Cardiovascular disease risk in women with migraine
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/111806 |
Resumo: | Background: Studies suggest a higher prevalence of unfavourable cardiovascular risk factors amongst migraineurs, but results have been conflicting. The aim of this study was to investigate traditional and newly recognized risk factors as well as other surrogate markers of cardiovascular risk in obese and normal weight women with migraine. Methods: Fifty-nine adult female probands participated in this case–control study. The sample was divided into normal weight and obese migraineurs and age- and body mass index-matched control groups. The following cardiovascular risk factors were analyzed: serum levels of lipids, fasting glucose, and insulin; insulin resistance; blood pressure; smoking (categorized as current, past or never); Framingham 10-year risk of general cardiovascular disease score; C-reactive protein; family history of cardiovascular disease; physical activity; sleep disturbances; depression; and bioelectrical impedance phase angle. The means of continuous variables were compared using Student’s t-test for independent samples or the Mann–Whitney U-test (for 2 groups) and ANOVA or the Kruskal-Wallis test (for 4 groups) depending on the distribution of data. Results: All migraineurs were sedentary irrespective of nutritional status. Migraineurs had higher depression scores and shorter sleep duration, and obese migraineurs, in particular, had worse sleep quality scores. Insulin resistance and insulinaemia were associated with obesity, and obese migraineurs had lower HDL-c than normal weight controls and migraineurs. Also, the Framingham risk score was higher in obese migraineurs. Conclusion: These findings suggest that female migraineurs experience marked inactivity, depression, and some sleep disturbance, that higher insulin resistance and insulinaemia are related to obesity, and that obesity and migraine probably exert overlapping effects on HDL-c levels and Framingham 10-year cardiovascular risk. |
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Rockett, Fernanda CamboimPerla, Alexandre da SilveiraPerry, Ingrid Dalira SchweigertChaves, Marcia Lorena Fagundes2015-03-07T01:56:56Z20131129-2369http://hdl.handle.net/10183/111806000952892Background: Studies suggest a higher prevalence of unfavourable cardiovascular risk factors amongst migraineurs, but results have been conflicting. The aim of this study was to investigate traditional and newly recognized risk factors as well as other surrogate markers of cardiovascular risk in obese and normal weight women with migraine. Methods: Fifty-nine adult female probands participated in this case–control study. The sample was divided into normal weight and obese migraineurs and age- and body mass index-matched control groups. The following cardiovascular risk factors were analyzed: serum levels of lipids, fasting glucose, and insulin; insulin resistance; blood pressure; smoking (categorized as current, past or never); Framingham 10-year risk of general cardiovascular disease score; C-reactive protein; family history of cardiovascular disease; physical activity; sleep disturbances; depression; and bioelectrical impedance phase angle. The means of continuous variables were compared using Student’s t-test for independent samples or the Mann–Whitney U-test (for 2 groups) and ANOVA or the Kruskal-Wallis test (for 4 groups) depending on the distribution of data. Results: All migraineurs were sedentary irrespective of nutritional status. Migraineurs had higher depression scores and shorter sleep duration, and obese migraineurs, in particular, had worse sleep quality scores. Insulin resistance and insulinaemia were associated with obesity, and obese migraineurs had lower HDL-c than normal weight controls and migraineurs. Also, the Framingham risk score was higher in obese migraineurs. Conclusion: These findings suggest that female migraineurs experience marked inactivity, depression, and some sleep disturbance, that higher insulin resistance and insulinaemia are related to obesity, and that obesity and migraine probably exert overlapping effects on HDL-c levels and Framingham 10-year cardiovascular risk.application/pdfengJournal of headache and pain. Milano. Vol. 14, (Dec. 2013), 75, 9 p.Transtornos de enxaquecaDoenças cardiovascularesFatores de riscoProteina C-reativaDepressãoTranstornos do sono-vigíliaMigraineCardiovascular diseaseCardiovascular riskC-reactive proteinDepressionSleep disturbanceCardiovascular disease risk in women with migraineEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL000952892.pdf000952892.pdfTexto completo (inglês)application/pdf214002http://www.lume.ufrgs.br/bitstream/10183/111806/1/000952892.pdfdba030ef433247402b0dd659c44a9df3MD51TEXT000952892.pdf.txt000952892.pdf.txtExtracted Texttext/plain48323http://www.lume.ufrgs.br/bitstream/10183/111806/2/000952892.pdf.txt68b509cea255bf88ff7c9b30139b585aMD52THUMBNAIL000952892.pdf.jpg000952892.pdf.jpgGenerated Thumbnailimage/jpeg1894http://www.lume.ufrgs.br/bitstream/10183/111806/3/000952892.pdf.jpgb6d4ec0d61df3eaa15a2f34caff1329aMD5310183/1118062023-10-01 03:37:19.886563oai:www.lume.ufrgs.br:10183/111806Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2023-10-01T06:37:19Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Cardiovascular disease risk in women with migraine |
