Risk factors for neonatal mortality in preterm newborns in the extreme south of Brazil
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/210694 |
Resumo: | Neonatal mortality still remains a complex challenge to be addressed. In Brazil, 60% of neonatal deaths occur among preterm infants with a gestational age of 32 weeks or less (≤32w). The aim of this study was to evaluate the factors involved in the high mortality rates among newborns with a gestational age ≤32w in a socioeconomically developed southern city in Brazil. Data on retrospective births and deaths (2000–2014) were analyzed from two ofcial Brazilian national databases. The risk of neonatal death for all independent variables (mother’s age and schooling, prenatal visits, birth hospital, delivery method, gestational age, and the newborn’s sex, age, and birth year, gemelarity, congenital anomalies and birthplace) was assessed with a univariable and a multivariable model of Cox’s semiparametric proportional hazards regression (p<0.05). Data of 288,904 newborns were included, being 4,514 with a gestational age ≤32w. The proportion of these early newborns remained stable among all births, while the neonatal mortality rate for this group tended to decrease (p<0.001). The adjusted risk was signifcantly for lower birthweight infants (mean 659.13g) born from Caesarean (HR 0.58 [95% CI 0.47–0.71]), but it was signifcantly higher for heavier birth weight infants (mean 2,087.79) also born via Caesarean section (HR 3.71 [95% CI 1.5–9.15]). Newborns with lower weight seemed to beneft most from Cesarean deliveries. Efort towards reducing unacceptably high surgical deliveries must take into account cases that the operations may be lifesaving for mother and/or the baby. |
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Tietzmann, Marcos RobertoTeichmann, Pedro do ValleVilanova, Cássia SimeãoGoldani, Marcelo ZubaranSilva, Clecio Homrich da2020-06-27T03:39:37Z20202045-2322http://hdl.handle.net/10183/210694001114520Neonatal mortality still remains a complex challenge to be addressed. In Brazil, 60% of neonatal deaths occur among preterm infants with a gestational age of 32 weeks or less (≤32w). The aim of this study was to evaluate the factors involved in the high mortality rates among newborns with a gestational age ≤32w in a socioeconomically developed southern city in Brazil. Data on retrospective births and deaths (2000–2014) were analyzed from two ofcial Brazilian national databases. The risk of neonatal death for all independent variables (mother’s age and schooling, prenatal visits, birth hospital, delivery method, gestational age, and the newborn’s sex, age, and birth year, gemelarity, congenital anomalies and birthplace) was assessed with a univariable and a multivariable model of Cox’s semiparametric proportional hazards regression (p<0.05). Data of 288,904 newborns were included, being 4,514 with a gestational age ≤32w. The proportion of these early newborns remained stable among all births, while the neonatal mortality rate for this group tended to decrease (p<0.001). The adjusted risk was signifcantly for lower birthweight infants (mean 659.13g) born from Caesarean (HR 0.58 [95% CI 0.47–0.71]), but it was signifcantly higher for heavier birth weight infants (mean 2,087.79) also born via Caesarean section (HR 3.71 [95% CI 1.5–9.15]). Newborns with lower weight seemed to beneft most from Cesarean deliveries. Efort towards reducing unacceptably high surgical deliveries must take into account cases that the operations may be lifesaving for mother and/or the baby.application/pdfengScientific reports. London. Vol. 10 (2020), 7252,7 p.Mortalidade infantilRecém-nascidoFatores de riscoBrasilRisk factors for neonatal mortality in preterm newborns in the extreme south of BrazilEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001114520.pdf.txt001114520.pdf.txtExtracted Texttext/plain39027http://www.lume.ufrgs.br/bitstream/10183/210694/2/001114520.pdf.txtf057402803e0189736bec86bf80f13c1MD52ORIGINAL001114520.pdfTexto completo (inglês)application/pdf1170516http://www.lume.ufrgs.br/bitstream/10183/210694/1/001114520.pdfa4bc14d30ada921658d3edcd5fcfd981MD5110183/2106942020-06-28 03:33:59.866192oai:www.lume.ufrgs.br:10183/210694Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2020-06-28T06:33:59Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Risk factors for neonatal mortality in preterm newborns in the extreme south of Brazil |
title |
Risk factors for neonatal mortality in preterm newborns in the extreme south of Brazil |
spellingShingle |
Risk factors for neonatal mortality in preterm newborns in the extreme south of Brazil Tietzmann, Marcos Roberto Mortalidade infantil Recém-nascido Fatores de risco Brasil |
title_short |
Risk factors for neonatal mortality in preterm newborns in the extreme south of Brazil |
title_full |
Risk factors for neonatal mortality in preterm newborns in the extreme south of Brazil |
title_fullStr |
Risk factors for neonatal mortality in preterm newborns in the extreme south of Brazil |
title_full_unstemmed |
Risk factors for neonatal mortality in preterm newborns in the extreme south of Brazil |
title_sort |
Risk factors for neonatal mortality in preterm newborns in the extreme south of Brazil |
author |
Tietzmann, Marcos Roberto |
author_facet |
Tietzmann, Marcos Roberto Teichmann, Pedro do Valle Vilanova, Cássia Simeão Goldani, Marcelo Zubaran Silva, Clecio Homrich da |
author_role |
author |
author2 |
Teichmann, Pedro do Valle Vilanova, Cássia Simeão Goldani, Marcelo Zubaran Silva, Clecio Homrich da |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Tietzmann, Marcos Roberto Teichmann, Pedro do Valle Vilanova, Cássia Simeão Goldani, Marcelo Zubaran Silva, Clecio Homrich da |
dc.subject.por.fl_str_mv |
Mortalidade infantil Recém-nascido Fatores de risco Brasil |
topic |
Mortalidade infantil Recém-nascido Fatores de risco Brasil |
description |
Neonatal mortality still remains a complex challenge to be addressed. In Brazil, 60% of neonatal deaths occur among preterm infants with a gestational age of 32 weeks or less (≤32w). The aim of this study was to evaluate the factors involved in the high mortality rates among newborns with a gestational age ≤32w in a socioeconomically developed southern city in Brazil. Data on retrospective births and deaths (2000–2014) were analyzed from two ofcial Brazilian national databases. The risk of neonatal death for all independent variables (mother’s age and schooling, prenatal visits, birth hospital, delivery method, gestational age, and the newborn’s sex, age, and birth year, gemelarity, congenital anomalies and birthplace) was assessed with a univariable and a multivariable model of Cox’s semiparametric proportional hazards regression (p<0.05). Data of 288,904 newborns were included, being 4,514 with a gestational age ≤32w. The proportion of these early newborns remained stable among all births, while the neonatal mortality rate for this group tended to decrease (p<0.001). The adjusted risk was signifcantly for lower birthweight infants (mean 659.13g) born from Caesarean (HR 0.58 [95% CI 0.47–0.71]), but it was signifcantly higher for heavier birth weight infants (mean 2,087.79) also born via Caesarean section (HR 3.71 [95% CI 1.5–9.15]). Newborns with lower weight seemed to beneft most from Cesarean deliveries. Efort towards reducing unacceptably high surgical deliveries must take into account cases that the operations may be lifesaving for mother and/or the baby. |
publishDate |
2020 |
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2020-06-27T03:39:37Z |
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2020 |
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http://hdl.handle.net/10183/210694 |
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2045-2322 |
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001114520 |
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Scientific reports. London. Vol. 10 (2020), 7252,7 p. |
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