Aryl-hydrocarbon receptor binding and the incidence of type 2 diabetes : the brazilian longitudinal study of adult health (ELSABrasil)

Detalhes bibliográficos
Autor(a) principal: Duncan, Bruce Bartholow
Data de Publicação: 2020
Outros Autores: Castilhos, Cristina D., Bracco, Paula Andreghetto, Schmidt, Maria Inês, Sora, Kang, Suyeol, Im, Hong, Kyu Lee, Vigo, Álvaro, Youngmi, Kim Pak
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFRGS
Texto Completo: http://hdl.handle.net/10183/223073
Resumo: Persistent organic pollutants (POPs) may cause diabetes, in part through aryl hydrocarbon receptor (AhR) binding. Ensuing mitochondrial dysfunction is postulated to mediate this effect. We aim to investigate the association of POPs with incident diabetes indirectly by bio-assaying AhR ligand bioactivity and intracellular ATP level induced by participant serum samples.
id UFRGS-2_77bd194a5d798718fd3ab9ee646aad3a
oai_identifier_str oai:www.lume.ufrgs.br:10183/223073
network_acronym_str UFRGS-2
network_name_str Repositório Institucional da UFRGS
repository_id_str
spelling Duncan, Bruce BartholowCastilhos, Cristina D.Bracco, Paula AndreghettoSchmidt, Maria InêsSora, KangSuyeol, ImHong, Kyu LeeVigo, ÁlvaroYoungmi, Kim Pak2021-07-01T04:29:35Z20201476-069Xhttp://hdl.handle.net/10183/223073001120278Persistent organic pollutants (POPs) may cause diabetes, in part through aryl hydrocarbon receptor (AhR) binding. Ensuing mitochondrial dysfunction is postulated to mediate this effect. We aim to investigate the association of POPs with incident diabetes indirectly by bio-assaying AhR ligand bioactivity and intracellular ATP level induced by participant serum samples.application/pdfengEnvironmental Health. BioMed Central. Vol. 19, (2020), 105, p. 1 - 8.Diabetes mellitusPoluentes orgânicosAryl-hydrocarbon receptor binding and the incidence of type 2 diabetes : the brazilian longitudinal study of adult health (ELSABrasil)Estrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001120278.pdf.txt001120278.pdf.txtExtracted Texttext/plain37742http://www.lume.ufrgs.br/bitstream/10183/223073/2/001120278.pdf.txt7b1aaba73410154d7e2a1299732605b8MD52ORIGINAL001120278.pdfTexto completo (inglês)application/pdf692570http://www.lume.ufrgs.br/bitstream/10183/223073/1/001120278.pdfafead9a5ac53acc3b91b01cfa0681af2MD5110183/2230732023-10-22 03:38:30.79969oai:www.lume.ufrgs.br:10183/223073Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2023-10-22T06:38:30Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.pt_BR.fl_str_mv Aryl-hydrocarbon receptor binding and the incidence of type 2 diabetes : the brazilian longitudinal study of adult health (ELSABrasil)
title Aryl-hydrocarbon receptor binding and the incidence of type 2 diabetes : the brazilian longitudinal study of adult health (ELSABrasil)
spellingShingle Aryl-hydrocarbon receptor binding and the incidence of type 2 diabetes : the brazilian longitudinal study of adult health (ELSABrasil)
Duncan, Bruce Bartholow
Diabetes mellitus
Poluentes orgânicos
title_short Aryl-hydrocarbon receptor binding and the incidence of type 2 diabetes : the brazilian longitudinal study of adult health (ELSABrasil)
title_full Aryl-hydrocarbon receptor binding and the incidence of type 2 diabetes : the brazilian longitudinal study of adult health (ELSABrasil)
title_fullStr Aryl-hydrocarbon receptor binding and the incidence of type 2 diabetes : the brazilian longitudinal study of adult health (ELSABrasil)
title_full_unstemmed Aryl-hydrocarbon receptor binding and the incidence of type 2 diabetes : the brazilian longitudinal study of adult health (ELSABrasil)
title_sort Aryl-hydrocarbon receptor binding and the incidence of type 2 diabetes : the brazilian longitudinal study of adult health (ELSABrasil)
author Duncan, Bruce Bartholow
author_facet Duncan, Bruce Bartholow
Castilhos, Cristina D.
Bracco, Paula Andreghetto
Schmidt, Maria Inês
Sora, Kang
Suyeol, Im
Hong, Kyu Lee
Vigo, Álvaro
Youngmi, Kim Pak
author_role author
author2 Castilhos, Cristina D.
Bracco, Paula Andreghetto
Schmidt, Maria Inês
Sora, Kang
Suyeol, Im
Hong, Kyu Lee
Vigo, Álvaro
Youngmi, Kim Pak
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Duncan, Bruce Bartholow
Castilhos, Cristina D.
Bracco, Paula Andreghetto
Schmidt, Maria Inês
Sora, Kang
Suyeol, Im
Hong, Kyu Lee
Vigo, Álvaro
Youngmi, Kim Pak
dc.subject.por.fl_str_mv Diabetes mellitus
Poluentes orgânicos
topic Diabetes mellitus
Poluentes orgânicos
description Persistent organic pollutants (POPs) may cause diabetes, in part through aryl hydrocarbon receptor (AhR) binding. Ensuing mitochondrial dysfunction is postulated to mediate this effect. We aim to investigate the association of POPs with incident diabetes indirectly by bio-assaying AhR ligand bioactivity and intracellular ATP level induced by participant serum samples.
publishDate 2020
dc.date.issued.fl_str_mv 2020
dc.date.accessioned.fl_str_mv 2021-07-01T04:29:35Z
dc.type.driver.fl_str_mv Estrangeiro
info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10183/223073
dc.identifier.issn.pt_BR.fl_str_mv 1476-069X
dc.identifier.nrb.pt_BR.fl_str_mv 001120278
identifier_str_mv 1476-069X
001120278
url http://hdl.handle.net/10183/223073
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.pt_BR.fl_str_mv Environmental Health. BioMed Central. Vol. 19, (2020), 105, p. 1 - 8.
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFRGS
instname:Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
instname_str Universidade Federal do Rio Grande do Sul (UFRGS)
instacron_str UFRGS
institution UFRGS
reponame_str Repositório Institucional da UFRGS
collection Repositório Institucional da UFRGS
bitstream.url.fl_str_mv http://www.lume.ufrgs.br/bitstream/10183/223073/2/001120278.pdf.txt
http://www.lume.ufrgs.br/bitstream/10183/223073/1/001120278.pdf
bitstream.checksum.fl_str_mv 7b1aaba73410154d7e2a1299732605b8
afead9a5ac53acc3b91b01cfa0681af2
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
repository.name.fl_str_mv Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)
repository.mail.fl_str_mv
_version_ 1815447748096294912

Registros relacionados