Two cases of neural tube defects with dolutegravir use at conception in south Brazil

Detalhes bibliográficos
Autor(a) principal: Kreitchmann, Regis
Data de Publicação: 2021
Outros Autores: Oliveira, Fernando Rocha de, Sprinz, Eduardo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFRGS
Texto Completo: http://hdl.handle.net/10183/236731
Resumo: Dolutegravir (DTG) is amongst the most prescribed antiretrovirals worldwide and is recommended as first line regimen in most HIV treatment guidelines. Its use, although infrequently, had been associated to an increased chance of neural tube defects (NTD) in Botswana, Africa. Herein we describe two cases of NTD in women who conceived while taking DTG as part of their antiretroviral treatment in the city of Porto Alegre, Brazil.
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spelling Kreitchmann, RegisOliveira, Fernando Rocha deSprinz, Eduardo2022-04-07T04:48:29Z20211413-8670http://hdl.handle.net/10183/236731001137454Dolutegravir (DTG) is amongst the most prescribed antiretrovirals worldwide and is recommended as first line regimen in most HIV treatment guidelines. Its use, although infrequently, had been associated to an increased chance of neural tube defects (NTD) in Botswana, Africa. Herein we describe two cases of NTD in women who conceived while taking DTG as part of their antiretroviral treatment in the city of Porto Alegre, Brazil.application/pdfengThe Brazilian journal of infectious diseases. Salvador. Vol. 25, no. 2 (Mar./Apr. 2021), 101572, 4 p.HIVGravidezDefeitos do tubo neuralPorto Alegre (RS)COVID-19Neural tube defectsPregnancyDolutegravirTwo cases of neural tube defects with dolutegravir use at conception in south Brazilinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/otherinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001137454.pdf.txt001137454.pdf.txtExtracted Texttext/plain14239http://www.lume.ufrgs.br/bitstream/10183/236731/2/001137454.pdf.txt80cfa79006b58fbc4eba5ba2f0c09aa7MD52ORIGINAL001137454.pdfTexto completo (inglês)application/pdf871414http://www.lume.ufrgs.br/bitstream/10183/236731/1/001137454.pdfcdbc6b2556ee860a577e9dd6628bbd6aMD5110183/2367312022-04-20 04:50:29.903011oai:www.lume.ufrgs.br:10183/236731Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2022-04-20T07:50:29Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.pt_BR.fl_str_mv Two cases of neural tube defects with dolutegravir use at conception in south Brazil
title Two cases of neural tube defects with dolutegravir use at conception in south Brazil
spellingShingle Two cases of neural tube defects with dolutegravir use at conception in south Brazil
Kreitchmann, Regis
HIV
Gravidez
Defeitos do tubo neural
Porto Alegre (RS)
COVID-19
Neural tube defects
Pregnancy
Dolutegravir
title_short Two cases of neural tube defects with dolutegravir use at conception in south Brazil
title_full Two cases of neural tube defects with dolutegravir use at conception in south Brazil
title_fullStr Two cases of neural tube defects with dolutegravir use at conception in south Brazil
title_full_unstemmed Two cases of neural tube defects with dolutegravir use at conception in south Brazil
title_sort Two cases of neural tube defects with dolutegravir use at conception in south Brazil
author Kreitchmann, Regis
author_facet Kreitchmann, Regis
Oliveira, Fernando Rocha de
Sprinz, Eduardo
author_role author
author2 Oliveira, Fernando Rocha de
Sprinz, Eduardo
author2_role author
author
dc.contributor.author.fl_str_mv Kreitchmann, Regis
Oliveira, Fernando Rocha de
Sprinz, Eduardo
dc.subject.por.fl_str_mv HIV
Gravidez
Defeitos do tubo neural
Porto Alegre (RS)
topic HIV
Gravidez
Defeitos do tubo neural
Porto Alegre (RS)
COVID-19
Neural tube defects
Pregnancy
Dolutegravir
dc.subject.eng.fl_str_mv COVID-19
Neural tube defects
Pregnancy
Dolutegravir
description Dolutegravir (DTG) is amongst the most prescribed antiretrovirals worldwide and is recommended as first line regimen in most HIV treatment guidelines. Its use, although infrequently, had been associated to an increased chance of neural tube defects (NTD) in Botswana, Africa. Herein we describe two cases of NTD in women who conceived while taking DTG as part of their antiretroviral treatment in the city of Porto Alegre, Brazil.
publishDate 2021
dc.date.issued.fl_str_mv 2021
dc.date.accessioned.fl_str_mv 2022-04-07T04:48:29Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/other
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10183/236731
dc.identifier.issn.pt_BR.fl_str_mv 1413-8670
dc.identifier.nrb.pt_BR.fl_str_mv 001137454
identifier_str_mv 1413-8670
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url http://hdl.handle.net/10183/236731
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.pt_BR.fl_str_mv The Brazilian journal of infectious diseases. Salvador. Vol. 25, no. 2 (Mar./Apr. 2021), 101572, 4 p.
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eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
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institution UFRGS
reponame_str Repositório Institucional da UFRGS
collection Repositório Institucional da UFRGS
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