Carcinoma verrugoso en paciente joven

• Autor(a) principal: Rosa, Lauro Gilberto Nunes da
• Data de Publicação: 2003
• Outros Autores: Gedoz, Luhana, Hildebrand, Laura de Campos, Carvalho, Ana Luisa, Chevarria, Marcos Gonzales
• Tipo de documento: Artigo
• Idioma: spa
• Título da fonte: Repositório Institucional da UFRGS
• Texto Completo: http://hdl.handle.net/10183/49552
• topic: Radioterapia : Carcinoma bucal; Verrucous carcinoma; Radiotherapy; Child; Carcinoma verrucoso oral; Paciente joven

The verrucous carcinoma is a low grade variant of oral squamous cell carcinoma, and it mostly appears in the oral mucosa of individuals who chew tobacco chronically 6,8,10. The lesions are mainly found in men over 55 years old (average age 65 to 70 years) and the most common regions in the oral mucosa include the mandibular vestibule, jugal mucosa and hard palate 6,8. The lesion appears as a well-defined painless diffuse thick plaque with superficial papillary or verruciform projections. Under the microscope the presence of wide elongated interpapilIary ridges and copious keratin production are observed2. Metastasis is a rare event in verrucous carcinomas 6,8,9. The treatment of choice is surgical excision, optionally combined with radiotherapy. The authors report a c1inical case of a 13-year-old patient with a lesion compromising the whole lower Iip vermilion. The initial treatment proposed was radiotherapy combined with chemotherapy, due to the patient's age and the localization and extent of the lesion. After a total dose of 70Gy, full regression of the lesion took place. Thus, treatment of verrucous carcinoma by combining radiotherapy with chemotherapy proved satisfactory in this case.