Fiber intake and inflammation in type 1 diabetes
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/110250 |
Resumo: | Background: Higher intake of dietary fiber is associated with lower risk of coronary heart disease, the leading cause of mortality among people with type 1 diabetes. The protective effect includes the anti-inflammatory properties of some foods. Population-based studies have shown an inverse association between some nutritional habits and high sensitive -C-reactive protein (hs-CRP). This study aimed to ascertain the association between fiber intake and hs-CPR levels in patients with type 1 diabetes. Methods: This cross-sectional study was conducted with 106 outpatients with type 1 diabetes; age 40 ± 11 years; diabetes duration of 18 ± 8.8 years. Dietary intake was evaluated by 3-day weighed-diet records. Patients were categorized in 2 groups, according to fiber intake (>20 g/day and <20 g/day). Results: The group with fiber intake > 20 g/day had lower hs-CRP levels [median (25th-75th) 0.7 mg/dl (0.4-2.4) vs. 1.9 mg/dl (1.0-4.4); P = 0.002], than the other group. Controlled for HbA1c and energy intake, an inverse relation was observed between hs-CRP levels and total fiber [ß = − 0.030 (SE: 0.0120), P = 0.02], soluble fiber [ß = − 0.078 (SE: 0.0421), P = 0.06] and insoluble fiber [ß = − 0.039 (SE: 0.01761), P = 0.026]. Even, after additional adjustment fibers remained associated with lower hs-CRP levels. Total fibers were stratified in 4 groups: < 10 g/day, from 10 to < 20 g/day, from 20 to 30 g/day and > 30 g/day. Compared to the group who ingested < 10 g/day of total fiber (referent group), the group who consumed > 30 g/d had significantly lower hs-CRP levels [−2.45 mg/L, P = 0.012] independent of the HbA1c values. Conclusions: The present study suggests that an increased consumption of dietary fiber > 30 g/day may play a role in reducing inflammation in individuals with type 1 diabetes. |
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Bernaud, Fernanda Sarmento RollaBeretta, Mileni VantiNascimento, Cigléa doEscobar, Fabrícia TeixeiraGross, Jorge LuizAzevedo, Mirela Jobim deRodrigues, Ticiana da Costa2015-02-20T02:20:44Z20141758-5996http://hdl.handle.net/10183/110250000942491Background: Higher intake of dietary fiber is associated with lower risk of coronary heart disease, the leading cause of mortality among people with type 1 diabetes. The protective effect includes the anti-inflammatory properties of some foods. Population-based studies have shown an inverse association between some nutritional habits and high sensitive -C-reactive protein (hs-CRP). This study aimed to ascertain the association between fiber intake and hs-CPR levels in patients with type 1 diabetes. Methods: This cross-sectional study was conducted with 106 outpatients with type 1 diabetes; age 40 ± 11 years; diabetes duration of 18 ± 8.8 years. Dietary intake was evaluated by 3-day weighed-diet records. Patients were categorized in 2 groups, according to fiber intake (>20 g/day and <20 g/day). Results: The group with fiber intake > 20 g/day had lower hs-CRP levels [median (25th-75th) 0.7 mg/dl (0.4-2.4) vs. 1.9 mg/dl (1.0-4.4); P = 0.002], than the other group. Controlled for HbA1c and energy intake, an inverse relation was observed between hs-CRP levels and total fiber [ß = − 0.030 (SE: 0.0120), P = 0.02], soluble fiber [ß = − 0.078 (SE: 0.0421), P = 0.06] and insoluble fiber [ß = − 0.039 (SE: 0.01761), P = 0.026]. Even, after additional adjustment fibers remained associated with lower hs-CRP levels. Total fibers were stratified in 4 groups: < 10 g/day, from 10 to < 20 g/day, from 20 to 30 g/day and > 30 g/day. Compared to the group who ingested < 10 g/day of total fiber (referent group), the group who consumed > 30 g/d had significantly lower hs-CRP levels [−2.45 mg/L, P = 0.012] independent of the HbA1c values. Conclusions: The present study suggests that an increased consumption of dietary fiber > 30 g/day may play a role in reducing inflammation in individuals with type 1 diabetes.application/pdfengDiabetology and metabolic syndrome. [London]. Vol. 6 (May 2014), [10] p.Diabetes mellitus tipo 1InflamaçãoFibras na dietaType 1 diabetes,Fiber intakeInflammationFiber intake and inflammation in type 1 diabetesEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL000942491.pdf000942491.pdfTexto completo (inglês)application/pdf425860http://www.lume.ufrgs.br/bitstream/10183/110250/1/000942491.pdfdc7e4f3d7ed21f98e73d469887862965MD51TEXT000942491.pdf.txt000942491.pdf.txtExtracted Texttext/plain52731http://www.lume.ufrgs.br/bitstream/10183/110250/2/000942491.pdf.txt054f9ef591e237fc2d053f2b0f061ec9MD52THUMBNAIL000942491.pdf.jpg000942491.pdf.jpgGenerated Thumbnailimage/jpeg2063http://www.lume.ufrgs.br/bitstream/10183/110250/3/000942491.pdf.jpg3136f8277f14020ab0497df846f92222MD5310183/1102502021-03-09 04:54:09.49833oai:www.lume.ufrgs.br:10183/110250Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2021-03-09T07:54:09Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Fiber intake and inflammation in type 1 diabetes |