title |
Cardiovascular disease risk in women with migraine |
spellingShingle |
Cardiovascular disease risk in women with migraine Rockett, Fernanda Camboim Transtornos de enxaqueca Doenças cardiovasculares Fatores de risco Proteina C-reativa Depressão Transtornos do sono-vigília Migraine Cardiovascular disease Cardiovascular risk C-reactive protein Depression Sleep disturbance |
title_short |
Cardiovascular disease risk in women with migraine |
title_full |
Cardiovascular disease risk in women with migraine |
title_fullStr |
Cardiovascular disease risk in women with migraine |
title_full_unstemmed |
Cardiovascular disease risk in women with migraine |
title_sort |
Cardiovascular disease risk in women with migraine |
author |
Rockett, Fernanda Camboim |
author_facet |
Rockett, Fernanda Camboim Perla, Alexandre da Silveira Perry, Ingrid Dalira Schweigert Chaves, Marcia Lorena Fagundes |
author_role |
author |
author2 |
Perla, Alexandre da Silveira Perry, Ingrid Dalira Schweigert Chaves, Marcia Lorena Fagundes |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Rockett, Fernanda Camboim Perla, Alexandre da Silveira Perry, Ingrid Dalira Schweigert Chaves, Marcia Lorena Fagundes |
dc.subject.por.fl_str_mv |
Transtornos de enxaqueca Doenças cardiovasculares Fatores de risco Proteina C-reativa Depressão Transtornos do sono-vigília |
topic |
Transtornos de enxaqueca Doenças cardiovasculares Fatores de risco Proteina C-reativa Depressão Transtornos do sono-vigília Migraine Cardiovascular disease Cardiovascular risk C-reactive protein Depression Sleep disturbance |
dc.subject.eng.fl_str_mv |
Migraine Cardiovascular disease Cardiovascular risk C-reactive protein Depression Sleep disturbance |
description |
Background: Studies suggest a higher prevalence of unfavourable cardiovascular risk factors amongst migraineurs, but results have been conflicting. The aim of this study was to investigate traditional and newly recognized risk factors as well as other surrogate markers of cardiovascular risk in obese and normal weight women with migraine. Methods: Fifty-nine adult female probands participated in this case–control study. The sample was divided into normal weight and obese migraineurs and age- and body mass index-matched control groups. The following cardiovascular risk factors were analyzed: serum levels of lipids, fasting glucose, and insulin; insulin resistance; blood pressure; smoking (categorized as current, past or never); Framingham 10-year risk of general cardiovascular disease score; C-reactive protein; family history of cardiovascular disease; physical activity; sleep disturbances; depression; and bioelectrical impedance phase angle. The means of continuous variables were compared using Student’s t-test for independent samples or the Mann–Whitney U-test (for 2 groups) and ANOVA or the Kruskal-Wallis test (for 4 groups) depending on the distribution of data. Results: All migraineurs were sedentary irrespective of nutritional status. Migraineurs had higher depression scores and shorter sleep duration, and obese migraineurs, in particular, had worse sleep quality scores. Insulin resistance and insulinaemia were associated with obesity, and obese migraineurs had lower HDL-c than normal weight controls and migraineurs. Also, the Framingham risk score was higher in obese migraineurs. Conclusion: These findings suggest that female migraineurs experience marked inactivity, depression, and some sleep disturbance, that higher insulin resistance and insulinaemia are related to obesity, and that obesity and migraine probably exert overlapping effects on HDL-c levels and Framingham 10-year cardiovascular risk. |
publishDate |
2013 |
dc.date.issued.fl_str_mv |
2013 |
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2015-03-07T01:56:56Z |
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http://hdl.handle.net/10183/111806 |
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1129-2369 |
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000952892 |
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http://hdl.handle.net/10183/111806 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.pt_BR.fl_str_mv |
Journal of headache and pain. Milano. Vol. 14, (Dec. 2013), 75, 9 p. |
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openAccess |
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