Efficacy of a triclosan formula in controlling early subgingival biofilm formation : a randomized trial
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/144248 |
Resumo: | Abstract: The aim of this study was to determine the efficacy of rinses with slurries of a dentifrice containing triclosan (TCS), as compared with rinses with slurries from a control dentifrice, in controlling early subgingival biofilm formation. A double-blind, randomized and cross-over clinical trial was designed, and 26 dental students were included. In the first period, participants were randomized to rinse with a TCS slurry or a control slurry, in a 12 h interval, and to refrain from mechanical cleaning. A Plaque Free Zone Index was assessed at 24 h, 48 h, 72 h and 96 h. After a washout period of 10 days, the second experimental period was conducted, following the same protocol as the first period, except that the slurry groups were switched. Use of the TCS slurry resulted in a significantly higher percentage of plaque-free surfaces, both at 24 h and at 72 h (p < 0.01). In the of 48-72 h interval, the triclosan slurry showed a lower percentage of sites converted to a score of 2 (38.1% for the test versus 40% for the control product, p = 0.015). In conclusion, rinsing with slurries of dentifrice containing TCS retards the down growth of bacterial biofilms from the supra- to the subgingival environment. |
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Andrade, ErnestoGomes, Sabrina CarvalhoWeidlich, PatríciaOppermann, Rui VicenteAngst, Patrícia Daniela Melchiors2016-08-05T02:15:07Z20151806-8324http://hdl.handle.net/10183/144248000980888Abstract: The aim of this study was to determine the efficacy of rinses with slurries of a dentifrice containing triclosan (TCS), as compared with rinses with slurries from a control dentifrice, in controlling early subgingival biofilm formation. A double-blind, randomized and cross-over clinical trial was designed, and 26 dental students were included. In the first period, participants were randomized to rinse with a TCS slurry or a control slurry, in a 12 h interval, and to refrain from mechanical cleaning. A Plaque Free Zone Index was assessed at 24 h, 48 h, 72 h and 96 h. After a washout period of 10 days, the second experimental period was conducted, following the same protocol as the first period, except that the slurry groups were switched. Use of the TCS slurry resulted in a significantly higher percentage of plaque-free surfaces, both at 24 h and at 72 h (p < 0.01). In the of 48-72 h interval, the triclosan slurry showed a lower percentage of sites converted to a score of 2 (38.1% for the test versus 40% for the control product, p = 0.015). In conclusion, rinsing with slurries of dentifrice containing TCS retards the down growth of bacterial biofilms from the supra- to the subgingival environment.application/pdfengBrazilian oral research. São Paulo. Vol. 29, no. 1 (2015), p. 1-8BiofilmesDoenças periodontaisBiofilmsGrowth and developmentTriclosanRandomized controlled trialEfficacy of a triclosan formula in controlling early subgingival biofilm formation : a randomized trialinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/otherinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL000980888.pdf000980888.pdfTexto completo (inglês)application/pdf347734http://www.lume.ufrgs.br/bitstream/10183/144248/1/000980888.pdf433f1fb2edd61b2596f19f26a15efc02MD51TEXT000980888.pdf.txt000980888.pdf.txtExtracted Texttext/plain27563http://www.lume.ufrgs.br/bitstream/10183/144248/2/000980888.pdf.txt379c5c02fce8d6bb6c3efed86d53fc6eMD52THUMBNAIL000980888.pdf.jpg000980888.pdf.jpgGenerated Thumbnailimage/jpeg1906http://www.lume.ufrgs.br/bitstream/10183/144248/3/000980888.pdf.jpgd3fe9a59b7ffb88403012ad88e57a5f4MD5310183/1442482018-10-29 07:47:13.41oai:www.lume.ufrgs.br:10183/144248Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2018-10-29T10:47:13Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Efficacy of a triclosan formula in controlling early subgingival biofilm formation : a randomized trial |
title |
Efficacy of a triclosan formula in controlling early subgingival biofilm formation : a randomized trial |
spellingShingle |
Efficacy of a triclosan formula in controlling early subgingival biofilm formation : a randomized trial Andrade, Ernesto Biofilmes Doenças periodontais Biofilms Growth and development Triclosan Randomized controlled trial |
title_short |
Efficacy of a triclosan formula in controlling early subgingival biofilm formation : a randomized trial |
title_full |
Efficacy of a triclosan formula in controlling early subgingival biofilm formation : a randomized trial |
title_fullStr |
Efficacy of a triclosan formula in controlling early subgingival biofilm formation : a randomized trial |
title_full_unstemmed |
Efficacy of a triclosan formula in controlling early subgingival biofilm formation : a randomized trial |
title_sort |
Efficacy of a triclosan formula in controlling early subgingival biofilm formation : a randomized trial |
author |
Andrade, Ernesto |
author_facet |
Andrade, Ernesto Gomes, Sabrina Carvalho Weidlich, Patrícia Oppermann, Rui Vicente Angst, Patrícia Daniela Melchiors |
author_role |
author |
author2 |
Gomes, Sabrina Carvalho Weidlich, Patrícia Oppermann, Rui Vicente Angst, Patrícia Daniela Melchiors |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Andrade, Ernesto Gomes, Sabrina Carvalho Weidlich, Patrícia Oppermann, Rui Vicente Angst, Patrícia Daniela Melchiors |
dc.subject.por.fl_str_mv |
Biofilmes Doenças periodontais |
topic |
Biofilmes Doenças periodontais Biofilms Growth and development Triclosan Randomized controlled trial |
dc.subject.eng.fl_str_mv |
Biofilms Growth and development Triclosan Randomized controlled trial |
description |
Abstract: The aim of this study was to determine the efficacy of rinses with slurries of a dentifrice containing triclosan (TCS), as compared with rinses with slurries from a control dentifrice, in controlling early subgingival biofilm formation. A double-blind, randomized and cross-over clinical trial was designed, and 26 dental students were included. In the first period, participants were randomized to rinse with a TCS slurry or a control slurry, in a 12 h interval, and to refrain from mechanical cleaning. A Plaque Free Zone Index was assessed at 24 h, 48 h, 72 h and 96 h. After a washout period of 10 days, the second experimental period was conducted, following the same protocol as the first period, except that the slurry groups were switched. Use of the TCS slurry resulted in a significantly higher percentage of plaque-free surfaces, both at 24 h and at 72 h (p < 0.01). In the of 48-72 h interval, the triclosan slurry showed a lower percentage of sites converted to a score of 2 (38.1% for the test versus 40% for the control product, p = 0.015). In conclusion, rinsing with slurries of dentifrice containing TCS retards the down growth of bacterial biofilms from the supra- to the subgingival environment. |
publishDate |
2015 |
dc.date.issued.fl_str_mv |
2015 |
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2016-08-05T02:15:07Z |
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eng |
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dc.relation.ispartof.pt_BR.fl_str_mv |
Brazilian oral research. São Paulo. Vol. 29, no. 1 (2015), p. 1-8 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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