Interaction between perceived maternal care, anxiety symptoms, and the neurobehavioral response to palatable foods in adolescents
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/206689 |
Resumo: | Studies in rodents have shown that early life trauma leads to anxiety, increased stress responses to threatening situations, and modifies food intake in a new environment. However, these associations are still to be tested in humans. This study aimed to verify complex interactions among anxiety diagnosis, maternal care, and baseline cortisol on food intake in a new environment in humans. A community sample of 32 adolescents and young adults was evaluated for: psychiatric diagnosis using standardized interviews, maternal care using the Parental Bonding Inventory (PBI), caloric consumption in a new environment (meal choice at a snack bar), and salivary cortisol. They also performed a brain fMRI task including the visualization of palatable foods vs. neutral items. The study found a three-way interaction between anxiety diagnosis, maternal care, and baseline cortisol levels on the total calories consumed (snacks) in a new environment. This interaction means that for those with high maternal care, there were no significant associations between cortisol levels and food intake in a new environment. However, for those with low maternal care and who have an anxiety disorder (affected), cortisol was associated with higher food intake; whereas for those with low maternal care and who did not have an anxiety disorder (resilient), cortisol was negatively associated with lower food intake. In addition, higher anxiety symptoms were associated with decreased activation in the superior and middle frontal gyrus when visualizing palatable vs. neutral items in those reporting high maternal care. These results in humans mimic experimental research findings and demonstrate that a combination of anxiety diagnosis and maternal care moderate the relationship between the HPA axis functioning, anxiety, and feeding behavior in adolescents and young adults. |
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Machado, Tania DinizDalle Molle, RobertaReis, Roberta SenaRodrigues, Danitsa MarcosMucellini, Amanda BrondaniMinuzzi, LucianoFranco, Alexandre RosaBuchweitz, AugustoToazza, RudineiaErgang, Bárbara CristinaCunha, Ana Carla de Araujo daSalum Junior, Giovanni AbrahãoManfro, Gisele GusSilveira, Patrícia Pelufo2020-03-12T04:13:42Z20161025-3890http://hdl.handle.net/10183/206689001014047Studies in rodents have shown that early life trauma leads to anxiety, increased stress responses to threatening situations, and modifies food intake in a new environment. However, these associations are still to be tested in humans. This study aimed to verify complex interactions among anxiety diagnosis, maternal care, and baseline cortisol on food intake in a new environment in humans. A community sample of 32 adolescents and young adults was evaluated for: psychiatric diagnosis using standardized interviews, maternal care using the Parental Bonding Inventory (PBI), caloric consumption in a new environment (meal choice at a snack bar), and salivary cortisol. They also performed a brain fMRI task including the visualization of palatable foods vs. neutral items. The study found a three-way interaction between anxiety diagnosis, maternal care, and baseline cortisol levels on the total calories consumed (snacks) in a new environment. This interaction means that for those with high maternal care, there were no significant associations between cortisol levels and food intake in a new environment. However, for those with low maternal care and who have an anxiety disorder (affected), cortisol was associated with higher food intake; whereas for those with low maternal care and who did not have an anxiety disorder (resilient), cortisol was negatively associated with lower food intake. In addition, higher anxiety symptoms were associated with decreased activation in the superior and middle frontal gyrus when visualizing palatable vs. neutral items in those reporting high maternal care. These results in humans mimic experimental research findings and demonstrate that a combination of anxiety diagnosis and maternal care moderate the relationship between the HPA axis functioning, anxiety, and feeding behavior in adolescents and young adults.application/pdfengStress. Amsterdam. Vol. 19, no. 3 (2016), p. 287-294AnsiedadeHidrocortisonaComportamento alimentarImagem por ressonância magnéticaObesidadeAnxietyCortisol;Feeding behaviorFunctional fMRIObesityPoor maternal careInteraction between perceived maternal care, anxiety symptoms, and the neurobehavioral response to palatable foods in adolescentsEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001014047.pdf.txt001014047.pdf.txtExtracted Texttext/plain48439http://www.lume.ufrgs.br/bitstream/10183/206689/2/001014047.pdf.txt58b3df51acdf01bf8b513266fbad892eMD52ORIGINAL001014047.pdfTexto completo (inglês)application/pdf1167519http://www.lume.ufrgs.br/bitstream/10183/206689/1/001014047.pdf09db7f55357403c0070b3cb36884f291MD5110183/2066892020-03-13 04:16:26.033617oai:www.lume.ufrgs.br:10183/206689Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2020-03-13T07:16:26Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Interaction between perceived maternal care, anxiety symptoms, and the neurobehavioral response to palatable foods in adolescents |
