Necrotizing fasciitis in the puerperium of a woman with complement deficiency : case report and review literature
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/188817 |
Resumo: | Complement deficiencies are uncommon types of primary immunodeficiency. Necrotizing fasciitis is a rare complication in pregnancy characterized by soft tissue invasion and necrosis of the subcutaneous and other adjacent tissues, leading to high mortality rates. We report a case of a 29-year-old pregnant woman with functional deficiency of the C4 complement component and short uterine cervix. Admitted at the hospital with preterm labor, she received multiple doses of immunoglobulin. After 8 weeks, she had a premature membrane rupture, and due to pelvic presentation she had a cesarean. The patient presented multiple obstetric complications, such as operative wound infection, endometritis, sepsis, necrotizing fasciitis and pelvic septic thrombophlebitis. She underwent multiple antimicrobial schemes, a hysterectomy and 4 extensive debridements of the abdominal wall because of significant necrosis. She stayed at the hospital for 101 days (32 of those in ICU in immediate postpartum). 41 days after cesarean, patient was discharged in good conditions. Our case emphasizes individual handling and high multiple doses of immunoglobulin for favorable outcome of the case. |
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Vettorazzi, JaneteValério, Edimárlei GonsalesFaulhaber, Gustavo Adolpho MoreiraPerez, Amanda VilaverdeSilva, Mariana Sbaraini daVettori, Daniela Vanessa2019-02-15T02:33:50Z20182160-8806http://hdl.handle.net/10183/188817001084865Complement deficiencies are uncommon types of primary immunodeficiency. Necrotizing fasciitis is a rare complication in pregnancy characterized by soft tissue invasion and necrosis of the subcutaneous and other adjacent tissues, leading to high mortality rates. We report a case of a 29-year-old pregnant woman with functional deficiency of the C4 complement component and short uterine cervix. Admitted at the hospital with preterm labor, she received multiple doses of immunoglobulin. After 8 weeks, she had a premature membrane rupture, and due to pelvic presentation she had a cesarean. The patient presented multiple obstetric complications, such as operative wound infection, endometritis, sepsis, necrotizing fasciitis and pelvic septic thrombophlebitis. She underwent multiple antimicrobial schemes, a hysterectomy and 4 extensive debridements of the abdominal wall because of significant necrosis. She stayed at the hospital for 101 days (32 of those in ICU in immediate postpartum). 41 days after cesarean, patient was discharged in good conditions. Our case emphasizes individual handling and high multiple doses of immunoglobulin for favorable outcome of the case.application/pdfengOpen Journal of Obstetrics and Gynecology. Irvine. vol. 8, no. 12 (2018), 88057, p. 1236-1246GravidezFasciite necrosanteImunidadePregnancyC4 FactorImmunodeficiencyC4 DeficiencyNecrotizing FasciitisPuerperal InfectionNecrotizing fasciitis in the puerperium of a woman with complement deficiency : case report and review literatureEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001084865.pdf.txt001084865.pdf.txtExtracted Texttext/plain30321http://www.lume.ufrgs.br/bitstream/10183/188817/2/001084865.pdf.txt3c7901e487f92fb27fcecc5e65923da1MD52ORIGINAL001084865.pdfTexto completo (inglês)application/pdf726448http://www.lume.ufrgs.br/bitstream/10183/188817/1/001084865.pdf6f0abac0a42a6a2bfa9cf7adda0e436aMD5110183/1888172019-02-16 02:34:32.162257oai:www.lume.ufrgs.br:10183/188817Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2019-02-16T04:34:32Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Necrotizing fasciitis in the puerperium of a woman with complement deficiency : case report and review literature |
title |
Necrotizing fasciitis in the puerperium of a woman with complement deficiency : case report and review literature |
spellingShingle |
Necrotizing fasciitis in the puerperium of a woman with complement deficiency : case report and review literature Vettorazzi, Janete Gravidez Fasciite necrosante Imunidade Pregnancy C4 Factor Immunodeficiency C4 Deficiency Necrotizing Fasciitis Puerperal Infection |
title_short |
Necrotizing fasciitis in the puerperium of a woman with complement deficiency : case report and review literature |
title_full |
Necrotizing fasciitis in the puerperium of a woman with complement deficiency : case report and review literature |
title_fullStr |
Necrotizing fasciitis in the puerperium of a woman with complement deficiency : case report and review literature |
title_full_unstemmed |
Necrotizing fasciitis in the puerperium of a woman with complement deficiency : case report and review literature |
title_sort |
Necrotizing fasciitis in the puerperium of a woman with complement deficiency : case report and review literature |
author |
Vettorazzi, Janete |
author_facet |
Vettorazzi, Janete Valério, Edimárlei Gonsales Faulhaber, Gustavo Adolpho Moreira Perez, Amanda Vilaverde Silva, Mariana Sbaraini da Vettori, Daniela Vanessa |
author_role |
author |
author2 |
Valério, Edimárlei Gonsales Faulhaber, Gustavo Adolpho Moreira Perez, Amanda Vilaverde Silva, Mariana Sbaraini da Vettori, Daniela Vanessa |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Vettorazzi, Janete Valério, Edimárlei Gonsales Faulhaber, Gustavo Adolpho Moreira Perez, Amanda Vilaverde Silva, Mariana Sbaraini da Vettori, Daniela Vanessa |
dc.subject.por.fl_str_mv |
Gravidez Fasciite necrosante Imunidade |
topic |
Gravidez Fasciite necrosante Imunidade Pregnancy C4 Factor Immunodeficiency C4 Deficiency Necrotizing Fasciitis Puerperal Infection |
dc.subject.eng.fl_str_mv |
Pregnancy C4 Factor Immunodeficiency C4 Deficiency Necrotizing Fasciitis Puerperal Infection |
description |
Complement deficiencies are uncommon types of primary immunodeficiency. Necrotizing fasciitis is a rare complication in pregnancy characterized by soft tissue invasion and necrosis of the subcutaneous and other adjacent tissues, leading to high mortality rates. We report a case of a 29-year-old pregnant woman with functional deficiency of the C4 complement component and short uterine cervix. Admitted at the hospital with preterm labor, she received multiple doses of immunoglobulin. After 8 weeks, she had a premature membrane rupture, and due to pelvic presentation she had a cesarean. The patient presented multiple obstetric complications, such as operative wound infection, endometritis, sepsis, necrotizing fasciitis and pelvic septic thrombophlebitis. She underwent multiple antimicrobial schemes, a hysterectomy and 4 extensive debridements of the abdominal wall because of significant necrosis. She stayed at the hospital for 101 days (32 of those in ICU in immediate postpartum). 41 days after cesarean, patient was discharged in good conditions. Our case emphasizes individual handling and high multiple doses of immunoglobulin for favorable outcome of the case. |
publishDate |
2018 |
dc.date.issued.fl_str_mv |
2018 |
dc.date.accessioned.fl_str_mv |
2019-02-15T02:33:50Z |
dc.type.driver.fl_str_mv |
Estrangeiro info:eu-repo/semantics/article |
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publishedVersion |
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http://hdl.handle.net/10183/188817 |
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2160-8806 |
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001084865 |
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http://hdl.handle.net/10183/188817 |
dc.language.iso.fl_str_mv |
eng |
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eng |
dc.relation.ispartof.pt_BR.fl_str_mv |
Open Journal of Obstetrics and Gynecology. Irvine. vol. 8, no. 12 (2018), 88057, p. 1236-1246 |
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info:eu-repo/semantics/openAccess |
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