title |
Fiber intake and inflammation in type 1 diabetes |
spellingShingle |
Fiber intake and inflammation in type 1 diabetes Bernaud, Fernanda Sarmento Rolla Diabetes mellitus tipo 1 Inflamação Fibras na dieta Type 1 diabetes, Fiber intake Inflammation |
title_short |
Fiber intake and inflammation in type 1 diabetes |
title_full |
Fiber intake and inflammation in type 1 diabetes |
title_fullStr |
Fiber intake and inflammation in type 1 diabetes |
title_full_unstemmed |
Fiber intake and inflammation in type 1 diabetes |
title_sort |
Fiber intake and inflammation in type 1 diabetes |
author |
Bernaud, Fernanda Sarmento Rolla |
author_facet |
Bernaud, Fernanda Sarmento Rolla Beretta, Mileni Vanti Nascimento, Cigléa do Escobar, Fabrícia Teixeira Gross, Jorge Luiz Azevedo, Mirela Jobim de Rodrigues, Ticiana da Costa |
author_role |
author |
author2 |
Beretta, Mileni Vanti Nascimento, Cigléa do Escobar, Fabrícia Teixeira Gross, Jorge Luiz Azevedo, Mirela Jobim de Rodrigues, Ticiana da Costa |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Bernaud, Fernanda Sarmento Rolla Beretta, Mileni Vanti Nascimento, Cigléa do Escobar, Fabrícia Teixeira Gross, Jorge Luiz Azevedo, Mirela Jobim de Rodrigues, Ticiana da Costa |
dc.subject.por.fl_str_mv |
Diabetes mellitus tipo 1 Inflamação Fibras na dieta |
topic |
Diabetes mellitus tipo 1 Inflamação Fibras na dieta Type 1 diabetes, Fiber intake Inflammation |
dc.subject.eng.fl_str_mv |
Type 1 diabetes, Fiber intake Inflammation |
description |
Background: Higher intake of dietary fiber is associated with lower risk of coronary heart disease, the leading cause of mortality among people with type 1 diabetes. The protective effect includes the anti-inflammatory properties of some foods. Population-based studies have shown an inverse association between some nutritional habits and high sensitive -C-reactive protein (hs-CRP). This study aimed to ascertain the association between fiber intake and hs-CPR levels in patients with type 1 diabetes. Methods: This cross-sectional study was conducted with 106 outpatients with type 1 diabetes; age 40 ± 11 years; diabetes duration of 18 ± 8.8 years. Dietary intake was evaluated by 3-day weighed-diet records. Patients were categorized in 2 groups, according to fiber intake (>20 g/day and <20 g/day). Results: The group with fiber intake > 20 g/day had lower hs-CRP levels [median (25th-75th) 0.7 mg/dl (0.4-2.4) vs. 1.9 mg/dl (1.0-4.4); P = 0.002], than the other group. Controlled for HbA1c and energy intake, an inverse relation was observed between hs-CRP levels and total fiber [ß = − 0.030 (SE: 0.0120), P = 0.02], soluble fiber [ß = − 0.078 (SE: 0.0421), P = 0.06] and insoluble fiber [ß = − 0.039 (SE: 0.01761), P = 0.026]. Even, after additional adjustment fibers remained associated with lower hs-CRP levels. Total fibers were stratified in 4 groups: < 10 g/day, from 10 to < 20 g/day, from 20 to 30 g/day and > 30 g/day. Compared to the group who ingested < 10 g/day of total fiber (referent group), the group who consumed > 30 g/d had significantly lower hs-CRP levels [−2.45 mg/L, P = 0.012] independent of the HbA1c values. Conclusions: The present study suggests that an increased consumption of dietary fiber > 30 g/day may play a role in reducing inflammation in individuals with type 1 diabetes. |
publishDate |
2014 |
dc.date.issued.fl_str_mv |
2014 |
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2015-02-20T02:20:44Z |
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1758-5996 |
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000942491 |
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dc.relation.ispartof.pt_BR.fl_str_mv |
Diabetology and metabolic syndrome. [London]. Vol. 6 (May 2014), [10] p. |
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openAccess |
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