Comportamento dos marcadores inflamatórios e de injúria miocárdica na cirurgia cardíaca : correlação laboratorial com quadro clínico de síndrome pós-pericardiotomia
Autor(a) principal: | |
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Data de Publicação: | 2003 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/19684 |
Resumo: | Objective- To verify the association of serum markers of myocardial injury, such as troponin I, creatinine kinase, and creatinine kinase isoenzyme MB, and inflammatory markers, such as tumor necrosis factor alpha (TNF-alpha), C-reactive protein, and the erythrocyte sedimentation rate in the perioperative period of cardiac surgery, with the occurrence of possible postpericardiotomy syndrome. Methods- This was a cohort study with 96 patients undergoing cardiac surgery assessed at the following 4 different time periods: the day before surgery (D0); the 3rd postoperative day (D3); between the 7th and 10th postoperative days (D7-10); and the 30th postoperative day (D30). During each period, we evaluated demo- graphic variables (sex and age), surgical variables (type and duration , extracorporeal circulation), and serum dosages of the markers of myocardial injury and inflam- matory response. Results - Of all patients, 12 (12.5%) met the clinical criteria for a diagnosis of postpericardiotomy syndrome, and their mean age was 10.3 years lower than the age of the others (P=0.02). The results of the serum markers for tissue injury and inflammatory response were not signifi- cantly different between the 2 assessed groups. No signifi- cant difference existed regarding either surgery duration or extracorporeal circulation. Conclusio- The patients who met the clinical criteria for postpericardiotomy syndrome were significan- tly younger than the others were. Serum markers for tissue injury and inflammatory response were not different in the clinically affected group, and did not correlate with the different types and duration of surgery or with extracorpo- real circulation. |
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Kohler, IlmarSaraiva, Paulo JaconiWender, Orlando Carlos BelmonteZago, Alcides José2010-04-16T09:11:12Z20030066-782Xhttp://hdl.handle.net/10183/19684000380141Objective- To verify the association of serum markers of myocardial injury, such as troponin I, creatinine kinase, and creatinine kinase isoenzyme MB, and inflammatory markers, such as tumor necrosis factor alpha (TNF-alpha), C-reactive protein, and the erythrocyte sedimentation rate in the perioperative period of cardiac surgery, with the occurrence of possible postpericardiotomy syndrome. Methods- This was a cohort study with 96 patients undergoing cardiac surgery assessed at the following 4 different time periods: the day before surgery (D0); the 3rd postoperative day (D3); between the 7th and 10th postoperative days (D7-10); and the 30th postoperative day (D30). During each period, we evaluated demo- graphic variables (sex and age), surgical variables (type and duration , extracorporeal circulation), and serum dosages of the markers of myocardial injury and inflam- matory response. Results - Of all patients, 12 (12.5%) met the clinical criteria for a diagnosis of postpericardiotomy syndrome, and their mean age was 10.3 years lower than the age of the others (P=0.02). The results of the serum markers for tissue injury and inflammatory response were not signifi- cantly different between the 2 assessed groups. No signifi- cant difference existed regarding either surgery duration or extracorporeal circulation. Conclusio- The patients who met the clinical criteria for postpericardiotomy syndrome were significan- tly younger than the others were. Serum markers for tissue injury and inflammatory response were not different in the clinically affected group, and did not correlate with the different types and duration of surgery or with extracorpo- real circulation.application/pdfporArquivos brasileiros de cardiologia. São Paulo. Vol. 81, n. 3 (sept. 2003), p. 279-284PericardiectomiaBiomarcadoresDiagnósticoTécnicas de laboratório clínicoCardiac surgeryInflammatory markersInjury markersPostpericardiotomy syndromeComportamento dos marcadores inflamatórios e de injúria miocárdica na cirurgia cardíaca : correlação laboratorial com quadro clínico de síndrome pós-pericardiotomiaBehavior of inflammatory markers of myocardial injury in cardiac surgery : laboratory correlation with the clinical picture of potpericardiotomy syndrome info:eu-repo/semantics/articleinfo:eu-repo/semantics/otherinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL000380141.pdf000380141.pdfTexto completo (inglês)application/pdf148115http://www.lume.ufrgs.br/bitstream/10183/19684/1/000380141.pdff18f65ad8b2f8177cc6ffe946874cad4MD51TEXT000380141.pdf.txt000380141.pdf.txtExtracted Texttext/plain30505http://www.lume.ufrgs.br/bitstream/10183/19684/2/000380141.pdf.txt7249e8a14b7f5b946c3723638f0f003aMD52THUMBNAIL000380141.pdf.jpg000380141.pdf.jpgGenerated Thumbnailimage/jpeg2191http://www.lume.ufrgs.br/bitstream/10183/19684/3/000380141.pdf.jpgd91ca1b77aa936d2594e293f57b946c7MD5310183/196842023-10-22 03:38:21.711607oai:www.lume.ufrgs.br:10183/19684Repositório InstitucionalPUBhttps://lume.ufrgs.br/oai/requestlume@ufrgs.bropendoar:2023-10-22T06:38:21Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Comportamento dos marcadores inflamatórios e de injúria miocárdica na cirurgia cardíaca : correlação laboratorial com quadro clínico de síndrome pós-pericardiotomia |
