Mild environmental intervention in mother-infant interactions reduces social play behavior in rats
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/114597 |
Resumo: | During early life, animals are sensitive to environmental events that may lead to short-term and long-lasting changes in their neurobiology and behavior, which could be related to increased risk for psychopathology. Neonatal handling is an experimental intervention in the mother–infant relationship. Based on previous studies, it is known to decrease rat pups’ preference for maternal cues. Handling also reduces social, sexual, and fear behavior in adult animals, which is related to underlying neuroendocrine alterations. One prominent feature of adolescence is the high frequency of social behaviors such as play that appear to be necessary for proper socioemotional development. The objective of the present study was to investigate the effect of repeatedly handling pups on social play behavior during the neonatal period in juvenile Wistar rats. We found that handling consistently decreased pouncing, wrestling, and chasing play behavior on postnatal days (PND) 25, 30, and 35 compared with non-handled juveniles. As expected, sex differences were also found. Consistent with previous studies in infant and adult rats, the neonatal handling procedure also reduced affiliative behaviors in juvenile animals. The precise mechanisms by which this early intervention leads to these alterations in offspring remain to be determined, but the cumulative effects of briefly disrupting the mother-infant relationship that caused the neonatal handling may be one possible explanation. |
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Karkow, Ana Raquel MenezesLucion, Aldo Bolten2015-03-28T01:57:39Z20131983-3288http://hdl.handle.net/10183/114597000938297During early life, animals are sensitive to environmental events that may lead to short-term and long-lasting changes in their neurobiology and behavior, which could be related to increased risk for psychopathology. Neonatal handling is an experimental intervention in the mother–infant relationship. Based on previous studies, it is known to decrease rat pups’ preference for maternal cues. Handling also reduces social, sexual, and fear behavior in adult animals, which is related to underlying neuroendocrine alterations. One prominent feature of adolescence is the high frequency of social behaviors such as play that appear to be necessary for proper socioemotional development. The objective of the present study was to investigate the effect of repeatedly handling pups on social play behavior during the neonatal period in juvenile Wistar rats. We found that handling consistently decreased pouncing, wrestling, and chasing play behavior on postnatal days (PND) 25, 30, and 35 compared with non-handled juveniles. As expected, sex differences were also found. Consistent with previous studies in infant and adult rats, the neonatal handling procedure also reduced affiliative behaviors in juvenile animals. The precise mechanisms by which this early intervention leads to these alterations in offspring remain to be determined, but the cumulative effects of briefly disrupting the mother-infant relationship that caused the neonatal handling may be one possible explanation.application/pdfengPsychology & neuroscience. Rio de Janeiro. Vol. 6, n. 1 (jan-jun. 2013), p. 39-44Relações mãe-filhoComportamento animalComportamento socialManipulação neonatalEarly life interventionNeonatal handlingPlay behaviorSocial interactionJuvenile ratsMild environmental intervention in mother-infant interactions reduces social play behavior in ratsinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/otherinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL000938297.pdf000938297.pdfTexto completo (inglês)application/pdf319363http://www.lume.ufrgs.br/bitstream/10183/114597/1/000938297.pdfa8e185191086bf87819d8eb6e53fbaebMD51TEXT000938297.pdf.txt000938297.pdf.txtExtracted Texttext/plain27779http://www.lume.ufrgs.br/bitstream/10183/114597/2/000938297.pdf.txt2641df18d7cd433588df6710ceb4196bMD52THUMBNAIL000938297.pdf.jpg000938297.pdf.jpgGenerated Thumbnailimage/jpeg2281http://www.lume.ufrgs.br/bitstream/10183/114597/3/000938297.pdf.jpg9b4517d32afc7514d32d08b39287cc9cMD5310183/1145972021-09-18 04:51:32.482955oai:www.lume.ufrgs.br:10183/114597Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2021-09-18T07:51:32Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Mild environmental intervention in mother-infant interactions reduces social play behavior in rats |
title |
Mild environmental intervention in mother-infant interactions reduces social play behavior in rats |
spellingShingle |
Mild environmental intervention in mother-infant interactions reduces social play behavior in rats Karkow, Ana Raquel Menezes Relações mãe-filho Comportamento animal Comportamento social Manipulação neonatal Early life intervention Neonatal handling Play behavior Social interaction Juvenile rats |
title_short |
Mild environmental intervention in mother-infant interactions reduces social play behavior in rats |
title_full |
Mild environmental intervention in mother-infant interactions reduces social play behavior in rats |
title_fullStr |
Mild environmental intervention in mother-infant interactions reduces social play behavior in rats |
title_full_unstemmed |
Mild environmental intervention in mother-infant interactions reduces social play behavior in rats |
title_sort |
Mild environmental intervention in mother-infant interactions reduces social play behavior in rats |
author |
Karkow, Ana Raquel Menezes |
author_facet |
Karkow, Ana Raquel Menezes Lucion, Aldo Bolten |
author_role |
author |
author2 |
Lucion, Aldo Bolten |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Karkow, Ana Raquel Menezes Lucion, Aldo Bolten |
dc.subject.por.fl_str_mv |
Relações mãe-filho Comportamento animal Comportamento social Manipulação neonatal |
topic |
Relações mãe-filho Comportamento animal Comportamento social Manipulação neonatal Early life intervention Neonatal handling Play behavior Social interaction Juvenile rats |
dc.subject.eng.fl_str_mv |
Early life intervention Neonatal handling Play behavior Social interaction Juvenile rats |
description |
During early life, animals are sensitive to environmental events that may lead to short-term and long-lasting changes in their neurobiology and behavior, which could be related to increased risk for psychopathology. Neonatal handling is an experimental intervention in the mother–infant relationship. Based on previous studies, it is known to decrease rat pups’ preference for maternal cues. Handling also reduces social, sexual, and fear behavior in adult animals, which is related to underlying neuroendocrine alterations. One prominent feature of adolescence is the high frequency of social behaviors such as play that appear to be necessary for proper socioemotional development. The objective of the present study was to investigate the effect of repeatedly handling pups on social play behavior during the neonatal period in juvenile Wistar rats. We found that handling consistently decreased pouncing, wrestling, and chasing play behavior on postnatal days (PND) 25, 30, and 35 compared with non-handled juveniles. As expected, sex differences were also found. Consistent with previous studies in infant and adult rats, the neonatal handling procedure also reduced affiliative behaviors in juvenile animals. The precise mechanisms by which this early intervention leads to these alterations in offspring remain to be determined, but the cumulative effects of briefly disrupting the mother-infant relationship that caused the neonatal handling may be one possible explanation. |
publishDate |
2013 |
dc.date.issued.fl_str_mv |
2013 |
dc.date.accessioned.fl_str_mv |
2015-03-28T01:57:39Z |
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info:eu-repo/semantics/article info:eu-repo/semantics/other |
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article |
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publishedVersion |
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http://hdl.handle.net/10183/114597 |
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1983-3288 |
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000938297 |
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http://hdl.handle.net/10183/114597 |
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eng |
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eng |
dc.relation.ispartof.pt_BR.fl_str_mv |
Psychology & neuroscience. Rio de Janeiro. Vol. 6, n. 1 (jan-jun. 2013), p. 39-44 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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