Revisiting hydroxychloroquine and chloroquine for patients with chronic immunity-mediated inflammatory rheumatic diseases

Detalhes bibliográficos
Autor(a) principal: Reis Neto, Edgard Torres dos
Data de Publicação: 2020
Outros Autores: Kakehasi, Adriana Maria, Pinheiro, Marcelo de Medeiros, Ferreira, Gilda Aparecida, Marques, Cláudia Diniz Lopes, Mota, Licia Maria Henrique da, Paiva, Eduardo dos Santos, Pileggi, Gecilmara Cristina Salviato, Sato, Emilia Inoue, Reis, Ana Paula Monteiro Gomides, Xavier, Ricardo Machado, Provenza, José Roberto
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFRGS
Texto Completo: http://hdl.handle.net/10183/229323
Resumo: Hydroxychloroquine and chloroquine, also known as antimalarial drugs, are widely used in the treatment of rheumatic diseases and have recently become the focus of attention because of the ongoing COVID-19 pandemic. Rheumatologists have been using antimalarials to manage patients with chronic immune-mediated inflammatory rheumatic diseases for decades. It is an appropriate time to review their immunomodulatory and anti-inflammatory mechanisms impact on disease activity and survival of systemic lupus erythematosus patient, including antiplatelet effect, metabolic and lipid benefits. We also discuss possible adverse effects, adding a practical and comprehensive approach to monitoring rheumatic patients during treatment with these drugs.
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spelling Reis Neto, Edgard Torres dosKakehasi, Adriana MariaPinheiro, Marcelo de MedeirosFerreira, Gilda AparecidaMarques, Cláudia Diniz LopesMota, Licia Maria Henrique daPaiva, Eduardo dos SantosPileggi, Gecilmara Cristina SalviatoSato, Emilia InoueReis, Ana Paula Monteiro GomidesXavier, Ricardo MachadoProvenza, José Roberto2021-09-01T04:25:52Z20202523-3106http://hdl.handle.net/10183/229323001130599Hydroxychloroquine and chloroquine, also known as antimalarial drugs, are widely used in the treatment of rheumatic diseases and have recently become the focus of attention because of the ongoing COVID-19 pandemic. Rheumatologists have been using antimalarials to manage patients with chronic immune-mediated inflammatory rheumatic diseases for decades. It is an appropriate time to review their immunomodulatory and anti-inflammatory mechanisms impact on disease activity and survival of systemic lupus erythematosus patient, including antiplatelet effect, metabolic and lipid benefits. We also discuss possible adverse effects, adding a practical and comprehensive approach to monitoring rheumatic patients during treatment with these drugs.application/pdfengAdvances in rheumatology. São Paulo. Vol. 60 (2020), 32, 11 p.Doenças reumáticasDoença crônicaInflamaçãoCloroquinaHidroxicloroquinaHydroxychloroquineChloroquineAntimalarialsChronic immune-mediated inflammatory rheumatic diseasesRevisiting hydroxychloroquine and chloroquine for patients with chronic immunity-mediated inflammatory rheumatic diseasesinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/otherinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001130599.pdf.txt001130599.pdf.txtExtracted Texttext/plain49233http://www.lume.ufrgs.br/bitstream/10183/229323/2/001130599.pdf.txt1172cf05df07bfbd6173ba6a27cd97b2MD52ORIGINAL001130599.pdfTexto completo (inglês)application/pdf1853639http://www.lume.ufrgs.br/bitstream/10183/229323/1/001130599.pdfdb5ec479ae0a6a18cd9c6d255de02f17MD5110183/2293232023-05-24 03:28:48.669786oai:www.lume.ufrgs.br:10183/229323Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2023-05-24T06:28:48Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.pt_BR.fl_str_mv Revisiting hydroxychloroquine and chloroquine for patients with chronic immunity-mediated inflammatory rheumatic diseases
title Revisiting hydroxychloroquine and chloroquine for patients with chronic immunity-mediated inflammatory rheumatic diseases
spellingShingle Revisiting hydroxychloroquine and chloroquine for patients with chronic immunity-mediated inflammatory rheumatic diseases
Reis Neto, Edgard Torres dos
Doenças reumáticas
Doença crônica
Inflamação
Cloroquina
Hidroxicloroquina
Hydroxychloroquine
Chloroquine
Antimalarials
