How early life stress impact maternal care : a systematic review of rodent studies
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/216372 |
Resumo: | Background: Maternal care refers to the behavior performed by the dam to nourish and protect her litter during its early development. Frequent and high-quality performance of such maternal behaviors is critical for the neurodevelopment of the pups. Maternal exposure to stress during early development can impair maternal care and amplify the deleterious effects of poor maternal caregiving and neglect. As such, a thorough understanding of the effects caused by several models of early life stress on maternal care may yield more insights into the relationship between stress and maternal behavior. Methods: A systematic review was performed to identify and address the effects of early life stress on maternal behavior. The search was conducted using three online databases: PUBMED, Embase, and Web of Science. To provide clear evidence of the impact of stress on maternal care, in every study, the stress group was always compared to a control group. Outcomes were categorized into eight different behaviors: (1) licking/grooming; (2) arched-back nursing; (3) blanket-nursing/passive nursing; (4) nest building; (5) contact with pups; (6) harmful/adverse caregiving; (7) no contact; (8) nest exits. Additionally, the methodological quality of the studies was evaluated. Results: A total of 12 different early life stress protocols were identified from the 56 studies included in this systematic review. Our data demonstrate that different stress models can promote specific maternal patterns of behavior. Regarding the maternal separation protocol, we observed an overall increase in nursing and licking/grooming behaviors, which are essential for pup development. An increase in the number of nest exits, which represents a fragmentation of maternal care, was observed in the limited bedding protocol, but the total amount of maternal care appears to remain similar between groups. Conclusions: Each stress protocol has unique characteristics that increase the difficulty of rendering comparisons of maternal behavior. The increase in maternal care observed in the maternal separation protocol may be an attempt to overcompensate for the time off-nest. Fragmented maternal care is a key component of the limited bedding protocol. Moreover, the methodological approaches to evaluate maternal behavior, such as time, duration, and behavior type should be more homogeneous across studies. |
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Orso, RodrigoCreutzberg, Kerstin CamileSilva, Luis Eduardo Wearick daViola, Thiago WendtTractenberg, Saulo GantesBenetti, FernandoGrassi-Oliveira, Rodrigo2020-12-11T04:11:37Z20191662-5153http://hdl.handle.net/10183/216372001119254Background: Maternal care refers to the behavior performed by the dam to nourish and protect her litter during its early development. Frequent and high-quality performance of such maternal behaviors is critical for the neurodevelopment of the pups. Maternal exposure to stress during early development can impair maternal care and amplify the deleterious effects of poor maternal caregiving and neglect. As such, a thorough understanding of the effects caused by several models of early life stress on maternal care may yield more insights into the relationship between stress and maternal behavior. Methods: A systematic review was performed to identify and address the effects of early life stress on maternal behavior. The search was conducted using three online databases: PUBMED, Embase, and Web of Science. To provide clear evidence of the impact of stress on maternal care, in every study, the stress group was always compared to a control group. Outcomes were categorized into eight different behaviors: (1) licking/grooming; (2) arched-back nursing; (3) blanket-nursing/passive nursing; (4) nest building; (5) contact with pups; (6) harmful/adverse caregiving; (7) no contact; (8) nest exits. Additionally, the methodological quality of the studies was evaluated. Results: A total of 12 different early life stress protocols were identified from the 56 studies included in this systematic review. Our data demonstrate that different stress models can promote specific maternal patterns of behavior. Regarding the maternal separation protocol, we observed an overall increase in nursing and licking/grooming behaviors, which are essential for pup development. An increase in the number of nest exits, which represents a fragmentation of maternal care, was observed in the limited bedding protocol, but the total amount of maternal care appears to remain similar between groups. Conclusions: Each stress protocol has unique characteristics that increase the difficulty of rendering comparisons of maternal behavior. The increase in maternal care observed in the maternal separation protocol may be an attempt to overcompensate for the time off-nest. Fragmented maternal care is a key component of the limited bedding protocol. Moreover, the methodological approaches to evaluate maternal behavior, such as time, duration, and behavior type should be more homogeneous across studies.application/pdfengFrontiers in behavioral neuroscience. Lausanne. Vol.13 (Aug. 2019), 197, 17 p.Comportamento maternoEstresse fisiológicoRecém-nascidoEarly life stressMaternal careMaternal behaviorRodentSystematic reviewPostnatal stressHow early life stress impact maternal care : a systematic review of rodent studiesEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001119254.pdf.txt001119254.pdf.txtExtracted Texttext/plain84948http://www.lume.ufrgs.br/bitstream/10183/216372/2/001119254.pdf.txte07bf8dfdc8ec23758f5c4f5b67770e1MD52ORIGINAL001119254.pdfTexto completo (inglês)application/pdf3068739http://www.lume.ufrgs.br/bitstream/10183/216372/1/001119254.pdf5a0e59d04ec2032d8ae68f6b6df2e6d6MD5110183/2163722020-12-12 05:19:56.714803oai:www.lume.ufrgs.br:10183/216372Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2020-12-12T07:19:56Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
