Frequency of brain tissue donation for research after suicide

• Autor(a) principal: Longaray, Vanessa Kenne
• Data de Publicação: 2017
• Outros Autores: Padoan, Carolina Stopinski, Goi, Pedro Domingues, Fonseca, Rodrigo Chiavaro da, Vieira, Daniel Chaves, Oliveira, Francine Hehn de, Kapczinski, Flávio Pereira
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UFRGS
• Texto Completo: http://hdl.handle.net/10183/183866
• topic: Consentimento livre e esclarecido; Doadores de tecidos; Autópsia; Doenças neurodegenerativas; Brasil; Suicide; Ethics; Community mental health; Molecular biology; Neuroanatomy

Objectives: To describe the frequency of brain tissue donation for research purposes by families of individuals that committed suicide. Methods: All requests for brain tissue donation to a brain biorepository made to the families of individuals aged 18-60 years who had committed suicide between March 2014 and February 2016 were included. Cases presenting with brain damage due to acute trauma were excluded. Results: Fifty-six cases of suicide were reported. Of these, 24 fulfilled the exclusion criteria, and 11 others were excluded because no next of kin was found to provide informed consent. Of the 21 remaining cases, brain tissue donation was authorized in nine (tissue fragments in seven and the entire organ in two). Conclusions: Donation of brain tissue from suicide cases for research purposes is feasible. The acceptance rate of 42.8% in our sample is in accordance with international data on such donations, and similar to rates reported for neurodegenerative diseases.