Prevalence and acquisition of MRSA amongst patients admitted to a tertiary-care hospital in Brazil
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/30378 |
Resumo: | Background: There are few studies in Brazil that address baseline prevalence of MRSA colonization and associated risk factors at hospital admission, or the incidence of nosocomial colonization. We report a prospective study in a tertiary-care, university-affiliated hospital to implement a new MRSA control policy at the institution. Methods: A cohort of randomly selected patients admitted to emergency and clinical wards at our hospital was followed until discharge. Nasal swabs were taken for identification of MRSA-colonized patients and detection of SCCmecA in positive cultures, at admission and weekly thereafter. Multivariate analysis using a log-binomial analysis was used to identify risk factors for colonization. Results: After screening 297 adult patients and 176 pediatric patients, the prevalence of MRSA at admission was 6.1% (95%CI, 3.6% to 9.4%), in the adult population and 2.3% (95%CI, 0.6% to 5.7%), for children. From multivariate analysis, the risk factors associated with colonization in adults were: age above 60 years (P = 0.019) and hospitalization in the previous year (P = 0.022). Incidence analysis was performed in 276 MRSA-negative patients (175 adults and 101 children). Acquisition rate was 5.5/1,000 patient-days for adults (95%CI, 3.4 to 8.5/1,000 patients-days), and 1.1/1,000 patient-days for children (95%CI, 0.1 to 4.0/1,000 patients-days). Conclusions: The identification of MRSA carriers is a step towards establishing a control policy for MRSA, and helps to identify measures needed to reduce colonization pressure and to decrease the high acquisition rate in hospitalized patients. |
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Santos, Helena Barreto dosMachado, Denise PiresCamey, Suzi AlvesKuchenbecker, Ricardo de SouzaBarth, Afonso LuisWagner, Mario Bernardes2011-07-27T06:00:48Z20101471-2334http://hdl.handle.net/10183/30378000777002Background: There are few studies in Brazil that address baseline prevalence of MRSA colonization and associated risk factors at hospital admission, or the incidence of nosocomial colonization. We report a prospective study in a tertiary-care, university-affiliated hospital to implement a new MRSA control policy at the institution. Methods: A cohort of randomly selected patients admitted to emergency and clinical wards at our hospital was followed until discharge. Nasal swabs were taken for identification of MRSA-colonized patients and detection of SCCmecA in positive cultures, at admission and weekly thereafter. Multivariate analysis using a log-binomial analysis was used to identify risk factors for colonization. Results: After screening 297 adult patients and 176 pediatric patients, the prevalence of MRSA at admission was 6.1% (95%CI, 3.6% to 9.4%), in the adult population and 2.3% (95%CI, 0.6% to 5.7%), for children. From multivariate analysis, the risk factors associated with colonization in adults were: age above 60 years (P = 0.019) and hospitalization in the previous year (P = 0.022). Incidence analysis was performed in 276 MRSA-negative patients (175 adults and 101 children). Acquisition rate was 5.5/1,000 patient-days for adults (95%CI, 3.4 to 8.5/1,000 patients-days), and 1.1/1,000 patient-days for children (95%CI, 0.1 to 4.0/1,000 patients-days). Conclusions: The identification of MRSA carriers is a step towards establishing a control policy for MRSA, and helps to identify measures needed to reduce colonization pressure and to decrease the high acquisition rate in hospitalized patients.application/pdfengBMC infectious diseases. London. Vol. 10 (14 nov. 2010), p. 328 (7 p.)EpidemiologiaInfecção hospitalarHospitais universitáriosEstatística e dados numéricosIncidênciaStaphylococcus aureus resistente à meticilinaPrevalênciaEstudos prospectivosFatores de riscoInfecções estafilocócicasBrasilPrevalence and acquisition of MRSA amongst patients admitted to a tertiary-care hospital in BrazilEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL000777002.pdf000777002.pdfTexto completo (inglês)application/pdf223643http://www.lume.ufrgs.br/bitstream/10183/30378/1/000777002.pdfca9470be6e990483204a4b395226d623MD51TEXT000777002.pdf.txt000777002.pdf.txtExtracted Texttext/plain35075http://www.lume.ufrgs.br/bitstream/10183/30378/2/000777002.pdf.txt89bdc685730af41f9666abc7110f2e2bMD52THUMBNAIL000777002.pdf.jpg000777002.pdf.jpgGenerated Thumbnailimage/jpeg2008http://www.lume.ufrgs.br/bitstream/10183/30378/3/000777002.pdf.jpga9246fe042ef6f08ba03f79919cfd6b8MD5310183/303782023-11-05 04:25:36.318039oai:www.lume.ufrgs.br:10183/30378Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2023-11-05T06:25:36Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Prevalence and acquisition of MRSA amongst patients admitted to a tertiary-care hospital in Brazil |
