Biocompatibility of different intracanal medications in rat buccal submucosa tissue
Autor(a) principal: | |
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Data de Publicação: | 2008 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/61166 |
Resumo: | The aim of this study was to analyze the buccal tissue responses of Wistar rats to 2% chlorhexidine solution, calcium hydroxide and the association of both products. For this purpose, 30 specimens were randomly implanted in the filtrum of the four upper and lower hemiarches with a polyethylene tube containing one of the following substances: 2% chlorhexidine solution, calcium hydroxide and 2% chlorhexidine solution (test groups); calcium hydroxide and distilled water and distilled water (control groups). Ten rats each were distributed according to time interval of evaluation at 7, 15 and 30 days. The histological sections were stained with Harris hematoxylin and eosin. Analysis was performed with an optical microscope at x100, x200 and x400 magnifications by an expert examiner blinded to the materials. The sections were classified by scores attributed to inflammatory events and by a ranking determined according to the severity of the inflammation. The results of the inflammatory events and severity ranking were submitted to the Kruskal-Wallis test at a 0.05 level of significance. No statistically significant difference occurred among the tested materials; however, all materials showed a decreased of severity with respect to longer time intervals. |
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Semenoff, Tereza Aparecida Delle VedoveSegundo, Alex SemenoffFigueiredo, Jose Antonio Poli de2012-11-21T01:50:39Z20081678-7757http://hdl.handle.net/10183/61166000664867The aim of this study was to analyze the buccal tissue responses of Wistar rats to 2% chlorhexidine solution, calcium hydroxide and the association of both products. For this purpose, 30 specimens were randomly implanted in the filtrum of the four upper and lower hemiarches with a polyethylene tube containing one of the following substances: 2% chlorhexidine solution, calcium hydroxide and 2% chlorhexidine solution (test groups); calcium hydroxide and distilled water and distilled water (control groups). Ten rats each were distributed according to time interval of evaluation at 7, 15 and 30 days. The histological sections were stained with Harris hematoxylin and eosin. Analysis was performed with an optical microscope at x100, x200 and x400 magnifications by an expert examiner blinded to the materials. The sections were classified by scores attributed to inflammatory events and by a ranking determined according to the severity of the inflammation. The results of the inflammatory events and severity ranking were submitted to the Kruskal-Wallis test at a 0.05 level of significance. No statistically significant difference occurred among the tested materials; however, all materials showed a decreased of severity with respect to longer time intervals.application/pdfengJournal of applied oral science. Bauru. Vol. 16, no. 1 (Feb. 2008), p. 12-17Materiais biocompatíveisClorexidinaRatosEndodontiaBiocompatibilityCalcium hydroxideChlorhexidineEndodonticsRatsBiocompatibility of different intracanal medications in rat buccal submucosa tissueinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/otherinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL000664867.pdf000664867.pdfTexto completo (inglês)application/pdf206381http://www.lume.ufrgs.br/bitstream/10183/61166/1/000664867.pdf72817ff7d2e52fd1f3109c5a0abbe8f5MD51TEXT000664867.pdf.txt000664867.pdf.txtExtracted Texttext/plain27564http://www.lume.ufrgs.br/bitstream/10183/61166/2/000664867.pdf.txtaba074090ee361026c385fbcce043336MD52THUMBNAIL000664867.pdf.jpg000664867.pdf.jpgGenerated Thumbnailimage/jpeg1841http://www.lume.ufrgs.br/bitstream/10183/61166/3/000664867.pdf.jpg65933e9ad6c0610088a4c25206954f65MD5310183/611662023-08-11 03:51:33.956341oai:www.lume.ufrgs.br:10183/61166Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2023-08-11T06:51:33Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Biocompatibility of different intracanal medications in rat buccal submucosa tissue |
title |
Biocompatibility of different intracanal medications in rat buccal submucosa tissue |
spellingShingle |
Biocompatibility of different intracanal medications in rat buccal submucosa tissue Semenoff, Tereza Aparecida Delle Vedove Materiais biocompatíveis Clorexidina Ratos Endodontia Biocompatibility Calcium hydroxide Chlorhexidine Endodontics Rats |
title_short |
Biocompatibility of different intracanal medications in rat buccal submucosa tissue |
title_full |
Biocompatibility of different intracanal medications in rat buccal submucosa tissue |
title_fullStr |
Biocompatibility of different intracanal medications in rat buccal submucosa tissue |
title_full_unstemmed |
Biocompatibility of different intracanal medications in rat buccal submucosa tissue |
title_sort |
Biocompatibility of different intracanal medications in rat buccal submucosa tissue |
author |
Semenoff, Tereza Aparecida Delle Vedove |
author_facet |
Semenoff, Tereza Aparecida Delle Vedove Segundo, Alex Semenoff Figueiredo, Jose Antonio Poli de |
author_role |
author |
author2 |
Segundo, Alex Semenoff Figueiredo, Jose Antonio Poli de |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Semenoff, Tereza Aparecida Delle Vedove Segundo, Alex Semenoff Figueiredo, Jose Antonio Poli de |
dc.subject.por.fl_str_mv |
Materiais biocompatíveis Clorexidina Ratos Endodontia |
topic |
Materiais biocompatíveis Clorexidina Ratos Endodontia Biocompatibility Calcium hydroxide Chlorhexidine Endodontics Rats |
dc.subject.eng.fl_str_mv |
Biocompatibility Calcium hydroxide Chlorhexidine Endodontics Rats |
description |
The aim of this study was to analyze the buccal tissue responses of Wistar rats to 2% chlorhexidine solution, calcium hydroxide and the association of both products. For this purpose, 30 specimens were randomly implanted in the filtrum of the four upper and lower hemiarches with a polyethylene tube containing one of the following substances: 2% chlorhexidine solution, calcium hydroxide and 2% chlorhexidine solution (test groups); calcium hydroxide and distilled water and distilled water (control groups). Ten rats each were distributed according to time interval of evaluation at 7, 15 and 30 days. The histological sections were stained with Harris hematoxylin and eosin. Analysis was performed with an optical microscope at x100, x200 and x400 magnifications by an expert examiner blinded to the materials. The sections were classified by scores attributed to inflammatory events and by a ranking determined according to the severity of the inflammation. The results of the inflammatory events and severity ranking were submitted to the Kruskal-Wallis test at a 0.05 level of significance. No statistically significant difference occurred among the tested materials; however, all materials showed a decreased of severity with respect to longer time intervals. |
publishDate |
2008 |
dc.date.issued.fl_str_mv |
2008 |
dc.date.accessioned.fl_str_mv |
2012-11-21T01:50:39Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/other |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10183/61166 |
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1678-7757 |
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000664867 |
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1678-7757 000664867 |
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http://hdl.handle.net/10183/61166 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.pt_BR.fl_str_mv |
Journal of applied oral science. Bauru. Vol. 16, no. 1 (Feb. 2008), p. 12-17 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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