Consensus on the treatment of vitiligo : Brazilian Society of Dermatology
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/225079 |
Resumo: | Background Vitiligo is a muco-cutaneous, autoimmune, localized, or disseminated disease, which manifests through hypochromic or achromic macules, with loss in quality of life. The prevalence of vitiligo in Brazil was determined to be 0.54%. There is no on-label medication for its treatment. To date, no Brazilian consensus on the treatment of vitiligo had been written. Objectives The objective of this group of Brazilian dermatologists with experience in the treatment of this disease was to reach a consensus on the clinical and surgical treatment of vitiligo, based on articles with the best scientific evidence. Methods Seven dermatologists were invited, and each was assigned two treatment modalities to review. Each treatment (topical, systemic, and phototherapy) was reviewed by three experts. Two experts reviewed the surgical treatment. Subsequently, the coordinator compiled the different versions and drafted a text about each type of treatment. The new version was returned to all experts, who expressed their opinions and made suggestions for clarity. The final text was written by the coordinator and sent to all participants to prepare the final consensus. Results/Conclusion The experts defined the following as standard treatments of vitiligo: the use of topical corticosteroids and calcineurin inhibitors for localized and unstable cases; corticosteroid minipulse in progressive generalized vitiligo; narrowband UVB phototherapy for extensive forms of the disease. Surgical modalities should be indicated for segmental and stable generalized vitiligo. Topical and systemic anti-JAK drugs are being tested, with promising results. |
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Dellatorre, GersonAntelo, Daniela Alves PereiraBedrikow, Roberta BuenseCestari, Tania FerreiraFollador, IvoniseRamos, Daniel GontijoCastro, Caio Cesar Silva de2021-08-04T04:49:32Z20200365-0596http://hdl.handle.net/10183/225079001127857Background Vitiligo is a muco-cutaneous, autoimmune, localized, or disseminated disease, which manifests through hypochromic or achromic macules, with loss in quality of life. The prevalence of vitiligo in Brazil was determined to be 0.54%. There is no on-label medication for its treatment. To date, no Brazilian consensus on the treatment of vitiligo had been written. Objectives The objective of this group of Brazilian dermatologists with experience in the treatment of this disease was to reach a consensus on the clinical and surgical treatment of vitiligo, based on articles with the best scientific evidence. Methods Seven dermatologists were invited, and each was assigned two treatment modalities to review. Each treatment (topical, systemic, and phototherapy) was reviewed by three experts. Two experts reviewed the surgical treatment. Subsequently, the coordinator compiled the different versions and drafted a text about each type of treatment. The new version was returned to all experts, who expressed their opinions and made suggestions for clarity. The final text was written by the coordinator and sent to all participants to prepare the final consensus. Results/Conclusion The experts defined the following as standard treatments of vitiligo: the use of topical corticosteroids and calcineurin inhibitors for localized and unstable cases; corticosteroid minipulse in progressive generalized vitiligo; narrowband UVB phototherapy for extensive forms of the disease. Surgical modalities should be indicated for segmental and stable generalized vitiligo. Topical and systemic anti-JAK drugs are being tested, with promising results.application/pdfengAnais Brasileiros de Dermatologia. Rio de Janeiro. Vol. 95, supl. 1 (2020), p. 70-82VitiligoProtocolos clínicosConsensoTerapêuticaClinical protocolsCombined modality therapyConsensusTreatment outcomeVitiligoConsensus on the treatment of vitiligo : Brazilian Society of Dermatologyinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/otherinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001127857.pdf.txt001127857.pdf.txtExtracted Texttext/plain76277http://www.lume.ufrgs.br/bitstream/10183/225079/2/001127857.pdf.txt05d851a975632195cb9d51ff8d29d171MD52ORIGINAL001127857.pdfTexto completo (inglês)application/pdf1787660http://www.lume.ufrgs.br/bitstream/10183/225079/1/001127857.pdffa9368eb080b51002e6538daa381a1b8MD5110183/2250792023-06-24 03:39:07.877385oai:www.lume.ufrgs.br:10183/225079Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2023-06-24T06:39:07Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Consensus on the treatment of vitiligo : Brazilian Society of Dermatology |
