes, the ADSCs, to improve the skin cicatrization.
publishDate 2018
dc.date.issued.fl_str_mv 2018
dc.date.accessioned.fl_str_mv 2019-09-07T02:33:24Z
dc.type.driver.fl_str_mv Estrangeiro
info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10183/198937
dc.identifier.issn.pt_BR.fl_str_mv 2577-2864
dc.identifier.nrb.pt_BR.fl_str_mv 001099551
identifier_str_mv 2577-2864
001099551
url http://hdl.handle.net/10183/198937
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.pt_BR.fl_str_mv Journal of head neck & spine surgery. Newbury Park. Vol. 3, no. 1 (May 2018), 555601, 5 p.
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFRGS
instname:Universidade Federal do Rio Grande do Sul (UFRGS)
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instname_str Universidade Federal do Rio Grande do Sul (UFRGS)
instacron_str UFRGS
institution UFRGS
reponame_str Repositório Institucional da UFRGS
collection Repositório Institucional da UFRGS
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