Associations of total legume, pulse, and soy consumption with incident type 2 diabetes : federated meta-analysis of 27 studies from diverse world regions
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/243187 |
Resumo: | Background: The consumption of legumes is promoted as part of a healthy diet in many countries but associations of total and types of legume consumption with type 2 diabetes (T2D) are not well established. Analyses across diverse populations are lacking despite the availability of unpublished legume consumption data in prospective cohort studies. Objective: To examine the prospective associations of total and types of legume intake with the risk of incident T2D. Methods: Meta-analyses of associations between total legume, pulse, and soy consumption and T2D were conducted using a federated approach without physical data-pooling. Prospective cohorts were included if legume exposure and T2D outcome data were available and the cohort investigators agreed to participate. We estimated incidence rate ratios (IRRs) and CIs of associations using individual participant data including ≤42,473 incident cases among 807,785 adults without diabetes in 27 cohorts across the Americas, Eastern Mediterranean, Europe, and Western Pacific. Randomeffects meta-analysis was used to combine effect estimates and estimate heterogeneity. Results: Median total legume intake ranged from 0–140 g/d across cohorts. We observed a weak positive association between total legume consumption and T2D (IRR = 1.02, 95% CI: 1.01 to 1.04) per 20 g/d higher intake, with moderately high heterogeneity (I2 = 74%). Analysis by region showed no evidence of associations in the Americas, Eastern Mediterranean, andWestern Pacific. The positive association in Europe (IRR = 1.05, 95% CI: 1.01 to 1.10, I2 = 82%) was mainly driven by studies from Germany, UK, and Sweden. No evidence of associationswas observed for the consumption of pulses or soy. Conclusions: These findings suggest no evidence of an association of legume intakes with T2D in several world regions. The positive association observed in some European studies warrants further investigation relating to overall dietary contexts in which legumes are consumed, including accompanying foods which may be positively associated with T2D. |
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Pearce, MatthewForouhi, Nita G.Canhada, Scheine LeiteDuncan, Bruce Bartholow2022-07-20T04:48:57Z20210022-3166http://hdl.handle.net/10183/243187001145064Background: The consumption of legumes is promoted as part of a healthy diet in many countries but associations of total and types of legume consumption with type 2 diabetes (T2D) are not well established. Analyses across diverse populations are lacking despite the availability of unpublished legume consumption data in prospective cohort studies. Objective: To examine the prospective associations of total and types of legume intake with the risk of incident T2D. Methods: Meta-analyses of associations between total legume, pulse, and soy consumption and T2D were conducted using a federated approach without physical data-pooling. Prospective cohorts were included if legume exposure and T2D outcome data were available and the cohort investigators agreed to participate. We estimated incidence rate ratios (IRRs) and CIs of associations using individual participant data including ≤42,473 incident cases among 807,785 adults without diabetes in 27 cohorts across the Americas, Eastern Mediterranean, Europe, and Western Pacific. Randomeffects meta-analysis was used to combine effect estimates and estimate heterogeneity. Results: Median total legume intake ranged from 0–140 g/d across cohorts. We observed a weak positive association between total legume consumption and T2D (IRR = 1.02, 95% CI: 1.01 to 1.04) per 20 g/d higher intake, with moderately high heterogeneity (I2 = 74%). Analysis by region showed no evidence of associations in the Americas, Eastern Mediterranean, andWestern Pacific. The positive association in Europe (IRR = 1.05, 95% CI: 1.01 to 1.10, I2 = 82%) was mainly driven by studies from Germany, UK, and Sweden. No evidence of associationswas observed for the consumption of pulses or soy. Conclusions: These findings suggest no evidence of an association of legume intakes with T2D in several world regions. The positive association observed in some European studies warrants further investigation relating to overall dietary contexts in which legumes are consumed, including accompanying foods which may be positively associated with T2D.application/pdfengThe journal of nutrition. Rockville, MD. Vol. 151, no. 5 (2021), p. 1231–1240VerdurasDiabetes mellitusFabaceaeArachisLens (Planta)ErvilhasSojaCicerLegumesPulseBeanPeanutLentilPeaSoyChickpeaAssociations of total legume, pulse, and soy consumption with incident type 2 diabetes : federated meta-analysis of 27 studies from diverse world regionsEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001145064.pdf.txt001145064.pdf.txtExtracted Texttext/plain57395http://www.lume.ufrgs.br/bitstream/10183/243187/2/001145064.pdf.txtb567ca57387571c173a72a5c354d1a43MD52ORIGINAL001145064.pdfTexto completo (inglês)application/pdf1102779http://www.lume.ufrgs.br/bitstream/10183/243187/1/001145064.pdf874f5d448a0d84a01ba41b7a4abca25bMD5110183/2431872023-05-27 03:40:57.07337oai:www.lume.ufrgs.br:10183/243187Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2023-05-27T06:40:57Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Associations of total legume, pulse, and soy consumption with incident type 2 diabetes : federated meta-analysis of 27 studies from diverse world regions |
