Atividade do Nucleus Reuniens é necessária para a reconsolidação de uma memória de medo contextual
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Tipo de documento: | Trabalho de conclusão de curso |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/248219 |
Resumo: | Memory reconsolidation is the process by which a consolidated memory can changed or disrupt by amnesic agents or behavioral interferences. This process require the activity of many neural structures conform the behavior task. In aversive memories pre-frontal cortex and hippocampus activity is critical to correct reconsolidation of the memory trace. Nucleus reuniens is the largest nucleus of midline thalamic nuclei and makes a bridge of communication between mPFC and HP. In this work we tested the effects of the excitatory activity and protein synthesis on NR during the reactivation of aversive memory on the reconsolidation process. We found a critic role of excitatory activity of NR in the reconsolidation of memory, but we not found any effect of protein synthesis of NR in the phenomena. We conclude that there is a modulator effect of NR during the reactivation that can affect the reconsolidation of the memory. |
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Machado, Adriano EmanuelQuillfeldt, Jorge AlbertoAlvares, Lucas de Oliveira2022-08-30T04:58:06Z2015http://hdl.handle.net/10183/248219000991534Memory reconsolidation is the process by which a consolidated memory can changed or disrupt by amnesic agents or behavioral interferences. This process require the activity of many neural structures conform the behavior task. In aversive memories pre-frontal cortex and hippocampus activity is critical to correct reconsolidation of the memory trace. Nucleus reuniens is the largest nucleus of midline thalamic nuclei and makes a bridge of communication between mPFC and HP. In this work we tested the effects of the excitatory activity and protein synthesis on NR during the reactivation of aversive memory on the reconsolidation process. We found a critic role of excitatory activity of NR in the reconsolidation of memory, but we not found any effect of protein synthesis of NR in the phenomena. We conclude that there is a modulator effect of NR during the reactivation that can affect the reconsolidation of the memory.application/pdfengMemória aversivaNúcleos talâmicosAtividade do Nucleus Reuniens é necessária para a reconsolidação de uma memória de medo contextualinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bachelorThesisUniversidade Federal do Rio Grande do SulInstituto de BiociênciasPorto Alegre, BR-RS2015Ciências Biológicas: Bachareladograduaçãoinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT000991534.pdf.txt000991534.pdf.txtExtracted Texttext/plain24989http://www.lume.ufrgs.br/bitstream/10183/248219/2/000991534.pdf.txtbbd9fdf32e2ecd5711aa057f410a0117MD52ORIGINAL000991534.pdfTexto completo (inglês)application/pdf293149http://www.lume.ufrgs.br/bitstream/10183/248219/1/000991534.pdf39130bb9b69e92bd37e547a4c2382ce1MD5110183/2482192022-08-31 04:56:51.219829oai:www.lume.ufrgs.br:10183/248219Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2022-08-31T07:56:51Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Atividade do Nucleus Reuniens é necessária para a reconsolidação de uma memória de medo contextual |
title |
Atividade do Nucleus Reuniens é necessária para a reconsolidação de uma memória de medo contextual |
spellingShingle |
Atividade do Nucleus Reuniens é necessária para a reconsolidação de uma memória de medo contextual Machado, Adriano Emanuel Memória aversiva Núcleos talâmicos |
title_short |
Atividade do Nucleus Reuniens é necessária para a reconsolidação de uma memória de medo contextual |
title_full |
Atividade do Nucleus Reuniens é necessária para a reconsolidação de uma memória de medo contextual |
title_fullStr |
Atividade do Nucleus Reuniens é necessária para a reconsolidação de uma memória de medo contextual |
title_full_unstemmed |
Atividade do Nucleus Reuniens é necessária para a reconsolidação de uma memória de medo contextual |
title_sort |
Atividade do Nucleus Reuniens é necessária para a reconsolidação de uma memória de medo contextual |
author |
Machado, Adriano Emanuel |
author_facet |
Machado, Adriano Emanuel |
author_role |
author |
dc.contributor.author.fl_str_mv |
Machado, Adriano Emanuel |
dc.contributor.advisor1.fl_str_mv |
Quillfeldt, Jorge Alberto |
dc.contributor.advisor-co1.fl_str_mv |
Alvares, Lucas de Oliveira |
contributor_str_mv |
Quillfeldt, Jorge Alberto Alvares, Lucas de Oliveira |
dc.subject.por.fl_str_mv |
Memória aversiva Núcleos talâmicos |
topic |
Memória aversiva Núcleos talâmicos |
description |
Memory reconsolidation is the process by which a consolidated memory can changed or disrupt by amnesic agents or behavioral interferences. This process require the activity of many neural structures conform the behavior task. In aversive memories pre-frontal cortex and hippocampus activity is critical to correct reconsolidation of the memory trace. Nucleus reuniens is the largest nucleus of midline thalamic nuclei and makes a bridge of communication between mPFC and HP. In this work we tested the effects of the excitatory activity and protein synthesis on NR during the reactivation of aversive memory on the reconsolidation process. We found a critic role of excitatory activity of NR in the reconsolidation of memory, but we not found any effect of protein synthesis of NR in the phenomena. We conclude that there is a modulator effect of NR during the reactivation that can affect the reconsolidation of the memory. |
publishDate |
2015 |
dc.date.issued.fl_str_mv |
2015 |
dc.date.accessioned.fl_str_mv |
2022-08-30T04:58:06Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/bachelorThesis |
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bachelorThesis |
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publishedVersion |
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http://hdl.handle.net/10183/248219 |
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000991534 |
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eng |
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