title |
Consensus on the treatment of vitiligo : Brazilian Society of Dermatology |
spellingShingle |
Consensus on the treatment of vitiligo : Brazilian Society of Dermatology Dellatorre, Gerson Vitiligo Protocolos clínicos Consenso Terapêutica Clinical protocols Combined modality therapy Consensus Treatment outcome Vitiligo |
title_short |
Consensus on the treatment of vitiligo : Brazilian Society of Dermatology |
title_full |
Consensus on the treatment of vitiligo : Brazilian Society of Dermatology |
title_fullStr |
Consensus on the treatment of vitiligo : Brazilian Society of Dermatology |
title_full_unstemmed |
Consensus on the treatment of vitiligo : Brazilian Society of Dermatology |
title_sort |
Consensus on the treatment of vitiligo : Brazilian Society of Dermatology |
author |
Dellatorre, Gerson |
author_facet |
Dellatorre, Gerson Antelo, Daniela Alves Pereira Bedrikow, Roberta Buense Cestari, Tania Ferreira Follador, Ivonise Ramos, Daniel Gontijo Castro, Caio Cesar Silva de |
author_role |
author |
author2 |
Antelo, Daniela Alves Pereira Bedrikow, Roberta Buense Cestari, Tania Ferreira Follador, Ivonise Ramos, Daniel Gontijo Castro, Caio Cesar Silva de |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Dellatorre, Gerson Antelo, Daniela Alves Pereira Bedrikow, Roberta Buense Cestari, Tania Ferreira Follador, Ivonise Ramos, Daniel Gontijo Castro, Caio Cesar Silva de |
dc.subject.por.fl_str_mv |
Vitiligo Protocolos clínicos Consenso Terapêutica |
topic |
Vitiligo Protocolos clínicos Consenso Terapêutica Clinical protocols Combined modality therapy Consensus Treatment outcome Vitiligo |
dc.subject.eng.fl_str_mv |
Clinical protocols Combined modality therapy Consensus Treatment outcome Vitiligo |
description |
Background Vitiligo is a muco-cutaneous, autoimmune, localized, or disseminated disease, which manifests through hypochromic or achromic macules, with loss in quality of life. The prevalence of vitiligo in Brazil was determined to be 0.54%. There is no on-label medication for its treatment. To date, no Brazilian consensus on the treatment of vitiligo had been written. Objectives The objective of this group of Brazilian dermatologists with experience in the treatment of this disease was to reach a consensus on the clinical and surgical treatment of vitiligo, based on articles with the best scientific evidence. Methods Seven dermatologists were invited, and each was assigned two treatment modalities to review. Each treatment (topical, systemic, and phototherapy) was reviewed by three experts. Two experts reviewed the surgical treatment. Subsequently, the coordinator compiled the different versions and drafted a text about each type of treatment. The new version was returned to all experts, who expressed their opinions and made suggestions for clarity. The final text was written by the coordinator and sent to all participants to prepare the final consensus. Results/Conclusion The experts defined the following as standard treatments of vitiligo: the use of topical corticosteroids and calcineurin inhibitors for localized and unstable cases; corticosteroid minipulse in progressive generalized vitiligo; narrowband UVB phototherapy for extensive forms of the disease. Surgical modalities should be indicated for segmental and stable generalized vitiligo. Topical and systemic anti-JAK drugs are being tested, with promising results. |
publishDate |
2020 |
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2020 |
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2021-08-04T04:49:32Z |
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http://hdl.handle.net/10183/225079 |
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eng |
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Anais Brasileiros de Dermatologia. Rio de Janeiro. Vol. 95, supl. 1 (2020), p. 70-82 |
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