How early life stress impact maternal care : a systematic review of rodent studies |
title |
How early life stress impact maternal care : a systematic review of rodent studies |
spellingShingle |
How early life stress impact maternal care : a systematic review of rodent studies Orso, Rodrigo Comportamento materno Estresse fisiológico Recém-nascido Early life stress Maternal care Maternal behavior Rodent Systematic review Postnatal stress |
title_short |
How early life stress impact maternal care : a systematic review of rodent studies |
title_full |
How early life stress impact maternal care : a systematic review of rodent studies |
title_fullStr |
How early life stress impact maternal care : a systematic review of rodent studies |
title_full_unstemmed |
How early life stress impact maternal care : a systematic review of rodent studies |
title_sort |
How early life stress impact maternal care : a systematic review of rodent studies |
author |
Orso, Rodrigo |
author_facet |
Orso, Rodrigo Creutzberg, Kerstin Camile Silva, Luis Eduardo Wearick da Viola, Thiago Wendt Tractenberg, Saulo Gantes Benetti, Fernando Grassi-Oliveira, Rodrigo |
author_role |
author |
author2 |
Creutzberg, Kerstin Camile Silva, Luis Eduardo Wearick da Viola, Thiago Wendt Tractenberg, Saulo Gantes Benetti, Fernando Grassi-Oliveira, Rodrigo |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Orso, Rodrigo Creutzberg, Kerstin Camile Silva, Luis Eduardo Wearick da Viola, Thiago Wendt Tractenberg, Saulo Gantes Benetti, Fernando Grassi-Oliveira, Rodrigo |
dc.subject.por.fl_str_mv |
Comportamento materno Estresse fisiológico Recém-nascido |
topic |
Comportamento materno Estresse fisiológico Recém-nascido Early life stress Maternal care Maternal behavior Rodent Systematic review Postnatal stress |
dc.subject.eng.fl_str_mv |
Early life stress Maternal care Maternal behavior Rodent Systematic review Postnatal stress |
description |
Background: Maternal care refers to the behavior performed by the dam to nourish and protect her litter during its early development. Frequent and high-quality performance of such maternal behaviors is critical for the neurodevelopment of the pups. Maternal exposure to stress during early development can impair maternal care and amplify the deleterious effects of poor maternal caregiving and neglect. As such, a thorough understanding of the effects caused by several models of early life stress on maternal care may yield more insights into the relationship between stress and maternal behavior. Methods: A systematic review was performed to identify and address the effects of early life stress on maternal behavior. The search was conducted using three online databases: PUBMED, Embase, and Web of Science. To provide clear evidence of the impact of stress on maternal care, in every study, the stress group was always compared to a control group. Outcomes were categorized into eight different behaviors: (1) licking/grooming; (2) arched-back nursing; (3) blanket-nursing/passive nursing; (4) nest building; (5) contact with pups; (6) harmful/adverse caregiving; (7) no contact; (8) nest exits. Additionally, the methodological quality of the studies was evaluated. Results: A total of 12 different early life stress protocols were identified from the 56 studies included in this systematic review. Our data demonstrate that different stress models can promote specific maternal patterns of behavior. Regarding the maternal separation protocol, we observed an overall increase in nursing and licking/grooming behaviors, which are essential for pup development. An increase in the number of nest exits, which represents a fragmentation of maternal care, was observed in the limited bedding protocol, but the total amount of maternal care appears to remain similar between groups. Conclusions: Each stress protocol has unique characteristics that increase the difficulty of rendering comparisons of maternal behavior. The increase in maternal care observed in the maternal separation protocol may be an attempt to overcompensate for the time off-nest. Fragmented maternal care is a key component of the limited bedding protocol. Moreover, the methodological approaches to evaluate maternal behavior, such as time, duration, and behavior type should be more homogeneous across studies. |
publishDate |
2019 |
dc.date.issued.fl_str_mv |
2019 |
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2020-12-11T04:11:37Z |
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http://hdl.handle.net/10183/216372 |
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001119254 |
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dc.relation.ispartof.pt_BR.fl_str_mv |
Frontiers in behavioral neuroscience. Lausanne. Vol.13 (Aug. 2019), 197, 17 p. |
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