title |
Interaction between perceived maternal care, anxiety symptoms, and the neurobehavioral response to palatable foods in adolescents |
spellingShingle |
Interaction between perceived maternal care, anxiety symptoms, and the neurobehavioral response to palatable foods in adolescents Machado, Tania Diniz Ansiedade Hidrocortisona Comportamento alimentar Imagem por ressonância magnética Obesidade Anxiety Cortisol; Feeding behavior Functional fMRI Obesity Poor maternal care |
title_short |
Interaction between perceived maternal care, anxiety symptoms, and the neurobehavioral response to palatable foods in adolescents |
title_full |
Interaction between perceived maternal care, anxiety symptoms, and the neurobehavioral response to palatable foods in adolescents |
title_fullStr |
Interaction between perceived maternal care, anxiety symptoms, and the neurobehavioral response to palatable foods in adolescents |
title_full_unstemmed |
Interaction between perceived maternal care, anxiety symptoms, and the neurobehavioral response to palatable foods in adolescents |
title_sort |
Interaction between perceived maternal care, anxiety symptoms, and the neurobehavioral response to palatable foods in adolescents |
author |
Machado, Tania Diniz |
author_facet |
Machado, Tania Diniz Dalle Molle, Roberta Reis, Roberta Sena Rodrigues, Danitsa Marcos Mucellini, Amanda Brondani Minuzzi, Luciano Franco, Alexandre Rosa Buchweitz, Augusto Toazza, Rudineia Ergang, Bárbara Cristina Cunha, Ana Carla de Araujo da Salum Junior, Giovanni Abrahão Manfro, Gisele Gus Silveira, Patrícia Pelufo |
author_role |
author |
author2 |
Dalle Molle, Roberta Reis, Roberta Sena Rodrigues, Danitsa Marcos Mucellini, Amanda Brondani Minuzzi, Luciano Franco, Alexandre Rosa Buchweitz, Augusto Toazza, Rudineia Ergang, Bárbara Cristina Cunha, Ana Carla de Araujo da Salum Junior, Giovanni Abrahão Manfro, Gisele Gus Silveira, Patrícia Pelufo |
author2_role |
author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Machado, Tania Diniz Dalle Molle, Roberta Reis, Roberta Sena Rodrigues, Danitsa Marcos Mucellini, Amanda Brondani Minuzzi, Luciano Franco, Alexandre Rosa Buchweitz, Augusto Toazza, Rudineia Ergang, Bárbara Cristina Cunha, Ana Carla de Araujo da Salum Junior, Giovanni Abrahão Manfro, Gisele Gus Silveira, Patrícia Pelufo |
dc.subject.por.fl_str_mv |
Ansiedade Hidrocortisona Comportamento alimentar Imagem por ressonância magnética Obesidade |
topic |
Ansiedade Hidrocortisona Comportamento alimentar Imagem por ressonância magnética Obesidade Anxiety Cortisol; Feeding behavior Functional fMRI Obesity Poor maternal care |
dc.subject.eng.fl_str_mv |
Anxiety Cortisol; Feeding behavior Functional fMRI Obesity Poor maternal care |
description |
Studies in rodents have shown that early life trauma leads to anxiety, increased stress responses to threatening situations, and modifies food intake in a new environment. However, these associations are still to be tested in humans. This study aimed to verify complex interactions among anxiety diagnosis, maternal care, and baseline cortisol on food intake in a new environment in humans. A community sample of 32 adolescents and young adults was evaluated for: psychiatric diagnosis using standardized interviews, maternal care using the Parental Bonding Inventory (PBI), caloric consumption in a new environment (meal choice at a snack bar), and salivary cortisol. They also performed a brain fMRI task including the visualization of palatable foods vs. neutral items. The study found a three-way interaction between anxiety diagnosis, maternal care, and baseline cortisol levels on the total calories consumed (snacks) in a new environment. This interaction means that for those with high maternal care, there were no significant associations between cortisol levels and food intake in a new environment. However, for those with low maternal care and who have an anxiety disorder (affected), cortisol was associated with higher food intake; whereas for those with low maternal care and who did not have an anxiety disorder (resilient), cortisol was negatively associated with lower food intake. In addition, higher anxiety symptoms were associated with decreased activation in the superior and middle frontal gyrus when visualizing palatable vs. neutral items in those reporting high maternal care. These results in humans mimic experimental research findings and demonstrate that a combination of anxiety diagnosis and maternal care moderate the relationship between the HPA axis functioning, anxiety, and feeding behavior in adolescents and young adults. |
publishDate |
2016 |
dc.date.issued.fl_str_mv |
2016 |
dc.date.accessioned.fl_str_mv |
2020-03-12T04:13:42Z |
dc.type.driver.fl_str_mv |
Estrangeiro info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10183/206689 |
dc.identifier.issn.pt_BR.fl_str_mv |
1025-3890 |
dc.identifier.nrb.pt_BR.fl_str_mv |
001014047 |
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1025-3890 001014047 |
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http://hdl.handle.net/10183/206689 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.pt_BR.fl_str_mv |
Stress. Amsterdam. Vol. 19, no. 3 (2016), p. 287-294 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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