First case of degenerative mucinotic mural folliculitis in Brazil

• Autor(a) principal: Sousa Filho, Reginaldo Pereira de
• Data de Publicação: 2016
• Outros Autores: Rolim, Veronica Machado, Sampaio, Keytyanne de Oliveira, Driemeier, David, Cunha, Marina Gabriela Monteiro Carvalho Mori da, Costa, Fernanda Vieira Amorim da
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UFRGS
• Texto Completo: http://hdl.handle.net/10183/178587
• topic: Foliculite mural degenerativa mucinótica; Vírus da imunodeficiência felina; Diagnóstico; Tecnicas histologicas; Imuno-histoquímica; Brasil; Dermatology; Alopecia; Mucinosis; FIV; Chronic dermatitis

The purpose of this report is to describe the first case of degenerative mucinotic mural folliculitis (DMMF) in Brazil. This dermathopathy has been described as a rare cause of alopecia and hyperkeratosis in cats. Severe forms have been linked to infection with Feline Immunodeficiency Virus (FIV). A 10-year-old neutered male Siamese cat was referred with a 40 days history of progressive hair loss. The cat had initial alopecia on the head, subsequently spreading to the neck, torso and limbs. The skin biopsy revealed degenerative mucinotic mural folliculitis. Distinct seropositive reaction against FIV. antigens was demonstrated by enzyme-linked immunosorbent assay and immunohistochemistry. Therapeutic response to glucocorticoid medication, immunomodulators and antibiotics was poor and the patient died from undetermined causes. DMMF should be included in the differential diagnosis of feline exfoliative dermatitis and alopecia. Early diagnosis through histopathological and immunohistochemical tests is extremely important in determining the prognosis and the best treatment.