title |
Prevalence and acquisition of MRSA amongst patients admitted to a tertiary-care hospital in Brazil |
spellingShingle |
Prevalence and acquisition of MRSA amongst patients admitted to a tertiary-care hospital in Brazil Santos, Helena Barreto dos Epidemiologia Infecção hospitalar Hospitais universitários Estatística e dados numéricos Incidência Staphylococcus aureus resistente à meticilina Prevalência Estudos prospectivos Fatores de risco Infecções estafilocócicas Brasil |
title_short |
Prevalence and acquisition of MRSA amongst patients admitted to a tertiary-care hospital in Brazil |
title_full |
Prevalence and acquisition of MRSA amongst patients admitted to a tertiary-care hospital in Brazil |
title_fullStr |
Prevalence and acquisition of MRSA amongst patients admitted to a tertiary-care hospital in Brazil |
title_full_unstemmed |
Prevalence and acquisition of MRSA amongst patients admitted to a tertiary-care hospital in Brazil |
title_sort |
Prevalence and acquisition of MRSA amongst patients admitted to a tertiary-care hospital in Brazil |
author |
Santos, Helena Barreto dos |
author_facet |
Santos, Helena Barreto dos Machado, Denise Pires Camey, Suzi Alves Kuchenbecker, Ricardo de Souza Barth, Afonso Luis Wagner, Mario Bernardes |
author_role |
author |
author2 |
Machado, Denise Pires Camey, Suzi Alves Kuchenbecker, Ricardo de Souza Barth, Afonso Luis Wagner, Mario Bernardes |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Santos, Helena Barreto dos Machado, Denise Pires Camey, Suzi Alves Kuchenbecker, Ricardo de Souza Barth, Afonso Luis Wagner, Mario Bernardes |
dc.subject.por.fl_str_mv |
Epidemiologia Infecção hospitalar Hospitais universitários Estatística e dados numéricos Incidência Staphylococcus aureus resistente à meticilina Prevalência Estudos prospectivos Fatores de risco Infecções estafilocócicas Brasil |
topic |
Epidemiologia Infecção hospitalar Hospitais universitários Estatística e dados numéricos Incidência Staphylococcus aureus resistente à meticilina Prevalência Estudos prospectivos Fatores de risco Infecções estafilocócicas Brasil |
description |
Background: There are few studies in Brazil that address baseline prevalence of MRSA colonization and associated risk factors at hospital admission, or the incidence of nosocomial colonization. We report a prospective study in a tertiary-care, university-affiliated hospital to implement a new MRSA control policy at the institution. Methods: A cohort of randomly selected patients admitted to emergency and clinical wards at our hospital was followed until discharge. Nasal swabs were taken for identification of MRSA-colonized patients and detection of SCCmecA in positive cultures, at admission and weekly thereafter. Multivariate analysis using a log-binomial analysis was used to identify risk factors for colonization. Results: After screening 297 adult patients and 176 pediatric patients, the prevalence of MRSA at admission was 6.1% (95%CI, 3.6% to 9.4%), in the adult population and 2.3% (95%CI, 0.6% to 5.7%), for children. From multivariate analysis, the risk factors associated with colonization in adults were: age above 60 years (P = 0.019) and hospitalization in the previous year (P = 0.022). Incidence analysis was performed in 276 MRSA-negative patients (175 adults and 101 children). Acquisition rate was 5.5/1,000 patient-days for adults (95%CI, 3.4 to 8.5/1,000 patients-days), and 1.1/1,000 patient-days for children (95%CI, 0.1 to 4.0/1,000 patients-days). Conclusions: The identification of MRSA carriers is a step towards establishing a control policy for MRSA, and helps to identify measures needed to reduce colonization pressure and to decrease the high acquisition rate in hospitalized patients. |
publishDate |
2010 |
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2010 |
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1471-2334 |
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000777002 |
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BMC infectious diseases. London. Vol. 10 (14 nov. 2010), p. 328 (7 p.) |
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