Changes in choroidal thickness and volume are related to urinary albumin excretion in type 2 diabetic patients without retinopathy

Detalhes bibliográficos
Autor(a) principal: Farias, Lucas Brandolt
Data de Publicação: 2018
Outros Autores: Lavinsky, Daniel, Benfica, Camila Zanella, Lavinsky, Jacó, Canani, Luis Henrique Santos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFRGS
Texto Completo: http://hdl.handle.net/10183/188875
Resumo: Purpose: To evaluate choroidal thickness and volume in patients with type 2 diabetes and microalbuminuria using spectral-domain optical coherence tomography. Methods: We recruited 37 diabetic patients without diabetic retinopathy (18 normoalbuminuric and 19 microalbuminuric) and 21 healthy controls. Choroidal thickness and volume were mapped using the automated Early Treatment Diabetic Retinopathy Study grid and a topographic map of thickness was generated manually. Choroid was also measured at 10 locations under the fovea, temporally and nasally. Results: Mean choroidal thickness and volume among patients with diabetes and microalbuminuria was reduced in all locations compared to controls (P,0.05). A sectoral decrease of choroidal thickness and volume was shown between microalbuminuric and normoalbuminuric groups. Conclusion: Choroidal changes were present in type 2 diabetic patients before clinical development of retinopathy. Microalbuminuria was associated with a decrease in choroidal thickness and volume in diabetic patients without diabetic retinopathy.
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spelling Farias, Lucas BrandoltLavinsky, DanielBenfica, Camila ZanellaLavinsky, JacóCanani, Luis Henrique Santos2019-02-20T02:36:28Z20181177-5483http://hdl.handle.net/10183/188875001085365Purpose: To evaluate choroidal thickness and volume in patients with type 2 diabetes and microalbuminuria using spectral-domain optical coherence tomography. Methods: We recruited 37 diabetic patients without diabetic retinopathy (18 normoalbuminuric and 19 microalbuminuric) and 21 healthy controls. Choroidal thickness and volume were mapped using the automated Early Treatment Diabetic Retinopathy Study grid and a topographic map of thickness was generated manually. Choroid was also measured at 10 locations under the fovea, temporally and nasally. Results: Mean choroidal thickness and volume among patients with diabetes and microalbuminuria was reduced in all locations compared to controls (P,0.05). A sectoral decrease of choroidal thickness and volume was shown between microalbuminuric and normoalbuminuric groups. Conclusion: Choroidal changes were present in type 2 diabetic patients before clinical development of retinopathy. Microalbuminuria was associated with a decrease in choroidal thickness and volume in diabetic patients without diabetic retinopathy.application/pdfengClinical ophthalmology [recurso eletrônico]. Auckland. vol. 12 (2018), p. 1405-1411CorioideDiabetes mellitus tipo 2MicroalbuminúriaChoroidal thicknessType 2 diabetesMicroalbuminuriaOptical coherence tomographyChanges in choroidal thickness and volume are related to urinary albumin excretion in type 2 diabetic patients without retinopathyEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001085365.pdf.txt001085365.pdf.txtExtracted Texttext/plain30852http://www.lume.ufrgs.br/bitstream/10183/188875/2/001085365.pdf.txtcbcc6e2d8e8414629715cb660fd287b9MD52ORIGINAL001085365.pdfTexto completo (inglês)application/pdf1510756http://www.lume.ufrgs.br/bitstream/10183/188875/1/001085365.pdf9ccaa42abbd43c9b90b5200d0c3f8159MD5110183/1888752019-02-21 02:34:36.351614oai:www.lume.ufrgs.br:10183/188875Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2019-02-21T05:34:36Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.pt_BR.fl_str_mv Changes in choroidal thickness and volume are related to urinary albumin excretion in type 2 diabetic patients without retinopathy
title Changes in choroidal thickness and volume are related to urinary albumin excretion in type 2 diabetic patients without retinopathy
spellingShingle Changes in choroidal thickness and volume are related to urinary albumin excretion in type 2 diabetic patients without retinopathy
Farias, Lucas Brandolt
Corioide
Diabetes mellitus tipo 2
Microalbuminúria
Choroidal thickness
Type 2 diabetes
Microalbuminuria
Optical coherence tomography
title_short Changes in choroidal thickness and volume are related to urinary albumin excretion in type 2 diabetic patients without retinopathy
title_full Changes in choroidal thickness and volume are related to urinary albumin excretion in type 2 diabetic patients without retinopathy
title_fullStr Changes in choroidal thickness and volume are related to urinary albumin excretion in type 2 diabetic patients without retinopathy
title_full_unstemmed Changes in choroidal thickness and volume are related to urinary albumin excretion in type 2 diabetic patients without retinopathy
title_sort Changes in choroidal thickness and volume are related to urinary albumin excretion in type 2 diabetic patients without retinopathy
author Farias, Lucas Brandolt
author_facet Farias, Lucas Brandolt
Lavinsky, Daniel
Benfica, Camila Zanella
Lavinsky, Jacó
Canani, Luis Henrique Santos
author_role author
author2 Lavinsky, Daniel
Benfica, Camila Zanella
Lavinsky, Jacó
Canani, Luis Henrique Santos
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Farias, Lucas Brandolt
Lavinsky, Daniel
Benfica, Camila Zanella
Lavinsky, Jacó
Canani, Luis Henrique Santos
dc.subject.por.fl_str_mv Corioide
Diabetes mellitus tipo 2
Microalbuminúria
topic Corioide
Diabetes mellitus tipo 2
Microalbuminúria
Choroidal thickness
Type 2 diabetes
Microalbuminuria
Optical coherence tomography
dc.subject.eng.fl_str_mv Choroidal thickness
Type 2 diabetes
Microalbuminuria
Optical coherence tomography
description Purpose: To evaluate choroidal thickness and volume in patients with type 2 diabetes and microalbuminuria using spectral-domain optical coherence tomography. Methods: We recruited 37 diabetic patients without diabetic retinopathy (18 normoalbuminuric and 19 microalbuminuric) and 21 healthy controls. Choroidal thickness and volume were mapped using the automated Early Treatment Diabetic Retinopathy Study grid and a topographic map of thickness was generated manually. Choroid was also measured at 10 locations under the fovea, temporally and nasally. Results: Mean choroidal thickness and volume among patients with diabetes and microalbuminuria was reduced in all locations compared to controls (P,0.05). A sectoral decrease of choroidal thickness and volume was shown between microalbuminuric and normoalbuminuric groups. Conclusion: Choroidal changes were present in type 2 diabetic patients before clinical development of retinopathy. Microalbuminuria was associated with a decrease in choroidal thickness and volume in diabetic patients without diabetic retinopathy.
publishDate 2018
dc.date.issued.fl_str_mv 2018
dc.date.accessioned.fl_str_mv 2019-02-20T02:36:28Z
dc.type.driver.fl_str_mv Estrangeiro
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dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10183/188875
dc.identifier.issn.pt_BR.fl_str_mv 1177-5483
dc.identifier.nrb.pt_BR.fl_str_mv 001085365
identifier_str_mv 1177-5483
001085365
url http://hdl.handle.net/10183/188875
dc.language.iso.fl_str_mv eng
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dc.relation.ispartof.pt_BR.fl_str_mv Clinical ophthalmology [recurso eletrônico]. Auckland. vol. 12 (2018), p. 1405-1411
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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reponame_str Repositório Institucional da UFRGS
collection Repositório Institucional da UFRGS
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