Effects of high-intensity interval and moderate-intensity continuous exercise on inflammatory, leptin, IgA, and lipid peroxidation responses in obese males

• Autor(a) principal: Souza, Daniel Costa de
• Data de Publicação: 2018
• Outros Autores: Matos, Victor Araújo Ferreira, Santos, Victor Oliveira Albuquerque dos, Medeiros, Ítalo Freire, Marinho, Cristiane da Silva Ramos, Nascimento, Paulo Ricardo Porfírio do, Dorneles, Gilson Pires, Peres, Alessandra, Muller, Carlos Henrique de Lemos, Krause, Maurício da Silva, Costa, Eduardo Caldas, Fayh, Ana Paula Trussardi
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UFRGS
• Texto Completo: http://hdl.handle.net/10183/195899
• topic: Treinamento intervalado de alta intensidade; Leptina; Obesidade; Exercício; Obesity; Aerobic exercise; High-intensity interval training; Cytokines; Immunoglobulin-A; Lipoperoxidation

Purpose: To compare the effects of a single high-intensity interval exercise session (HIIE) with amoderate-intensity continuous exercise session (MICE) on the inflammatory profile, IgA levels, and lipid peroxidation in sedentary obese males. Methods: Ten sedentary obese men (age 28.5 ± 2.7 years; BMI 35.9 ± 4.9 kg/m2; body fat 40.6 ± 2.0%) performed three experimental sessions, on separate days with 1 week wash-out period between interventions, according to a randomized order: (1) HIIE: 10 × 60 s at 90% of the HRmax alternated by 60 s of active recovery; (2) MICE: 20min at 70% of the HRmax; (3) Rest—control. Blood and saliva samples were collected before, immediately after and 60min after the end of each session in order to analyse serum levels of cytokines, IgA, and lipoperoxidation markers. Results: Leptin levels decreased immediately after HIIE (P = 0.033) and was different from the MICE (P = 0.025). IFN-g levels were reduced immediately after (P = 0.032) and 60min after HIIE (P = 0.003) compared to baseline, and it also increased IL-4 levels immediately after exercise (P = 0.007) compared to resting values. MICE promoted an increase in IFN-g levels immediately after exercise (P = 0.025) and 60min after exercise (P = 0.004) in relation to baseline. Both exercise conditions increased IL-6 levels up to 60min after exercise (P < 0.05). The IFN-g/IL-4 ratio decreased immediately after (P = 0.002) and 60min after HIIE (P = 0.005) in relation to pre-exercise. No changes were found for IgA-S and TBARS for any of the conditions. Conclusion: A single HIIE session is able to decrease IFN-g/IL-4 ratio, indicating an anti-inflammatory response, without alterations in the function of the mucosal immune systemand lipoperoxidation. On the other hand, a brief session ofMICE induced changes in the pattern of cytokines associated with increased cellular immune function.