Chronic immune-mediated inflammatory rheumatic diseases
title_short Revisiting hydroxychloroquine and chloroquine for patients with chronic immunity-mediated inflammatory rheumatic diseases
title_full Revisiting hydroxychloroquine and chloroquine for patients with chronic immunity-mediated inflammatory rheumatic diseases
title_fullStr Revisiting hydroxychloroquine and chloroquine for patients with chronic immunity-mediated inflammatory rheumatic diseases
title_full_unstemmed Revisiting hydroxychloroquine and chloroquine for patients with chronic immunity-mediated inflammatory rheumatic diseases
title_sort Revisiting hydroxychloroquine and chloroquine for patients with chronic immunity-mediated inflammatory rheumatic diseases
author Reis Neto, Edgard Torres dos
author_facet Reis Neto, Edgard Torres dos
Kakehasi, Adriana Maria
Pinheiro, Marcelo de Medeiros
Ferreira, Gilda Aparecida
Marques, Cláudia Diniz Lopes
Mota, Licia Maria Henrique da
Paiva, Eduardo dos Santos
Pileggi, Gecilmara Cristina Salviato
Sato, Emilia Inoue
Reis, Ana Paula Monteiro Gomides
Xavier, Ricardo Machado
Provenza, José Roberto
author_role author
author2 Kakehasi, Adriana Maria
Pinheiro, Marcelo de Medeiros
Ferreira, Gilda Aparecida
Marques, Cláudia Diniz Lopes
Mota, Licia Maria Henrique da
Paiva, Eduardo dos Santos
Pileggi, Gecilmara Cristina Salviato
Sato, Emilia Inoue
Reis, Ana Paula Monteiro Gomides
Xavier, Ricardo Machado
Provenza, José Roberto
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Reis Neto, Edgard Torres dos
Kakehasi, Adriana Maria
Pinheiro, Marcelo de Medeiros
Ferreira, Gilda Aparecida
Marques, Cláudia Diniz Lopes
Mota, Licia Maria Henrique da
Paiva, Eduardo dos Santos
Pileggi, Gecilmara Cristina Salviato
Sato, Emilia Inoue
Reis, Ana Paula Monteiro Gomides
Xavier, Ricardo Machado
Provenza, José Roberto
dc.subject.por.fl_str_mv Doenças reumáticas
Doença crônica
Inflamação
Cloroquina
Hidroxicloroquina
topic Doenças reumáticas
Doença crônica
Inflamação
Cloroquina
Hidroxicloroquina
Hydroxychloroquine
Chloroquine
Antimalarials
Chronic immune-mediated inflammatory rheumatic diseases
dc.subject.eng.fl_str_mv Hydroxychloroquine
Chloroquine
Antimalarials
Chronic immune-mediated inflammatory rheumatic diseases
description Hydroxychloroquine and chloroquine, also known as antimalarial drugs, are widely used in the treatment of rheumatic diseases and have recently become the focus of attention because of the ongoing COVID-19 pandemic. Rheumatologists have been using antimalarials to manage patients with chronic immune-mediated inflammatory rheumatic diseases for decades. It is an appropriate time to review their immunomodulatory and anti-inflammatory mechanisms impact on disease activity and survival of systemic lupus erythematosus patient, including antiplatelet effect, metabolic and lipid benefits. We also discuss possible adverse effects, adding a practical and comprehensive approach to monitoring rheumatic patients during treatment with these drugs.
publishDate 2020
dc.date.issued.fl_str_mv 2020
dc.date.accessioned.fl_str_mv 2021-09-01T04:25:52Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/other
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10183/229323
dc.identifier.issn.pt_BR.fl_str_mv 2523-3106
dc.identifier.nrb.pt_BR.fl_str_mv 001130599
identifier_str_mv 2523-3106
001130599
url http://hdl.handle.net/10183/229323
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.pt_BR.fl_str_mv Advances in rheumatology. São Paulo. Vol. 60 (2020), 32, 11 p.
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFRGS
instname:Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
instname_str Universidade Federal do Rio Grande do Sul (UFRGS)
instacron_str UFRGS
institution UFRGS
reponame_str Repositório Institucional da UFRGS
collection Repositório Institucional da UFRGS
bitstream.url.fl_str_mv http://www.lume.ufrgs.br/bitstream/10183/229323/2/001130599.pdf.txt
http://www.lume.ufrgs.br/bitstream/10183/229323/1/001130599.pdf
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repository.name.fl_str_mv Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)
repository.mail.fl_str_mv
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