Virginia Woolf, neuroprogression, and bipolar disorder

Detalhes bibliográficos
Autor(a) principal: Boeira, Manuela Vianna
Data de Publicação: 2017
Outros Autores: Berni, Gabriela de Ávila, Passos, Ives Cavalcante, Kauer-Sant'Anna, Márcia, Kapczinski, Flávio Pereira
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFRGS
Texto Completo: http://hdl.handle.net/10183/163556
Resumo: Family history and traumatic experiences are factors linked to bipolar disorder. It is known that the lifetime risk of bipolar disorder in relatives of a bipolar proband are 5-10% for first degree relatives and 40-70% for monozygotic co-twins. It is also known that patients with early childhood trauma present earlier onset of bipolar disorder, increased number of manic episodes, and more suicide attempts. We have recently reported that childhood trauma partly mediates the effect of family history on bipolar disorder diagnosis. In light of these findings from the scientific literature, we reviewed the work of British writer Virginia Woolf, who allegedly suffered from bipolar disorder. Her disorder was strongly related to her family background. Moreover, Virginia Woolf was sexually molested by her half siblings for nine years. Her bipolar disorder symptoms presented a pernicious course, associated with hospitalizations, suicidal behavioral, and functional impairment. The concept of neuroprogression has been used to explain the clinical deterioration that takes places in a subgroup of bipolar disorder patients. The examination of Virgina Woolf’s biography and art can provide clinicians with important insights about the course of bipolar disorder.
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spelling Boeira, Manuela ViannaBerni, Gabriela de ÁvilaPassos, Ives CavalcanteKauer-Sant'Anna, MárciaKapczinski, Flávio Pereira2017-06-28T02:29:20Z20171516-4446http://hdl.handle.net/10183/163556001017675Family history and traumatic experiences are factors linked to bipolar disorder. It is known that the lifetime risk of bipolar disorder in relatives of a bipolar proband are 5-10% for first degree relatives and 40-70% for monozygotic co-twins. It is also known that patients with early childhood trauma present earlier onset of bipolar disorder, increased number of manic episodes, and more suicide attempts. We have recently reported that childhood trauma partly mediates the effect of family history on bipolar disorder diagnosis. In light of these findings from the scientific literature, we reviewed the work of British writer Virginia Woolf, who allegedly suffered from bipolar disorder. Her disorder was strongly related to her family background. Moreover, Virginia Woolf was sexually molested by her half siblings for nine years. Her bipolar disorder symptoms presented a pernicious course, associated with hospitalizations, suicidal behavioral, and functional impairment. The concept of neuroprogression has been used to explain the clinical deterioration that takes places in a subgroup of bipolar disorder patients. The examination of Virgina Woolf’s biography and art can provide clinicians with important insights about the course of bipolar disorder.application/pdfengRevista brasileira de psiquiatria (1999). São Paulo. Vol. 39, n. 1 (jan./mar. 2017), p. 69–71Transtornos do humorTranstorno bipolarEstresse psicológicoMood disordersBipolarSuicideStressSexual assaultCognitive neuroscienceVirginia Woolf, neuroprogression, and bipolar disorderinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/otherinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL001017675.pdf001017675.pdfTexto completo (inglês)application/pdf59145http://www.lume.ufrgs.br/bitstream/10183/163556/1/001017675.pdf2fe184cf5c85b2e4d335d58420286b7bMD51TEXT001017675.pdf.txt001017675.pdf.txtExtracted Texttext/plain17966http://www.lume.ufrgs.br/bitstream/10183/163556/2/001017675.pdf.txt9955ac31e8769f06afeab22af3dc6a6eMD52THUMBNAIL001017675.pdf.jpg001017675.pdf.jpgGenerated Thumbnailimage/jpeg2031http://www.lume.ufrgs.br/bitstream/10183/163556/3/001017675.pdf.jpg0ac4f921bf6884ddaa86c4ef41629f38MD5310183/1635562022-09-23 04:41:44.307993oai:www.lume.ufrgs.br:10183/163556Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2022-09-23T07:41:44Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.pt_BR.fl_str_mv Virginia Woolf, neuroprogression, and bipolar disorder
title Virginia Woolf, neuroprogression, and bipolar disorder
spellingShingle Virginia Woolf, neuroprogression, and bipolar disorder
Boeira, Manuela Vianna
Transtornos do humor
Transtorno bipolar
Estresse psicológico
Mood disorders
Bipolar
Suicide
Stress
Sexual assault
Cognitive neuroscience
title_short Virginia Woolf, neuroprogression, and bipolar disorder
title_full Virginia Woolf, neuroprogression, and bipolar disorder
title_fullStr Virginia Woolf, neuroprogression, and bipolar disorder
title_full_unstemmed Virginia Woolf, neuroprogression, and bipolar disorder
title_sort Virginia Woolf, neuroprogression, and bipolar disorder
author Boeira, Manuela Vianna
author_facet Boeira, Manuela Vianna
Berni, Gabriela de Ávila
Passos, Ives Cavalcante
Kauer-Sant'Anna, Márcia
Kapczinski, Flávio Pereira
author_role author
author2 Berni, Gabriela de Ávila
Passos, Ives Cavalcante
Kauer-Sant'Anna, Márcia
Kapczinski, Flávio Pereira
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Boeira, Manuela Vianna
Berni, Gabriela de Ávila
Passos, Ives Cavalcante
Kauer-Sant'Anna, Márcia
Kapczinski, Flávio Pereira
dc.subject.por.fl_str_mv Transtornos do humor
Transtorno bipolar
Estresse psicológico
topic Transtornos do humor
Transtorno bipolar
Estresse psicológico
Mood disorders
Bipolar
Suicide
Stress
Sexual assault
Cognitive neuroscience
dc.subject.eng.fl_str_mv Mood disorders
Bipolar
Suicide
Stress
Sexual assault
Cognitive neuroscience
description Family history and traumatic experiences are factors linked to bipolar disorder. It is known that the lifetime risk of bipolar disorder in relatives of a bipolar proband are 5-10% for first degree relatives and 40-70% for monozygotic co-twins. It is also known that patients with early childhood trauma present earlier onset of bipolar disorder, increased number of manic episodes, and more suicide attempts. We have recently reported that childhood trauma partly mediates the effect of family history on bipolar disorder diagnosis. In light of these findings from the scientific literature, we reviewed the work of British writer Virginia Woolf, who allegedly suffered from bipolar disorder. Her disorder was strongly related to her family background. Moreover, Virginia Woolf was sexually molested by her half siblings for nine years. Her bipolar disorder symptoms presented a pernicious course, associated with hospitalizations, suicidal behavioral, and functional impairment. The concept of neuroprogression has been used to explain the clinical deterioration that takes places in a subgroup of bipolar disorder patients. The examination of Virgina Woolf’s biography and art can provide clinicians with important insights about the course of bipolar disorder.
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dc.relation.ispartof.pt_BR.fl_str_mv Revista brasileira de psiquiatria (1999). São Paulo. Vol. 39, n. 1 (jan./mar. 2017), p. 69–71
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