HoBi-like Pestivirus is highly prevalent in cattle herds in the Amazon Region (northern Brazil)

• Autor(a) principal: Baumbach, Leticia Ferreira
• Data de Publicação: 2023
• Outros Autores: Mósena, Ana Cristina Sbaraini, Alves, Raquel Silva, Camargo, Laura Junqueira de, Olegário, Juliana do Canto, Silva, Leonardo Reis Lobraico da, Costa, João Marcos Nacif da, Borba, Mauro Riegert, Bauermann, Fernando Vicosa, Weber, Matheus Nunes, Canal, Cláudio Wageck
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UFRGS
• Texto Completo: http://hdl.handle.net/10183/257280
• topic: Infecções por pestivirus; Vírus da diarréia viral bovina; HoBi-like; Variação genética; Bovinos; Brasil, Região Norte; BVDV; Serum neutralization; Phylogeny; Epidemiology

Pestiviruses are globally distributed and cause substantial economic losses to the cattle industry. In Brazil, the country with the world’s largest cattle population, pestivirus infections are well described in some regions, such as in the south, where a high frequency of BVDV-2 is described and contrasts with the high prevalence of HoBi-like pestivirus (HoBiPeV) in the northeast. However, there is a lack of information about pestiviruses in the Amazon Region, in northern Brazil, with a cattle population estimated at 55.7 million head, which has a significant impact on the international livestock market. Therefore, this study investigated the seroprevalence and genetic variability of ruminant pestiviruses in 944 bovine serum samples from four states in northern Brazil: Pará (PA), Amapá (AP), Roraima (RR), and Amazonas (AM). Our results showed that 45.4% of the samples were seropositive (19.8% for BVDV-1, 14.1% for BVDV-2, and 20.9% for HoBiPeV). All samples were tested by RT–qPCR, and three were positive and classified as HoBiPeV in a phylogenetic analysis. These serological and molecular results contrast with those from other regions of the world, suggesting that the northern Brazilian states have a high prevalence of all bovine pestiviruses including HoBiPeV.