dc.title.alternative.en.fl_str_mv |
Behavior of inflammatory markers of myocardial injury in cardiac surgery : laboratory correlation with the clinical picture of potpericardiotomy syndrome |
title |
Comportamento dos marcadores inflamatórios e de injúria miocárdica na cirurgia cardíaca : correlação laboratorial com quadro clínico de síndrome pós-pericardiotomia |
spellingShingle |
Comportamento dos marcadores inflamatórios e de injúria miocárdica na cirurgia cardíaca : correlação laboratorial com quadro clínico de síndrome pós-pericardiotomia Kohler, Ilmar Pericardiectomia Biomarcadores Diagnóstico Técnicas de laboratório clínico Cardiac surgery Inflammatory markers Injury markers Postpericardiotomy syndrome |
title_short |
Comportamento dos marcadores inflamatórios e de injúria miocárdica na cirurgia cardíaca : correlação laboratorial com quadro clínico de síndrome pós-pericardiotomia |
title_full |
Comportamento dos marcadores inflamatórios e de injúria miocárdica na cirurgia cardíaca : correlação laboratorial com quadro clínico de síndrome pós-pericardiotomia |
title_fullStr |
Comportamento dos marcadores inflamatórios e de injúria miocárdica na cirurgia cardíaca : correlação laboratorial com quadro clínico de síndrome pós-pericardiotomia |
title_full_unstemmed |
Comportamento dos marcadores inflamatórios e de injúria miocárdica na cirurgia cardíaca : correlação laboratorial com quadro clínico de síndrome pós-pericardiotomia |
title_sort |
Comportamento dos marcadores inflamatórios e de injúria miocárdica na cirurgia cardíaca : correlação laboratorial com quadro clínico de síndrome pós-pericardiotomia |
author |
Kohler, Ilmar |
author_facet |
Kohler, Ilmar Saraiva, Paulo Jaconi Wender, Orlando Carlos Belmonte Zago, Alcides José |
author_role |
author |
author2 |
Saraiva, Paulo Jaconi Wender, Orlando Carlos Belmonte Zago, Alcides José |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Kohler, Ilmar Saraiva, Paulo Jaconi Wender, Orlando Carlos Belmonte Zago, Alcides José |
dc.subject.por.fl_str_mv |
Pericardiectomia Biomarcadores Diagnóstico Técnicas de laboratório clínico |
topic |
Pericardiectomia Biomarcadores Diagnóstico Técnicas de laboratório clínico Cardiac surgery Inflammatory markers Injury markers Postpericardiotomy syndrome |
dc.subject.eng.fl_str_mv |
Cardiac surgery Inflammatory markers Injury markers Postpericardiotomy syndrome |
description |
Objective- To verify the association of serum markers of myocardial injury, such as troponin I, creatinine kinase, and creatinine kinase isoenzyme MB, and inflammatory markers, such as tumor necrosis factor alpha (TNF-alpha), C-reactive protein, and the erythrocyte sedimentation rate in the perioperative period of cardiac surgery, with the occurrence of possible postpericardiotomy syndrome. Methods- This was a cohort study with 96 patients undergoing cardiac surgery assessed at the following 4 different time periods: the day before surgery (D0); the 3rd postoperative day (D3); between the 7th and 10th postoperative days (D7-10); and the 30th postoperative day (D30). During each period, we evaluated demo- graphic variables (sex and age), surgical variables (type and duration , extracorporeal circulation), and serum dosages of the markers of myocardial injury and inflam- matory response. Results - Of all patients, 12 (12.5%) met the clinical criteria for a diagnosis of postpericardiotomy syndrome, and their mean age was 10.3 years lower than the age of the others (P=0.02). The results of the serum markers for tissue injury and inflammatory response were not signifi- cantly different between the 2 assessed groups. No signifi- cant difference existed regarding either surgery duration or extracorporeal circulation. Conclusio- The patients who met the clinical criteria for postpericardiotomy syndrome were significan- tly younger than the others were. Serum markers for tissue injury and inflammatory response were not different in the clinically affected group, and did not correlate with the different types and duration of surgery or with extracorpo- real circulation. |
publishDate |
2003 |
dc.date.issued.fl_str_mv |
2003 |
dc.date.accessioned.fl_str_mv |
2010-04-16T09:11:12Z |
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http://hdl.handle.net/10183/19684 |
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0066-782X |
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000380141 |
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http://hdl.handle.net/10183/19684 |
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por |
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dc.relation.ispartof.pt_BR.fl_str_mv |
Arquivos brasileiros de cardiologia. São Paulo. Vol. 81, n. 3 (sept. 2003), p. 279-284 |
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