title |
Associations of total legume, pulse, and soy consumption with incident type 2 diabetes : federated meta-analysis of 27 studies from diverse world regions |
spellingShingle |
Associations of total legume, pulse, and soy consumption with incident type 2 diabetes : federated meta-analysis of 27 studies from diverse world regions Pearce, Matthew Verduras Diabetes mellitus Fabaceae Arachis Lens (Planta) Ervilhas Soja Cicer Legumes Pulse Bean Peanut Lentil Pea Soy Chickpea |
title_short |
Associations of total legume, pulse, and soy consumption with incident type 2 diabetes : federated meta-analysis of 27 studies from diverse world regions |
title_full |
Associations of total legume, pulse, and soy consumption with incident type 2 diabetes : federated meta-analysis of 27 studies from diverse world regions |
title_fullStr |
Associations of total legume, pulse, and soy consumption with incident type 2 diabetes : federated meta-analysis of 27 studies from diverse world regions |
title_full_unstemmed |
Associations of total legume, pulse, and soy consumption with incident type 2 diabetes : federated meta-analysis of 27 studies from diverse world regions |
title_sort |
Associations of total legume, pulse, and soy consumption with incident type 2 diabetes : federated meta-analysis of 27 studies from diverse world regions |
author |
Pearce, Matthew |
author_facet |
Pearce, Matthew Forouhi, Nita G. Canhada, Scheine Leite Duncan, Bruce Bartholow |
author_role |
author |
author2 |
Forouhi, Nita G. Canhada, Scheine Leite Duncan, Bruce Bartholow |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Pearce, Matthew Forouhi, Nita G. Canhada, Scheine Leite Duncan, Bruce Bartholow |
dc.subject.por.fl_str_mv |
Verduras Diabetes mellitus Fabaceae Arachis Lens (Planta) Ervilhas Soja Cicer |
topic |
Verduras Diabetes mellitus Fabaceae Arachis Lens (Planta) Ervilhas Soja Cicer Legumes Pulse Bean Peanut Lentil Pea Soy Chickpea |
dc.subject.eng.fl_str_mv |
Legumes Pulse Bean Peanut Lentil Pea Soy Chickpea |
description |
Background: The consumption of legumes is promoted as part of a healthy diet in many countries but associations of total and types of legume consumption with type 2 diabetes (T2D) are not well established. Analyses across diverse populations are lacking despite the availability of unpublished legume consumption data in prospective cohort studies. Objective: To examine the prospective associations of total and types of legume intake with the risk of incident T2D. Methods: Meta-analyses of associations between total legume, pulse, and soy consumption and T2D were conducted using a federated approach without physical data-pooling. Prospective cohorts were included if legume exposure and T2D outcome data were available and the cohort investigators agreed to participate. We estimated incidence rate ratios (IRRs) and CIs of associations using individual participant data including ≤42,473 incident cases among 807,785 adults without diabetes in 27 cohorts across the Americas, Eastern Mediterranean, Europe, and Western Pacific. Randomeffects meta-analysis was used to combine effect estimates and estimate heterogeneity. Results: Median total legume intake ranged from 0–140 g/d across cohorts. We observed a weak positive association between total legume consumption and T2D (IRR = 1.02, 95% CI: 1.01 to 1.04) per 20 g/d higher intake, with moderately high heterogeneity (I2 = 74%). Analysis by region showed no evidence of associations in the Americas, Eastern Mediterranean, andWestern Pacific. The positive association in Europe (IRR = 1.05, 95% CI: 1.01 to 1.10, I2 = 82%) was mainly driven by studies from Germany, UK, and Sweden. No evidence of associationswas observed for the consumption of pulses or soy. Conclusions: These findings suggest no evidence of an association of legume intakes with T2D in several world regions. The positive association observed in some European studies warrants further investigation relating to overall dietary contexts in which legumes are consumed, including accompanying foods which may be positively associated with T2D. |
publishDate |
2021 |
dc.date.issued.fl_str_mv |
2021 |
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2022-07-20T04:48:57Z |
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The journal of nutrition. Rockville, MD. Vol. 151, no. 5 (2021), p. 1231–1240 |
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