Virginia Woolf, neuroprogression, and bipolar disorder
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/163556 |
Resumo: | Family history and traumatic experiences are factors linked to bipolar disorder. It is known that the lifetime risk of bipolar disorder in relatives of a bipolar proband are 5-10% for first degree relatives and 40-70% for monozygotic co-twins. It is also known that patients with early childhood trauma present earlier onset of bipolar disorder, increased number of manic episodes, and more suicide attempts. We have recently reported that childhood trauma partly mediates the effect of family history on bipolar disorder diagnosis. In light of these findings from the scientific literature, we reviewed the work of British writer Virginia Woolf, who allegedly suffered from bipolar disorder. Her disorder was strongly related to her family background. Moreover, Virginia Woolf was sexually molested by her half siblings for nine years. Her bipolar disorder symptoms presented a pernicious course, associated with hospitalizations, suicidal behavioral, and functional impairment. The concept of neuroprogression has been used to explain the clinical deterioration that takes places in a subgroup of bipolar disorder patients. The examination of Virgina Woolf’s biography and art can provide clinicians with important insights about the course of bipolar disorder. |
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Boeira, Manuela ViannaBerni, Gabriela de ÁvilaPassos, Ives CavalcanteKauer-Sant'Anna, MárciaKapczinski, Flávio Pereira2017-06-28T02:29:20Z20171516-4446http://hdl.handle.net/10183/163556001017675Family history and traumatic experiences are factors linked to bipolar disorder. It is known that the lifetime risk of bipolar disorder in relatives of a bipolar proband are 5-10% for first degree relatives and 40-70% for monozygotic co-twins. It is also known that patients with early childhood trauma present earlier onset of bipolar disorder, increased number of manic episodes, and more suicide attempts. We have recently reported that childhood trauma partly mediates the effect of family history on bipolar disorder diagnosis. In light of these findings from the scientific literature, we reviewed the work of British writer Virginia Woolf, who allegedly suffered from bipolar disorder. Her disorder was strongly related to her family background. Moreover, Virginia Woolf was sexually molested by her half siblings for nine years. Her bipolar disorder symptoms presented a pernicious course, associated with hospitalizations, suicidal behavioral, and functional impairment. The concept of neuroprogression has been used to explain the clinical deterioration that takes places in a subgroup of bipolar disorder patients. The examination of Virgina Woolf’s biography and art can provide clinicians with important insights about the course of bipolar disorder.application/pdfengRevista brasileira de psiquiatria (1999). São Paulo. Vol. 39, n. 1 (jan./mar. 2017), p. 69–71Transtornos do humorTranstorno bipolarEstresse psicológicoMood disordersBipolarSuicideStressSexual assaultCognitive neuroscienceVirginia Woolf, neuroprogression, and bipolar disorderinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/otherinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL001017675.pdf001017675.pdfTexto completo (inglês)application/pdf59145http://www.lume.ufrgs.br/bitstream/10183/163556/1/001017675.pdf2fe184cf5c85b2e4d335d58420286b7bMD51TEXT001017675.pdf.txt001017675.pdf.txtExtracted Texttext/plain17966http://www.lume.ufrgs.br/bitstream/10183/163556/2/001017675.pdf.txt9955ac31e8769f06afeab22af3dc6a6eMD52THUMBNAIL001017675.pdf.jpg001017675.pdf.jpgGenerated Thumbnailimage/jpeg2031http://www.lume.ufrgs.br/bitstream/10183/163556/3/001017675.pdf.jpg0ac4f921bf6884ddaa86c4ef41629f38MD5310183/1635562022-09-23 04:41:44.307993oai:www.lume.ufrgs.br:10183/163556Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2022-09-23T07:41:44Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Virginia Woolf, neuroprogression, and bipolar disorder |
title |
Virginia Woolf, neuroprogression, and bipolar disorder |
spellingShingle |
Virginia Woolf, neuroprogression, and bipolar disorder Boeira, Manuela Vianna Transtornos do humor Transtorno bipolar Estresse psicológico Mood disorders Bipolar Suicide Stress Sexual assault Cognitive neuroscience |
title_short |
Virginia Woolf, neuroprogression, and bipolar disorder |
title_full |
Virginia Woolf, neuroprogression, and bipolar disorder |
title_fullStr |
Virginia Woolf, neuroprogression, and bipolar disorder |
title_full_unstemmed |
Virginia Woolf, neuroprogression, and bipolar disorder |
title_sort |
Virginia Woolf, neuroprogression, and bipolar disorder |
author |
Boeira, Manuela Vianna |
author_facet |
Boeira, Manuela Vianna Berni, Gabriela de Ávila Passos, Ives Cavalcante Kauer-Sant'Anna, Márcia Kapczinski, Flávio Pereira |
author_role |
author |
author2 |
Berni, Gabriela de Ávila Passos, Ives Cavalcante Kauer-Sant'Anna, Márcia Kapczinski, Flávio Pereira |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Boeira, Manuela Vianna Berni, Gabriela de Ávila Passos, Ives Cavalcante Kauer-Sant'Anna, Márcia Kapczinski, Flávio Pereira |
dc.subject.por.fl_str_mv |
Transtornos do humor Transtorno bipolar Estresse psicológico |
topic |
Transtornos do humor Transtorno bipolar Estresse psicológico Mood disorders Bipolar Suicide Stress Sexual assault Cognitive neuroscience |
dc.subject.eng.fl_str_mv |
Mood disorders Bipolar Suicide Stress Sexual assault Cognitive neuroscience |
description |
Family history and traumatic experiences are factors linked to bipolar disorder. It is known that the lifetime risk of bipolar disorder in relatives of a bipolar proband are 5-10% for first degree relatives and 40-70% for monozygotic co-twins. It is also known that patients with early childhood trauma present earlier onset of bipolar disorder, increased number of manic episodes, and more suicide attempts. We have recently reported that childhood trauma partly mediates the effect of family history on bipolar disorder diagnosis. In light of these findings from the scientific literature, we reviewed the work of British writer Virginia Woolf, who allegedly suffered from bipolar disorder. Her disorder was strongly related to her family background. Moreover, Virginia Woolf was sexually molested by her half siblings for nine years. Her bipolar disorder symptoms presented a pernicious course, associated with hospitalizations, suicidal behavioral, and functional impairment. The concept of neuroprogression has been used to explain the clinical deterioration that takes places in a subgroup of bipolar disorder patients. The examination of Virgina Woolf’s biography and art can provide clinicians with important insights about the course of bipolar disorder. |
publishDate |
2017 |
dc.date.accessioned.fl_str_mv |
2017-06-28T02:29:20Z |
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2017 |
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1516-4446 |
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Revista brasileira de psiquiatria (1999). São Paulo. Vol. 39, n. 1 (jan./mar. 2017), p. 69–71 |
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