Psychopharmacology and psychotherapy for the treatment of adults with ADHD : a systematic review of available meta-analyses
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/95164 |
Resumo: | Objective/Introduction. Attention-deficit/hyperactivity disorder (ADHD) in adult life is a prevalent condition. We systematically reviewed the literature available by searching for meta-analyses assessing pharmacological and psychosocial interventions for adults with ADHD. Methods. Using wide-ranging search terms, we retrieved 191 titles from the PubMed and Cochrane databases. Two independent evaluators judged all abstracts. Only meta-analyses about the treatment of adults with ADHD were included. Information from meta-analyses found was systematically extracted by 3 independent evaluators. Results. Eight meta-analyses were identified. Results from those meta-analyses suggest that stimulants are effective in decreasing ADHD symptoms on a short-term basis with a medium to large effect size (ES). Short-acting stimulants might be superior to long-acting stimulants, but no data on difference in adherence are available for the comparison of these two types of formulation. Bupropion is superior to placebo but less effective than stimulants. No conclusions about the impact of psychosocial interventions can be drawn based on meta-analyses so far. Discussion. The efficacy of stimulants in reducing ADHD symptoms for adults is well documented in metaanalyses, but there is a concerning lack of meta-analysis about other treatment interventions. Conclusion. The available meta-analytic literature does not cover questions of essential clinical relevance for adults with ADHD. |
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Moriyama, Taís SilveiraPolanczyk, Guilherme VanoniTerzi, Fernanda SilvaFaria, Kauy Victor MartinezRohde, Luis Augusto Paim2014-05-13T02:03:56Z20131092-8529http://hdl.handle.net/10183/95164000914286Objective/Introduction. Attention-deficit/hyperactivity disorder (ADHD) in adult life is a prevalent condition. We systematically reviewed the literature available by searching for meta-analyses assessing pharmacological and psychosocial interventions for adults with ADHD. Methods. Using wide-ranging search terms, we retrieved 191 titles from the PubMed and Cochrane databases. Two independent evaluators judged all abstracts. Only meta-analyses about the treatment of adults with ADHD were included. Information from meta-analyses found was systematically extracted by 3 independent evaluators. Results. Eight meta-analyses were identified. Results from those meta-analyses suggest that stimulants are effective in decreasing ADHD symptoms on a short-term basis with a medium to large effect size (ES). Short-acting stimulants might be superior to long-acting stimulants, but no data on difference in adherence are available for the comparison of these two types of formulation. Bupropion is superior to placebo but less effective than stimulants. No conclusions about the impact of psychosocial interventions can be drawn based on meta-analyses so far. Discussion. The efficacy of stimulants in reducing ADHD symptoms for adults is well documented in metaanalyses, but there is a concerning lack of meta-analysis about other treatment interventions. Conclusion. The available meta-analytic literature does not cover questions of essential clinical relevance for adults with ADHD.application/pdfengCNS spectrums. New York. Vol. 18, no. 6 (Dec. 2013), p. 296-306.Transtorno do déficit de atenção com hiperatividadeAdultoPsicofarmacologiaMetanálisePsicoterapiaADHDAdultsInattentionStimulantsTreatmentPsychopharmacology and psychotherapy for the treatment of adults with ADHD : a systematic review of available meta-analysesEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL000914286.pdf000914286.pdfTexto completo (inglês)application/pdf275333http://www.lume.ufrgs.br/bitstream/10183/95164/1/000914286.pdf6d9b006c5e3a9c53c425ad7f778b7c0eMD51TEXT000914286.pdf.txt000914286.pdf.txtExtracted Texttext/plain45523http://www.lume.ufrgs.br/bitstream/10183/95164/2/000914286.pdf.txt68118ca0c30a62eed2ffca0f38d50206MD52THUMBNAIL000914286.pdf.jpg000914286.pdf.jpgGenerated Thumbnailimage/jpeg1476http://www.lume.ufrgs.br/bitstream/10183/95164/3/000914286.pdf.jpg83bdb082d6727c0a42d711bd44c65b1bMD5310183/951642021-03-09 04:26:53.234662oai:www.lume.ufrgs.br:10183/95164Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2021-03-09T07:26:53Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Psychopharmacology and psychotherapy for the treatment of adults with ADHD : a systematic review of available meta-analyses |
title |
Psychopharmacology and psychotherapy for the treatment of adults with ADHD : a systematic review of available meta-analyses |
spellingShingle |
Psychopharmacology and psychotherapy for the treatment of adults with ADHD : a systematic review of available meta-analyses Moriyama, Taís Silveira Transtorno do déficit de atenção com hiperatividade Adulto Psicofarmacologia Metanálise Psicoterapia ADHD Adults Inattention Stimulants Treatment |
title_short |
Psychopharmacology and psychotherapy for the treatment of adults with ADHD : a systematic review of available meta-analyses |
title_full |
Psychopharmacology and psychotherapy for the treatment of adults with ADHD : a systematic review of available meta-analyses |
title_fullStr |
Psychopharmacology and psychotherapy for the treatment of adults with ADHD : a systematic review of available meta-analyses |
title_full_unstemmed |
Psychopharmacology and psychotherapy for the treatment of adults with ADHD : a systematic review of available meta-analyses |
title_sort |
Psychopharmacology and psychotherapy for the treatment of adults with ADHD : a systematic review of available meta-analyses |
author |
Moriyama, Taís Silveira |
author_facet |
Moriyama, Taís Silveira Polanczyk, Guilherme Vanoni Terzi, Fernanda Silva Faria, Kauy Victor Martinez Rohde, Luis Augusto Paim |
author_role |
author |
author2 |
Polanczyk, Guilherme Vanoni Terzi, Fernanda Silva Faria, Kauy Victor Martinez Rohde, Luis Augusto Paim |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Moriyama, Taís Silveira Polanczyk, Guilherme Vanoni Terzi, Fernanda Silva Faria, Kauy Victor Martinez Rohde, Luis Augusto Paim |
dc.subject.por.fl_str_mv |
Transtorno do déficit de atenção com hiperatividade Adulto Psicofarmacologia Metanálise Psicoterapia |
topic |
Transtorno do déficit de atenção com hiperatividade Adulto Psicofarmacologia Metanálise Psicoterapia ADHD Adults Inattention Stimulants Treatment |
dc.subject.eng.fl_str_mv |
ADHD Adults Inattention Stimulants Treatment |
description |
Objective/Introduction. Attention-deficit/hyperactivity disorder (ADHD) in adult life is a prevalent condition. We systematically reviewed the literature available by searching for meta-analyses assessing pharmacological and psychosocial interventions for adults with ADHD. Methods. Using wide-ranging search terms, we retrieved 191 titles from the PubMed and Cochrane databases. Two independent evaluators judged all abstracts. Only meta-analyses about the treatment of adults with ADHD were included. Information from meta-analyses found was systematically extracted by 3 independent evaluators. Results. Eight meta-analyses were identified. Results from those meta-analyses suggest that stimulants are effective in decreasing ADHD symptoms on a short-term basis with a medium to large effect size (ES). Short-acting stimulants might be superior to long-acting stimulants, but no data on difference in adherence are available for the comparison of these two types of formulation. Bupropion is superior to placebo but less effective than stimulants. No conclusions about the impact of psychosocial interventions can be drawn based on meta-analyses so far. Discussion. The efficacy of stimulants in reducing ADHD symptoms for adults is well documented in metaanalyses, but there is a concerning lack of meta-analysis about other treatment interventions. Conclusion. The available meta-analytic literature does not cover questions of essential clinical relevance for adults with ADHD. |
publishDate |
2013 |
dc.date.issued.fl_str_mv |
2013 |
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2014-05-13T02:03:56Z |
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dc.language.iso.fl_str_mv |
eng |
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dc.relation.ispartof.pt_BR.fl_str_mv |
CNS spectrums. New York. Vol. 18, no. 6 (Dec. 2013), p. 296-306. |
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